LouisHPhilipsonMDPhD FACP(He/Him)

PubMed

• 51 citations
  Integrated Pancreatic Blood Flow: Bidirectional Microcirculation Between Endocrine and Exocrine Pancreas.
  Michael P. Dybala, Andrey V. Kuznetsov, Maki Motobu, Bryce Hendren-Santiago, Louis H. Philipson
  Diabetes. 2020-03-16
• 176 citations
  Effect of Continuous Glucose Monitoring on Hypoglycemia in Older Adults With Type 1 Diabetes: A Randomized Clinical Trial.
  Richard E. Pratley, Lauren Kanapka, Michael R. Rickels, Andrew J. Ahmann, Grazia Aleppo
  JAMA. 2020-06-16
• 115 citations
  Type 2 Diabetes and Congenital Hyperinsulinism Cause DNA Double-Strand Breaks and p53 Activity in β Cells
  Sharona Tornovsky-Babeay, Daniela Dadon, Oren Ziv, Elhanan Tzipilevich, Tehila Kadosh
  Cell Metabolism. 2014-01-07

Journal Articles

• Effect of Continuous Glucose Monitoring on Hypoglycemia in Older Adults with Type 1 Diabetes  
  Anuj Bhargava, Robin Goland, Irl B Hirsch, Yogish C Kudva, Janet B Mcgill, Louis Philipson, Francesco Vendrame, Ruth S Weinstock, JAMA
• Characterization of Mice Expressing Ins1 Gene Promoter Driven CreERT Recombinase for Conditional Gene Deletion in Pancreatic Beta-cells  
  Tamarina NA, Roe MW, Philipson L, Islets, 1/1/2014
• Distribution of Directional Change as a Signature of Complex Dynamics  
  Burov, S., Tabei, Ali S.M., Huynh, T., Murrell, M., Philipson, L.H., Rice, S.A., Gardel, M.L., Scherer, N.F., Dinner, A.R., Proc Natl Acad Sci U S A., 1/3/2013
• Metastatic Insulinoma Following Resection of Non-secreting Pancreatic Islet Cell Tumor,  
  Koshy, A., Gordon, I.O., Van Ha, T.G., Kaplan, E.L., Philipson, L.H., Journal of Investigative Medicine High Impact Case Reports, 1/1/2013
• Human Insulin Gene Mutant C43G Is Retained in the ER but Does Not Impair Glucose Homeostasis in Zebrafish  
  Eames, SC, Kinkel, MD, Rajan, S., Prince, VE, Philipson LH, J Diabetes Invest, 1/1/2013
• Genetics and Pathophysiology of Neonatal Diabetes Mellitus H  
  Naylor, RN, Greeley, SAW, Bell, GI, Philipson, LH, Journal of Diabetes Investigation, 1/1/2011
• In Vitro Processing and Secretion of Mutant Insulin Proteins That Cause Permanent Neonatal Diabetes  
  Rajan, S, Eames, SC, Park, SY, Labno, C, Bell, GI, Prince, VE, Philipson, LH., Am. J. Physiol. Endo Metab., 1/1/2010
• Neonatal Diabetes Mellitus: A Model for Personalized Medicine  
  Greeley, S.A.W., Tucker, S.E., Naylor, R.N., Bell, G.I., and Philipson, L.H., Trends in Endocrinology and Metabolism, 1/1/2010
• A Brief Perspective on Insulin Production  
  Steiner DF, Park SY, Stoy J, Philipson LH, Bell GI., Diabetes Obes Metab., 1/1/2009
• A Model of Action Potentials and Fast Ca2+ Dynamics in Pancreatic Beta-cells  
  Fridlyand, LE, Jacobson, D., and Philipson, L.H., Biophys J., 1/1/2009
• Reversible Translocation of EYFP-tagged STIM1 Is Coupled to Calcium Influx in Insulin Secreting Beta-cells  
  Tamarina NA, Kuznetsov A, Philipson LH., Cell Calcium., 1/1/2008
• Single Particle Image Reconstruction of the Human Recombinant Kv21 Channel  
  Adair B, Nunn R, Lewis S, Dukes I, Philipson L, Yeager M., Biophys J., 1/1/2008
• Diagnosis and Treatment of Neonatal Diabetes: An United States Experience  
  Stoy J, Greeley SA, Paz VP, Ye H, Pastore AN, Skowron KB, Lipton RB, Cogen FR, Bell GI, Philipson LH; United States Neonatal Diabetes Working Group, Pediatr Diabetes., 1/1/2008
• Glucose Homeostasis, Insulin Secretion, and Islet Phospholipids in Mice that Overexpress iPLA2Beta in Pancreatic Beta-Cells and in iPLA2Beta-Null Mice  
  Bao, S., Jacobson, D.A., Wohltmann, M., Bohrer, A., Jin, W., Philipson, L.H. and Turk, J., Am. J. Physiol, 1/1/2008
• Insulin Mutation Screening in 1044 Patients with Diabetes: Mutations in the INS gene are a Common Cause of Neonatal Diabetes but a Rare Cause of Diabetes Diagnosed in ...  
  Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, Macdonald MJ, Stoy J, Steiner DF, Philipson LH, Bell..., Diabetes, 1/1/2008
• Kv21 Ablation Alters Glucose Induced Islet Electrical Activity, Enhancing Insulin Secretion  
  Jacobson DA, Kuznetsov A, Lopez JP, Kash S, ammala CE, Philipson LH., Cell Metabolism, 1/1/2007
• A Protective Role for Nitric Oxide during the Endoplasmic Reticulum Stress Response in Pancreatic Beta-cells  
  Kitiphongspattana K, Khan TA, Ishii-Schrade K, Roe MW, Philipson LH, Gaskins HR, Am J Physiol Endocrinol Metab., 1/1/2007
• Modulation of the Pancreatic Islet betaCell-delayed Rectifier Potassium Channel Kv21 by the Polyunsaturated Fatty Acid Arachidonate  
  Jacobson DA, Weber CR, Bao S, Turk J, Philipson LH., J Biol Chem, 1/1/2007
• Insulin Gene Mutations as a Cause of Permanent Neonatal Diabetes  
  Stoy, J., Edghill, E.L., Flanagan S.E., Ye, H., Paz V.P., Pluzhnikov, A., Below, J.E. Hayes, M.G. Cox, N.J. Lipkind, G.M., Lipton, R.B., Greeley, S.A., Patch, A.-M. El..., Proc Nat Acad USA, 1/1/2007
• Regulation of cAMP Dynamics by Ca2+ and G-protein Coupled Receptors in the Pancreatic Beta-cell: A Computational Approach  
  Fridlyand LE, Harbeck MC, Roe MW, Philipson LH, Am J Physiol Cell Physiol., 1/1/2007
• Reversal of Diabetes in NOD Mice without Spleen-cell Derived Beta-cell Regeneration  
  Chong, A.S., Shen, J., Tao, J., Yin, D., Kuznetsov, A., Hara, M., and Philipson, L.H., Science, 1/1/2006
• Reactive Species, Cellular Repair and Risk Factors in the Onset of Type 2 Diabetes Mellitus: Review and Hypothesis  
  Fridlyand, L.E. and Philipson, L.H., Current Diabetes Reviews, 1/1/2006
• Oxidative Reactive Species in Cell Injury: Mechanisms In Diabetes Mellitus and Therapeutic Approaches  
  Fridlyand, L.E., Philipson, L.H., Ann N.Y. Acad Sci., 1/1/2006
• Reactive Species and Early Manifestation of Insulin Resistance In Type 2 Diabetes  
  Fridlyand, L.E., Philipson L.H., Diabetes Obes Metab., 1/1/2006
• Improved Outcomes in Islet Isolation and Transplantation by the Use of a Novel Hemoglobin-based O2 Carrier  
  Avila, J., Wong, Y., Barbaro, B., Gangemi, A., Qi, M., Knechle, J., Doubleday, N., Doubleday, M., Churchill, T., Salehi, P., Philipson, L., Shapiro, J., Benedetti, E.,..., Am J Transplant., 1/1/2006
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Books/Book Chapters

