LucasWongMD

Hematologic Oncology

Oncologist Baylor Scott & White Health Principal Investigator, Community Clinical Oncology Program Co-Director, Gastrointestinal Cancer Program

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Office
2401 S 31st St
Temple, TX 76508
Phone+1 254-724-2111
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Education & Training

University of Arizona College of Medicine-TucsonFellowship, Hematology and Medical Oncology, 1991 - 1994
University of North Carolina HospitalsResidency, Internal Medicine, 1988 - 1991
The University of Texas Health Science Center at San AntonioClass of 1988

Certifications & Licensure

AZ State Medical License 1995 - 2025
CA State Medical License 2000 - 2025
NC State Medical License 1990 - 2024
TX State Medical License 1994 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Fellow (FACP) American College of Physicians, 2003

Clinical Trials

Pentostatin, Cyclophosphamide, and Rituximab Followed By Campath-1H in Patients With Relapsed or Refractory B-Cell CLL Start of enrollment: 2005 Apr 14
Completed
Phase 2
Mindfulness Relaxation Compared With Relaxing Music and Standard Symptom Management Education in Treating Patients Who Are Undergoing Chemotherapy For Newly Diagnosed Solid Tumors Start of enrollment: 2004 Jun 01
Completed
Not Applicable
Study of Bavituximab in Patients With Advanced Solid Tumor Malignancies Start of enrollment: 2005 Jun 01
Completed
Phase 1
Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Start of enrollment: 2005 Nov 01
Completed
Phase 3
Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery Start of enrollment: 2007 Jun 01
Active, not recruiting
Phase 3
Thyroid Dysfunction in Women With Newly Diagnosed Breast Cancer Compared to Healthy Volunteers Start of enrollment: 2006 Apr 01
Completed
Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer Start of enrollment: 2006 Sep 15
Completed
Phase 2
S0500 Treatment Decision Making Based on Blood Levels of Tumor Cells for Metastatic Breast Cancer Treated With Chemo Start of enrollment: 2006 Oct 01
Completed
Phase 3
Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma Start of enrollment: 2008 Feb 29
Active, not recruiting
Phase 3
Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery Start of enrollment: 2008 Oct 01
Completed
Phase 1
Sunitinib Malate as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination Chemotherapy Start of enrollment: 2008 Jun 15
Completed
Phase 3
Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy Start of enrollment: 2008 Nov 10
Active, not recruiting
Phase 3
S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer Start of enrollment: 2009 May 01
Completed
Phase 2
S0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone Metastases Start of enrollment: 2008 Dec 01
Completed
S0819: Carboplatin and Paclitaxel With or Without Bevacizumab and/or Cetuximab in Treating Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer Start of enrollment: 2009 Jul 15
Terminated
Phase 3
Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy Start of enrollment: 2011 Jan 18
Completed
Phase 2
S0931, Everolimus in Treating Patients With Kidney Cancer Who Have Undergone Surgery Start of enrollment: 2011 Apr 01
Active, not recruiting
Phase 3
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery Start of enrollment: 2010 Jun 01
Active, not recruiting
Phase 3
Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer Start of enrollment: 2011 May 16
Completed
Not Applicable
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Start of enrollment: 2011 Jan 15
Active, not recruiting
Phase 3
Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery Start of enrollment: 2011 May 25
Active, not recruiting
Phase 3
Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer Start of enrollment: 2011 Jan 06
Active, not recruiting
Phase 3
S1014 Abiraterone Acetate in Treating Patients With Prostate Cancer Who Have Undergone Initial Hormone Therapy Start of enrollment: 2011 Aug 09
Active, not recruiting
Phase 2
PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery Start of enrollment: 2012 Jun 12
Active, not recruiting
Phase 2, Phase 3
Study of Ibrutinib vs Placebo, in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma (RESOLVE) Start of enrollment: 2015 May 01
