LeonardA.ZwellingMD

PubMed

• 108 citations
  Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage an...
  Yves Pommier, Jon Minford, Ronald E. Schwartz, Leonard A. Zwelling, Kurt W. Kohn
  Biochemistry. 1985-11-01
• 160 citations
  Correlations between intercalator-induced DNA strand breaks and sister chromatid exchanges, mutations, and cytotoxicity in Chinese hamster cells.
  Yves Pommier, Leonard A. Zwelling, C. S. Kao-Shan, Jacqueline Whang-Peng, Matthews O. Bradley
  Cancer Research. 1985-07-01
• 338 citations
  Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino) methanesulfon-m...
  Leonard A. Zwelling, Stephen Michaels, Leonard C. Erickson, Richard S. Ungerleider, Margaret Nichols
  Biochemistry. 1981-11-10

Journal Articles

• "Health care controversy blown out of proportion"  
  Zwelling, LA, Houston Chronicle, 7/19/2014
• "Women, Non-Smokers and Lung Cancer Screening Cost" Letter to the Editor  
  Zwelling, L, Wall Street Journal, 6/26/2014
• "Rebbe –The Life and Teachings of Menachem M Schneerson", Book Review  
  Zwelling, L, The Jewish Herald Voice, 6/12/2014
• "Drug prices", Letter to the Editor  
  Zwelling, L, Houston Chronicle, 5/13/2014
• "Dealing with health care costs: controls needed", Letter to the Editor  
  Zwelling, L, Houston Chronicle, 4/26/2014
• First, Nobody Dies' is necessary cancer creed  
  Jones, L and Zwelling, L, Houston Chronicle, 4/9/2014
• "Medicine Should Refocus on Patients and Physicians", Letter to the Editor  
  Zwelling, L, Wall Street Journal, 3/17/2014
• "Obamacare not enough as long as inequity persists: A perfect union will start with a healthier one"  
  Zwelling, L, Houston Chronicle, 3/16/2014
• "Testing medical devices, placebo surgery and ethics", Letter to the Editor  
  Zwelling, L, Wall Street Journal, 2/27/2014
• "ObamaCare: Why Should We Care?"  
  Zwelling LA and Kantarjian, H, J Oncology Practice, 1/1/2014
• "Reform efforts will fail when decisions are driven by profits"  
  Zwelling, L, Houston Chronicle, 12/15/2013
• "Most ‘providers’ don’t have the old first name—doctor"  
  Zwelling, L, Houston Chronicle, 12/1/2013
• "Budget Needed", Letter to the Editor  
  Zwelling, L, Houston Chronicle, 10/28/2013
• "Research, treatments for cancer fall short"  
  Zwelling, LA, Houston Chronicle, 9/17/2013
• "US Should Set Priorities for Health Care Spending"  
  Zwelling, LA, Houston Chronicle, 8/14/2013
• "US Needs Universal Health Care"  
  Zwelling LA and Kantarjian H, Houston Chronicle, 6/30/2013
• "Sunday Dialogue: Treating Mental Illness", Letter to the Editor  
  Zwelling, LA, NY Times, 5/26/2013
• "A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic"  
  Mobley A, Linder SK, Braeuer R, Ellis L, and Zwelling L, PLOS ONE, 5/15/2013
• "ObamaCare Shock, a Stop in the Road to Single-Payer", Letter to the Editor  
  Zwelling, LA, The Wall Street Journal, 5/3/2013
• "Doctor Nab in Dubai and Donations", Letter to the Editor  
  Zwelling, LA, Kurzrock, R, Cohen, PR, Wall Street Journal, 3/19/2013
• "Repositioning academic medicine: changes in health care"  
  Zwelling, LA, Houston Chronicle, 3/9/2013
• "How to make drugs cheaper"  
  Kantarjian, H, Fojo, T and Zwelling L, Ft. Worth Star-Telegram; Washington Post, 2/28/2013
• "Interlocking tragedies: Armstrong and CPRIT"  
  Zwelling, LA, Houston Chronicle, 2/13/2013
• Letter to the Editor, on opinion piece by Winkler: “CPRIT ignoring business”  
  Zwelling, LA, Austin-American Statesman, 2/3/2013
• "It’s time to price drugs by their value to patients"  
  Kantarjian, H and Zwelling, LA, Houston Chronicle, 1/13/2013
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Books/Book Chapters

