LijunYangMD

PubMed

• 518 citations
  Irisin Stimulates Browning of White Adipocytes through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling
  Yuan Zhang, Rui Li, Yan Meng, Shiwu Li, William Donelan
  Diabetes. 2014-02-01
• 123 citations
  Irisin exerts dual effects on browning and adipogenesis of human white adipocytes.
  Yuan Zhang, Chao Xie, Hai Wang, Robin M. Foss, Morgan Clare
  American Journal of Physiology. Endocrinology and Metabolism. 2016-08-01
• 18 citations
  NF-E2-Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus.
  Shuhong Han, Haoyang Zhuang, Pui Y. Lee, Mingjia Li, Li-Jun Yang
  Arthritis & Rheumatology. 2020-08-09

Journal Articles

• Transient receptor potential melastatin 4 channel is required for rat dental pulp stem cell proliferation and survival  
  Ngoc Tran TD, Stovall KE, Suantawee T, Hu Y, Yao S, Yang LJ, Adisakwattana S, Cheng H, Cell Prolif, 1/1/2017
• Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction  
  Zhang Y, Mu Q, Zhou Z, Song H, Zhang Y, Wu F, Jiang M, Wang F, Zhang W, Li L, Shao L, Wang X, Li S, Yang LJ, Wu Q, Zhang M, Tang D, PLoS One, 1/29/2016
• Cell-permeable Peptide Blocks TLR4 signaling and Improves Islet Allograft Survival  
  Dong H, Zhang Y, Song L, Kim D, Wu H, Yang LJ, Li S, Morgan KA, Adams, DB, Wang H, Cell Transplantation, 1/13/2016
• Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase  
  Zhang Y, Li S, Donelan W, Xie C, Wang H, Wu Q, Purich DL, Reeves WH, Tang D, Yang LJ, Biochimica Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1/1/2016
• Irisin Controls Growth, Intracellular Ca2+ Signals, and Mitochondrial Thermogenesis in Cardiomyoblasts  
  Xie C, Zhang Y, Tran TD, Wang H, Li S, George EV, Zhuang H, Zhang P, Kandel A, Lai Y, Tang D, Reeves WH, Cheng H, Ding Y, Yang LJ, PLoS One, 1/25/2015
• Pancreatic and Duodenal Homeobox Gene 1 (Pdx1) Suppresses hepatic transcription factor 1 alpha (HNF1alpha) Expression during Reprogramming of Human Hepatic Cells into ...  
  Donelan W, Li SW, Wang H, Lu S, Xie C, Tang DQ, Chang LJ, and Yang LJ, American J Translational Research, 1/15/2015
• Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6NODC11bxC1tb Mice  
  Garrigan E, Belkin NS, Seydel F, Han Z, Carter J, McDuffie M, Morel L, Peck AB, Clare-Salzler MJ, Atkinson M, Wasserfall C, Davoodi-Semiromi A, Shi JD, Haskell-Luevano..., Genetic Epigenetics, 1/11/2015
• Irisin Induces Angiogenesis in Human Umbilical Vein Endothelial Cells In Vitro and in Zebrafish Embryos In Vivo via Activation of the ERK Signaling Pathway  
  Wu F, Song H, Zhang Y, Zhang Y, Mu Q, Jiang M, Wang F, Zhang W, Li L, Li H, Wang Y, Zhang M, Li S, Yang LJ, Meng Y, Tang D, PLoS One, 1/4/2015
• Maintenance of autoantibody production in pristane-induced murine lupus  
  Han S, Zhuang H, Xu Y, Lee P, Li Y, Wilson JC, Vidal O, Choi HS, Sun Y, Yang LJ, and Reeves WH, Arthritis Research Therapy, 1/1/2015
• Mechanisms of autoantibody production in systemic lupus erythematosus  
  Han S, Zhuang H, Shumyak S, Yang LJ, Reeves WH, Frontiers Immunology, 1/1/2015
• Animal models of interferon signature positive lupus  
  Zhuang H, Szeto C, Han S, Yang LJ, and Reeves WH, Frontiers Immunology, 1/1/2015
• Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis  
