LeeK.BrownMD

PubMed

• Targeting Hypercapnia in Chronic Lung Disease and Obesity Hypoventilation: Benefits and Challenges.
  Lee K Brown
  Sleep Medicine Clinics. 2024-06-01
• 1 citations
  Central Sleep Apnea with Heart Failure: Two Bad Bedfellows.
  Shahrokh Javaheri, Winfried J Randerath, Lee K Brown
  Annals of the American Thoracic Society. 2023-03-01
• 1 citations
  Acetazolamide for central sleep apnea: teaching an old drug new tricks?
  Lee K. Brown
  Journal of Clinical Sleep Medicine. 2021-06-01

Journal Articles

• Improving the Affordability of Prescription Medications for People with Chronic Respiratory DiseaseAn Official American Thoracic Society Policy Statement  
  Patel MR, Press VG, Gerald LB, Barnes T, Blake K, Brown LK, Costello RW, Crim C, Forshag M, Gershon AS, Goss CH, Han MK, Lee TA, Sweet S, Gerald JK, Am J Respir Crit Care Med, 1/1/2018
• CON: Persistent Central Sleep Apnea/Hunter Cheyne Stokes Breathing, Despite Best Guideline-based Therapy of Heart Failure with Reduced Ejection Fraction, is Not a Comp...  
  Javaheri S, Brown LK, Khayat R, J Clin Sleep Med, 1/1/2018
• Rebuttal to Naughton  
  Javaheri S, Brown LK, Khayat R, J Clin Sleep Med, 1/1/2018
• Smearing HSC was self-promotion (commentary)  
  Brown LK, Albuquerque Journal, 1/17/2017
• Letter misuses column (letter)  
  Brown LK, Albuquerque Journal, 1/9/2017
• The development of positive airway pressure technology and applicationsFaster than space travel!  
  Brown LK, Javaheri S, Sleep Med Clin, 1/1/2017
• Epidemiology of Sleep-Disordered Breathing and Heart Failure: What Drives What?  
  Dharia SM, Brown LK, Curr Heart Fail Rep, 1/1/2017
• Positive airway device technology past and presentWhat�s in the �Black Box�?  
  Brown LK, Javaheri S, Sleep Med Clin, 1/1/2017
• The high road, the low road, or both: Effects of positive airway pressure route of administration on treatment efficacy for obstructive sleep apnea  
  Cutrufello NJ, Brown LK, Chest, 1/1/2016
• SERVE-HF: More Questions than Answers (commentary)  
  Javaheri S, Brown LK, Randerath W, Khayat R, Chest, 1/1/2016
• Relationships between obstructive sleep apnea and anxiety  
  Diaz SV, Brown LK, Curr Opin Pulm Med, 1/1/2016
• The relationship between Volume Overload in End Stage Renal Disease and Obstructive Sleep Apnea  
  Roumelioti M-E, Brown LK, Unruh ML, Semin Dial, 1/1/2015
• Adaptive Servo-ventilation: Answer to a Sleep Physician�s Dream? (editorial)  
  Brown LK, Chest, 1/1/2015
• Obesity hypoventilation syndrome  
  Brown LK, Curr Sleep Medicine Rep, 1/1/2015
• Central Sleep Apnea in Kidney Disease  
  Dharia SM, Unruh ML, Brown LK, Semin Nephrol, 1/1/2015
• Are We Ready for �Unisomnography�? Commentary on: Masa et alEfficacy of Home Single-Channel Nasal Pressure for Recommending Continuous Positive Airway Pressure Treatme...  
  Brown LK, Sleep, 1/1/2015
• Resistant hypertension in obstructive sleep apnea: is CPAP the next step?  
