LoutfiSAboussouanMD

PubMed

• Timing of Noninvasive Ventilation Initiation for Chronic Hypercapnic Respiratory Failure of COPD.
  Umur Hatipoğlu, Jason Dean, Loutfi S Aboussouan
  American Journal of Respiratory and Critical Care Medicine. 2024-10-15
• Perioperative Management in Neuromuscular Diseases: A Narrative Review.
  Aparna Bhat, Jason Dean, Loutfi S Aboussouan
  Journal of Clinical Medicine. 2024-05-17
• The quest for accurate evaluation and treatment of sleep disordered breathing in spinal cord injury.
  Loutfi S Aboussouan, M Safwan Badr, Abdulghani Sankari
  Sleep. 2023-12-11

Journal Articles

• Sleep in amyotrophic lateral sclerosis  
  Aboussouan LS, Mireles-Cabodevila E, Curr Sleep Med Rep, 1/1/2017
• Acute exacerbation of COPD: A narrative review for the internist  
  Hatipoglu U, Aboussouan LS, Cleve Clin J Med, 1/1/2016
• Postoperative complications in patients with unrecognized obesity hypoventilation syndrome undergoing elective non-cardiac surgery  
  Kaw R, Bhateja P, Paz-y-Mar H, Hernandez AV, Ramaswamy A, Deshpande A, Aboussouan LS, Chest, 1/1/2016
• Characteristics of alpha-1 antitrypsin–deficient individuals in the Long-term Oxygen Treatment Trial and comparison with other subjects with chronic obstructive pulmon...  
  Stoller JK, Aboussouan LS, Kanner RE, Wilson LA. Diaz P, Wise R, Ann Am Thorac Soc, 1/1/2015
• Obesity hypoventilation syndrome and anesthesia considerations  
  Kaw R, Argalious M, Aboussouan LS, Chung F, Sleep Med Clin, 9/2014
• Determinants of Nocturnal Hypercapnia in Sleep apnea  
  Jaimchariyatam N, Dweik R, Kaw R, Aboussouan LS, J Clin Sleep Med, 1/1/2013
• Long Term Continuous Positive Airway Pressure Therapy Normalizes High Exhaled Nitric Oxide (FENO) levels in Obstructive Sleep Apnea  
  Chua A-P, Aboussouan LS, Minai OA, Paschke K, Laskowski D, Dweik RA, J Clin Sleep Med, 1/1/2013
• COPD pharmacotherapy  
  Hatipoglu U, Aboussouan LS, JCOM, 1/1/2012
• Sleep Sleep Quality, Depression, and Quality of Life in Patients with Pulmonary Hypertension  
  Batal O, Khatib OF, Bair N, Aboussouan LS, Minai OA, Lung, 1/1/2011
• Non-invasive Positive Pressure Ventilation for Stable Outpatients: CPAP and beyond  
  Theerakorn T, Ricaurte B, Aboussouan LS, Cleve Clin J Med, 1/1/2010
• Noninvasive Positive Pressure Ventilation in Acute Settings  
  Aboussouan LS, Ricaurte B, Cleve Clin J Med, 1/1/2010
• Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma A multicenter, randomized, double-blind, sham-controlled clinical trial  
  Castro, M, Rubin AS, Laviolette M, Fiterman J, et al. (listed as Cleveland Clinic Co-investigator), Am J Respir Crit Care Med, 1/1/2010
• Mechanisms of exercise limitation and pulmonary rehabilitation for patients with neuromuscular disease  
  Aboussouan LS, Chronic Respiratory Disease, 1/1/2009
• Determinants of hypercapnia in obese patients with obstructive sleep apnea: a systematic review and meta-analysis of cohort studies  
  Kaw R, Hernandez AV, Walker E, Aboussouan L, Mokhlesi B, Chest, 1/1/2009
• Myths and Misconceptions About Alpha-1 Antitrypsin Deficiency  
  Stoller JK, Aboussouan LS, Arch Intern Med, 1/1/2009
• Targeting inflammation in alpha-1 antitrypsin deficiency  