Completed
Phase 3
A Study of Ramucirumab (LY3009806) in Combination With Paclitaxel in Participants With Gastric Cancer Start of enrollment: 2015 Oct 12
Completed
Phase 2
Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced Pancreatic Cancer Start of enrollment: 2019 May 10
Active, not recruiting
Phase 3
Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study Start of enrollment: 2019 Nov 22
Recruiting
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Pembrolizumab Plus Binimetinib With or Without Chemotherapy for MSS/pMMR Metastatic Colorectal Cancer: Outcomes From KEYNOTE-651 Cohorts A, C, and E.
Eric X Chen, Petr Kavan, Mustapha Tehfe, Michael B Sawyer, E Gabriela Chiorean, Chenxiang Li, Pierre Leconte, David Adelberg, Richard Kim, Jeremy S Kortmansky, Christo...> ;Clinical Colorectal Cancer. 2024 Jun 1
Pembrolizumab Plus mFOLFOX7 or FOLFIRI for Microsatellite Stable/Mismatch Repair-Proficient Metastatic Colorectal Cancer: KEYNOTE-651 Cohorts B and D.
Mustapha Tehfe, Petr Kavan, Eric X Chen, Qing Zhao, Raluca Predoiu, Chenxiang Li, Pierre Leconte, E Gabriela Chiorean, Richard Kim, Jorge Chaves, Jeremy S Kortmansky, ...> ;Clinical Colorectal Cancer. 2024 Jun 1
Improved Pathologic response to chemoradiation in MGMT methylated locally advanced rectal cancer.
Garrett L Jensen, Niloufar Pourfarrokh, Marcus Volz, Linden L Morales, Kimberly Walker, Kendall P Hammonds, Moataz El-Ghamry, Lucas Wong, Parsa Hodjat, Eduardo Castro,...> ;Clinical and Translational Radiation Oncology. 2023 Sep 1
1 citations
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone provokes progression from chronic pancreatitis to pancreatic intraepithelial neoplasia.
Xin Chen, Liang Sheng, Jiguang Ma, Dan Qi, Xuqi Li, Zheng Wang, Zheng Wu, Lucas Wong, Jason H Huang, Erxi Wu, Qingyong Ma, Dong Zhang> ;Iscience. 2022 Jan 21
24 citations
NAF-1 Inhibition by Resveratrol Suppresses Cancer Stem Cell-Like Properties and the Invasion of Pancreatic Cancer.
Tao Qin, Liang Cheng, Ying Xiao, Weikun Qian, Jie Li, Zheng Wu, Zheng Wang, Qinhong Xu, Wanxing Duan, Lucas Wong, Erxi Wu, Qingyong Ma, Jiguang Ma> ;Frontiers in Oncology. 2020 Jul 16
14 citations
A randomized trial of nurse-administered behavioral interventions to manage anticipatory nausea and vomiting in chemotherapy.
Jonathan Hunter, Robert G. Maunder, Dawen Sui, Mary Jane Esplen, Alejandro Chaoul, Michael J. Fisch, Roland L. Bassett, Marlys M. Harden-Harrison, Lore W. Lagrone, Luc...> ;Cancer Medicine. 2020 Jan 19
3 citations
Prognostic factors and hazard ratios in colorectal cancer patients over 80 years of age: a retrospective, 20-year, single institution review.
Saira Shervani, Gary Lu, Kristen Sager, Takeshi Wajima, Lucas Wong> ;Journal of Gastrointestinal Oncology. 2018 Mar 26
11 citations
Phase II study of olaratumab with paclitaxel/carboplatin (P/C) or P/C alone in previously untreated advanced NSCLC
David E. Gerber, Paul Swanson, Ariel Lopez-Chavez, Lucas Wong, Afshin Dowlati, Nathan A. Pennell, Damien M. Cronier, Amy Qin, Robert Ilaria, Jan Cosaert, Ashwin Shahir...> ;Lung Cancer. 2017 Sep 1
3 citations
Bile duct lymphoma disguised as cholangiocarcinoma.
Charis G Durham, Deepna Jaiswal, Lucas Wong> ;Proceedings. 2017 Apr 1
3 citations
High- versus low-dose leucovorin in the modified FOLFOX6 regimen for first-line treatment of metastatic colorectal cancer:
Jana Reynolds, April Chamberland-Tremblay, Jon D. Herrington, Yolanda Munoz Maldonado, Lucas Wong> ;Journal of Oncology Pharmacy Practice. 2017 Apr 1
5 citations
Randomized trial of medroxyprogesterone acetate for the prevention of endometrial pathology from adjuvant tamoxifen for breast cancer: SWOG S9630.
Ronald K. Potkul, Joseph M. Unger, Robert B. Livingston, Katherine D. Crew, Sharon P. Wilczynski, Caryl G. Salomon, Barbara L. Smith, Lucas Wong, David L. Campbell, Da...> ;NPJ Breast Cancer. 2016 Aug 10
56 citations
Inhibition of Mast Cell-Derived Histamine Decreases Human Cholangiocarcinoma Growth and Differentiation via c-Kit/Stem Cell Factor-Dependent Signaling.
Victoria Huynh, Laura Hargrove, Lindsey Kennedy, Allyson Graf-Eaton, Jennifer Owens, Jerome P. Trzeciakowski, Kyle Hodges, Sharon DeMorrow, Yuyan Han, Lucas Wong, Gian...> ;The American Journal of Pathology. 2016 Jan 1