• Endocrine Essentials, Endocrine Update for General Medicine 
  Chapter: Monogenic Diabetes: Who Needs MODY Screening? 
  Page 62 - 70Philipson, LH, Naylor, R., Greeley SA, Bell, GI.Editors: Anawalt, BD.The Endocrine Society2012
• Genetic Diagnosis of Endocrine Disorders 
  Chapter: Genetic Testing in Diabetes Mellitus: A Clinical Guide to Monogenic Diabetes 
  Philipson LH, Murphy R, Ellard S, Hattersley AT, Stoy J, Greeley SA, Bell GI, Polonsky KSEditors: Weiss RE, Refetoff S.London, Elsevier2010
• "TRP Channels in Health and Disease” in the Series "Handbook of Experimental Pharmacology 
  Chapter: TRP Channels of the Pancreatic Beta Cell 
  Jacobson, D.A. and Philipson, L.H.Springer-Verlag, Berlin2007
• Commentaries on Perspectives in Diabetes 
  Chapter: Commentary: K+ channels: Generating Excitement in Pancreatic b-Cells. 
  Page 279 - 290Philipson, L.H. and Dukes, I.D.Editors: Robertson, R.P..American Diabetes Association2006
• Landmark Papers in Insulin Biosynthesis 
  Chapter: Foreword 
  A. Lernmark, O. Madsen, and L. H. PhilipsonEditors: Steiner, D.F..Current Medicine Group, London2005
• Diabetes Mellitus: A Fundamental and Clinical Text 
  Chapter: Electrophysiology of the Pancreatic B-cell 
  Houamed, K., Fu, J., Roe, M.W., and Philipson L.H.Editors: LeRoith, D., Taylor, S.I., and Olefsky, J.O..Lippincott, Williams and WilkinsEdition 3,2004
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Lectures