  Aboussouan LS, Stoller JK, Multidisciplinary Respiratory Medicine, 1/1/2007
• High dose intravenous alpha-1-antitrypsin and plasma neutrophil-derived fibrinogen fragments (invited reply to letter)  
  Stoller JK, Aboussouan LD, Thorax, 1/1/2005
• Respiratory disorders in neuromuscular disease (invited reply to letter)  
  Aboussouan LS, Cleve Clin J Med, 1/1/2005
• Effect of acute aminophylline administration on diaphragm function in high cervical tetraplegia  
  Bascom AT, Lattin CD, Aboussouan LS, Goshgarian HG, Chest, 1/1/2005
• Respiratory management in neurological diseases  
  Aboussouan LS, Cleve Clin J Med, 1/1/2005
• Alpha 1-antitrypsin deficienc 5: Intravenous augmentation therapy: current understanding  
  Stoller JK, Aboussouan LS, Thorax, 1/1/2004
• Post-hypoxic ventilatory decline during NREM sleep: influence of sleep apnea  
  Omran AM, Aboubakr SE, Aboussouan LS, Pierchala L, Badr MS, J Appl Physiol, 1/1/2004
• Long-acting inhaled beta-agonists for the treatment of stable chronic obstructive pulmonary disease  
  Dougherty JA, Didur BL, Aboussouan LS, Ann Pharmacother, 1/1/2003
• Effect of noninvasive positive-pressure ventilation on pulmonary function, respiratory muscle strength and arterial blood gases in amyotrophic lateral sclerosis  
  Aboussouan LS, Khan SU, Banerjee M, Arroliga AC, Mitsumoto H, Muscle Nerve, 1/1/2001
• New developments in alpha 1-antitrypsin deficiency  
  Aboussouan LS, Stoller JK, Stoller JK (Guest editor), Chronic Obstructive Pulmonary Disease- Seminars in Respiratory and Critical Care Medicine, 1/1/1999
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Books/Book Chapters

• Egan's Fundamentals of Respiratory Care 
  Chapter: Ch 44. Respiratory Failure and the Need for Ventilatory Support. 
  Page 972 - 986Aboussouan LSEditors: Kacmarek RM, Stoller JK. Heuer AH.Elsevier, St. Louis, MOEdition 11th,2016
• Men’s Health: A Head to Toe Guide for Clinicians. 
  Chapter: Screening and management for pulmonary and sleep issues. 
  Page 35 - 49Aboussouan LSEditors: Potts JM.Springer, New York, NY2016
• The Cleveland Clinic Intensive Review of Internal Medicine 
  Chapter: Ch 35. Obstructive Lung Disease: Asthma and Chronic Obstructive Pulmonary Disease. 
  Page 202 - 204Aboussouan LS, Khatri SBEditors: Stoller J, Nielsen C, Buccola J, Brateanu A.Lippincott Williams and Wilkins, New York, NYEdition 6th,2014
• Egan's Fundamentals of Respiratory Care 
  Chapter: Ch 41. Respiratory Failure and the Need for Ventilatory Support. 
  Page 989 - 1005Aboussouan LSEditors: Kacmarek RM, Stoller JK. Heuer AH.Elsevier, St. Louis, MO2012
• A Case a Week. Sleep Disorders from the Cleveland Clinic. 
  Chapter: Ch 18. This Thing is Impossible! 
  Page 151 - 159Aboussouan LS, Zahand Z, Podmore PEditors: Foldvary N, Krishna J, Budur K.Oxford University Press, New York, NY2011
• A Case a Week. Sleep Disorders from the Cleveland Clinic. 
  Chapter: Ch 23. A Teen with Sleep Apnea sans Acid Maltase - a Tale with a Twist. 
  Page 186 - 190Jaimchariyatam N, Aboussouan LSEditors: Foldvary N, Krishna J, Budur K.Oxford University Press, New York, NY2011
• Alpha-1 Antitrypsin Deficiency. 
