MarkDouglasBainMDMS, FAANS

Cerebrovascular Neurosurgery, Neurosurgical Spine Surgery, Skull Base

Staff Department of Neurosurgery/Cerebrovascular Center Director of Cerebrovascular Neurosurgery and Endovascular Surgical NeuroInterventional Radiology Program Program Director Cerebrovascular Neurosurgery Fellowship

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Office
9500 Euclid Ave
Cleveland, OH 44195
Phone+1 216-445-6575

Fax+1 216-636-2061

Summary

I am a board certified neurosurgeon who specializes in Cerebrovascular/Skull Base Neurosurgery as well as Endovascular Surgical Neuroradiology. My primary interests are cerebral aneurysms, AVMs, and moya moya disease.

Education & Training

Emory University School of MedicineFellowship, Cerebrovascular & Skull Base Surgery, 2010 - 2011
Cleveland Clinic FoundationResidency, Neurological Surgery, 2004 - 2010
Cleveland Clinic FoundationFellowship, Neuroendovascular Intervention (Radiology), 2008 - 2009
Georgetown University School of MedicineClass of 2004
Roswell Park Cancer InstituteM.S., Interdisciplinary Sciences, 1998 - 2000

Certifications & Licensure

OH State Medical License 2004 - 2025
PA State Medical License 2012 - 2022
FL State Medical License 2014 - 2017
GA State Medical License 2010 - 2011
American Board of Neurological Surgery Neurological Surgery

Awards, Honors, & Recognition

Faculty Teacher of the Year Cleveland Clinic, 2016
Resident Teacher of the Year Cleveland Clinic Department of Neurosurgery, 2016
Humanitarian Award Cleveland Clinic Department of Neurosurgery, 2007
Department of Neuroscience Award Georgetown University, 2004
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Publications & Presentations

PubMed

51 citations
Mycotic aneurysm detection rates with cerebral angiography in patients with infective endocarditis
Ferdinand K. Hui, Mark Bain, Nancy A. Obuchowski, Steven M. Gordon, Alejandro M Spiotta
Journal of Neurointerventional Surgery. 2015-06-01
18 citations
Dynamic Angiographic Nature of Cerebral Mycotic Aneurysms in Patients With Infective Endocarditis
Seby John, Kevin M. Walsh, Ferdinand K. Hui, Sophia Sundararajan, Scott B. Silverman
Stroke. 2016-01-01
50 citations
Initial Single-Center Technical Experience With the BrainPath System for Acute Intracerebral Hemorrhage Evacuation.
Andrew Bauer, Peter A. Rasmussen, Mark Bain
Operative Neurosurgery. 2016-05-01

