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Mark Gladwin, MD, Pulmonology, Bethesda, MD

Mark Thomas Gladwin MD

Pulmonology•Bethesda, MD

Critical Care Medicine, Pleural Disease

Vice President for Medical Affairs, University of Maryland, Baltimore and John Z. and Akiko K. Bowers Distinguished Professor and Dean, University of Maryland School of Medicine

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  • Rockville PikeBldg 10Bethesda, MD 20892

  • Phone+1 301-435-2310

  • Fax+1 412-647-4050

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Education & Training

  • National Institutes of Health Clinical Center
    National Institutes of Health Clinical CenterFellowship, Critical Care Medicine (Internal Medicine), 1995 - 1999
  • University of Washington
    University of WashingtonFellowship, Pulmonary Disease and Critical Care Medicine, 1996 - 1998
  • Oregon Health & Science University (OHSU Health)
    Oregon Health & Science University (OHSU Health)Residency, Internal Medicine, 1991 - 1995
  • University of Miami Leonard M. Miller School of Medicine
    University of Miami Leonard M. Miller School of MedicineClass of 1991

Certifications & Licensure

  • OR State Medical License
    OR State Medical License 1992 - Present
  • MD State Medical License
    MD State Medical License 1997 - 2026
  • PA State Medical License
    PA State Medical License 2008 - 2024
  • DC State Medical License
    DC State Medical License 1997 - 2004
  • Critical Care Medicine
    American Board of Internal Medicine Critical Care Medicine
  • Pulmonary Disease
    American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

  • CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
  • Elected Member The American Society for Clinical Investigation, 2006

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Intradonor Reproducibility and Changes in Hemolytic Variables During Red Blood Cell Storage: Results of Recall Phase of the REDS‐III RBC‐Omics Study  
    Darrell J Triulzi, Mark T Gladwin, Alan E Mast, Michael P Busch, Transfusion
  • Impact of Different Standard Red Blood Cell Storage Temperatures on Human and Canine RBC Hemolysis and Chromium Survival  
    Charles Natanson, Kamille West, Kevin P Blaine, Mark T Gladwin, Transfusion

Abstracts/Posters

  • Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression
    Mark T Gladwin, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
  • Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia
    Mark T Gladwin, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
  • Innate Immune Mechanism of Hemarthrosis in Hemophilia-a Mice
    Mark T Gladwin, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures

  • Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Regulatory Genetic Variation at the S100B Gene Associates with Vaso-Occlusive Manifestations in Sickle Cell Disease 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Heterogeneity of Blood Processing and Storage Additives in Different Centers Impacts Stored Red Blood Cell Metabolism as Much as Storage Time: Lessons from REDS‐III—Omics 
    UPMC Life Changing Medicine, Philadelphia, Pennsylvania - 10/5/2012

Authored Content

  • Drs. Terence S. Dermody & Mark Gladwin: Thanks to Pittsburgh for Leadership in Covid-19 CrisisApril 2020
  • Drs. Terence S. Dermody & Mark Gladwin: Thanks to Pittsburgh for Leadership in Covid-19 CrisisApril 2020

Press Mentions

  • Brain Chemistry Discovery Explains Why Ritalin Helps Some More Than Others Todayheadline
    Brain Chemistry Discovery Explains Why Ritalin Helps Some More Than Others TodayheadlineApril 2nd, 2025
  • Key Brain Differences Can Explain Why Ritalin Helps Improve Focus in Some More Than Others
    Key Brain Differences Can Explain Why Ritalin Helps Improve Focus in Some More Than OthersApril 2nd, 2025
  • UMSOM Rising Third-Year Medical Students Celebrate Transition to Clinical Care Training at Annual Student Clinician Ceremony
    UMSOM Rising Third-Year Medical Students Celebrate Transition to Clinical Care Training at Annual Student Clinician CeremonyMarch 13th, 2025
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Grant Support