  Chapter: Disease manifestations other than the lung and the liver. 
  Page 50 - 63Stoller JK, Aboussouan LSEditors: Bals R, Kohnlein T.Thieme-Publishers, Stuttgart, NY2010
• Educational Review Manual in Pulmonary Disease. 
  Chapter: Bronchiectasis. 
  Page 107 - 138Aboussouan LS, Stoller JKEditors: Doherty DE, Make B.Castle Connolly Graduate Medical Publishing, New York, NYEdition 3rd,2008
• Egan's Fundamentals of Respiratory Care 
  Chapter: Respiratory Failure and the Need for Ventilatory Support. 
  Page 949 - 964Aboussouan LSEditors: Kacmarek R, Wilkins R, Stoller J.Elsevier, St. Louis, MOEdition 9th,2008
• The Cleveland Clinic: Current Clinical Medicine 2009. 
  Chapter: Alpha-1-Antitrypsin Deficiency. 
  Page 537 - 540Anthony AS, Aboussouan LSEditors: Carey WD.Saunders/Elsevier, Philadelphia, PA2008
• COPD. 
  Chapter: Alpha 1-antitrypsin deficiency. 
  Page 447 - 459Aboussouan LS, Stoller JKEditors: Stockley R, Rennard S, Rabe K, Celli B.Blackwell, Oxford, England2007
• Amyotrophic Lateral Sclerosis. 
  Chapter: Respiratory care in ALS. 
  Page 737 - 759Heiman-Patterson T, Aboussouan LSEditors: Mitsumoto H, Przedborski S, Gordon PH.Taylor & Francis, New York, NY2005
• The Cleveland Clinic Intensive Review of Internal Medicine 
  Chapter: Obstructive lung disease : Asthma and chronic obstructive pulmonary disease. 
  Kavuru MS, Aboussouan LSEditors: Stoller J, Michota F, Mandell B.Lippincott Williams and Wilkins, New York, NYEdition 4th,2005
• Management of non-Neoplastic Advanced Lung Disease. Lung Biology in Health and Disease. Vol 176 
  Chapter: Air travel. 
  Page 711 - 730Aboussouan LS, Stoller JKEditors: Maurer JR.Marcel Dekker, Inc., New York, NY2003
• USMLE Step 3 Recall. 
  Chapter: Chronic obstructive Pulmonary Disease, Adult Respiratory Distress Syndrome, Hemoptysis, Sleep Apnea, Solitary Pulmonary Nodule. 
  Aboussouan LSEditors: Ryan M.Lippincott Williams and Wilkins, Philadelphia, PA2002
• Critical Diagnostic Thinking for the Respiratory Clinician: A Case-Based Approach. 
  Chapter: Adult patient with new onset stridor. 
  Page 201 - 210Jamil T, Aboussouan LSEditors: Stoller JK, Bakow ED, Longworth D.W.B. Saunders, Philadelphia, PA2001
• Critical Diagnostic Thinking for the Respiratory Clinician: A Case-Based Approach. 
  Chapter: Progressive exertional dyspnea in a 45 year old. 
  Page 57 - 64Aboussouan LSEditors: Stoller JK, Bakow ED, Longworth D.W.B. Saunders, Philadelphia, PA2001
• Internal Medicine Pearls 
  Chapter: A 45-year-old woman with HIV infection and slowly progressive dyspnea. 
  Page 130 - 132Aboussouan LSEditors: Heffner JE, Sahn SA.Hanley & Belfus, Inc., Philadelphia, PAEdition 2nd,2000
• Comprehensive Respiratory Medicine. 
  Chapter: Other causes of emphysema. 
  Stoller JK, Aboussouan LSEditors: Albert R, Spiro S, Jett J.Mosby International, London, United Kingdom1999
• Rehabilitation of the Patient with Respiratory Disease. 
  Chapter: Perioperative pulmonary care. 