  Cho J, Seo J, Lim CH, Yang LJ, Shiratsuchi T, Lee MH, Chowdhury RR, Kasahara H, Kim JS, Oh SP, Lee YJ, Terada N, Cell Death Differentiation, 1/1/2015
• Irisin Promotes Human Umbilical Vein Endothelial Cell Proliferation through the ERK Signaling Pathway and Partly Suppresses High Glucose-Induced Apoptosis  
  Song H, Wu F, Zhang Y, Zhang YZ, Wang F, Jiang M, Wang Z, Zhang MX, Li SW, Yang LJ, Wang XL, Cui T, Tang D, PLoS One, 1/22/2014
• Histamine-induced Ca2+ signaling is mediated by TRPM4 channels in human adipose-derived stem cells  
  Tran TD, Zolochevska O, Figueiredo ML, Wang H, Yang LJ, Gimble JM, Yao S, Cheng H, Biochemistry Journal, 1/1/2014
• High level expression, efficient purification, and bioactivity of recombinant human metallothionein 3 (rhMT3) from methylotrophic yeast Pichia pastoris  
  Wu Q, Li B, Wu F, Yang LJ, Li SW, Li H, Wu D, Cui T, Tang D, Protein Expression & Purification, 1/1/2014
• Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling  
  Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, Qi L, Zhang M, Wang X, Cui T, Yang LJ, Tang D, Diabetes, 1/1/2014
• TLR7/TNFalpha-mediated bone marrow damage in systemic lupus erythematosus  
  Zhuang H, Han S, Xu Y, Wang H, Li Y, Yang LJ, and Reeves WH, Arthritis & Rheumatism, 1/1/2014
• Genetically reprogrammed, liver-derived insulin-producing cells are glucose-responsive, but susceptible to autoimmune destruction in settings of type 1 diabetes  
  Tang DQ, Lu S, Koya V, Qian K, Sun Y, Wang Q, Wang H, Li SW, Zhang C, Hansen B, Atkinson M, Phillips IM, and Yang LJ, American Journal of Translational Research, 1/28/2013
• The Novel Autoantigens in Type 1 Diabetes  
  Han S, Donelan W, Wang H, Reeves W, and Yang LJ, American Journal of Translational Research, 1/24/2013
• Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells  
  Weinstein JS, Delano MJ, Kelly-Scumpia KM, DC Nacionales DC, Li Y, Lee PY, Scumpia PO, Yang LJ, Sobel E, Moldawer LL, and Reeves WH, The Journal of Immunology, 1/15/2013
• "Transient Receptor Potential Melastatin 4 channel controls calcium signals and dental follicle stem cell differentiation"  
  Nelson P, Tran TDN, Zhang H, Zolochevska O, Figueiredo M, Feng JM, Gutierrez DL, Xiao R, Yao S, Penn A, Yang LJ, and Cheng H, Stem Cells, 1/1/2013
• miR-375 regulation of CIP2A controls oral cancer cell proliferation and survival  
  Jung HM, Wang H, Rushi S, Patel, BL. Phillips WC, Reinhold DM, Chang LJ, Yang LJ, and Chan E, Molecular Biology of the Cell, 1/1/2013
• Direct Reprogramming of Fibroblasts to Myocytes via Bacterial Injection of MyoD Protein  
  Bichsel C, Neeld D, Hamazaki T, Chang LJ, Yang LJ, Terada N, and Jin S, Cellular Reprogramming, 1/1/2013
• Novel detection of pancreatic and duodenal homeobox 1 autoantibodies (PAA) in human sera using luciferase immunoprecipitation systems (LIPS) assay  
  Donelan W, Wang H, Li SW, Pittman D, Li Y, Han S, Sun Y, Carter C, Atkinson MA, Reeves WH, Winter WE, and Yang LJ, Int J Clin Exp Pathol, 1/1/2013
• High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pi...  
  Li H, Hui X, Yang S, Hu X, Tang X, Li P, Li S, Yang L, Jin S, Wang Y, Xu A, Wu D, Protein Expression & Purification, 1/1/2013
• Join now to see all