Journal Articles

A Tribute to Dr Robert J. White
John Tsiang, Nina Z Moore, Michael P Steinmetz, Min Lang, Mark D Bain, Neurosurgery
The Long-term Effect of Flow Diversion on Large and Giant Aneurysms: An MRI-DSA-Clinical Correlation Study
John S, Bain MD, Hussain MS, Bauer AM, Toth G, World Neurosurg, 1/3/2016
Fenestra Obscura: Flow Diverter Reconstruction of a Complex Vertebrobasilar Aneurysm Through an Obscured Fenestration Limb: Technical Case Report
Toth, Gabor MD; Hui, Ferdinand MD; Bain, Mark MD, Operative Neurosurgery Issue, 1/1/2016
Mycotic aneurysm detection rates with cerebral angiography in patients with infective endocarditis
Hui FK, Bain M, Obuchowski NA, Gordon S, Spiotta AM, Moskowitz S, Toth G, Hussain S, Journal of Neurointerventional Surgery, 1/28/2014
Balloon-augmented Onyx endovascular ligation: initial human experience and comparison with coil ligation
Osanai T, Bain MD, Toth G, Hussain MS, Hui FK, Journal of Neurointerventional Surgery, 1/26/2014
Last resort: case of clot translocation in intra-arterial stroke therapy
John S, Burgess R, Cheng-Ching E, Wisco D, Taqui A, Bain M, Toth G, Uchino K, Hui F, Hussain MS, Neurointerventional Surgery, 1/15/2014
Intra-arterial vasodilator therapy for parainfectious cerebral vasospasm
Taqui A, Koffman L, Hui F, Gomes J, Hussain MS, Bain M, Toth G, Journal Neurol Sci, 1/15/2014
Solitary C1 spinal osteochondroma causing Vertebral artery compression and acute cerebellar infarct
Zhang Y, Ilaslan H, Hussain MS, Bain M, Bauer TW, Skeletal Radiology, 1/1/2014
Addition of hyperacute MRI aids in patient selection, decreasing the use of endovascular stroke therapy
Wisco D, Uchino K, Saqqur M, Gebel JM, Aoki J, Alam S, George P, Newey CR, Man S, Tateishi Y, McNeil J, Winfield M, Cheng-Ching E, Hui FK, Toth G, Bain M, Rasmussen PA..., Stroke, 1/1/2014
Posterior circulation flow diversion: a single-center experience and literature review
Toth G, Bain M, Hussain MS, Moskowitz S, Masaryk T, Rasmussen P, Hui F, Journal Of Neurointerventional Surgery, 1/1/2014
Initial Experience Using the 5MAX™ ACE Reperfusion Catheter in Intra-arterial Therapy for Acute Ischemic Stroke
John S, Hussain MS, Toth G, Bain M, Uchino K, Hui FK, J Cerebrovasc Endovasc Neurosurg, 1/1/2014
Bow hunter's syndrome secondary to bilateral dynamic vertebral artery compression
Healy AT, Lee BS, Walsh K, Bain MD, Krishnaney AA, Journal of Clinical Neuroscience, 1/1/2014
Versatile fill coils: initial experience as framing coils for oblong aneurysms A technical case report
Osanai T, Bain M, Hui F, Interventional Neuroradiology, 1/1/2014
Non-traumatic superior hypophyseal aneurysm with associated pseudoaneurysm presenting with massive epistaxis
Maldonado-Naranjo A, Kshettry VR, Toth G, Bain M, Neurology and Neurosurgery, 1/7/2013
Intraoperative indocyanine green as a substitute for conventional angiography in the surgical management of spinal dural arteriovenous fistulae
Spiotta AM, Bain M, Moskowitz S, Journal Of Neurointerventional Surgery, 1/1/2011
"Double Barrel Stent Reconstruction of a Symptomatic Fusiform Basilar Artery Aneurysm
Bain MD, Hussain MS, Spiotta A, Gonugunta V, Moskowitz S, Gupta R, Neurosurgery, 1/1/2011
Indirect Reperfusion in the setting of Symptomatic Carotid Occlusion by Treatment of Bilateral Vertebral Artery Origin Stenoses
Bain M, Hussain MS, Gonugunta V, Moskowitz S, Hui F, Gupta R, Journal of Stroke and Cerebrovascular Disease, 1/1/2010
Endovascular Treatment of Carotid Embolic Occlusion is Associated with a Higher Rate of Recanalization when Compared to Cardioembolic or Cryptogenic Occlusions
Hussain MS, Lin R, Cheng Ching E, Jovin T, Moskowitz SI, Bain M, Horowitz M, Gonugunta V, Masaryk TJ, Rasmussen PA, Gupta R, Journal of Neurointerventional Surgery, 1/1/2010
Symptomatic Delayed Reocclusion after Initial Successful Revascularization in Acute Ischemic Stroke
Hussain MS, Lin R, Moskowitz S, Bain MD, Gonugunta V, Rasmussen PA, Masaryk TJ, Horowitz MB, Jovin T, Gupta R, Journal of Stroke and Cerebrovascular Disease, 1/1/2010
Initial Experience with Angioplasty of Symptomatic M2 MCA Atheromatous Lesions
Hussain MS, Cheng-Ching E, Bain M, Spiotta AM, Sivapatham T, Hui F, Moskowitz SI, Gupta R, Journal Of Neurointerventional Surgery, 1/1/2010
Symptomatic Delayed Re-Occlusion after Initial Successful Revascularization in Acute Ischemic Stroke
Hussain MS, Lin R, Moskowitz S, Bain M, Gonugunta V, Rasmussen PA, Masaryk TJ, Horowitz MB, Jovin T, Gupta R, Journal of Stroke and Cerebrovascular Disease, 1/1/2010
Successful Recanalization of a Septic Embolus with a Balloon Mounted Stent After Failed Mechanical Thrombectomy
Bain MD, Hussain MS, Gonugunta V, Katzan I, Gupta R, Journal of Neuroimaging, 1/1/2009
Which Patients Benefit from Carotid Stenting? What Recent Trials Show
Bain MD, Moheet AM, Rasmussen P, Cleveland Clinic Journal of Medicine, 1/1/2008
Central role of Interleukin-6-receptor signal transducing chain gp130 in activation of L-selectin adhesion by fever-range thermal stress
Chen Q, Bruce R, Li H, Mulbury MJ, Schleider DM, Bain MD, Wang WC, Baumann H, Evans SS, Immunity, 1/1/2004
Cytokine and adhesion molecule expression in primary human endothelial cells stimulated with fever-range hyperthermia
Shah A, Unger E, Bain MD, Bruce R, Bodkin J, Ginnetti J, Wang WC, Seon B, Stewart CC, Evans SS, Inst. J. Hyperthermia, 1/1/2002
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Abstracts/Posters

