MaherYounesMD

PubMed

• Erratum: Identification of insulin-like growth factor binding protein-3 as a farnesyl transferase inhibitor SCH66336-induced negative regulator of angiogenesis in head...
  Seung Hyun Oh, Woo-Young Kim, Jai-Hyun Kim, Maher N. Younes, Adel K. El-Naggar
  Clinical Cancer Research. 2019-08-01
• 3 citations
  Erratum: Epidermal Growth Factor Receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyr...
  Bradley A. Schiff, Andrea B. McMurphy, Samar A. Jasser, Maher N. Youne, Dao Doan
  Clinical Cancer Research. 2019-08-01
• 45 citations
  Dual inhibition of epidermal growth factor receptor and insulin-like growth factor receptor I: reduction of angiogenesis and tumor growth in cutaneous squamous cell ca...
  Chad E. Galer, Christina L. Corey, Zhuoying Wang, Maher N. Younes, Fernando Gomez-Rivera
  Head & Neck. 2011-02-01

Abstracts/Posters

• In vivo Imaging of Primary Recurrence and Cervical Lymph Node Metastases in an Orthotopic Nude Mouse Model of Squamous Cell Carcinoma of the Head and Neck.
  Younes MN, Zhou G, Jasser SA, Myers JN, Combined Otolaryngological Spring Meeting, San Diego, CA, 4/26/2007
• Psoriasin/S100A7 modulates b-catenin signaling and inhibits tumor growth and progression of oral cavity squamous cell carcinoma.
  Zhou G, Mandal M, Jasser SA, Zhao M, Yazici YD, Xie T, Younes MN, Kupferman ME, Patel V, Gutkind SJ, EI-Naggar AK, Emberley ED, Watson PH, Bucana CD, Myers JN, 97th Annual American Association for Cancer Research meeting (AACR), Los Angeles, CA, 4/14/2007
• The A12 Antibody To the Insulin-like Growth Factor Receptor-I Inhibits the Growth of Anaplastic Thyroid Carcinoma in an Orthotopic Nude Mouse Model.
  Wang ZY, Kim S, Yazici YD, Younes MN, Jasser SA, Myers JN, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics: Discovery, Biology, and Clinical Applications, Philadelphia, PA, 11/14/2005
• Sorafenib (BAY 43-9006) inhibits the growth and angiogenesis of orthotopic anaplastic thyroid carcinoma xenografts in nude mice.
  Kim S, Yazici YD, Calzada G, Wang ZY, Younes MN, Jasser SA, Myers JN, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics: Discovery, Biology, and Clinical Applications, Philadelphia, PA, 11/14/2005
• Concomitant Inhibition of Epidermal Growth Factor and Vascular Endothelial Growth Factor Receptor Tyrosine Kinases Reduces Growth and Metastasis of Human Salivary Aden...
  Younes MN, Yazici YD, Park YW, Nong X, Jasser SA, El-Naggar AK, Myers JN, 58th Annual Symposium on Cancer Research, Houston, TX, 10/25/2005
• Blockade of Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor Signaling by the Dual Tyrosine Kinase Inhibitor AEE788 and Paclitaxel as T...
  Younes MN, Yigitbasi OG, Park YW, Kim SJ, Jasser SA, Hawthorne VS, Langley RR, Dakak Yazici YD, Mandal M, Bekele BN, Bucana CD, Fidler IJ, Myers JN, 57th Annual Symposium on Fundamental Cancer Research: Signal Transduction: from Pathways to Networks, Combined Otolaryngological Spring Meeting, Houston, TX, 2004; Boca Raton, FL, 2005, 5/13/2005
• Effects of a Novel Inhibitor of STAT3 Signaling on Oral Cavity Squamous Cell Carcinoma Cell Lines.
  Kupferman ME, Mandal M, Younes MN, Zhou G, Xie T, Jasser SA, Priebe W, Myers JN, Combined Otolaryngological Spring Meeting, Boca Raton, FL, 5/13/2005
• AEE788, a dual tyrosine kinase receptor inhibitor, induces endothelial cell apoptosis in human cutaneous squamous cell carcinoma xenografts in nude mice.
  Younes MN, Park YW, Jasser SA, Yigitbasi OG, Zhou G, Bucana CD, Bekele BN, Myers JN, 96th Annual American Association for Cancer Research meeting (AACR), Anaheim, CA, 4/16/2005