  Jhamb M, Brown LK, Unruh M, Am J Kidney Dis, 1/1/2014
• Positive airway pressure therapy with adaptive servo-ventilation- Part 1: Operational algorithms  
  Javaheri S, Brown LK, Randerath WJ, Chest, 1/1/2014
• Positive airway pressure therapy with adaptive servo-ventilation- Part 2: Clinical Applications  
  Javaheri S, Brown LK, Randerath WJ, Chest, 1/1/2014
• Fatigue is the best pillow: Sleepiness vsfatigue in sarcoidosis(editorial)  
  Brown LK, Chest, 1/1/2013
• Non-invasive Ventilatory Support in Obesity Hypoventilation Syndrome: Back-up Early and Often? (editorial)  
  Brown LK, Chest, 1/1/2013
• Point: Should board certification in sleep be required to prescribe CPAP therapy on the basis of home testing? Yes  
  Brown LK, Chest, 1/1/2013
• Point: Should board certification in sleep be required to prescribe CPAP therapy on the basis of home testing? YesRebuttal from DrBrown  
  Brown LK, Chest, 1/1/2013
• Recognition and treatment of obstructive sleep apnea  
  Dharia S, Brown LK, Unruh ML, Semin Dialysis, 1/1/2013
• The Effects of Body Fat Distribution on Obstructive Sleep Apnea: Are Older and Younger Adults The Same? (editorial)  
  Brown LK, Sleep, 1/1/2013
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Books/Book Chapters

• Chronic Renal Disease. 
  Chapter: Sleep Disorders in Chronic Kidney Disease. 
  Page 332 - 349Dharia S, Brown LK, Unruh MEditors: Kimmel PL, Rosenberg ME.Academic Press, San Diego, CA2015
• Primary Care Sleep Medicine a Practical Guide 
  Chapter: Central Sleep Apnea and Obesity Hypoventilation Syndromes. 
  Dharia S, Brown LKEditors: Pagel JF, Pandi-Perumal.Springer, Philadelphia, PAEdition 2nd,2014
• Encyclopedia of Sleep. 
  Chapter: Sleep related idiopathic non-obstructive alveolar hypoventilation. 
  Page 309 - 313Brown LKEditors: Kushida C.Academic Press, London, United Kingdom2013
• Pulmonary and Respiratory Therapy Secrets 
  Chapter: Pulmonary Function Testing. 
  Brown LK, Miller AEditors: Parsons PE, Heffner JH.Hanley & Belfus, Philadelphia, PAEdition 2nd,2002
• Pulmonary and Respiratory Therapy Secrets 
  Chapter: Sleep Apnea Syndromes. 
  Brown LKEditors: Parsons PE, Heffner JH.Hanley & Belfus, Philadelphia, PAEdition 2nd,2002
• Internal Medicine Pearls 
  Chapter: A 45-year-old man with sleepiness, snoring, and disturbed nocturnal sleep 
  Page 75 - 78Guido PS, Brown LKEditors: Sahn SA, Heffner JE.Hanley & Belfus, Philadelphia, PAEdition 2nd,2001
• Internal Medicine Pearls 
  Chapter: A 69-year-old woman complaining of frequent nocturnal awakenings and daytime sleepiness 
  Page 82 - 85Brown LKEditors: Sahn SA, Heffner JE.Hanley & Belfus, Philadelphia, PAEdition 2nd,2001
• Internal Medicine Pearls 
  Chapter: A 19-year-old woman with profound fatigue 
  Page 89 - 91Doggett JW, Brown LKEditors: Sahn SA, Heffner JE.Hanley & Belfus, Philadelphia, PAEdition 2nd,2001
• Saunders Manual of Medical Practice 
  Chapter: Sleep Apnea. 
  Brown LKEditors: Rakel RE.W.B.Saunders, Philadelphia, PAEdition 2nd,2000
• Critical Care Pearls II. 
  Chapter: A 23-Year-Old Obese Man with Cardiopulmonary Failure. 
  Brown LKEditors: Sahn SA, Heffner JE.Hanley & Belfus, Philadelphia, PA1997
• Pulmonary and Respiratory Therapy Secrets. 
  Chapter: Sleep Apnea Syndromes. 
  Brown LKEditors: Parsons PE, Heffner JH.Hanley & Belfus, Philadelphia, PA1997
• Pulmonary and Respiratory Therapy Secrets. 
  Chapter: Pulmonary Function Testing. 
  Brown LK, Miller AEditors: Parsons PE, Heffner JH.Hanley & Belfus, Philadelphia, PA1997
• Saunders Manual of Medical Practice. 