Rehemorrhage and Recurrence Rates of Small ACOM Aneurysms post Embolization
Nina Moore, Min Lang, Mark Bain, Journal of Neurosurgery, 1/1/2016
E-033 SOFIA Plus Distal Access Catheter for Acute Stroke Intervention-Initial Single Center Experience
Cerejo, S John, A Bauer, G Toth, M Bain, M Elgabaly, T Masaryk, P Rasmussen, M Hussain, Journal of NeuroInterventional Surgery, 1/1/2016
"Rescue" Intracranial Stenting for Refractory LargeVessel (Re) occlusion in Acute Ischemic Stroke
G Toth, S John, M Elgabaly, M Hussain, M Bain, Journal of NeuroInterventional Surgery, 1/1/2016
Do BMI and Venous Pressure Measurements Predict Need for Revisions in Stenting Pseudotumor Cerebri?
Hui FK, Lystad L, Hussain M, Bain M, Toth G, Kosmorsky G, Rasmussen P, Obuchowski N, Lucaino M, Annual Society of NeuroInterventional Surgery (SNIS), San Francisco, CA, 1/1/2015
Dynamic Septic Embolism Leading to both Vessel Occlusion and Mycotic Aneurysm Formation.
Cheng-Ching E, Walsh K, Toth G, Bain MD, Annual Society of NeuroInterventional Surgery (SNIS), 1/1/2013
Progression of Giant Dysplastic Aneurysms.
Cheng-Ching E, Toth G, Bain MD, Annual Society of NeuroInterventional Surgery (SNIS), 1/1/2013
The Successful Localization of Recipient Bypass Targets Using Selective Microcatheter Intra-arterial Indocyanine Green Videoangiography in the Treatment of a Giant Ant...
Bain, M.D. Moskowitz, S, Spiotta, A, Rasmussen, P, CNS, New Oleans, LA, 1/1/2009
Multi-modality Brain Monitoring following Aneurysmal Subarachnoid Hemorrhage Can Guide Therapy.
Spiotta, A.M., Fuentes, K., Bain, M.D., Lynch, G., Provencio, J.J., Rasmussen, P.A., CNS, Orlando, FL, 1/1/2008
Preclinical Safety Validation of a Stabilized Microinjection Approach for Viral Therapeutics Delivery to the Ventral Horn.
Riley, J., Park, J.J., Federici, T., Bain, M.D., Teng, Q., Franz, C., Bartus, R., Boulis, N.M., CNS, Orlando, FL, 1/1/2008
Central Role of IL-6 in Stimulation of L-Selection Adhesion During Fever-Range Hyperthermia.
Bruce, R.A., Mulbury, M.J., Bain, M.D., Want, W.C., Stewart, C.C., Baumann, H. And Evan, S.S., FASEB J, 1/1/2001
Dynamic Stimulation of L-selection Ligands and ICAM-1 in High Endothelial Venules by Fever-Range Hyperthermia.
Evans, S.S., Shah, A., Unger, E., Bain, M.D., Wang, W.C., Repasky, E.A., FASEB J, 1/1/2001
Central role of IL-6 in stimulation of L-selectin adhesion during fever-range hyperthermia.
Bruce, R.A., Mulbury, M.J., Bain, M.D., Want, W.C., Stewart, C.C., Baumann, H. And Evan, S.S., The II Annual Immunology Program Retreat, State University of New York at Buffalo, Buffalo, NY, 1/15/2000
Fever-like hyperthermia augments lymphocyte delivery to high endothelial venule.
Evan, S.S., Wang, W.C., Burd, R. Bain, M.D., Schleider, D.M., Hanahan, D., and Repasky, E.A., FASEB J, CIS/AAI Annual Meeting, Seattle, WA, 1/12/2000
Fever-range hypethermia stimulates alpha4beta7 integrin-dependent lymphocyte endothelial adhesion.
Bain, M.D., Wang, W.C., Kennedy, B.J., and Evans, S.S., FASEB J, CIS/AAI Annual Meeting, Seattle, WA, 1/12/2000
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Lectures

