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Office
8 The Green, Suite 5586
Dover, DE 19901
Summary
- Liza Squires, MD currently serves as the Chief Medical Officer at Neuren Pharmaceuticals. Her career has focused on the development of novel therapeutics for diseases of the Central Nervous System that affect children. Over the past decade, she has concentrated on genetically targeted treatments for children. Liza began her career in academic, hospital-based child neurology where the unmet need for therapeutic options drew her to a career in drug development. Over the past 20 years, she has held positions of increasing responsibilities in both early and late-stage development at Johnson and Johnson, Shire Pharmaceuticals, Lumos Pharma, Aevi Genomic Medicine and Origin Biosciences. She has led and contributed to multiple NDAs and sNDAs resulting in global regulatory approvals for Topamax® (topiramate), Daytrana® (methylphenidate transdermal system), Vyvanse® (lisdexamfetamine dimesylate), Intuniv® (guanfacine ER) and Nulibry® (fosdenopterin). Liza is the author of many referenced publications in peer-reviewed journals and has been active in advocacy groups for the advancement of pediatric therapeutics. She received her B.S. from the University of Michigan and M.D. from Michigan State University. She trained in general pediatrics at Yale University and did her residency in Child Neurology at Massachusetts General Hospital. Liza is board certified in General Pediatrics and Neurology with Special Competence in Child Neurology.
Education & Training
- Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1989 - 1992
- Yale-New Haven Medical CenterResidency, Pediatrics, 1987 - 1989
- McGaw Medical Center of Northwestern UniversityResidency, Pediatrics, 1986 - 1987
- OtherClass of 1986
Certifications & Licensure
- MI State Medical License 1993 - 2021
- American Board of Pediatrics Pediatrics
- American Board of Psychiatry and Neurology Neurology with Special Qualification in Child Neurology
Clinical Trials
- Efficacy and Safety of NFC-1 in Adolescents With Genetic Disorders Impacting mGluR and ADHD Start of enrollment: 2016 Jun 01
- A Noninterventional Genotype/Phenotype Study of mGluR Mutations in Children and Adolescents With ADHD Start of enrollment: 2016 Feb 01
- Study of ORGN001 (Formerly ALXN1101) in Neonates, Infants and Children With Molybdenum Cofactor Deficiency (MOCD) Type A Start of enrollment: 2016 May 01
Publications & Presentations
PubMed
- 16 citationsMolybdenum cofactor deficiency: A natural history.Ronen Spiegel, Bernd C Schwahn, Liza Squires, Nils Confer
Journal of Inherited Metabolic Disease. 2022-05-01 - 7 citationsIndustry and Patient Perspectives on Child Participation in Clinical Trials: The Pediatric Assent Initiative Survey Report.Donald P. Lombardi, Liza Squires, Philip Sjostedt, Irmgard Eichler, Mark A. Turner
Therapeutic Innovation & Regulatory Science. 2018-01-01 - 13 citationsBest Practice Recommendations Regarding the Assessment of Palatability and Swallowability in the Development of Oral Dosage Forms for Pediatric PatientsCharles Thompson, Don Lombardi, Philip Sjostedt, Liza Squires
Therapeutic Innovation & Regulatory Science. 2015-03-11
Press Mentions
- Veristat Congratulates Origin Biosciences for FDA Approval of Nulibry During the Week of Rare Disease Day 2021March 8th, 2021
- Zynerba Pharmaceuticals Announces Oral Presentation of ZYN002 Data at the 16th NFXF International Fragile X Conference in July 2018April 23rd, 2018
- Aevi Genomic Medicine to Present Updated Results from SAGA Trial of AEVI-001 at the 6th World Congress on ADHDApril 12th, 2017
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