• Can We Prevent Type 1 Diabetes 
  Cairo, Egypt - 1/1/2015
• Insulin Gene Mutations 
  Jerusalem, Israel - 1/1/2015
• Monogenic Genes in Type 2 Diabetes 
  Vancouver, Canada - 1/1/2015
• Monogenic Diabetes and Personalized Genetic Medicine 
  University of Pennsylvania Medicine, Philadelphia, PA - 1/1/2015
• The Clinical & Genetic Spectrum of Monogenic Diabetes 
  Chicago, IL - 1/1/2014
• Subtypes of Type 2 Diabetes in Adults 
  San Francisco, CA - 1/1/2014
• Monogenic Diabetes (Lessons from the University of Chicago) 
  Bangalore, India - 1/1/2014
• Starting Insulin 
  Bangalore, India - 1/1/2014
• Overcoming Barriers to Insulin Use 
  Bangalore, India - 1/1/2014
• Monogenic Diabetes and Beta Cell Dynamics 
  Montreal Diabetes Research Center, Montreal, Canada - 1/1/2014
• Type 1 Diabetes 
  Chicago IL - 1/1/2014
• Update in Diabetes Research and Technology: The Onramp to the Diabetes Digital Highway 
  1/1/2014
• State of Diabetes 
  Springfield, Illinois - 1/1/2014
• Monogenic Diabetes and the Beta Cell 
  Naomi Berrie Diabetes Center, Columbia University, NY, NY - 1/1/2014
• An Imaging-modeling Approach to Insulin Granule Dynamics 
  Kyoto International Conference Center, Kyoto, Japa - 1/1/2013
• Monogenic Diabetes: Lessons from the Chicago Registry 
  Section of Endocrinology, University of Chile, Santiago, Chile - 1/1/2013
• Insulin Mutations and Granule Dynamics 
  New Haven, CN - 1/1/2013
• Mental Health Issues In Diabetes: The Chicago Model 
  Philadelphia, PA - 1/1/2013
• Diabetes 101 
  Chicago, IL - 1/1/2013
• Update in Monogenic Diabetes 
  University of Chicago Kovler Diabetes Center - 1/1/2013
• Monogenic Diabetes (Lessons Learned) 
  Bangalore, India - 1/1/2012
• Incretins in Metabolism 
  Bangalore, India - 1/1/2012
• Cellular Aspects of GPCRs in the Beta Cell 
  Bangalore, India - 1/1/2012
• Case studies in Monogenic Diabetes 
  Bangalore, India - 1/1/2012
• Case Studies in Hypoglycemia 
  Bangalore, India - 1/1/2012
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Other

• Interview on “Good Morning Ireland” 
  RTE 1 (Raidio Teilifis Eireann)
  http://www.rte.ie/player/us/show/10243456/#pos=1162
  1/17/2012
• Monogenic Diabetes 
  WGN/CLTV
  http://www.cltv.com/wgntvmonogenic-diabetes-20120203,0,1917756.story
  Chicago, IL - 1/1/2012
• Diabetes Awareness 
  NBC Chicago Non-Stop Channel “Weekends with Whitney”
  1/1/2011
• Diabetes and the Student Athlete 
  WCIU-TV 26.1 Chicago, Kenny McWilliams show
  1/1/2011
• Funding for Diabetes Research 
  Philipson, LH, Reedy, P. Flom, J., Chicago Tribune
  1/26/2010
• Baseball and Growth Hormones: Big Muscles, Big Bodies, Big Trouble. Letter 
  Landau, R. and Philipson, L.H., The Wall Street Journal
  1/20/2007
• Visualizing Calcium Signaling in Cells by Digitized Conventional Wide-field and Confocal Fluorescence Microscopy 
  Roe, M.W., Fiekers, J.F., Philipson, L.H., and Bindokas, V.P., Humana Press Handbook
  1/1/2005
• Insulin Biosynthesis, Secretion, Structure, And Structure-Activity Relationships 
  Pittman, I., Philipson, L.H., Steiner, D.F., “Endocrinology”
  http://www.endotext.org/index.htm
  1/1/2004
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