Minimal Access Surgery for Intracerebral Hemorrhage: Early results and future directions.
1/1/2016
Minimal Access Surgery for Intracerebral Hemorrhage: Early Evidence
1/1/2016
Minimal Access Surgery for Intracerebral Hemorrhage: Early results and future direction.
NY - 1/1/2015
Combined Endovascular and Open Surgical Treatment of Complex Aneurysms.
Shanghai, China - 1/1/2015
Pipeline PseudoLive case demonstration.
1/1/2014
Treatment of bilateral giant carotid aneurysms.
1/1/2014
Carotid Artery Stenting, High Risk Treatment Paradigms.
Chicago, IL - 1/1/2014
Surgical Treatment of Stroke; Hemorrhagic and Ischemic.
Chicago, IL - 1/1/2014
Risks of Surgical and Endovascular Treatment of Mycotic Aneurysms.
1/1/2013
Guidelines for the Management of SAH; Updated AHA Guidelines.
Cleveland, OH - 1/1/2013
Mycotic Aneurysms; Treatment and Review of Literature.
1/1/2012
Blister Intracranial Aneurysms.
1/1/2011
STA/MCA Bypass, Past, Present, and Future Indications
1/1/2010
Review of the Published Evidence on Duty Hours: A Resident's Real World Perspective.
Orlando, FL - 1/1/2008
Dynamic regulation of lymphocyte delivery to high endothelial venules by fever-range hyperthermia.
New Port Beach, CA - 1/8/2002
Dynamic Regulation of Lymphocyte Trafficking: Hot Spots of the Immune Response
San Juan, Puerto Rico - 1/23/2001
Control of Vascular Adhesion by Fever-Range Hyperthermia
San Juan, Puerto Rico - 1/23/2001
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Other

Flow Diversion in the Treatment of Intracranial Aneurysms
Drofa A, Toth G, Rasmussen P, Bain M, Youmans

Press Mentions

Your Healthy Family: 16 Year-Old Making Miraculous Comeback from a Massive StrokeJune 24th, 2021
3D Printing: The New Frontier of Surgery?June 28th, 2019
Intrasaccular Flow Disruption: A Safer, Less-Invasive Approach to Bifurcation Intracranial AneurysmsFebruary 25th, 2019
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