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Lee Darville, MD, Pediatric Infectious Disease, Pittsburgh, PA

LeeAntoinetteDarvilleMD

Pediatric Infectious Disease Pittsburgh, PA

Professor, Pediatrics, University of Pittsburgh School of Medicine

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  • Office

    4401 Penn Ave.
    Division Of Infectious Diseases
    Pittsburgh, PA 15224
    Phone+1 412-692-5930
    Fax+1 412-692-5565

Education & Training

  • U Arkansas
    U Arkansas1990 - 1993
  • UAMS-AHEC
    UAMS-AHECChief Residency, 1987 - 1990
  • University of Arkansas For Medical Sciences College of Medicine
    University of Arkansas For Medical Sciences College of MedicineClass of 1987
  • University of Arkansas
    University of ArkansasBA, Chemistry, Magna cum laude, 1979 - 1983

Certifications & Licensure

  • NC State Medical License
    NC State Medical License 2013 - 2025
  • AR State Medical License
    AR State Medical License 1987 - 2018
  • PA State Medical License
    PA State Medical License 2007 - 2014
  • American Board of Pediatrics Pediatric Infectious Diseases

Awards, Honors, & Recognition

  • General Microbiology – Chair American Society for Microbiology, Section D, 2003
  • President Southern Society of Pediatric Research, 2001
  • Pres-elect Southern Society of Pediatric Research, 2000
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Publications & Presentations

PubMed

Journal Articles

  • Plasmid-deficient Chlamydia muridarum fail to induce immune pathology and protect against oviduct disease.  
    O’Connell CM, Ingalls RR, Andrews CW Jr, Scurlock AM, Darville T, J Immunol 2007 Sep 15;179(6):4027-34. PMID: 17785841
  • Characterization of chlamydial genital infection resulting from sexual transmission from male to female guinea pigs and determination of infectious dose.  
    Rank RJ, Bowlin AK, Reed RL, Darville T, Infect Immun2003; 71(11):6148-6154
  • Toll-like receptor-2, but not toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection.  
    Darville T, O’Neill JM, Andrews CW, Jr., Nagarajan UM, Stahl L, and Ojcius DM, J Immunol2003; 171:6187-6197
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Books/Book Chapters

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Abstracts/Posters

  • NK cells inability to produce IFN gamma in MyD88-/- mice contributes to the delayed clearance of Chlamydia muridarum primary genital infection.
    Nagarajan U.M, Sikes JD, Prantner D, Goodwin A, and Darville T, American Association of Immunology Meeting, Seattle, Washington
  • Differential dendritic cell responses in strains of mice with different outcomes of chlamydial genital tract infection.
    Johnson J and Darville T, 2nd Annual Chlamydia Basic Research Society Meeting, Indianapolis, Indiana
  • The lack of pathology in mice infected with plasmid-deficient strains of Chlamydia muridarum is due to an absence of TLR2-dependent signaling.
    Darville T, R Ingalls, CW Andrews, Jr., CM O’Connell, Society of Leukocyte Biology, San Antonio, Texas
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Other

  • Intervention strategies for human immunodeficiency virus infected children poorly adherent with antiretroviral therapy; non-adherence as medical neglect. 
    Roberts GM, Wheeler JG, Tucker NC, Hackler C, Young K, Maples HD, and Darville T, Pediatrics 2004;114:e346-e353
    http://www.pediatrics.org/cgi/content/full/114/3/e346