LouisVignatiMD

PubMed

• 255 citations
  Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment. Multicenter Insulin Lispro Study Group.
  James H. Anderson, Rocco L. Brunelle, Veikko A. Koivisto, Andreas Pfützner, Michael E. Trautmann
  Diabetes. 1997-02-01
• 472 citations
  Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans
  Brian Finan, Tao Ma, Nickki Ottaway, Timo D. Müller, Kirk M. Habegger
  Science Translational Medicine. 2013-10-30
• 212 citations
  The Sustained Effects of a Dual GIP/GLP-1 Receptor Agonist, NNC0090-2746, in Patients with Type 2 Diabetes.
  Juan Pablo Frias, Edward J. Bastyr, Louis Vignati, Matthias H. Tschöp, Christophe Schmitt
  Cell Metabolism. 2017-08-01

Journal Articles

• Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans  
  B. Finan, T. Ma, N. Ottaway, T. D. Muller, K. M. Habegger, K. M. Heppner, H. Kirchner, J. Holland, J. Hembree, C. Raver, S. H. Lockie, D. L. Smiley, V. Gelfanov, B. Ya..., Sci. Transl. Med., 1/1/2013
• Oral protein kinase C Beta inhibition using Ruboxistaurin: Efficacy, Safety, and Causes of Vision Loss Among 813 Patients (1,392 Eyes) with Diabetic Retinopathy in the...  
  Aiello LP, Vignati L, Sheetz MJ, Zhi X, Girach A, Davis MD, Wolka AM, Shahri N, Milton RC; for the PKC-DRS and PKC-DRS2 Study Groups, 1/20/2011
• Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema Invest Ophthalmol  
  Davis MD, Sheetz MJ, Aiello LP, Milton RC, Danis RP, Zhi X, Girach A, Jimenez MC, Vignati L; PKC-DRS2 Study Group, Vis Sci, 1/1/2009
• Effect of Ruboxistaurin in patients with Diabetic Macular Edema: thirty Month results of the randomized PKC-DMES clinical tria  
  The PKC-DRS Study Group, The PKC-DRS Study Group, 1/1/2007
• Diabetic Microvascular complications- can the presence of one predict the development of another  
  Girach A. Vignati L, Journal of Diabetes and its Complications, 1/1/2006
• The effect of ruboxistaurin on visual loss inpatients with moderately severe to very severe nonproliferative retinopathy: Initial results of the Protein Kinase C beta ...  
  The PKC-DRS Study Group, Diabetes, 1/1/2005
• Factors Associated with Nocturnal Hypoglycemia Among Patients with Type 2 Diabetes New to Insulin Therapy: Experience with Lispro  
  Bastyr EJ, Huang Y, Brunelle RL, Vignati L, Cox DJ, Kotsanos JG, Diabetes, and Metabolism, 1/1/2000
• Insulin Lispro in the Treatment of Patients with Type 2 Diabetes Mellitus After Oral Agent Failure  
  Bastyr EJ, Johnson ME, Trautmann, Anderson JH, Vignati L, Clinical Therapeutics, 1/1/1999
• Basal Activity Profiles of NPH and [ Nepsilon-palmitoyl Lys (B29)] Human insulin in Subjects with IDDM  
  Radziuk J, Pye S, Bradley B, Braaten J, Vignati L, Roach P, Bowsher R, Dimarchi R, Chance R, Diabetologia, 1/1/1998
• Improved Mealtime Treatment using Insulin  
  Anderson JH, Brunelle RL, Koivisto VA, Trautmann ME, Vignati L, Dimarchi R, Multicenter Insulin Lispro Study Group. ClinicalTherapeutics, 1/1/1997
• Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment  
  Anderson JH Jr. Brunelle RL. Koivisto VA. Pfutzner A. Trautmann ME. Vignati L. DiMarchi R, Clinical Trial, Journal Article, Multicenter Study, Randomized Controlled Trial, Diabetes, 1/1/1997
• Mealtime Treatment with Insulin analog Improves Postprandial Hyperglycemia and Hypoglycemia in Patients with Non Insulin dependent Diabetes Mellitus Multicenter Insuli...  
  Anderson JH, Brunelle RL, Keohane P, Koivisto VA, Trautmann ME, Vignati L, Dimarchi R, Archives of Internal Medicine, 1/1/1997
• Efficacy of Insulin Lispro in Combination with NPH Human Insulin, Given Twice per Day in IDDM and NIDDM Patients  
  Vignati L, Anderson JH Jr., Iversen PW, Clinical Therapeutics, 1/1/1997
• Health-Related Quality-of-Life Results from Multinational Clinical Trials of Insulin Lispro  
  Kotsanos JG, Vignati L, Huster W, Andrejasich C, Boggs MB, Jacobson AM, Marrero D, Mathias SD, Patrick D, Zalani S, Anderson J, Diabetes Care, 1/1/1997
• Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment  
  Anderson JH Jr, Brunelle RL, Koivisto VA, Pfutzner A, Trautmann ME, Vignati L, DiMarchi R, Multicenter Insulin Lispro Study Group. Diabetes, 1/1/1997
• Pre-meal insulin analogue insulin lispro vs Humulin ® insulin treatment in young subjects with type 1 diabetes  
  Garg SK, Carmain JA, Braddy KC, Anderson JH, Vignati L, Jennings MK, Chase HP, Diabetic Medicine, 1/1/1996
• Serum leptin levels in women with anorexia nervosa  
  Grinspoon S. Gulick T. Askari H. Landt M. Lee K. Anderson E. Ma Z. Vignati L. Bowsher R. Herzog D. Klibanski A, Journal of Clinical Endocrinology & Metabolism, 1/1/1996
• Pre-meal insulin analogue insulin lispro vs Humulin R insulin treatment in young subjects with type 1 diabetes  
  Garg SK. Carmain JA. Braddy KC. Anderson JH. Vignati L. Jennings MK. Chase HP, Diabetic Medicine, 1/1/1996
• Serum leptin levels in women with anorexia nervosa  
  Grinspoon S, Gulick T, Askari H, Landt M, Lee K, Anderson E, Ma Z, Vignati L, Bowsher R, Herzog D, Klibanski A, Journal of Clinical Endocrinology and Metabolism, 1/1/1996
• Hypogonadotrophic Secondary Amenorrhea in Diabetes: Effects of Central Opiate Blockade and Improved Metabolic Control  
  O'Hare JA, Vignati L, Eichold B, American Journal of Medicine, 1/1/1987
• Insulin pumps: when are they indicated, what can they do?  
  Vignati L, Transactions of the Association of Life Insurance Medical Directors of America, 1/1/1985
• Questions and answers on diabetes A panel discussion  
  Bower BF, Flier J, Vignati L, Felig P, Transactions of the Association of Life Insurance Medical Directors of America, 1/1/1985
• Continuous Subcutaneous Insulin Therapy During Early Pregnancy  
  Kitzmiller JL, Younger DM, Hare J, Phillipe M, Vignati L, Fargnoli B, Grause A, Obstetrics and Gynecology, 1/1/1985
• Insulin Pumps: The Patients’ Verdict  
  Fredholm N, Vignati L, Brown S, American Journal of Nursing, 1/1/1984
• Abnormal Dexamethasone Suppression Test in Diabetes Mellitus  
  Hudson JI, Hudson MS, Rothchild AJ, Vignati L, Schatzberg AF, Melby JM, Archives of General Psychiatry, 1/1/1984
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Books/Book Chapters

