MarkDenisonMD
Pediatric Infectious Disease • Nashville, TNProfessor, Pediatrics, Vanderbilt University School of Medicine
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Office
3601 21st Ave S
Nashville, TN 37232Phone+1 615-322-3000
Summary
- I am the Stahlman Chair and Professor of Pediatrics, and Professor of Pathology, Microbiology & Immunology at Vanderbilt University School of Medicine. I am a Pediatric Infectious Disease Specialist and Perform Research on Emerging Infectious Diseases, Specifically the coronaviruses including SARS-CoV, MERS-CoV, and the novel Coronavirus nCoV-19 / COVID-19 / SARS-CoV-2. I have studied the replication, pathogenesis and evolution of coronaviruses and have developed antivirals against SARS-CoV-2.
Education & Training
University of Iowa Hospitals and ClinicsResidency, Pediatrics, 1980 - 1986
University of Kansas School of MedicineClass of 1980
Certifications & Licensure
TN State Medical License 1991 - 2025
OR State Medical License 2002 - 2002
PA State Medical License 1987 - 1992
IA State Medical License 1980 - 1987- American Board of Pediatrics Pediatrics
- American Board of Pediatrics Pediatric Infectious Diseases
Awards, Honors, & Recognition
- Edward Claiborne Stahlman Chair in Pediatric Physiology and Cell Metabolism Vanderbilt University
- Distinguished Medical Alumnus Kansas University School of Medicine, 2020
- Fellow Association of American Physicians, 2016
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Publications & Presentations
PubMed
- 44 citationsProofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations.Kevin W. Graepel, Xiaotao Lu, James Brett Case, Nicole R. Sexton, Everett Clinton Smith
Mbio. 2017-11-07 - 346 citationsRemdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice.Andrea J. Pruijssers, Amelia S. George, Alexandra Schäfer, Sarah R. Leist, Lisa E. Gralinksi
Cell Reports. 2020-07-21 - 310 citationsCoronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential TherapeuticsEverett Clinton Smith, Hervé Blanc, Marco Vignuzzi, Mark R. Denison
Plos Pathogens. 2013-08-15
Press Mentions
- Dolly Parton Donates Another $1M to Hospital's Children's Disease ResearchJune 16th, 2022
- Dolly Parton Donates $1 Million to Pediatric Infectious Disease Research at Vanderbilt University Medical CenterJune 15th, 2022
- New Covid Pills Offer Hope as Omicron LoomsDecember 7th, 2021
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Grant Support
- Determinants of Coronavirus Replication FidelityNIH, NIAID2013–2023
- Cell Biology of Coronavirus InfectionNIH, NIAIDPresent
- Polymerase Proteins in Coronavirus ReplicationNIH, NIAIDPresent
Professional Memberships
- Fellow
- American Society for VirologyMember
- American Society for MicrobiologyMember
- Pediatric Infectious Diseases SocietyMember
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