  Chapter: Sleep Apnea. 
  Brown LKEditors: Rakel RE.W.B.Saunders, Philadelphia, PA1996
• The Practice of Thoracic Anesthesia. 
  Chapter: Pulmonary Physiology. 
  Brown LKEditors: Cohen E.J.B.Lippincott, Philadelphia, PA1995
• Surgical Management of Urologic Disease.An Anatomic Approach. 
  Chapter: Preoperative Assessment and Preparation of the Urologic Patient.3.Pulmonary Assessment 
  Brown LKEditors: Droller MJ.Mosby, St.Louis, MO1992
• Proceedings of the 11th World Congress on Sarcoidosis. 
  Chapter: The spectrum of airways obstruction in sarcoidosis. 
  Page 351 - 354Miller A, Teirstein AS, Pilipski M, Brown LKEditors: Grassi C, Rizzo G, Pozzi E.Excerpta Medica, Amsterdam, The Netherlands1988
• Proceedings of the 11th World Congress on Sarcoidosis. 
  Chapter: The Kveim-Siltzbach test in 1987. 
  Page 7 - 18Teirstein AS, Brown LKEditors: Grassi C, Rizzato G, Pozzi E.Excerpta Medica, Amsterdam, The Netherlands1988
• Pulmonary Function Tests.A Guide for the Student and House Officer. 
  Chapter: Surgical Considerations: Effects of Surgery on Lung Function; Preoperative Evaluation 
  Brown LKEditors: Miller A.Grune and Stratton, Orlando, FL1987
• Pulmonary Function Tests.A Guide for the Student and House Officer. 
  Chapter: Full Lung Volumes; Functional Residual Capacity, Residual Volume and Total Lung Capacity 
  Brown LK, Miller AEditors: Miller A.Grune and Stratton, Orlando, FL1987
• Pulmonary Function Tests in Clinical and Occupational Lung Diseases. 
  Chapter: Surgical Considerations: Effects of Surgery on Lung Function; Preoperative Evaluation. 
  Brown LKEditors: Miller A.Grune and Stratton, Orlando, FL1986
• Pulmonary Function Tests in Clinical and Occupational Lung Diseases. 
  Chapter: Static Lung Volumes 
  Brown LKEditors: Miller A.Grune and Stratton, Orlando, FL1986
• Pulmonary Function Tests in Clinical and Occupational Lung Diseases. 
  Chapter: Mechanical Aspects of the Respiratory System 
  Brown LKEditors: Miller A.Grune and Stratton, Orlando, FL1986
• Pulmonary Function Tests in Clinical and Occupational Lung Diseases. 
  Chapter: Mean Transit Time and Moment Analysis 
  Brown LKEditors: Miller A.Grune and Stratton, Orlando, FL1986
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Abstracts/Posters

• A novel smart lighting clinical testbed.
  Gleason JD, Oishi M, Simkulet M, Tuzikas A, Brown LK, Brueck SRJ, Karlicek RF, Conf Proc IEEE Eng Med Biol Soc, 1/1/2017
• Improvement of sleep disordered breathing in a 65 year old woman with multiple sclerosis after discontinuation of fingolimod.
  Bhatia S, Brown LK, Am J Respir Crit Care Med, 1/1/2017
• Increased engagement and adherence in adults with obstructive sleep apnea.
  Rodgers B, Brown LK, Lopez S, Glasser J, Sleep, 1/1/2015
• The use of unattended portable sleep apnea monitoring in the hospital.
  Abouhouli H, Masood S, Brown LK, Ralls F, Sleep; 26th Annual Meeting, Associated Professional Sleep Societies, Boston, MA, 1/1/2012
• Development of an electronic sleep disorders center database.
  Rauch M, Lopez SA, Polnaszek NL, Brown LK, Sleep; 26th Annual Meeting, Associated Professional Sleep Societies, Boston, MA, 1/1/2012
• Osteopontin: a connection between obstructive sleep apnea (OSA) and vascular disease.