• Dual Inhibition of the EGFR and VEGFR Phosphorylation. The role of the new EGFR/VEGFR tyrosine kinase inhibitor NVPAEE788 in Squamous Cell Carcinoma of the Head and Neck.
  Yigitbasi OG, Younes MN, Schiff BA, Doan D, Jasser SA, Myers JN, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, 6th International Conference on Head and Neck Cancer, Boston, MA, 2003; Washington, DC, 2004, 8/7/2004
• Antitumor Activities of Farnesyltransferase Inhibitor (SCH66336) through Induction of Insulin-like Growth Factor Binding Protein-3 in Head and Neck Squamous Cell Carci...
  Oh SH, Kim DK, Kim E, Younes MN, Myers JN, Hong WK, Lee HY, 95th annual American Association for Cancer Research meeting (AACR), Orlando, FL, 3/1/2004
• A Mouse Model for Follicular Thyroid Cancer Induced Bone Lesions.
  Younes MN, Yigitbasi OG, Kim SJ, Doan D, Al-Muhtaseb Z, Jasser SA, Myers JN, IV International Conference on Cancer-Induced bone Diseases, San Antonio, TX, 12/7/2003
• Treatment with NVPAEE788 - A dual inhibitor of EGFR and VEGFR Tyrosine Kinase- Inhibits Anaplastic Thyroid Carcinoma Growth.
  Kim S, Schiff BA, Younes MN, Doan D, Jasser SA, Myers JN, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, MA, 11/17/2003
• The Inhibition of Integrin Linked Kinase by Novel ILK Inhibitors Induces Apoptosis and Restores Anoikis to Squamous Cell Carcinoma of the Head and Neck Cancer Cells.
  Younes MN, Yigitbasi OG, Jasser SA, Doan D, Schiff BA, El-Naggar A, Mills GB, Myers JN, 94th Annual American Association for Cancer Research meeting (AACR), Washington, DC, 7/1/2003
• Integrin Linked Kinase (ILK) is Overexpressed and ILK Inhibition Leads to Growth Inhibition of Anaplastic and Papillary Thyroid Cancer Cells.
  Younes MN, Yigitbasi OG, Jasser SA, Doan D, El-Naggar A, Mills GB, Myers JN, Combined Otolaryngological Spring Meeting, Nashville, TN, 5/1/2003
• The effect of the EGF-R inhibitor ZD 1839 (Iressa) on Thyroid Cancer.
  Schiff BA, Jasser SA, Doan D, Yeung SC, Younes MN, McMurphy A, Holsinger FC, El-Naggar A, Sherman SI, Myers JN, Combined Otolaryngological Spring Meeting, Nashville, TN, 5/1/2003
• An Orthotopic Nude Mouse Model of Thyroid Cancer.
  Schiff BA, Younes MN, Jasser SA, Doan D, Yeung SC, Holsinger FC, Myers JN, 94th Annual American Association for Cancer Research meeting (AACR) meeting, 44th Clinical Conference on Molecular Therapeutics for Cancer Metastasis, Houston, TX, 3/1/2003
• AKT as a potential therapeutic target for head and neck cancer.
  Younes MN, Swan EA, Mandal M, Jasser SA, Doan D, Mills GB, Myers JN, 44th Clinical Conference on Molecular Therapeutics for Cancer Metastasis, Houston, TX, 3/1/2003
• Dephosphorylation and down regulation of Akt is associated with farnesyltransferase inhibitor (SCH66336) treatment in head and neck squamous cell carcinoma cell lines.
  Hassan KA, Wu W, Wang L, Lee HY, Younes MN, Hee Jun K, Lotan R, Kim E, Kies MS, Bishop R, Kirschmeier P, Hong WK, Mao L, Khuri FR, 93rd Annual American Association for Cancer Research (AACR) Meeting, San Francisco, CA, 4/6/2002
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Lectures

• Dual EGFR and VEGFR Inhibition with NVP-AEE788 for the Treatment of Aggressive Follicular Thyroid Cancer. 
  Chicago, IL - 8/1/2006
• Molecular Targeted Therapy in Follicular Thyroid Cancer. 
  Houston, TX - 9/16/2005

Other

• Melanoma. 
  Younes MN, Myers JN, Multidisciplinary Care of Head and Neck Cancer. Web Book, 2nd Edition
  http://headneckcancer.bcdecker.com/
  1/1/2005