Books/Book Chapters

• "Systemic Lupus Erythematosus (SLE)" 
  Chapter: "Origins of antinuclear antibodies." 
  Page 213 - 233Reeves WH, Y Xu, H Zhuang, Y Li, and Yang LJEditors: RG Lahita, G Tsokos, J Buyon, and T Koike.Academic Press, LondonEdition 5th,2011
• "Type 1 Diabetes / Book 1" 
  Chapter: "Autoantigen-Specific Immunotherapy" 
  Page 425 - 452Suhong Han, William Donelan, Westley Reeves, and Li-Jun YangInTech2011
• Introduction to Clinical Immunology 
  Chapter: Autoimmunity 
  Page 91 - 118Zhuang H, M Kosboth, J Sipos, M Satoh, Yang LJ, and WH ReevesEditors: J Zabriskie.Cambridge University Press2009
• Progress in Stem Cell Research 
  Chapter: The many faces of adult stem cell-derived, in vitro-generated insulin-producing islet-like cells for the treatment of type 1 diabetes. 
  Peck AB, Petersen B, Ramiya V and Yang LJEditors: Markino M.Nova Science Publishers, Inc., NY2006
• Regulation of Hepatic Function 
  Chapter: Mechanism of receptor-mediated Ca2+ entry into rat hepatocytes. 
  Page 276 - 289Williamson, JR and Yang LJMunksgard Int. Publ.1991
• Biological Signal Transduction 
  Chapter: Epidermal growth factor mediated signal transduction in rat hepatocytes. 
  Page 511 - 525Yang LJ, Baffy G., Rhee SG and Williamson JREditors: K.Wirtz.Springer Verlag, New York1991
• Join now to see all

Lectures

• "Irisin, burning fat to fight obesity." 
  1/21/2016
• "Pdx1 and protein therapy in treating diabetes." 
  Haikou, Hainan, China - 1/11/2013
• "Diabetes and Cancer: Is there a connection?" 
  Hunan Providence, China - 1/12/2012
• "Directed reprogramming hepatic stem cells into pancreatic beta cells." 
  Beijing, China - 1/11/2011
• "Stem cells and cell therapy for diabetes." 
  Tianjin, China - 1/3/2011
• "Role of Pdx1 in regenerative medicine for treatment of diabetes." 
  Winston-Salem, NC - 1/23/2010
• "Role of Pdx1 in pancreatic beta cell regeneration." 
  1/19/2010
• "Generation of Induced Pluripotent Stem Cells Using Lentiviral Vectors Encoding Reprogramming Factors plus Cell Growth and Survival Regulatory Genes as well as Several... 
  Salerno, Italy - 1/17/2010
• "Pdx1- A novel pancreatic beta cell-specific autoantigen." 
  1/16/2010
• "Liver cell reprogramming with protein transduction." 
  Tel Aviv, Israel - 1/5/2010
• "Roles of Pdx1 protein in treatment of type 1 diabetes." 
  Cairo, Egypt - 1/5/2010
• "Reprogramming bone marrow stem cells into insulin-producing cells for cell replacement therapy." 
  Cairo, Egypt - 1/4/2010
• "Cell fate and reprogramming with protein transduction technology" 
  Wudang, China - 1/30/2009
• "Reprogramming hepatocytes into beta cells." 
  1/15/2009
• "Penetrating Protein Therapy for treatment of Diabetes" 
  Gainesville, FL - 1/3/2008
• "Generation of Beta-Cell Surrogates for a Cure of Diabetes" 
  Cleveland, OH - 1/17/2006
• "Stem cell and gene therapy of Type I diabetes." 
  Gainesville, FL - 1/29/2005
• "Beta-cell surrogates and type 1 diabetes." 
  Tampa, FL - 1/28/2005
• "Liver cell transdifferentiation into insulin-producing cells by genetic modification." 
  1/13/2005
• "Liver to Endocrine Pancreas Transdifferentiation" 
  San Diego, CA - 1/9/2005
• "Transdifferentiation of bone marrow-derived stem cells into functional insulin-producing cells." 
  Somerville, NJ - 1/23/2004
• "Generating beta-cell surrogates for treatment of type 1 diabetes." 
  Philadelphia, PA - 1/22/2004
• "From bone marrow to functional insulin-producing cells." 
  Baltimore, MD - 1/22/2004
• "Toward generating Beta-Cell surrogate from adult stem cells" 
  1/20/2004
• "Dendritic cell and T-cell therapy targeting multiple myeloma." 
  1/19/2004
• Join now to see all