Luigi Notarangelo MD
Professor of Pediatrics, Boston Children's Hospital
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10 Center Drive - NIHBuilding 10, Room 5-3950Bethesda, MD 20892
Phone+1 301-761-7550
Fax+1 301-402-2240
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Education & Training
University of Pavia Faculty of MedicineClass of 1980
Certifications & Licensure
MD State Medical License 2016 - 2025
MA State Medical License 2009 - 2018
Clinical Trials
- Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector Start of enrollment: 2010 Apr 01
- Patients Treated for Chronic Granulomatous Disease (CGD) Since 1995 Start of enrollment: 2014 Jun 01
- The Mechanistic Biology of Primary Immunodeficiency Disorders Start of enrollment: 2018 May 30
Publications & Presentations
PubMed
- Reconstitution of Norovirus-Specific T-Cell Responses Following Hematopoietic Stem Cell Transplantation in Patients With Inborn Errors of Immunity and Chronic Noroviru...Jessica Durkee-Shock, Ariella Cohen, Naseem Maghzian, Gloria Pezzella, Mariah Jensen-Wachspress
The Journal of Infectious Diseases. 2025-03-17 - Prior SARS-CoV-2 infection affects adaptive immune responses to Omicron BA.4/BA.5 mRNA booster.Brianna T Wachter, Qin Xu, Lihong Shi, Peter D Burbelo, Kathy Myint-Hpu
The Journal of Allergy and Clinical Immunology. 2025-03-03 - Learning from Inborn Errors of Immunity: From mechanisms to translation.Mohamed-Ridha Barbouche, Luigi D Notarangelo
Seminars in Immunology. 2025-03-01
Journal Articles
- T Cell Dynamics and Response of the Microbiota After Gene Therapy to Treat X-linked Severe Combined ImmunodeficiencyLuigi D Notarangelo, Judith Kelsen, Ronald G Collman, Donald B Kohn, BioMed Central
- HPV: CIB1 Is for EVER and EVERLuigi Notarangelo, MD, The Journal of Experimental Medicine
- T Cell Defects in Patients with ARPC1B Germline Mutations Account for Their Combined ImmunodeficiencyLuigi Notarangelo, MD, Blood
Abstracts/Posters
- Outcome of Hematopoietic Stem Cell Gene Therapy for Wiskott-Aldrich SyndromeLuigi Notarangelo, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Characterizing Autoimmune Hemolytic Anemia in RAG DeficiencyLuigi Notarangelo, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Enhanced Transduction Lentivector Gene Therapy for Treatment of Older Patients with X-Linked Severe Combined ImmunodeficiencyLuigi Notarangelo, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Lectures
- Primary Immunodefiencies for the Hematologist: Finding the Needle in the Haystack61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
Other
- Human iPSC-Derived Trigeminal Neurons Lack Constitutive TLR3-Dependent Immunity That Protects Cortical Neurons from HSV-1 InfectionLuigi Notarangelo, MD, Proceedings of the National Academy of Sciences
https://www.doximity.com/articles/d9628f81-5e13-4f24-a08f-34117c0cec02
UpToDate, Wolters Kluwer Health - 2013-04-02
Authored Content
- Cord Blood Banking for Potential Future TransplantationOctober 2017
Press Mentions
US Health Experts Warn About Giving Coronavirus Jabs to ChildrenNovember 13th, 2020- 5 Takeaways from the FDA's Closely Watched Coronavirus Vaccine MeetingOctober 24th, 2020
- FDA’s COVID-19 Vaccine Adcomm Raises Questions as First Readouts LoomOctober 23rd, 2020
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Grant Support
- Characterization of the cellular and molecular bases of inborn errors of immunityNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESPresent
- Characterization of the cellular and molecular bases of inborn errors of immunityNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESPresent
- Characterization of host immune responses to SARS-CoV-2NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESPresent
- Characterization of host immune responses to SARS-CoV-2NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESPresent
Professional Memberships
- Member
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