MarkAndrewFryeMD

PubMed

• Delays in bipolar depression treatment in primary care vs. integrated behavioral health and specialty care.
  Jin Hong Park, Scott A Breitinger, Samuel T Savitz, Manuel Gardea-Resendez, Balwinder Singh
  Journal of Affective Disorders. 2025-01-15
• Differential serum levels of CACNA1C, circadian rhythm and stress response molecules in subjects with bipolar disorder: Associations with genetic and clinical factors.
  Obie Allen 4th, Brandon J Coombes, Vanessa Pazdernik, Barbara Gisabella, Joshua Hartley
  Journal of Affective Disorders. 2024-12-15
• Association between exposure to antidepressants and stimulants and age at onset of mania or psychosis: A retrospective population-based cohort study.
  Alessandro Miola, Mete Ercis, Vanessa K Pazdernik, Manuel Fuentes Salgado, Javier Ortiz-Orendain
  European Neuropsychopharmacology. 2024-12-01

Journal Articles

• Research Paper Sex-Specific Effects of Gain-of-Function P2RX7 Variation on Bipolar Disorder  
  William V Bobo, Mark A Frye, ScienceDirect
• More pernicious course of bipolar disorder in the United States than in many European countries: Implications for policy and treatment  
  Post RM, Altshuler L, Kupka R, McElroy S, Frye MA, Rowe M, Leverich GS, Grunze H, Suppes T, Keck PE Jr, Nolen WA, J Affect Disord, 1/1/2014
• More medical comorbidities in patients with bipolar disorder from the United States than from the Netherlands and Germany  
  Post RM, Altshuler LL, Leverich GS, Frye MA, Suppes T, McElroy SL, Keck PE Jr, Nolen WA, Kupka RW, Grunze H, Rowe M, J Nerv Ment Dis, 1/1/2014
• A multinational study to pilot the modified Hypomania Checklist (mHCL) in the assessment of mixed depression  
  Altinbas K, Ozerdem A, Prieto ML, Fuentes ME, Yalin N, Ersoy Z, Aydemir O, Quiroz D, Oztekin S, Geske JR, Feeder SE, Angst J, Frye MA, J Affect Disord, 1/1/2014
• Supraphysiologic doses of levothyroxine as adjunctive therapy in bipolar depression: A randomized, double-blind, placebo-controlled study  
  Stamm TJ, Lewitzka U, Sauer C, Pilhatsch M, Smolka MN, Koeberle U, Adli M, Ricken R, Scherk H, Frye MA, Juckel G, Assion HJ, Gitlin M, Whybrow PC, Bauer M, J Clin Psychiatry, 1/1/2014
• Feasibility evaluation of an interpersonal and social rhythm therapy group delivery model  
  Hoberg AA, Vickers KS, Ericksen J, Bauer G, Kung S, Stone R, Williams M, Moore MJ, Frye MA, Arch Psychiatr Nurs, 1/1/2013
• Assessment of response to lithium maintenance treatment in bipolar disorder: A consortium on lithium genetics (ConLiGen) report  
  Manchia M, Adli M, Akula N, Ardau R, Aubry JM, Backlund L, Banzato CE, Baune BT, Bellivier F, Bengesser S, Biernacka JM, Brichant-Petitjean C, Bui E, Calkin CV, Cheng ..., PLoS ONE, 1/1/2013
• Hypovitaminosis D in psychiatric inpatients: clinical correlation with depressive symptoms, cognitive impairment, and prescribing practices  
  Leedahl DD, Cunningham JL, Drake MT, Mundis CB, Kung S, Frye MA, Lapid MI, Psychosomatics, 1/1/2013
• Biomarkers in bipolar disorder: a positional paper from the International Society for Bipolar Disorders Biomarkers Task Force  
  Frey BN, Andreazza AC, Houenou J, Jamain S, Goldstein BI, Frye MA, Leboyer M, Berk M, Malhi GS, Lopez-Jaramillo C, Taylor VH, Dodd S, Frangou S, Hall GB, Fernandes BS,..., Aust N Z J Psychiatry, 1/1/2013
• Baseline thyroid indices and the subsequent response to citalopram treatment, a pilot study  
  Abulseoud O, Gitlin M, Altshuler L, Frye MA, Brain Behav, 1/1/2013
• Paradigm shift: preliminary clinical categorization of ultra-high risk for childhood bipolar disorder to facilitate studies on prevention  
  Post RM, Chang K, Frye MA, J Clin Psychiatry, 1/1/2013
• Can bipolar disorder be viewed as a multi-system inflammatory disease?  
  Leboyer M, Soreca I, Scott J, Frye MA, Henry C, Tamouza R, Kupfer DJ, J Affect Disord, 1/1/2012
• Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder  
  Malhi GS, Bargh DM, McIntyre R, Gitlin M, Frye MA, Bauer M, Berk M, Bipolar Disord, 1/1/2012
• Gender differences in the relationship between depressive symptoms and cravings in alcoholism  
  Boykoff N, Schneekloth TD, Hall-Flavin D, Loukianova L, Karpyak VM, Stevens SR, Biernacka JM, Mrazek DA, Frye MA, Am J Addict, 1/1/2010
• Modafinil for bipolar depression with comorbid methamphetamine abuse  
  Camacho A, Ng B, Frye MA, Am J Addict, 1/1/2010
• Improving the design of maintenance studies for bipolar disorder  
  Gitlin MJ, Abulseoud O, Frye MA, Curr Med Res Opin, 1/1/2010
• Utilization of residential addiction treatment in bipolar disorder  
  Hall-Flavin DK, Schneekloth TD, Loukianova LL, Karpyak VM, Lesnick TG, Biernacka JM, Mrazek DA, Frye MA, Am J Addict, 1/1/2010
• The psychometric validation of the Sheehan Disability Scale (SDS) in patients with bipolar disorder  
  Arbuckle R, Frye MA, Brecher M, Paulsson B, Rajagopalan K, Palmer S, Degl’Innocenti A, Psychiatry Res, 1/1/2009
• The alcohol withdrawal syndrome  
  McKeon A, Frye MA, Delanty N, J Neurol Neurosurg Psychiatry, 1/1/2008
• Diagnostic dilemmas and clinical correlates of mixed states in bipolar depression  
  Frye MA, J Clin Psychiatry, 1/1/2008
• Comorbid substance use disorder in women with bipolar disorder associated with criminal arrest  
  McDermott BE, Quanbeck CD, Frye MA, Bipolar Disord, 1/1/2007
• Modafinil in the treatment of bipolar depression: a placebo, controlled evaluation  
  Frye MA, Grunze H, Suppes T, McElroy SL, Keck PE, Althsuler LL, Leverich GL, Post RM, Am J Psychiatry, 1/1/2007
• Free T4 index and clinical outcome in patients with depression  
  Abulseoud O, Sane N, Cozzolino A, Kiriakos L, Mehra V, Gitlin G, Masseling S, Whybrow P, Altshuler LL, Mintz J, Frye MA, J Affect Discord, 1/1/2007
• Lack of mania prophylaxis associated with lamotrigine monotherapy in manic predominant bipolar I disorder  
  Dossett EC, Land AJ, Gitlin MJ, Frye MA, J Clin Psychiatry, 1/1/2007
• Increased suicidality in mania complicated by alcoholism  
  Fan AH, Frye MA, Masseling SJ, Hwang S, Cozzolino A, Kiriakos L, Mintz J, Sane N, Gitlin MJ, Altshuler L, Psychiatry, 1/1/2007
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Abstracts/Posters