  Wells A, Henderson K, Beck A, Brown LK, Gong H, Rauch M, Kanagy NL, Gonzalez Bosc LV, Sleep; 24th Annual Meeting, Associated Professional Sleep Societies, San Antonio, TX, 1/1/2010
• A multi-center randomized trial of adaptive servo-ventilation (ASV) vs.noninvasive (bilevel) positive pressure ventilation (NPPV) treatment for central sleep apnea/Che...
  Gay PC, Morgenthaler TI, Brown LK, Proc Am Thorac Soc; International Conference, American Thoracic Society, San Diego, CA, 1/1/2006
• Prevalence and annual incidence of obstructive sleep apnea in a managed care population with ready access to sleep medicine services.
  Brown LK, Nelson LS, Boxer R, Devanathan S, Doggett J, Gunter MJ, Sleep; 18th Annual Meeting, Associated Professional Sleep Societies, Philadelphia, PA, 1/1/2004
• Charges for healthcare services before and after diagnosis of obstructive sleep apnea: a case control study.
  Brown LK, Boxer R, Nelson LS, Devanathan S, Doggett J, Gunter MJ, Sleep; 18th Annual Meeting, Associated Professional Sleep Societies, Philadelphia, PA, 1/1/2004
• Multilevel and continuous likelihood ratios for pleural fluid (PF) pH in determining need to drain parapneumonic effusions.
  Heffner JE, Heffner JN, Brown LK, Chest; 68th Annual International Scientific Assembly, American College of Chest Physicians, San Diego, CA, 1/1/2002
• Continuous and multilevel likelihood ratios (LR) for pleural fluid (PF) pH in selecting patients with malignant PF for pleurodesis.
  Heffner JE, Heffner JN, Brown LK, Chest; 68th Annual International Scientific Assembly, American College of Chest Physicians, San Diego, CA, 1/1/2002
• Lack of statistical association between antidepressant use and clinical restless legs syndrome in patients referred for insomnia.
  Dedrick DL, Brown LK, Doggett JW, Guido PS, Sleep; 15th Annual Meeting, Associated Professional Sleep Societies, Chicago, IL, 1/1/2001
• Volume assured pressure support in adults with severe obstructive sleep apnea.
  Dedrick DL, Brown LK, Doggett JW, Guido PS, Chest; 66th Annual International Scientific Assembly, American College of Chest Physicians, San Francisco, CA, 1/1/2000
• Oculopharyngeal muscular dystrophy and sleep apnea.
  Dedrick DL, Brown LK, Sleep; 14th Annual Meeting, Associated Professional Sleep Societies, Las Vegas, NV, 1/1/2000
• Ability of a computer system for improving communication of patients' do-not-resuscitate status in an setting.
  Heffner JE, Fracica P, Brown L, Enders K, Barbieri C, Am J Respir Crit Care Med; International Conference, American Thoracic Society, San Francisco, CA, 1/1/1997
• A meta-analysis of tests that discriminate between exudative and transudative pleural effusions.
  Heffner JE, Brown L, Barbieri C, Am J Respir Crit Care Med; International Conference, American Thoracic Society, San Francisco, CA, 1/1/1997
• Comparison of three dental devices for treatment of moderate-severe obstructive sleep apnea syndrome.
  Barthlen GM, Brown LK, Wiland MR, Sadeh JS, Patwari J, Zimmerman M, Sleep Research; 10th Annual Meeting, Association of Professional Sleep Societies, Washington, DC, 1/1/1996
• Subspecialty journals vary in their publication rates for articles on ethics topics.
  Heffner JE, Barbieri C, Brown L, Am J Respir Crit Care Med; International Conference, American Thoracic Society, New Orleans, LA, 1/1/1996
• Use of the Epworth Sleepiness Scale in predicting obstructive sleep apnea in snorers.An ROC analysis.
  Brown LK, Barbieri C, Heffner JE, Sleep Research; 9th Annual Meeting, Association of Professional Sleep Societies, Nashville, TN, 1/1/1995
• Anion-gap metabolic acidosis and outcome in status asthmaticus.
