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Office
4401 Penn Ave.
Division Of Infectious Diseases
Pittsburgh, PA 15224Phone+1 412-692-5930Fax+1 412-692-5565
Education & Training
- U Arkansas1990 - 1993
- UAMS-AHECChief Residency, 1987 - 1990
- University of Arkansas For Medical Sciences College of MedicineClass of 1987
- University of ArkansasBA, Chemistry, Magna cum laude, 1979 - 1983
Certifications & Licensure
- NC State Medical License 2013 - 2025
- AR State Medical License 1987 - 2018
- PA State Medical License 2007 - 2014
- American Board of Pediatrics Pediatric Infectious Diseases
Awards, Honors, & Recognition
- General Microbiology – Chair American Society for Microbiology, Section D, 2003
- President Southern Society of Pediatric Research, 2001
- Pres-elect Southern Society of Pediatric Research, 2000
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Publications & Presentations
PubMed
- 19 citationsA Chlamydia -Specific TCR-Transgenic Mouse Demonstrates Th1 Polyfunctionality with Enhanced Effector Function.Taylor B. Poston, Yanyan Qu, Jenna Girardi, Catherine M. O'Connell, Lauren C. Frazer
Journal of Immunology. 2017-08-30 - 43 citationsStatus of vaccine research and development of vaccines for Chlamydia trachomatis infection.Taylor B. Poston, Sami L Gottlieb, Toni Darville
Vaccine. 2017-01-19 - 94 citationsChlamydia trachomatis infections in neonates and young childrenToni Darville
Seminars in Pediatric Infectious Diseases. 2005-10-01
Journal Articles
- Plasmid-deficient Chlamydia muridarum fail to induce immune pathology and protect against oviduct disease.O’Connell CM, Ingalls RR, Andrews CW Jr, Scurlock AM, Darville T, J Immunol 2007 Sep 15;179(6):4027-34. PMID: 17785841
- Characterization of chlamydial genital infection resulting from sexual transmission from male to female guinea pigs and determination of infectious dose.Rank RJ, Bowlin AK, Reed RL, Darville T, Infect Immun2003; 71(11):6148-6154
- Toll-like receptor-2, but not toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection.Darville T, O’Neill JM, Andrews CW, Jr., Nagarajan UM, Stahl L, and Ojcius DM, J Immunol2003; 171:6187-6197
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Books/Book Chapters
Abstracts/Posters
- NK cells inability to produce IFN gamma in MyD88-/- mice contributes to the delayed clearance of Chlamydia muridarum primary genital infection.Nagarajan U.M, Sikes JD, Prantner D, Goodwin A, and Darville T, American Association of Immunology Meeting, Seattle, Washington
- Differential dendritic cell responses in strains of mice with different outcomes of chlamydial genital tract infection.Johnson J and Darville T, 2nd Annual Chlamydia Basic Research Society Meeting, Indianapolis, Indiana
- The lack of pathology in mice infected with plasmid-deficient strains of Chlamydia muridarum is due to an absence of TLR2-dependent signaling.Darville T, R Ingalls, CW Andrews, Jr., CM O’Connell, Society of Leukocyte Biology, San Antonio, Texas
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Other
- Intervention strategies for human immunodeficiency virus infected children poorly adherent with antiretroviral therapy; non-adherence as medical neglect.Roberts GM, Wheeler JG, Tucker NC, Hackler C, Young K, Maples HD, and Darville T, Pediatrics 2004;114:e346-e353
http://www.pediatrics.org/cgi/content/full/114/3/e346
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