• Phase III Clinical Studies Peptides: Chemistry, Structure and Biology 
  Chapter: Design of an Optimal Mealtime Insulin (Lys-Pro) and its Assessment 
  Anderson J, Chance R, Slieker L, Vignati L, DiMarchi R1996
• Organ Transplantation Replacement 
  Chapter: Replacement of Pancreatic Function Through the Use of Mechanical or Electronic Devices 
  Vignati L, Edelman, SVEditors: Cerilli, J.1987
• Joslins Diabetes Mellitus 
  Chapter: Exercise and Diet 
  Vignati L, Cunningham LNEdition 12th,1985
• Joslins Diabetes Mellitus 
  Chapter: Coma in Diabetes 
  Vignati L, Asmal AC, Black WL, Brink SJ, Hare JWEdition 12th,1985
• Chronic Experiments Trace Substance in Environment Health, VI 
  Chapter: Mutual Antagonistic and Synergistic Effects of Inorganic Selenium and Mercury Salts 
  Groth DH, Vignati L., et alEditors: D.D. Hemphill.1973
• Extra-Pulmonary Manifestation of Respiratory Disease 
  Chapter: Biochemical Abnormalities Produced by Acid-Base Disturbances 
  Vignati L, Cahill Jr. GFEditors: E.D. Robin.
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Abstracts/Posters