  Brown LK, Barbieri C, Heffner JE, Chest; 61st Annual Scientific Assembly, American College of Chest Physicians, New York, NY, 1/1/1995
• REM-intrusive phenomena in obstructive sleep apnea syndrome: Prevalence and relationship to polysomnographic variables.
  Brown LK, Barbieri C, Heffner JE, Chest; 61st Annual Scientific Assembly, American College of Chest Physicians, New York, NY, 1/1/1995
• Prospective validation of an ARDS score.
  Heffner JE, Brown LK, Barbieri C, Harpel K, Chest; 60th Annual Scientific Assembly, American College of Chest Physicians, New Orleans, LA, 1/1/1994
• ROC analysis of pleural fluid profiles in parapneumonic effusions.
  Heffner JE, Brown LK, Barbieri C, Chest; 60th Annual Scientific Assembly, American College of Chest Physicians, New Orleans, LA, 1/1/1994
• Predictive value of abnormal cardiopulmonary exercise responses in sarcoidosis.
  Zimmerman MI, Sloane MF, Bhuptani A, Miller A, Brown LK, Teirstein AS, XVII World Congress on Diseases of the Chest, Amsterdam, The Netherlands, 1/13/1993
• Elevated intra-abdominal pressure and intrinsic PEEP: Common confounders of occlusion pressure interpretation?
  Nelson JE, Brown LK, Nierman DM, Kalb TH, Oropello JM, Chest; 59th Annual Scientific Assembly, American College of Chest Physicians, Orlando, FL, 1/1/1993
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Lectures

• Why Does Sleep Apnea Matter in Miners. 
  1/13/2019
• Sleep Disordered Breathing in Miners. 
  1/11/2018
• Anatomy and Physiology of the Lung. 
  University of New Mexico, Albuquerque, NM, 2011, 2012, 2016, 2017, 2018 - 1/9/2018
• Reading the Tracing: Measurements, Calculations, and BTPS Correction. 
  University of New Mexico, Albuquerque, NM, 2013, 2014, 2016, 2017, 2018 - 1/9/2018
• Polysomnographic Puzzlers and Sleep Medicine Mysteries: Adult Sleep Disordered Breathing. 
  Los Angeles, CA - 1/23/2016
• Should Mild Sleep Apnea Be Treated in the Presence of Other Cardiovascular Risk Factors? 
  Vancouver, British Columbia, Canada, 2010; Los Angeles, CA, 2016 - 1/23/2016
• Sleep-disordered Breathing without Upper Airway Obstruction: Can�t Breathe or Won�t Breathe? 
  Denver, CO - 1/11/2016
• Opioids: Sleep and Breathing. 
  Albuquerque, NM - 1/10/2016
• CTSC Inpatient Test Bed Project. 
  Bethesda, MD - 1/12/2015
• Adaptive Servo-ventilation. 
  University of New Mexico Health System Sleep Disorders Centers, Albuquerque, NM - 1/11/2015
• Complex Conundrums in Sleep Apnea Care.Presented at: Difficult Cases that Keep You up at Night: Case Based Review of Challenging Clinical Scenarios for the Sleep Medic... 
  Minneapolis, MN - 1/31/2014
• Obesity Hypoventilation Syndrome. 
  University of New Mexico Health Sciences Center, Albuquerque, NM, 2004; University of New Mexico Sch - 1/19/2014
• Panel Discussion: Lighting and Health. 
  Troy, NY - 1/11/2014
• Pathophysiology of Obesity- Hypoventilation syndrome. 
  Chicago, IL - 1/26/2013
• Obstructive Sleep Apnea: Review and Update. 
  Santa Fe, NM - 1/24/2013
• Central Sleep Apnea, Complex Sleep Apnea, and Adaptive Servo-ventilation. 
  University of New Mexico Hospital Sleep Disorders Center, Albuquerque, NM - 1/23/2013
• Recent Developments in the Field of Sleep Disordered Breathing. 
  Santa Fe, NM, 2012; Albuquerque, NM, 2016 - 1/26/2012
• Bilevel PAP Titration Strategies in the Sleep Lab. 