• 20 Literacy Strategies to Meet the Common Core 
  Chapter: “Time for some innovative thinking in the war on cancer” 
  Zwelling LAEditors: McEwan-Adkins and Burnett.Solution Tree Press2013
• Cancer Clinical Trials: Proactive Strategies. 
  Chapter: Strategies for the Administration of a Clinical Trials Infrastructure: Lessons from a Comprehensive Cancer Center. 
  Page 241 - 274Zwelling, LA and Brunelli, CAEditors: Leong, SPL.Springer, New York, NY2007
• Methods in Molecular Biology Vol. 95: DNA Topoisomerase Protocols. Part II: Enzymology and Drugs. 
  Chapter: Drug-Induced Cytotoxicity in Tissue Culture. 
  Page 205 - 213Herzog, CE and Zwelling, LAEditors: Osheroff, N and Bjornsti MA.Humana Press, Totowa, NJ2001
• Progress in Anti-Cancer Chemotherapy. 
  Chapter: Protecting human subjects from risk in the performance of clinical research and the informed consent process. 
  Page 7 - 15Buzdar, A.U., Brunelli, C.B. and Zwelling, L.A.Springer-Verlag, France1999
• Frontiers in Pharmacology: Cancer Chemotherapy. 
  Chapter: Resistance to topoisomerase II-directed agents. 
  Page 200 - 213Ellis, A. L. and Zwelling, L. A.Editors: Hickman, J. A. and Tritton, T..Blackwell Scientific Publishers Ltd., Oxford, England1993
• Cancer Chemotherapy and Biological Response Modifiers 
  Chapter: Cisplatin and new platinum analogs. 
  Page 64 - 72Zwelling, L.A.Editors: Pinedo, H.M., Chabner, B.A., and Longo, D..1988
• DNA: Protein Interactions and Gene Regulation 
  Chapter: Topoisomerase II-DNA complexes: novel targets of antineoplastic drug action. 
  Page 183 - 199Zwelling, L.A.Editors: Thompson, E.B. and Papaconstantinou, J..University of Texas Press1987
• Occult Nodal Metastasis in Solid Carcinomata, Cancer Research Monographs, Vol. 5 
  Chapter: The stabilization of topoisomerase II-DNA complexes as a mechanism of antineoplastic drug action. 
  Page 73 - 82Zwelling, L.A., Silberman, L. and Estey EEditors: Moloy, P.J., and Nicholson, G.L..Praeger1987
• Cancer Chemotherapy 
  Chapter: Cisplatin and new platinum analogs. 
  Page 97 - 116Zwelling, L.A.Editors: Pinedo, H.M. and Chabner, B.A..1986
• Recent Developments in Cancer Chemotherapy. 
  Chapter: Intercalator-induced protein-associated DNA strand breaks in mammalian cells. 
  Page 181 - 205Zwelling, L.A., Pommier, Y., Kerrigan, D., and Mattern, M.R.Editors: Glazer, R.I..CRC Press1984
• Platinum, Gold and Other Metal Chemotherapeutic Agents (American Chemical Society Symposium Series) 
  Chapter: The biological consequences of Pt-DNA crosslinks in mammalian cells. 
  Page 27 - 49Zwelling, L.A.Editors: Lippard, S.J..1983
• Advances in Enzyme Regulation. 
  Chapter: Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity. 
  Page 271 - 303Cooney, D.A., Jayaram, H.N., Glazer, R.I., Kelley, J.A., Marquex, V.E., Gebeyehu, G., Van Cott, A.C., Zwelling, L.A., and Johns, D.G.Editors: Weber, G..Pergamon Press1983
• International Symposium on Anthracycline Antibiotics in Cancer Therapy. 
  Chapter: Consequences of DNA intercalation: protein-associated DNA strand breaks. 
  Page 86 - 96Kohn, K.W. and Zwelling, L.A.Editors: Muggia, F.M., Young, C.W. and Carter, S.K..Martinus, Nishoff1982
• Pharmacologic Principles of Cancer Treatment. 
  Chapter: Platinum complexes. 
  Page 309 - 339Zwelling, L.A. and Kohn, K.W.Editors: Chabner, B.A..W.B. Saunders1982
• DNA Repair: A Laboratory Manual of Research Techniques. 
  Chapter: Measurements of strand breaks and crosslinks in DNA by alkaline elution. 
  Page 379 - 401Kohn, K.W., Kwig, R.A.G., Erickson, L.C., and Zwelling, L.A.Editors: Friedberg, E.C. and Hanawalt, P.C..Marcel Dekker1981
• Cisplatin-Current Status and New Developments. Bristol Laboratories Symposium 
  Chapter: Effects of cisplatin on DNA and possible relationships to cytotoxicity and mutagenicity in mammalian cells. 
  Page 21 - 35Zwelling, L.A. and Kohn, K.W.Editors: Prestayko, A.W., Crooke, S.T., and Carter, S.K..New York, NY1980
• Short Term Tests for Prescreening of Potential Carcinogens. 
  Chapter: Measurements of DNA damage in mammalian cells by alkaline elution. 
  Page 11 - 19Kohn, K.W., Ewig, R.A.G., Erickson, L.C., Zwelling, L.A., Ross, W.E., and Cohen, L.C.Editors: Santi, L., and Parodi, S..Instituto Scientifico Per Lo Studio E La Cura Dei Tumor, Genova, Italy1979
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Lectures

