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Office
20271 Goldenrod Ln
Germantown Innovation Center
Germantown, MD 20876
Summary
- RNA Trans-splicing, Gene Editing
Education & Training
- George Washington UniversityResidency, Pathology-Anatomic and Clinical, 1992 - 1995
- University of South Florida MorsaniInternship, Internal Medicine, 1984 - 1985
- University of Maryland School of MedicineClass of 1984
Certifications & Licensure
- MD State Medical License 1985 - 2025
Publications & Presentations
PubMed
- 60 citationsMessenger RNA repair and restoration of protein function by spliceosome-mediated RNA trans-splicing.Madaiah Puttaraju, Janet DiPasquale, Carl C Baker, Lloyd G. Mitchell, Mariano A. Garcia-Blanco
Molecular Therapy. 2001-08-01 - 46 citationsSpliceosome-mediated RNA trans-splicing with recombinant adeno-associated virus partially restores cystic fibrosis transmembrane conductance regulator function to pola...Xiaoming Liu, Meihui Luo, Liang Zhang, Ziying Yan, Roman Zak
Human Gene Therapy. 2005-09-08 - 22 citationsSpliceosome-Mediated Pre-mRNA trans-Splicing Can Repair CEP290 mRNA.Scott J. Dooley, Devin S. McDougald, Krishna J. Fisher, Bennicelli Jeanette, Lloyd G. Mitchell
Molecular Therapy. Nucleic Acids. 2018-09-07
Grant Support
- Development Of Tools To Modify Globin Gene Expression In Stem CellsNational Heart, Lung, And Blood Institute2011
- Optimization Of A Method To Reduce Expression Of Progerin, The Cause Of HGPS (ProNational Institute On Aging2010
- Development Of Smart Gene Therapy For Cystic FibrosisNational Institute Of Diabetes And Digestive And Kidney Diseases2003
- Trans-Splicing To Repair Cystic Fibrosis MRNANational Institute Of Diabetes And Digestive And Kidney Diseases2000–2001
- Spliceosome Trans-Splicing To Repair CF MRNANational Institute Of Diabetes And Digestive And Kidney Diseases1999
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