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Office
955 Main St.
Buffalo, NY 14209
Summary
- Dr. Halterman is professor of neurology and the senior associate dean for research at the Jacobs School of Medicine and Biomedical Sciences. He received his B.S. in Chemistry from Georgetown University and M.D., Ph.D. from the University of Rochester. After completing his residency at the University of Rochester, he joined the Department of Neurology faculty in 2006. From 2020-2023, Dr. Halterman served as Chair of Neurology at Stony Brook University and Co-Director of the Stony Brook Neurosciences Institute. Work in the Halterman Lab focuses on defining novel therapies for acute stroke and cardiac arrest, neural-immune interactions, and basic mechanisms of reperfusion injury. These studies have received support from the NIH, DoD, and AHA. Dr. Halterman holds patents in the areas of gene transfer and drug discovery.
Education & Training
- University of RochesterResidency, Neurology, 2003 - 2006
- University of RochesterInternship, Internal Medicine, 2002 - 2003
- University of Rochester School of Medicine and DentistryClass of 2002, MD, Distinction in Research
- University of RochesterPh.D., Microbiology & Immunology, 2002
- Georgetown UniversityB.S., Chemistry, 1992
Certifications & Licensure
- NY State Medical License 2005 - 2026
- American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- Nominee, Landis Award for Outstanding Mentorship NINDS, 2018
- Alpha Omega Alpha Medical Honor Society University of Rochester, 2002
- Gilbert B. Forbes Prize in Pediatric Research University of Rochester, 1994
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Publications & Presentations
PubMed
- 147 citationsOncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207)David A. Kooby, John F. Carew, Marc W. Halterman, Jonathan E. Mack, Joseph R. Bertino
FASEB Journal. 1999-08-01 - 72 citationsSelective infection and cytolysis of human head and neck squamous cell carcinoma with sparing of normal mucosa by a cytotoxic herpes simplex virus type 1 (G207).John F. Carew, David A. Kooby, Marc W. Halterman, Howard J. Federoff, Yuman Fong
Human Gene Therapy. 1999-07-01 - 25 citationsThe post-cardiac arrest syndrome: A case for lung-brain coupling and opportunities for neuroprotection.Nguyen Mai, Kathleen Miller-Rhodes, Sara A. Knowlden, Marc W. Halterman
Journal of Cerebral Blood Flow and Metabolism. 2019-03-13
Journal Articles
- Chopper is pro death regardless of the effect of p75ICD on sensitivity to oxidative stressQazi A, Halterman MW, Mi Z., Zhang T. and NF Schor, Oxid Med Cell Longev, 1/1/2011
- The Paradoxof the Neutrophil?s Role in Tissue Injury: A reviewSegelGB, HaltermanMWand MA Lichtman, J Leukocyte Biol, 1/1/2010
- In-tube protocol modification improves transfection rates in murine neuronal culturesHalterman MW, Giuliano R, Schor NF, J Neurosci Meth, 1/1/2009
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Books/Book Chapters
Abstracts/Posters
- Lung redox state modulates neutrophil priming during systemic inflammation.Gates K, Mai N, Prifti L, and Halterman MW, Keystone Symposia on Neuroinflammation: Concepts, Characteristics, Consequences, Keystone, CO, 1/19/2017
- Chronic brain dysfunction driven by acute systemic inflammation. Keystone Symposia on neuroinflammation:Trzeciak A, Lerman Y, Mai N, Halterman M, and Kim M, Concepts, Characteristics, Consequences, Keystone, CO, 1/19/2017
- Systemic immune responses and neutrophil activation in the propagation of neuroinflammation after cerebral ischemia-reperfusionMai N, Prifti L, Halterman MW, Steven R. Schwid Resident and Fellow Research Symposium, Rochester, NY, 1/1/2016
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Lectures
- Targeting immune-mediated cerebral reperfusion injury in the post cardiac arrest syndrome (PCAS)University of Massachusetts, Worchester, MA, 2017; University of Pittsburgh, Pittsburgh, PA, 2017; N - 1/15/2018
- Priming effects of endotoxemia on neutrophil activation, neuroinflammation and reperfusion injury following transient global ischemiaClearwater Beach, FL - 1/30/2017
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Press Mentions
- AHA Grants Will Accelerate Search for New Stroke TherapiesJune 27th, 2018
Grant Support
- Defining Neurotherapeutic Targets In Hypoxia-Induced CHOP-10 Signaling NetworksNational Institute Of Neurological Disorders And Stroke2010–2012
- Targeting Phosphatase Regulated Cleavage Of Hif-1-Alpha In Ischemic Brain InjuryNational Institute Of Neurological Disorders And Stroke2011
- Defining Neurotherapeutic Targets In Hypoxia-Induced CHOP-10 Signaling NetworksNational Institute Of Neurological Disorders And Stroke2008–2009
- Sensing Hypoxia In The CNS Using Herpes VectorsNational Institute Of Mental Health1998–2002
External Links
- Rochester Profilehttps://www.urmc.rochester.edu/people/20663216-marc-w-halterman
- Lab Websitehttps://www.urmc.rochester.edu/labs/neurovascular-protection-group.aspx
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