• Invited Speaker- “Red Kool-Aid, Blue Kool-Aid” 
  Baylor College of Medicine - 11/7/2014
• Invited Speaker- “Red, Sick and Blue” 
  Houston, TX - 4/22/2014
• Invited Speaker- “Red, Blue and Sick” 
  Houston, TX - 1/14/2014
• Invited Speaker- “Bleeding Red, Bleeding Blue” 
  Houston, TX - 6/22/2013
• Invited Speaker- “Conflict of Interest in Academia-Straining the Public’s Trust” 
  The University of Texas School of Medicine, Houston, TX - 4/3/2013
• Invited panelist-All Houston Emergency Medicine Conference 
  2/21/2013
• Invited Speaker- 2nd Year course in global health and health policy-lecture and lead small group discussion. 
  Duke University Medical School - 12/13/2012
• Southern Medical Association: 2012 Healthcare Summit 
  Southern Medical Association(SMA), Nashville, Tennessee - 11/16/2012
• Invited Speaker- “Red Kool-Aid, Blue Kool-Aid: Health Care Reform After the Election” 
  Nashville, TN - 11/16/2012
• Invited Speaker- “The ACA and Healthcare Reform” 
  Rice University - 9/15/2012
• Invited Speaker- “The Business of Affordable Healthcare” 
  Houston, TX - 9/5/2012
• Invited Speaker- “Houston, Do We Have a Problem?: Retractions, Mistakes, and Other Causes of Non-reproducible Results“ 
  MD Anderson Cancer Center - 8/2/2012
• Invited Speaker- “Health Care Reform” 
  Houston, TX - 7/12/2012
• Invited Speaker- “Red Kool-Aid, Blue Kool-Aid: Delivering Quality Healthcare Despite Morons and Crooks on Capitol Hill and the Nation’s Premier Cancer Hospital”. 
  7/9/2012
• Invited Speaker- “Red Kool, Blue Kool-Aid”; Health Care Reform and the 4 P’s” 
  The University of Houston School of Law - 4/23/2012
• Invited Speaker- “Red Kool-Aid, Blue Kool-Aid: Health Care Reform 101 for Oncologists” 
  Talkeetna, AK - 3/31/2012
• Invited Speaker- “Red Kool-Aid, Blue Kool-Aid: Health Care Reform Update” 
  Houston, TX - 3/30/2012
• Invited Speaker- “Red Kool-Aid, Blue Kool-Aid: Policy, Process, Politics and Personalities that Led to the Passage of the Health Care Bill (PPACA 2010). What It Tea... 
  Washington, DC - 3/19/2012
• Invited panelist-Health Care Eeform-UT Health 
  2/15/2012
• Invited Speaker- “Red Kool Aid, Blue Kool Aid: A Doctor’s Odyssey on Capitol Hill During the Passage of the Patient Protection and Affordable Care Act: What Will It ... 
  MD Anderson Cancer Center - 10/21/2011
• Invited Speaker- “Code Red, Code Blue: How Understanding policy, process, politics and personalities can lead medicine through its current crisis” 
  University College Dublin, Ireland - 9/9/2011
• Invited Speaker- “Red Kool-Aid, Blue Kool-Aid: Part 2: What Now in Health Care?” 
  Houston, TX - 7/3/2011
• Invited Speaker-“Red Kool Aid, Blue Kool Aid: A Doctor’s Odyssey on Capitol Hill” 
  5/17/2011
• Invited Speaker- -“Red Kool Aid, Blue Kool Aid: A Doctor’s Odyssey on Capitol Hill” 
  UT Houston School of Medicine - 3/17/2011
• Invited Speaker- “Healthcare Reform: Diagnosis and Prognosis” 
  George McMillan Fleming Center for Healthcare Management, UT Health School of Public Health - 1/27/2011
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Other