• Association between nicotine dependence, alcohol craving and high-risk situations to relapse in patients with alcohol use disorders
  Hitschfeld M, Schneekloth T, Ebbert J, Hall-Flavin D, Karpyak V, Geske M, Frye M, 167th American Psychiatric Association (APA) Annual Meeting, New York, NY, 1/3/2014
• Impact of smoking cessation on alcohol relapse after residential alcoholism treatment
  Hitschfeld M, Schneekloth T, Ebbert J, Hall-Flavin D, Karpyak V, Geske M, Frye M, 167th American Psychiatric Association (APA) Annual Meeting, New York, NY, 1/3/2014
• Use of a novel adjunctive clinical trial design to examine efficacy, safety of armodafinil for the treatment of bipolar I depression
  Frye MA, New Clinical Drug Evaluation Unit (NCDEU), Hollywood, FL, 1/28/2013
• Double-blind, placebo-controlled, multicenter trial of adjunctive armodafinil for the treatment of major depression associated with bipolar I disorder
  Calabrese J, Frye MA, New Clinical Drug Evaluation Unit (NCDEU), Hollywood, FL, 1/28/2013
• Electroconvulsive therapy use in adolescents at Mayo Clinic: A 20-year practice and outcomes review
  Puffer C, Wall C, Frye MA, American Psychiatric Association (APA), San Francisco, CA, 1/18/2013
• High frequency deep brain stimulation of the lateral habenula potentiates mesoaccumbens dopamine release
  Kim YS, Walker AJ, Abulseoud OA, Lee KH, Frye MA, Tye SJ, Society of Biological Psychiatry 68th Annual Meeting (SOBP), San Francisco, CA, 1/16/2013
• Inverse correlation between glutamate and craving for alcohol
  Frye MA, Hinton DJ, Karpyak VM, Abulseoud OA, Gunderson LJ, Feeder SE, Mrazek DA, Choi D-S, Society of Biological Psychiatry 68th Annual Meeting (SOBP), San Francisco, CA, 1/16/2013
• The phenomenology of high dose social drinking
  McKean AJS, Abulseoud OA, Port JD, Karpyak VM, Choi D-S, Hinton DJ, Gunderson LJ, Frye MA, Society of Biological Psychiatry 68th Annual Meeting (SOBP), San Francisco, CA, 1/16/2013
• Exploratory factor analysis of mixed depression utilizing the young mania rating scale and a modified version of hypomania checklist 32 (mHCL-32)
  Prieto ML, Ozerdem A, Quiroz D, Altinbas K, Aydemir O, Yalin N, Feeder SE, Geske JR, Frye MA, 10th International Conference on Bipolar Disorders (ICBD), Miami, FL, 1/13/2013
• Comorbid cardiovascular disease and bipolar disorder: understanding the phenotype for subsequent inflammatory biomarker study
  Prieto ML, Biernacka JM, McElroy S, Crow J, Chauhan M, Fuentes ME, Choi D-S, Harper KL, Seymour LR, Geske JR, Frye MA, 10th International Conference on Bipolar Disorders (ICBD), Miami, FL, 1/13/2013
• The clinical demographics of the Mayo Clinic bipolar disorder biobank
  Fuentes Salgado M, Kung S, McElroy S, Crow S, Chauhan M, Biernacka J, Seymour, Lisa, Frye MA, 10th International Conference on Bipolar Disorders (ICBD), Miami, FL, 1/13/2013
• Further exploration of the association of SLC6A4 with antidepressant-induced mania
  Biernacka J, Frye MA, 10th International Conference on Bipolar Disorders (ICBD), Miami, FL, 1/13/2013
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Lectures

