MarcusOthoButlerMD

Oncology • Boston, MA

Medical Oncologist, Princess Margaret Cancer Centre Melanoma/Skin Oncology Site Lead Adoptive Cell Therapy, Tumor Immunotherapy Program

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Office
44 Binney Street
Dana Farber Cancer Institute
Boston, MA 02115
Phone+1 617-632-2334

Fax+1 617-632-3479

Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1996 - 2000
Johns Hopkins UniversityResidency, Internal Medicine, 1992 - 1995
Yale School of MedicineClass of 1992

Certifications & Licensure

MA State Medical License 1995 - 2012

Clinical Trials

Adoptive Transfer of MART1/Melan-A CTL for Malignant Melanoma Start of enrollment: 2007 Aug 01
Completed
Phase 1
Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors
ACTIVE_NOT_RECRUITING
PHASE1
Roles: Contact, Principal Investigator
Adjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation. Start of enrollment: 2022 May 02
Active, not recruiting
Phase 3
Roles: Contact, Principal Investigator
Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination
COMPLETED
Roles: Contact
(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma Start of enrollment: 2023 Jul 03
RECRUITING
PHASE2
Roles: Contact
Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL Start of enrollment: 2023 Jul 26
RECRUITING
PHASE1
Roles: Principal Investigator, Contact
IDE196 (Darovasertib) in Combination with Crizotinib As First-line Therapy in Metastatic Uveal Melanoma Start of enrollment: 2023 Oct 31
RECRUITING
PHASE2, PHASE3
Roles: Contact
Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors Start of enrollment: 2024 Jan 19
RECRUITING
PHASE1
Roles: Contact
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Publications & Presentations

PubMed

Longitudinal Genomic Analysis to Fine-Tune Targeted Therapy: Results of the Phase II LOGIC 2 Trial in Patients With BRAF V600-Mutant Metastatic Melanoma.
Reinhard Dummer, Shahneen Sandhu, Wilson H Miller, Marcus O Butler, Matthew H Taylor
Clinical Cancer Research. 2025-03-19
Randomized, Open-Label, Phase III Study of Tilsotolimod in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced Refractory Melanoma (ILLUMINAT...
Adi Diab, Paolo A Ascierto, Michele Maio, Reham Abdel-Wahab, Sylvie Negrier
Journal of Clinical Oncology. 2025-03-06
Phase 1 study of IMCnyeso, a T cell receptor bispecific ImmTAC targeting NY-ESO-1-expressing malignancies.
Juanita S Lopez, Mohammed Milhem, Marcus O Butler, Fiona Thistlethwaite, Brian A Van Tine
Cell Reports. Medicine. 2025-02-27

Press Mentions

Accuracy of Skin Cancer Diagnosis Varies by Physician, Exam MethodNovember 14th, 2024
Medison Pharma Announces the Approvals by Health Canada and Therapeutics Goods Administration of KIMMTRAK® (Tebentafusp) for the Treatment of Unresectable or Metastatic Uveal MelanomaJune 8th, 2022
Asthma Society’s Pollen Tacker Predicts High Pollen Levels This WeekendJuly 14th, 2020
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Grant Support

Detection Of Immunogenic Ovarian Cancer AntigensNational Cancer Institute2000–2005