• "The Affordable Care Act Is Less a Bill Than It Is a Deal" 
  Zwelling, L, American Association of Pharmaceutical Sciences Blog
  http://aapsblog.aaps.org/2013/06/04/the-affordable-care-act-is-less-a-bill-than-it-is-a-deal/
  6/4/2013
• "Making cancer drugs less expensive" 
  Kantarjian, H, Fojo, T and Zwelling L
  http://www.star-telegram.com/2013/02/28/4652040/setting-a-just-price-for-cancer.html
  1/1/2013
• "Adolescents and Young Adults: Bringing A Neglected Group Into Cancer Research" 
  Zwelling LA, Kleinerman E, Health Affairs Blog
  http://healthaffairs.org/blog/2012/01/13/adolescents-and-young-adults-bringing-a-neglected-group-int
  1/13/2012
• "Put health care in good hands". Special Contributor. 
  Zwelling, L. A., Austin-American Statesman
  http://www.statesman.com/opinion/put-health-care-in-good-hands-2005104.html
  11/30/2011
• Are we too close to cancer? 
  Zwelling, L. A., Statesman.com, Special contributor to the Austin American Statesman
  http://www.statesman.com/opinion/zwelling-are-we-too-close-to-cancer-1638742.html
  7/22/2011
• Comparative Effectiveness Reseaerch: How Can It Change Practice? 
  Zwelling, L. A., Health Affairs Blog
  http://healthaffairs.org/blog/2011/04/18/comparative-effectiveness-research-how-can-it-change-practi
  4/18/2011
• Initial Host-M. D. Anderson Cancer Newsline Podcast 
  Zwelling, LA
  8/1/2008
• Guest Host-Patient Power-Brain Tumors with Dr. Ray Sawaya, 
  Zwelling, LA, Webcast-M.D. Anderson
  7/24/2007
• Invited Speaker – Houston/Galveston National Youth Leadership Forum on Medicine 
  Zwelling, LA
  7/23/2007
• Radio program-America Talks Health -Weekly reports for M.D.Anderson 
  Zwelling, LA
  9/1/1999
• Anti-trypanosomal activity of platinum coordination compounds, #4, 532, 122 (Patent) 
  Wysor, M.S. and Zwelling, L.A.
  7/30/1985
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