LukeRussellSmartMD

Clotting Disorder, Hemophilia & Bleeding Disorder, Sickle Cell & Other Anemias

Assistant Professor of Medicine & Pediatrics

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Dr. Luke Smart, MD, is a double boarded, pediatric and adult hematologist based in Cincinnati, OH, with expertise in classical hematology, particularly sickle cell disease. An alumnus of University of Maryland School of Medicine, his postgraduate education included a combined Internal Medicine/Pediatrics residency followed by fellowships in Global Health, Medical Hematology, and Pediatric Hematology/Oncology. Currently, he is an Assistant Professor Medicine & Pediatrics at the University of Cincinnati College of Medicine and sees patients at both Cincinnati Children's Hospital Medical Center and University of Cincinnati Medical Center. His research focuses on improving the health of people living with sickle cell disease in low-resource, especially in sub-Saharan Africa, where he has conducted several clinical trials.

University of Cincinnati Medical Center/College of MedicineFellowship, Hematology and Medical Oncology, 2016 - 2020
Cincinnati Children's Hospital Medical CenterFellowship, Pediatric Hematology/Oncology, 2016 - 2020
New York Presbyterian HospitalFellowship, Global Health, 2012 - 2016
University of Rochester Medical CenterResidency, Internal Medicine/Pediatrics, 2008 - 2012
University of Maryland School of MedicineClass of 2008

ASH Research Training Award for Fellows American Society of Hematology
Strauss Fellowship for Global Health Cincinnati Children's Research Foundation
Thrasher Research Fund Early Career Award Thrasher Research Fund
ASH Abstract Achievement Award American Society of Hematology, 2017, 2019
ASPHO Early Career Travel Stipend Award American Society of Pediatric Hematology Oncology, 2018
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PubMed

Validation of Pediatric Self-Report Pain Scales in Sub-Saharan Africa: A Systematic Review.
Stephen Rineer, Derek Kwakye, Emmanuela E Ambrose, Iii Don P Jason, Luke R Smart
Journal of Pain and Symptom Management. 2025-02-01
Hydroxyurea for Children and Adults with Hemoglobin SC Disease.
Yvonne A Dei-Adomakoh, Catherine I Segbefia, Teresa S Latham, Adam C Lane, Klenam Dzefi-Tettey
NEJM Evidence. 2025-02-01
Causes and Consequences of Persistent Anemia after 6 Months of Antiretroviral Therapy in Tanzania: An Observational Comparative Cohort Study.
Duncan K Hau, Salama Fadhil, Myung Hee Lee, Bernard Desderius, Megan Willkens
The American Journal of Tropical Medicine and Hygiene. 2025-01-08

Lectures

Genetic Analysis in the Tanzania Sickle Surveillance Study (TS3): Modifiers of Sickle Cell Disease and Identification of Hemoglobin Variants
61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019

Surveillance for Sickle Cell Disease, United Republic of TanzaniaSeptember 28th, 2020
Cincinnati Children's Helping to Eliminate Sickle Cell SymptomsJune 25th, 2019

Sickle Cell Anemia, Splenic Pathology, and Hydroxyurea in Sub-Saharan AfricaNHLBI2020–2025
Strauss Fellowship for Global HealthCincinnati Children's Research Foundation2019–2020
Research Training Award for FellowsAmerican Society of Hematology2019–2020
Early Career AwardThrasher Research Fund2018–2020