  Page 561 - 573Aboussouan LS, Stoller JKEditors: Cherniack NS, Altose MD, Homma I.McGraw-Hill, New York, NY1998
• Chest Medicine 
  Chapter: Chronic obstructive lung diseases: emphysema, chronic bronchitis, bronchiectasis, and cystic fibrosis. 
  Page 201 - 246Stoller JK, Aboussouan LSEditors: George RB, Light RW, Matthay MA and Matthay RA.Williams & Wilkins, Baltimore, MDEdition 3rd,1995
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Abstracts/Posters

• Impact of pulmonary physiologic and metabolic factors on arterial carbon dioxide levels in obesity hypoventilation syndrome.
  Mehta H, Wang L, Kaw R, Mehra R, Aboussouan LS, Sleep, 1/1/2017
• Course of Decline of Lung Function Based on Tolerance to Non-Invasive Ventilation in Patients with Amyotrophic Lateral Sclerosis.
  Panchabhai TS, Pioro EP, Aboussouan LS, Wang XF, Zhang Q, Mireles-Cabodevila E, Am J Respir Crit Care Med, 1/1/2016
• Predictors of survival in a large cohort of patients with amyotrophic lateral sclerosis.
  Panchabhai TS, Mireles-Cabodevila E, Pioro EP, Aboussouan LS, Am J Respir Crit Care Med, 1/1/2016
• Expiratory time constant and sleep apnea severity in the overlap syndrome.
  Wiriyaporn D, Aboussouan L, Sleep, 1/1/2015
• The natural history of lung function after initiation of non-invasive ventilation in a large cohort of patients with amyotrophic lateral sclerosis.
  Panchabhai TS, Wang XF, Zhang Q, Pioro EP, Mireles-Cabodevila E, Aboussouan LS, Am J Respir Crit Care Med, 1/1/2015
• Postoperative complications in patients with unrecognized obesity hypoventilation syndrome.
  Kaw RK, Bhateja P, Mar HP, Hernandez AV, Ramaswamy A, Deshpande A, Aboussouan LS, Am J Respir Crit Care Med, 1/1/2015
• Using FENO and STOP-BANG scores to predict AHI in OSA patients.
  Chua Ai-Ping, Aboussouan LS, Laskowski D, Minai OA, Dweik RA, Sleep, 1/1/2014
• Outcomes in patients with impaired pulmonary function and obstructive sleep apnea: A retrospective chart review.
  Baumgartner M, Aboussouan LS, Minai O, Sleep, 1/1/2014
• Predicting sleep apnea: The complementary role of FENO and STOP BANG.
  Chua Ai-Ping, Aboussouan LS, Laskowski D, Minai OA, Dweik RA, Am J Respir Crit Care Med, 1/1/2014
• Change in daytime end-tidal CO2 with time in patients with obstructive sleep apnea.
  Kittivoravitkul P, Minai O, Aboussouan LS, Sleep, 1/1/2013
• Impact of epileptic spike density on end-tidal CO2 in patients with intractable epilepsy.
  Herekar AA, Foldvary N, Aboussouan LS, Andrews ND, Moul DE, Tarler M, Sleep, 1/1/2013
• Physical therapy parameters do not predict liberation from prolonged mechanical ventilaton.
  Banga A, Lataifeh AR, Sasidhar M, Aboussouan L, Abunasser J, Crit Care Med, 1/1/2013
• Predictors of successful liberation from ventilator among patients requiring prolonged mechanical ventilation: a one year study.
  Banga A, Lataifeh A, Sasidhar M, Aboussouan L, Abunasser J, Am J Respir Crit Care Med, 1/1/2013
• Diaphragm Position as Predictor of PAP Adherence in Sleep Apnea.
  Garcha PS, Cumbo-Nacheli G, Bae C, Minai O, Aboussouan LS, Sleep, Boston, MA, 1/12/2012
• A model of simulation-based mechanical ventilation teaching for pulmonary and critical care fellows.
