MarkSGeorgeMD

Distinguished Professor of Psychiatry, Radiology and Neuroscience Layton McCurdy Endowed Chair Director, Brain Stimulation Laboratory at MUSC

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Office
171 Ashley Ave
Charleston, SC 29425
Phone+1 843-792-1414

Education & Training

National Institutes of Health Clinical CenterResidency, Psychiatry, 1991 - 1993
Medical University of South CarolinaResidency, Psychiatry, 1985 - 1990
Medical University of South CarolinaClass of 1985

Certifications & Licensure

SC State Medical License 1986 - 2025
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Psychiatry

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Magnetic Brain Stimulation for the Treatment of Adult Depression Start of enrollment: 2005 Feb 01
Completed
Phase 2, Phase 3
Treatment-Resistant Depression Registry Start of enrollment: 2006 Jan 01
Completed
Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation Start of enrollment: 2010 Oct 01
Unknown status
Phase 3
The Impact of Real-time Functional Magnetic Resonance Imaging (fMRI) Feedback on Response to Nicotine Cues Start of enrollment: 2010 Mar 01
Terminated
Safety and Efficacy Study of Deep Transcranial Magnetic Stimulation in Bipolar Depression Start of enrollment: 2012 May 01
Unknown status
Not Applicable
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 1 Start of enrollment: 2013 Apr 01
Terminated
Not Applicable
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2 Start of enrollment: 2013 Mar 01
Terminated
Not Applicable
Evaluation of Deep Transcranial Magnetic Stimulation (DTMS) With the H-ADD Coil as an Aid to Smoking Cessation. Start of enrollment: 2014 Aug 20
Completed
Phase 3
A Safety & Efficacy Study With Deep Transcranial Magnetic Stimulation for the Treatment of Post-Traumatic Stress Disorder (PTSD) Start of enrollment: 2016 Nov 17
Terminated
Not Applicable
Focal Electrically-Administered Seizure Therapy (FEAST) Studies at Two Enrolling Sites to Further Test and Refine the Treatment Start of enrollment: 2015 Aug 01
Completed
Phase 2, Phase 3
Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents Start of enrollment: 2015 Oct 01
Unknown status
Not Applicable
taVNS Paired With Bottle Feeding in Infants Failing Oral Feeds Start of enrollment: 2017 Oct 01
Completed
Early Phase 1
Individualizing tDCS Dose Start of enrollment: 2024 May 31
Recruiting
Not Applicable
Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD) Start of enrollment: 2021 Jul 26
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
tFUS Induced Transient Scotoma for Individual Dosing Start of enrollment: 2024 Jun 20
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
taVNS or TMS or Both for Depression Start of enrollment: 2023 Mar 14
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

TMS-induced modulation of brain networks and its associations to rTMS treatment for depression: a concurrent fMRI-EEG-TMS study.
Hengda He, Xiaoxiao Sun, Jayce Doose, Josef Faller, James R McIntosh
Medrxiv. 2024-12-27
1 citations
Effects of vagus nerve stimulation on daily function and quality of life in markedly treatment-resistant major depression: Findings from a one-year, randomized, sham-c...
A John Rush, Charles R Conway, Scott T Aaronson, Mark S George, Patricio Riva-Posse
Brain Stimulation. 2024-12-18
1 citations
Vagus nerve stimulation in treatment-resistant depression: A one-year, randomized, sham-controlled trial.
Charles R Conway, Scott T Aaronson, Harold A Sackeim, Mark S George, John Zajecka
Brain Stimulation. 2024-12-18

Lectures

American Psychiatric Association Publishing
American College of Physicians, Hilton Head Island, South Carolina - 10/11/2012
26th Annual Update: Disaster, Trauma & Recovery
Medical University of South Carolina Office of CME, Charleston, North Carolina - 5/30/2013

Press Mentions

Quicker, More Intense Brain Stimulation Begun at MUSC Shows Success in DepressionAugust 19th, 2024
Electroconvulsive Therapy Works, Now Scientists Believe They Know HowAugust 7th, 2024
Stimulating Hope: Personalizing Treatment Options for DepressionMay 10th, 2023
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Grant Support

The Impact Of Real-Time FMRI Feedback On Response To Nicotine CuesNational Institute On Drug Abuse2010–2011
Optimization Of TMS For Depression - Coordinating CenterNational Center For Research Resources2009–2010
The Impact Of Real-Time FMRI Feedback On Response To Nicotine CuesNational Institute On Drug Abuse2008–2009
Optimization Of TMS For Depression - Coordinating CenterNational Institute Of Mental Health2004–2009
Optimization Of TMS For DepressionNational Institute Of Mental Health2004–2009
MRI Study On Cerebral Activation During Specific Hand- And Finger-TasksNational Center For Research Resources2006–2008
Pilot Study Assessing The Effects Of Dar-0100 On Brain Activity In SchizophreniaNational Center For Research Resources2005
Efficacy/Safety Of Single Dose Of Ampakine (R) CX516National Center For Research Resources2004
Creating A Man-Portable Transcranial Magnetic Stimulation SystemNational Center For Research Resources2004
Mood Effects Of Deep Brain Stimulation In ParkinsonsNational Institute Of Neurological Disorders And Stroke2000–2002

Professional Memberships

American Psychiatric Association - APA
Member