  • Omics, mice and men: Development of precision transfusion medicineUNIVERSITY OF MARYLAND BALTIMORE2009–2028
  • Airway epithelial cytoglobin regulates nitric oxide synthase and development of primary ciliary dyskinesia and situs inversusUNIVERSITY OF MARYLAND BALTIMORE2023–2027
  • Airway epithelial cytoglobin regulates nitric oxide synthase and development of primary ciliary dyskinesia and situs inversusUNIVERSITY OF MARYLAND BALTIMORE2023–2027
  • Airway epithelial cytoglobin regulates nitric oxide synthase and development of primary ciliary dyskinesia and situs inversusUNIVERSITY OF MARYLAND BALTIMORE2023–2027
  • Airway epithelial cytoglobin regulates nitric oxide synthase and development of primary ciliary dyskinesia and situs inversusUNIVERSITY OF MARYLAND BALTIMORE2023–2027
  • Antidote for inhaled CO poisoning based on mutationally engineered neuroglobinUNIVERSITY OF MARYLAND BALTIMORE2014–2027
  • Antidote for inhaled CO poisoning based on mutationally engineered neuroglobinUNIVERSITY OF MARYLAND BALTIMORE2014–2027
  • Sickle Cell Disease and Cardiovascular Risk- Red Cell Exchange SCD-CARREUNIVERSITY OF MARYLAND BALTIMORE2022–2026
  • Translational Pulmonary Vascular BiologyNational Heart, Lung, And Blood Institute2012
  • Myoglobin As A Nitrite Reductase That Regulates Hypoxic Cardiac NO SignalingNational Heart, Lung, And Blood Institute2010–2012
  • Vascular Subphenotypes Of Lung DiseaseNational Heart, Lung, And Blood Institute2011
  • Pulmonary Vascular-Targeted NO Therapeutic StrategiesNational Heart, Lung, And Blood Institute2011
  • Administrative CoreNational Heart, Lung, And Blood Institute2011
  • Dietary Nitrate Activation Of Ppargamma Improves Insulin SensitivityNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2010
  • Translational Vascular Biology In Autoimmune DiseasesNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2009–2010
  • Nitric Oxide For Patients With Sickle Cell Anemia And Pulmonary HypertensionClinical Center2008
  • Use Of Hydroxyurea &L-Arginine Or Sildenafil In Patients W/Sickle Cell DiseaseNational Heart, Lung, And Blood Institute2007–2008
  • Systemic Nitrite Infusion And Its Effect On Exercise Physiology And MetabolismNational Heart, Lung, And Blood Institute2007–2008
  • Synergy Of Hydroxyurea And Erythropoietin On Fetal Hemoglobin In SCDNational Heart, Lung, And Blood Institute2007–2008
  • Multicenter Trial Of NO For Acute Treatment Of Sickle Cell Pain EpisodesNational Heart, Lung, And Blood Institute2007–2008
  • Hemolysis, NO And PAH In MalariaNational Heart, Lung, And Blood Institute2007–2008
  • Prevalence And Prognosis Of Pulmonary Hypertension In Adults With Sickle CellClinical Center2007–2008
  • Blood Studies Of Endothelial Function And Systemic InflammationClinical Center2007–2008
  • Prevalence Of PAH In SCD Patients In NigeriaNational Heart, Lung, And Blood Institute2006–2008
  • Nitrite Infusion Studies On Healthy VolunteersNational Heart, Lung, And Blood Institute2005–2008
  • Use Of Bosentan In Patients With Symptomatic PH Associated With SCDNational Heart, Lung, And Blood Institute2007
  • Evaluation Of Endothelial Function In HIV Associated PAHClinical Center2007
  • Cardiopulmonary Function Assessment And NO Based Therapies For SCD PTS With PAHClinical Center2007
  • Use Of Hydroxyurea &L-Arginine Or Sildenafil In PatientNational Heart, Lung, And Blood Institute2006
  • Synergy Of Hydroxyurea And Erythropoietin On Fetal HemogNational Heart, Lung, And Blood Institute2006
  • Systemic Nitrite Infusion And Its Effect On Exercise PhyNational Heart, Lung, And Blood Institute2005–2006
  • Multicenter Trial Of NO For Acute Treatment Of Sickle CENational Heart, Lung, And Blood Institute2005–2006
  • Blood Studies Of Endothelial Function And Systemic InflaClinical Center2005–2006
  • Prevalence And Prognosis Of Pulmonary Hypertension In ADClinical Center2001–2006
  • Nitric Oxide For Patients With Sickle Cell Anemia And PuClinical Center2001–2006
  • Use Of Hydroxyurea &L-Arginine Or Sildenafil In SCDClinical Center2005
  • Prevalence And Prognosis Of Pulmonary Hypertension In ADClinical Center2005
  • Sickle Cell: Risk/Prognosis Of Pulmonary HypertensionClinical Center2004
  • Nitric Oxide: Sickle Cell Anemia/Pulmonary HypertensionClinical Center2004
  • Hydroxyurea/L-Arginine Or Sildenafil Sickle Cell DiseaseClinical Center2004
  • Blood Studies Endothelial Function/Systemic InflammationClinical Center2004
  • Hydroxyurea &L-Arginine Or Sildenafil In Patients W/ScdClinical Center2003
  • Blood Studies Of Endothelial Function /Systemic InflammaClinical Center2003
  • Physiologic Effects Of Inhaled Nitric Oxide, NitroglycerClinical Center2001–2002
  • Delivery Of NO By Hemoglobin To Improve Blood Flow In SIClinical Center2001–2002
  • Effects Of Endothelium-Derived Versus Hemoglobin-TranspoClinical Center2001
  • Physiologic Effects Of Inhaled Nitric Oxide, Nitroglycerin, And Placebo In StudyClinical Center1998–2000

External Links

  • Physician Summaryhttps://www.umaryland.edu/about-umb/university-leadership/mark-t-gladwin-md/

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Dr. Mark Gladwin, Dr. Mark Gladwin, MD, Dr. M Gladwin, Dr. Mark Thomas Gladwin