  University of New Mexico Hospital Sleep Disorders Center, Albuquerque, NM - 1/24/2012
• Snoring and Obstructive Sleep Apnea: Anatomy and Pathogenesis. 
  University of New Mexico School of Medicine, Albuquerque, NM - 1/18/2012
• Sleep Deprivation, Fatigue, and You. 
  University of New Mexico School of Medicine, Albuquerque, NM - 1/13/2012
• Complex Sleep Apnea: Does it Exist? Is it Important? How is it Treated? 
  Albuquerque, NM - 1/4/2012
• Using Adaptive Servo-ventilation in the Treatment of Central & Complex Sleep Apnea. 
  Albuquerque, NM - 1/26/2011
• Complex Sleep Apnea: Does it Exist, Is It Important, and How to Treat It. 
  Princeton, NJ - 1/23/2011
• PAP Titration Strategies in the Sleep Lab. 
  Princeton, NJ - 1/23/2011
• Adult Sleep Medicine Cases. 
  Honolulu, HI - 1/22/2011
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Other

• Children�s need for sleep (interview, Colton Shone) 
  Brown LK, KOB Television News
  Albuquerque, NM - 1/5/2018
• Yawn � Sleep disorders take a toll (interview, Tara Gatewood) 
  Brown LK, Koahnic Broadcast Corporation
  Albuquerque, NM - 1/23/2017
• Proposed Changes in UNM-HSC Governance (interview) 
  Brown LK, KOAT 10 PM News
  Albuquerque, NM - 1/13/2016
• Technology�s Effect on Sleep (interview, Erica Zucco) 
  Brown LK, Technology and Our Lives, KOB series
  Albuquerque, NM - 1/4/2016
• Pack the PAC! (guest editorial) 
  Brown LK, GAMA Reports
  1/1/2016
• Daylight Savings Time- How to Make the Adjustment [interview, Judith Jenkins) 
  Brown LK, Morning Show, KKOB Radio
  Albuquerque, NM - 1/10/2014
• Getting Enough Sleep? (interview, Monica Braine) 
  Brown LK, Koahnic Broadcast Corporation
  Albuquerque, NM - 1/3/2014
• Initiation of positive airway pressure therapy for obstructive sleep apnea in adults.(online publication) 
  Dave NB, Brown LK, UpToDate; Wolters Kluwer Health
  Philadelphia, PA - 1/1/2013
• Obstructive Sleep Apnea Syndrome.Pulmonary Medicine & Sleep Disorders.(online publication) 
  Brown LK, CDS: Pulm.Decision Support in Medicine LLC
  Wilmington, DE - 1/1/2013
• Life Outside: Lee K.Brown, M.D., combines medical management with family time and �ham� radio. 
  Brown LK, ATS News
  1/1/2010
• President�s Column: GAMA Annual Membership Fee Could Increase.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• President�s Column: Progress Report.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• President�s Column: Doing Business in the New Millennium.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• President�s Column: Joining Together as a Community of Physicians.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• Physicians and Sleep Deprivation.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• President�s Column: The Year Ahead.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• President�s Column: Caley, We Hardly Knew Ye.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• President�s Column: Of this and that�.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• President�s Column: Changing of the Guard.(editorial) 
  Brown LK, GAMA Reports
  1/1/2008
• Maintenance of Certification and Evidence-based Medicine: Do What We Say, Not What We Do.(editorial) 
  Brown LK, GAMA Reports
  1/1/2007
• Adventures in Washington-land, Part Two.(editorial) 
  Brown LK, GAMA Reports
  1/1/2007
• Combinations in Restraint of Trade: Physicians as Favored Target.(editorial) 
  Brown LK, GAMA Reports
  1/1/2007
• Participation of Albuquerque Physicians in Professional Medical Organizations: Is Volunteerism on Life Support? (editorial) 
  Brown LK, GAMA Reports
  1/1/2007
• I�m From the Government and I�m Here to Help You.(editorial) 
  Brown LK, GAMA Reports
  1/1/2007
• Should Those Who Administer Government Health Programs Know About Health Care Economics? (editorial) 
  Brown LK, GAMA Reports
  1/1/2007
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