  Choi HK, Patel D, Ribeiro Neto M, Sharma M, Farag H, Ashton R, Aboussouan L, Chatburn R, Abunasser J, Zein J, Crit Care Med, 1/1/2012
• Echocardiogram parameters do not predict successful liberation from ventilator among patients requiring prolonged mechanical ventilation.
  Banga A, Lataifeh A, Sasidhar M, Aboussouan L, Abunasser J, Crit Care Med, 1/1/2012
• Obesity Hypoventilation Syndrome: An Emerging and Unrecognized Risk Factor Among Surgical Patients.
  Kaw R, Aboussouan LS, International Conference of the American Thoracic Society, Denver, CO, 1/16/2011
• Cardiorespiratory complications of focal seizures: A pilot study exploring the role of cardiorespiratory dysfunction as a mechanism of sudden unexplained death and epi...
  Fong J, Andrews ND, Aboussouan L, Kayyali HA, Tarler M, Foldvary-Schaefer N, Sleep, 1/1/2011
• Obesity hypoventilation syndrome: an emerging and unrecognized risk factor among surgical patients.
  Kaw R, Pasupuleti V, Thota P, Aboussouan L, Am J Respir Crit Care Med, 1/1/2011
• Clinical and Physiologic Characteristics of Patients with Diaphragm Dysfunction due to Neuralgic Amyotrophy.
  Rice BL, Aboussouan LS, Ashton RW, International Conference of the American Thoracic Society, New Orleans, LA, 1/18/2010
• Determinants of nocturnal hypercapnia in OSA patients.
  Jaimchariyatam N, Dweik RA, Kaw R, Aboussouan LS, Sleep, 1/1/2010
• Change in exhaled nitric oxide levels after sleep in patients with obstructive sleep apnea correlates with OSA severity.
  Chua A-P, Aboussouan LS, Minai O, Laskowski D, Dweik RA, Sleep, 1/1/2010
• Clinical and physiologic characteristics of patients with diaphragm dysfunction due to neuralgic amyotrophy: A Case Series.
  Rice BL, Aboussouan LS, Ashton RW, Am J Respir Crit Care Med, 1/1/2010
• Predictors of continuous positive airway effective pressure during a split-night polysomnogram.
  Zarrouf FA, Polk E, Aboussouan L, AlShaer M, Sleep, 1/1/2010
• Identification of arousals by measurement of rr interval variability.
  Gopinath A, Aboussouan LS, Diaz-Guzman E, Sleep, 1/1/2008
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Lectures

• Sleep and neuromuscular disease, and sleep cases challenges. 
  1/13/2017
• Sleep disorders in ALS. 
  1/6/2017
• Central control of breathing and neuromuscular disorders. 
  Atlanta, GA - 1/28/2016
• Control of breathing 
  1/15/2016
• What is new in COPD, sleep disordered breathing in neuromuscular disease. 
  Abu Dhabi, United Arab Emirates - 1/11/2016
• Positive airway pressure for sleep apneam, advanced PAP therapy, challenging PSG tracings, complex respiratory disorders and sleep. 
  1/11/2016
• Sleep disordered breathing in neuromuscular disease 
  1/27/2015
• Basics of ventilator control and central apnea, Advanced PAP therapy cases, challenging or unusual PAP tracings 
  1/15/2015
• Respiratory and sleep disorders in neuromuscular disease. 
  1/24/2014
• Managing advanced chronic obstructive lung disease: interface with palliative care. 
  1/15/2014
• PAP for sleep apnea; Advanced PAP therapy cases. 
  1/10/2014
• Wake Up to Sleep Disorders 
  Cleveland Clinic - Cleveland, Ohio / The Cleveland Clinic Foundation, Independence, Ohio - 4/17/2013
• Neuromuscular disease and sleep. 
  1/24/2013
• Non-invasive ventilation in restrictive lung disease. 
  Ohio State University - 1/20/2013
• PAP for sleep apnea; Advanced PAP therapy cases 
  1/17/2013
• A Cleveland Clinic Sleep Disorders Center Update. 