6 citations
A Phase 2 Randomized, Double-Blind, Multicenter Trial of Imexon Plus Gemcitabine Versus Gemcitabine Plus Placebo in Patients With Metastatic Chemotherapy-naïve Pancrea...
Steven J. Cohen, Mark M. Zalupski, Paul Conkling, Francis W. Nugent, Wen Wee Ma, Manuel Modiano, Rolan Pascual, Fa-Chyi Lee, Lucas Wong, Evan M. Hersh> ;American Journal of Clinical Oncology. 2015 Dec 24
Mortality by treatment in patients ≥80 years of age with gastroesophageal cancer seen in a 20-year period at a single medical center.
Tara Barnett, James Mason, Yolanda Munoz Maldonado, Lucas Wong> ;Proceedings. 2015 Jul 1
13 citations
A phase II, randomized, double blind trial of calcium aluminosilicate clay versus placebo for the prevention of diarrhea in patients with metastatic colorectal cancer ...
Bryan K. Kee, Jeffrey S. Morris, Rebecca Slack, Todd Crocenzi, Lucas Wong, Ben Esparaz, Michael J. Overman, Katrina Y. Glover, Desiree Jones, Sijin Wen, Michael J. Fisch> ;Supportive Care in Cancer. 2015 Jan 1
A phase II study of docetaxel and vinorelbine plus filgrastim for HER-2 negative, stage IV breast cancer: SWOG S0102
Julie R. Gralow, William E. Barlow, Danika Lew, Kim Z Dammann, George Somlo, Kristine Rinn, Stanley Vogel, Lucas Wong, Robert B. Livingston, Gabriel N. Hortobagyi> ;Breast Cancer Research and Treatment. 2014 Jan 1
71 citations
Phase 2, multicenter, open-label study of tigatuzumab (CS-1008), a humanized monoclonal antibody targeting death receptor 5, in combination with gemcitabine in chemoth...
Andres Forero-Torres, Jeffrey R. Infante, David M. Waterhouse, Lucas Wong, Selwyn M. Vickers, Edward Arrowsmith, Aiwu Ruth He, Lowell L. Hart, D. Trent, JamesH. Wade, ...> ;Cancer Medicine. 2013 Dec 1
42 citations
Engineering a CD123xCD3 bispecific scFv immunofusion for the treatment of leukemia and elimination of leukemia stem cells
Shu-Ru Kuo, Lucas Wong, Jen Sing Liu> ;Protein Engineering, Design & Selection. 2012 Oct 1
55 citations
Phase I Safety and Pharmacokinetic Study of Bavituximab, a Chimeric Phosphatidylserine-Targeting Monoclonal Antibody, in Patients with Advanced Solid Tumors
David E. Gerber, Alison Stopeck, Lucas Wong, Lee S. Rosen, Philip E. Thorpe, Joseph Shan, Nuhad K. Ibrahim> ;Clinical Cancer Research. 2011 Nov 1
56 citations
Phase II trial of romidepsin (NSC-630176) in previously treated colorectal cancer patients with advanced disease: a Southwest Oncology Group study (S0336).
Robert P. Whitehead, Cathryn Rankin, Paulo M. Hoff, Philip J. Gold, Kevin G. Billingsley, Robert Chapman, Lucas Wong, John H. Ward, James L. Abbruzzese, Charles D. Blanke> ;Investigational New Drugs. 2009 Oct 1
25 citations
Caspase-mediated Cleavage of β-Catenin Precedes Drug-induced Apoptosis in Resistant Cancer Cells
Subramanian Senthivinayagam, Prajna Mishra, Suresh Kanna Paramasivam, Srinivas Yallapragada, Malay Chatterjee, Lucas Wong, Ajay Rana, Basabi Rana> ;The Journal of Biological Chemistry. 2009 May 15
458 citations
Safety and Efficacy of Oxaliplatin and Fluoropyrimidine Regimens With or Without Bevacizumab As First-Line Treatment of Metastatic Colorectal Cancer: Results of the TR...
Howard S. Hochster, Lowell L. Hart, Ramesh K. Ramanathan, Barrett H. Childs, John D. Hainsworth, Allen Lee Cohn, Lucas Wong, Louis Fehrenbacher, Yousif A. Abubakr, M. ...> ;Journal of Clinical Oncology. 2008 Jul 20
61 citations
Glycogen Synthase Kinase-3β Induces Neuronal Cell Death via Direct Phosphorylation of Mixed Lineage Kinase 3
Rajakishore Mishra, Manoj K. Barthwal, Gautam Sondarva, Basabi Rana, Lucas Wong, Malay Chatterjee, James R. Woodgett, Ajay Rana> ;The Journal of Biological Chemistry. 2007 Oct 19
24 citations
Tumor lysis syndrome after bortezomib therapy for plasma cell leukemia.
Adam D Jaskiewicz, John D Herrington, Lucas Wong> ;Pharmacotherapy. 2005 Dec 1
18 citations
Toxin conjugate therapy of cancer.
Lucas Wong, Dick Y. Suh, Arthur E. Frankel> ;Seminars in Oncology. 2005 Dec 1
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Abstracts/Posters

Characteristics of Inferior Vena Cava Filter Placement, Management, and Retrieval at a Multi-Center Institution
Lucas Wong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019