Leslie Jane Crofford MD

Rheumatology•Nashville, TN

Myositis, Scleroderma & Related, Vasculitis

Professor of Medicine, Vanderbilt University

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3601 21st Ave SNashville, TN 37232
Phone+1 615-322-3000

Education & Training

National Institutes of Health Clinical CenterFellowship, Rheumatology, 1989 - 1992
Clinical Center at the National Institutes of HealthResidency, Internal Medicine, 1987 - 1989
Washington University/B-JH/SLCH ConsortiumResidency, Internal Medicine, 1984 - 1987
University of Tennessee Health Science Center College of MedicineClass of 1984

Certifications & Licensure

KY State Medical License 2004 - 2026
TN State Medical License 2013 - 2026
AL State Medical License 2020 - 2025
MI State Medical License 1993 - 2006
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Rheumatology

Awards, Honors, & Recognition

Nashville Lifestyles Magazine Castle Connolly, 2014
America's Top Doctors Castle Connolly, 2002-2014
Fellow (FACR) American College of Rheumatology

Clinical Trials

Scleroderma: Cyclophosphamide or Transplantation Start of enrollment: 2005 Jun 01
Completed
Phase 2, Phase 3
SCOT Scleroderma Treatment Alternative Registry (STAR Registry) Start of enrollment: 2005 Jun 01
Completed
D-Ribose for Fatigue in Subjects With Fibromyalgia Start of enrollment: 2011 May 01
Completed
Phase 2
Fibromyalgia Activity Study With Transcutaneous Electrical Nerve Stimulation (FAST) Start of enrollment: 2013 Sep 30
Completed
Not Applicable
Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis Start of enrollment: 2014 Oct 01
Completed
Phase 2
Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus Start of enrollment: 2018 Aug 23
Recruiting
Phase 2
Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial Start of enrollment: 2021 Jan 22
ACTIVE_NOT_RECRUITING
PHASE3
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Publications & Presentations

PubMed

Collection of Patient-Reported Outcome Measures in Rural and Underserved Populations.
Andrea Cheville, Crystal L Patil, Andrew D Boyd, Leslie J Crofford, Dana Dailey
Applied Clinical Informatics. 2025-03-01
Psoriatic arthritis phenotype clusters and their association with treatment response: a real-world longitudinal cohort study from the psoriatic arthritis research cons...
Paras Karmacharya, Leslie J Crofford, Daniel W Byrne, Alisa Stephens-Shields, M Elaine Husni
Annals of the Rheumatic Diseases. 2025-02-01
Impact of electronic health record updates and changes on the delivery and monitoring of interventions in embedded pragmatic clinical trials.
Keith A Marsolo, Andrea Cheville, Edward R Melnick, Jeffrey G Jarvik, Gregory E Simon
Contemporary Clinical Trials. 2025-01-01

Journal Articles

Physical Activity Is Related to Function and Fatigue but Not Pain in Women with Fibromyalgia: Baseline Analyses from the Fibromyalgia Activity Study with TENS (FAST)
Leslie Crofford, MD, BioMed Central
Interstitial Pneumonia with Autoimmune Features: An Emerging Challenge at the Intersection of Rheumatology and Pulmonology
Robert J Lentz, Peggy L Kendall, Leslie J Crofford, James J Tolle, Adam Guttentag, Timothy S Blackwell, Joyce E Johnson, Erin M Wilfong, Jonathan A Kropski, Arthritis & Rheumatology

Press Mentions

Fall 2021’s Awards, Appointments & Announcements in RheumatologyOctober 13th, 2021
New Clinician Spotlight: Jason SpringerApril 20th, 2021
An Exciting Pipeline of Neurotech Treatments for FibromyalgiaMarch 3rd, 2021
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Grant Support

Interdisciplinary Training in Rheumatic DiseasesVANDERBILT UNIVERSITY2010–2026
Fibromyalgia TENS in Physical Therapy Study (TIPS):an embedded pragmatic clinical trialUNIVERSITY OF IOWA2019–2025
Microsomal Prostaglandin E Synthase In Rheumatoid ArthritisNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2010–2012
Contribution Of Altered Muscle Hemodynamics To Fatigability In Older Persons WithNational Institute On Aging2009–2010
Prostaglandin E Synthase In Rheumatoid ArthritisNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004–2008
RIMNational Center For Research Resources2007
Evaluation Of Sleep Dysfunction In FibromyalgiaNational Center For Research Resources2004–2005
Neuroendocrine Function In FibromyalgiaNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004
Cerebrospinal Fluid Neuropeptides In FibromyalgiaNational Center For Research Resources2004
Neuroendocrine Function In FibromyalgiaNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2000–2004
Training Of Arthritis Research ScientistsNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2000–2003
Synoviocyte Rho-Type Gtpases In Cartilage DestructionNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2000–2002
HPA Axis Dysregulation In FibromyalgiaNational Center For Research Resources1996–2002
HPA Axis Dysregulation In FibromyalgiaNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1998–2000
Mechanism Of Immune Modulation By Corticotropin ReleaseNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1994–1998
Interactions Between The Nervous And Immune Systems In Inflammatory ArthritisNational Center For Research Resources1997
HPA Axis Dysregulaton In FibromyalgiaNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1995–1996