  1/17/2013
• COPD from Bench to Bedside. The changing epidemiology of COPD, Management of acute exacerbations of COPD. 
  1/15/2013
• Chronic Obstructive Pulmonary Disease. 
  Cleveland Clinic Foundation, OH - 1/4/2013
• Sleep apnea. 
  Lakewood Hospital - 1/28/2012
• Etiology, pathogenesis, and epidemiology of stable COPD. 
  Cleveland Clinic Foundation, OH - 1/25/2012
• Control of breathing in sleep. 
  Cleveland Clinic Foundation, OH - 1/20/2012
• Sleep apnea diagnosis and management. 
  Cleveland Clinic Foundation, OH - 1/11/2012
• Interpretation of Polysomnography 
  Beirut, Lebanon - 1/9/2012
• New Drugs in COPD. Where do they fit in? 
  1/9/2012
• Recent developments in the diagnosis pathogenesis and treatment of COPD. 
  Cleveland Clinic Foundation, OH - 1/21/2010
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Other

• Treatment of sleep-disordered breathing in patients with neuromuscular disease. A review of our approach. 
  Aboussouan LS, Mireles-Cabodevila E, Consult QD
  https://consultqd.clevelandclinic.org/2017/05/treatment-sleep-disordered-breathing-patients-neuromuscular-disease/
  1/1/2017
• ABG procedure. 
  Aboussouan LS, ACP Smart Medicine
  http://smartmedicine.acponline.org/
  1/1/2016
• Emphysema-like disease in HIV. Invited Review. 
  Aboussouan LS, UpToDate
  www.uptodate.com
  1/1/2016
• Noninvasive positive pressure support. Disease Management Project. 
  Aboussouan LS, Mireles-Cabodevila E; Carey W., Editor, Cleveland Clinic Center for Continuing Education Disease
  http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/pulmonary/noninvasive-positive-pressure/
  1/1/2014
• Sleep disordered breathing. Disease Management Project. 
  Garcha PS, Aboussouan LS, Minai O; Carey W., Editor, Cleveland Clinic Center for Continuing Education Disease
  http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/pulmonary/sleep-disordered-breathing/
  1/1/2013
• Pharmacotherapy in the management of stable chronic obstructive pulmonary disease. 
  Hatipoglu U, Aboussouan LS, Hospital Physician Board Review Manuals. Pulmonary Disease
  http://www.turner-white.com/brm/bpulm.htm
  1/1/2013
• Alpha-1 Antitrypsin Deficiency. 
  Stoller JK, Lacbawan FL, Aboussouan LS (Pagon RA, Adam MP, Ardinger HH, et al., editors), GeneReviews
  http://www.ncbi.nlm.nih.gov/books/NBK1519/
  University of Washington, Seattle, WA - 1/27/2006
• Flow-volume loops 
  Aboussouan LS, Stoller JK
  http://www.uptodate.com/contents/flow-volume-loops
  UpToDate, Wolters Kluwer Health - 2012-07-18
• Emphysema-like disease in HIV infection 
  Aboussouan LS
  http://www.uptodate.com/contents/emphysema-like-disease-in-hiv-infection
  UpToDate, Wolters Kluwer Health - 2012-06-18
• Role of mucoactive agents in the treatment of COPD 
  Aboussouan LS
  http://www.uptodate.com/contents/role-of-mucoactive-agents-in-the-treatment-of-copd
  UpToDate, Wolters Kluwer Health - 2012-03-16
• Management of Respiratory Problems in the Patient with Amyotrophic Lateral Sclerosis. PCCU Online. Lesson 22, Volume 17. 
  Aboussouan LS, American College of Chest Physicians
  www.chestnet.org/education/online/pccu
• Aboussouan LS, Stoller JK. Flow-volume loops. Invited Review. 
  Aboussouan LS, UpToDate
  www.uptodate.com
• Role of mucoactive agents in the treatment of COPD. Invited Review. 
  Aboussouan LS, UpToDate
  www.uptodate.com
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