• Diabetic Macular Edema, Relationship of Visual Acuity to Involvement of the Center of the Macula
  Sheetz, Matthew J.; Aiello, Lloyd P.; Davis, Matthw D.; Milton, Roy C.; Arora, Vipin; Hu, Kuolung; Girach, Aniz;, Vignati, Louis, Diabetes, 1/1/2004
• Diabetic Retinopathy and Macular Edema Progression Rates in Recent Placebo-Controlled Clinical Trials
  Davis, Matthew; Aiello, Lloyd; Milton, Roy; Sheetz, Matthew; Arora, Vipin; Vignati, Louis, PKC-DRS and PKC-DMES Study Groups, Diabetes, 1/1/2003
• Ruboxistaurin (RBX) Mesylate Treatment in Patients with Diabetic Peripheral Neuropathy (DPN) Improves Clinical Global Impression (CGI) and Correlates with Change in Pa...
  Bastyr, Edward III; Price Karen; Skljarevski, Vladimir; Lledo Alberto; Vignati, Louis, Diabetes, 1/1/2003
• Initial Results of the Protein Kinase C b Inhibitor Diabetic Retinopathy Study (PKC-DRS)
  Milton, Roy; Aiello, Lloyd; Davis, Matthew; Sheetz, Matthew; Arora Vipin; Vignati, Louis; PKC-DRS Study Group, Diabetes, 1/1/2003
• Efficacy of [Lys(B28),Pro(B29)] Human Insulin in a One Year Global Randomized Clinical Trial
  Vignati L, Anderson JH, Brunelle RL, Diabetes, 1/1/1994
• Development and Validation of a Diabetes Quality of Life Questionnaire for Use in Global Clinical Trials
  Kotsanos J, Huster W, Andrejasich C, Vignati L, Mathias S, Patrick D, Diabetes, 1/1/1994
• Decreased Rate of Hypoglycemia in Association with Improved Metabolic Control with Insulin LisPro
  Brunelle RL, Anderson JH, Vignati L, Diabetologia, 1/1/1994
• Improvement of Glycemic Control with the Rapidly Absorbed LisPro Insulin Analog in Type I Diabetes
  Vignati L, Anderson JH, Brunelle RL, Jefferson F, Richardson M, Diabetologia, 1/1/1994
• Fluctuating Massive Insulin Resistance in Lipoatrophic Diabetes with a Novel T-Cell Disorder
  O'Hare JA, Rabinowe S, Catanese V, Baldini M, Vignati L, Diabetes, 1/1/1985
• Diabetic Secondary Amenorrhea Absence of a Pituitary Defect, Absence of Opioid GnRH Inhibition and Failure to Respond to Improved Metabolic Control
  Vignati L, O'Hare JA, Eichold B, Dunn F, Diabetes, 1/1/1985
• Marked Decrease in Insulin Requirement in Diabetics During Labor and Delivery
  Younger MD, Vlachokosta R, Kitzmiller J, Vignati L, Diabetes, 1/1/1980
• Assessment of Glycemic Control in IDDM with and without Diabetic Complications Utilizing Open Loop Insulin Systems
  Vignati L, Arastu M, Ryan P, Miller P, Diabetes, 1/1/1980
• Effects of Insulin and Exercise on Forearm Metabolism in Fasting Man
  Finley RJ, Vignati L, Aoki TT, Clinical Research, 1/1/1978
• Substrate Utilization in Perfused Human Kidney
  Vignati L, Chos, Aoki TT, Clinical Research, 1/1/1977
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Other

• Sustained moderate visual loss as a predictive end point for visual loss in non-proliferative diabetic retinopathy 
  A Girach, L P Aiello, R C Milton, M D Davis, R P Danis, X Zhi, M J Sheetz and L Vignati, Eye
  1/7/2008
• Protein Conservation During Fasting: A Function of Triiodothyronine Levels: Transactions American Association of Physicians, Volume ICI 
  Vignati L, Finley R, Hagg S, Aoki TT
  1/1/1978