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Maciej Lesniak, MD, Neurosurgery, Chicago, IL

MaciejSLesniakMD

Neurosurgery Chicago, IL

Brain & Spinal Tumor, Cerebrovascular Neurosurgery, Skull Base

Professor and Chairman, Department of Neurological Surgery, Northwestern University Feinberg School of Medicine

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  • Office

    Northwestern University Feinberg School of Medicine
    676 N St Clair, Suite 2210
    Chicago, IL 60611
    Phone+1 312-695-0110

Education & Training

  • Harvard School of Public Health
    Harvard School of Public HealthM.S., Health Care Management, 2008 - 2010
  • Johns Hopkins University
    Johns Hopkins UniversityResidency, Neurological Surgery, 1997 - 2003
  • Johns Hopkins University School of Medicine
    Johns Hopkins University School of MedicineInternship, Transitional Year, 1996 - 1997
  • Johns Hopkins University School of Medicine
    Johns Hopkins University School of MedicineClass of 1996
  • Harvard University
    Harvard UniversityB.A., Magna Cum Laude, 1988 - 1992

Certifications & Licensure

  • FL State Medical License
    FL State Medical License 2024 - Present
  • IL State Medical License
    IL State Medical License 2003 - 2026
  • MD State Medical License
    MD State Medical License 2002 - 2026
  • MA State Medical License
    MA State Medical License 2008 - 2025
  • American Board of Neurological Surgery Neurological Surgery

Awards, Honors, & Recognition

  • Outstanding Investigator Award The National Institutes of Health, 2015
  • Alumni Award for Excellence in Medicine St. Ignatius College Prep, 2013
  • John D. Arnold Mentor Award for Sustained Excellence Mentoring Medical Students University of Chicago, 2013
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Tamoxifen Overrides Autophagy Inhibition in Beclin-1-Deficient Glioma Cells and Their Resistance to Adenovirus-Mediated Oncolysis via Upregulation of PUMA and BAX  
    Maciej Lesniak, MD, Nature
  • Hitting a moving target: glioma stem cells demand new approaches in glioblastoma therapy  
    Spencer DA, Auffinger BM, Murphy JP, Muroski ME, Qiao J, Gorind Y, Lesniak MS, Current Cancer Drug Targets, 1/15/2016
  • Dynamic in vivo SPECT imaging of neural stem cells functionalized with radiolabeled nanoparticles for tracking of glioblastoma  
    Cheng SH, Yu D, Tsai HM, Morshed RA, Kanojia DA, Lo LW, Govind Y, Zhang L, Aboody KS, Lesniak MS, Chen CT, and Balyasnikova IV, J Nuc Med, 1/1/2016
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Books/Book Chapters

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Abstracts/Posters

  • Gross-total resection and adjuvant radiation most significant predicators of improved survival in atypical meningioma
    Rydzewski NR, Lesniak MS, Chandler JP, Tate MC, Sachdev S, American Society for Radiation Oncology 58th Annuyal Meeting, San Diego, CA, 1/27/2017
  • Clinical and molecular differences between African-American and Caucasian glioma patients
    Wu M, Horbinski C, Chang AL, Ahmed AU, Balyasnikova IV, Chandler JP, and Lesniak MS, The Fifteenth Asia Pacific Bioinformatics Conference, Shenzhen, China, 1/18/2017
  • Intranasal delivery of mesenchymal stem cells targets diffuse intrinsic pontine glioma in mouse model
    Chastofsky M, Procissi D, Yang C, Goldman S, Lesniak MS, Hashizume R, and Balyasnikova IV, World Federation of Neuro-Oncology Meeting, Zurich, Switzerland, 1/7/2017
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Lectures

  • Brain Metastases: The Forgotten Entity or the Future of Hope 
    Chicago, IL - 1/3/2017
  • Stem cells as delivery vehicles in neuro-oncology 
    Washington, DC - 1/6/2015
  • Stem cell carriers for oncolytic virotherapy of glioma 
    Washington, DC - 1/24/2014
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Other

Press Mentions

  • New Glioblastoma Treatment Reaches Human Brain Tumor and Helps Immune Cells Recognize Cancer Cells
    New Glioblastoma Treatment Reaches Human Brain Tumor and Helps Immune Cells Recognize Cancer CellsJune 6th, 2024
  • Northwestern Selected as Home for Journal of Clinical Investigation; McNally to Serve as Editor-in-Chief
    Northwestern Selected as Home for Journal of Clinical Investigation; McNally to Serve as Editor-in-ChiefDecember 14th, 2021
  • Northwestern’s SPORE Has Made Advances in Understanding the Genetic Basis of Glioblastoma
    Northwestern’s SPORE Has Made Advances in Understanding the Genetic Basis of GlioblastomaOctober 3rd, 2021
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Grant Support

  • Magnetic-Vortex Microdiscs For Glioma TherapyNational Institute Of Neurological Disorders And Stroke2012
  • Regulatory T Cells In Malignant GliomaNational Cancer Institute2009–2012
  • Conditionally Replicative Adenoviral Vectors For Malignant GliomaNational Cancer Institute2008–2012
  • Neural Stem Cell Based Virotherapy For Malignant GliomaNational Institute Of Neurological Disorders And Stroke2010–2011
  • Development Of An Adenoviral Vector With Chimeric Fiber For Malignant GliomaNational Cancer Institute2008–2009
  • Targeted Adenoviral Gene Therapy For Malignant GliomaNational Institute Of Neurological Disorders And Stroke2005–2009

Professional Memberships

Other Languages

  • Polish, Spanish