• Bipolar Disorder: Think Global—Treat Local 
  Medellin, Colombia - 1/22/2014
• Bio-Banking Bipolar Disorder 
  Hanover, NH - 1/20/2014
• Novel Treatment Options for Bipolar Depression 
  Seoul, South Korea - 1/18/2014
• An Evidence Based Approach to Managing Bipolar Manic and Mixed Episodes 
  Newport, RI - 1/16/2014
• Dopamine, Subthalamic Nucleus Deep Brain Stimulation and Parkinson’s Disease: Implications for Mood Disorders; Mania Pre and Post DBS: Implications for Clinical Select... 
  Madrid, Spain - 1/14/2014
• Mayo Clinic Bipolar Biobank: Focus on Metabolic Disorders 
  Madrid, Spain - 1/14/2014
• Ethical Issues Surrounding Neurostimulation in Older Adults; Deep Brain Stimulation Considerations for Parkinson’s Disease Complicated by Mania Secondary to General Me... 
  New York, NY - 1/3/2014
• Biomarkers for Bipolar Depression—The Phenotype and Genotype of Antidepressant-Induced Mania 
  New York, NY - 1/3/2014
• Use of a Novel Adjunctive Clinical Trial Design to Examine Efficacy, Safety of Armodafinil for the Treatment of Major Depressive Episodes Associated With Bipolar I Dis... 
  Hollywood, FL - 1/29/2013
• Pharmacogenomics Targets for Depression and Bipolar Disorder; Bipolar Obesity, Genomic and Clinical Correlates 
  Quito, Ecuador - 1/22/2013
• Individualizing Treatment for Bipolar Depression—The Role of Biobanking and Biomarker Development 
  Cleveland, OH - 1/18/2013
• Inverse Correlation Between Glutamate and Craving for Alcohol 
  San Francisco, CA - 1/16/2013
• Psychiatric Genetics: Phenomics and Genomics and the Prospect of Personalized Medicine—Personalized medicine: 1st Experiences from the Mayo Bipolar Disorder 
  Bucharest, Romania - 1/11/2013
• Can You Distinguish Bipolar and Unipolar Depression?; Potential Biomarkers for Treatment Response in Bipolar Depression 
  Santiago, Chile - 1/1/2013
• NIMH Pathways Seminar 
  Bethesda, MD - 1/28/2012
• Being a Woman With Bipolar Disorder: A Focus on Addiction Comorbidity 
  Istanbul, Turkey - 1/14/2012
• Gender and Addiction / Mood - Implications for Clinical Practice 
  Santiago, Chile - 1/13/2012
• Standard of Care in the United States & Strategies for Preventing Depression in Bipolar Disorder 
  Tokyo, Japan - 1/28/2011
• Pharmacogenomic Targets in Bipolar Disorder 
  Santiago, Chile - 1/11/2011
• Where Are We With the Treatment of Bipolar I Disorder in the Short-Term? 
  Amsterdam, The Netherlands - 1/30/2010
• Pharmacogenomics of Antidepressant-Induced Mania 
  New Orleans, LA - 1/25/2010
• Beyond Maintenance Treatment: Protecting Patients From Destabilization 
  Sao Paulo, Brazil - 1/5/2009
• Bipolar Disorder & Mood Stabilizers—Treatment of Choice for Acute Mania, Bipolar Depression, and Maintenance Phase 
  Girne, Cyprus - 1/1/2009
• Neurobiology of Alcohol Addiction in Patients with Mood and Anxiety Disorders 
  Rochester, MN - 1/30/2008
• Nicotine Dependance and Mood Comorbidity: Approach to Treatment 
  Rochester, MN - 1/29/2008
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