LeanneGrobanMD

PubMed

• 11 citations
  Activation of GPR30 improves exercise capacity and skeletal muscle strength in senescent female Fischer344 × Brown Norway rats.
  Hao Wang, Allan K Alencar, Marina Lin, Xuming Sun, Roberto Takashi Sudo
  Biochemical and Biophysical Research Communications. 2016-06-17
• 29 citations
  Activation of GPER ameliorates experimental pulmonary hypertension in male rats.
  Allan K Alencar, Guilherme C Montes, Tadeu L Montagnoli, Ananssa M Silva, Sabrina T. Martinez
  European Journal of Pharmaceutical Sciences. 2017-01-15
• 18 citations
  Cardioprotection Induced by Activation of GPER in Ovariectomized Rats With Pulmonary Hypertension.
  Allan K Alencar, Guilherme C Montes, Daniele G. Costa, Luiza V.P. Mendes, Ananssa M Silva
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2018-08-10

Journal Articles

• Adenosine A 2A  receptor agonist prevents cardiac remodeling and dysfunction in spontaneously hypertensive male rats after myocardial infarction  
  da Silva JS, Gabriel-Costa D, Sudo RT, Wang H, Groban L, Ferraz EB, Nascimento JH, Fraga CA, Barreiro EJ, Zapata-Sudo G, Drug Des Devel Ther, 1/6/2017
• Cardiomyocyte-specific deletion of the G protein-coupled estrogen receptor (GPER) leads to left ventricular dysfunction and adverse remodeling: A sex-specific gene pro...  
  Wang H, Sun X, Chou J, Lin M, Ferrario CM, Zapata-Sudo G, Groban L, Biochim Biophys Acta, 1/1/2017
• Effect of age, estrogen status, and late-life GPER activation on cardiac structure and function in the Fischer344xBrown Norway female rat  
  Alencar AK, da Silva JS, Lin M, Silva AM, Sun X, Ferrario CM, Cheng C, Sudo RT, Zapata-Sudo G, Wang H, Groban L, J Gerontol A Biol Sci Med Sci, 1/1/2017
• Mast cell inhibition attenuates cardiac remodeling and diastolic dysfunction in middle-aged, ovariectomized Fischer344xBrown Norway rats  
  Wang H, da Silva J, Alencar A, Zapata-Sudo G, Lin MS, Sun X, Ahmad S, Ferrario CM, Groban L, J Cardiovasc Pharmacol, 1/12/2016
• Primacy of cardiac chymase over angiotensin converting enzyme as an angiotensin-(1-12) metabolizing enzyme  
  Ahmad S, Varagic J, VonCannon JL, Groban L, Collawn JF, Dell'Italia LJ, Ferrario CM, Biochem Biophys Res Commun, 1/1/2016
• Activation of GPR30 improves exercise capacity and skeletal muscle strength in senescent female Fischer344 x Brown Norway rats  
  Wang H, Alencar A, Lin M, Sun X, Sudo RT, Zapata-Sudo G, Lowe DA, Groban L, Biochem Biophys Res Commun, 1/1/2016
• Intracrine angiotensin II functions originate from non-canonical pathways in the human heart  
  Ferrario CM, Ahmad S, Varagic J, Cheng CP, Groban L, Wang H, Collawn JF, Dell’Italia LJ, Am J Physiol Heart Circ Physiol, 1/1/2016
• Cardiac angiotensin-(1-12) expression and systemic hypertension in rats expressing the human angiotensinogen gene  
  Ferrario CM, VonCannon JL, Jiao Y, Ahmad S, Bader M, Dell’Italia LJ, Groban L, Varagic J, Am J Physiol Heart Circ Physiol, 1/1/2016
• GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number  
  Zhao Z, Wang H, Lin M, Groban L, Biochem Biophys Res Commun, 1/1/2015
• Activation of GPR30 inhibits cardiac fibroblast proliferation  
  Wang H, Zhao Z, Lin M, Groban L, Mol Cell Biochem, 1/1/2015
• Augmentation of autophagy by atorvastatin via Akt/mTOR pathway in spontaneously hypertensive rats  
  Wang W, Wang H, Geng QX, Wang HT, Miao W, Chang B, Zhao D, Song GM, Leanne G, Zhao Z, Hypertens Res, 1/1/2015
• Angiotensin-(1-12): a chymase-mediated cellular angiotensin II substrate  
  Ahmad S, Varagic J, Groban L, Dell’italia LJ, Nagata S, Kon ND, Ferrario CM, Curr Hypertens Rep, 1/1/2014
• Role of estrogen in diastolic dysfunction  
  Zhao Z, Wang H, Jessup JA, Lindsey SH, Chappell MC, Groban L, Am J Physiol Heart Circ Physiol, 1/1/2014
• Estrogen Replacement Downregulates Cardiac Angiotensin II in an ACE-independent Manner in Oophorectomized mRen2Lewis Rats  
  Wang H, Jessup JA, Zhao Z, da Silva J, Lin M, McNamara L, Ahmad S, Ferrario CM, Groban L, Plos ONE, 1/25/2013
• Estrogen replacement, independent of timing, improves cardiac structure and function in oophorectomized mRen2Lewis rats  
  Jessup JA, Wang H, MacNamara L, Presley TD, Kim-Shapiro DB, Zhang L, Chen AF, Groban L, Menopause, 1/1/2013
• Hemodynamic and hormonal changes to dual renin angiotensin system inhibition in experimental hypertension  
  Moniwa N, Varagic J, Ahmad S, VonCannon JL, Simington SW, Wang H, Groban L, Brosnihan KB, Nagata S, Kato J, Kitamura K, Gomez RA, Lopez ML, Ferrario CM, Hypertension, 1/1/2013
• Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats  
  Groban L, Wang H, Machado F, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI, Cardiovasc Endocrinology, 1/1/2012
• Activation of GPR30 attenuates diastolic dysfunction and left ventricle remodeling in oophorectomized mRen2Lewis rats  
  Wang H, Jessup JA, Lin MS, Chagas C, Lindsey S, Groban L, Cardiovasc Res, 1/1/2012
• Differential effect of late-life initiation of low-dose Enalapril and Losartan on diastolic function in Senescent Fischer 344 x Brown Norway Male Rats  
  Groban L, Lindsey S, Wang H, Lin M, Kassik K, Machado F, Carter C, Age (Dordr), 1/1/2012
• Angiotensin converting enzyme-2 deficiency is associated with impaired weight gain and fetal growth restriction  
  Bharadwaj MS, Strawn WB, Groban L, Yamaleyeva LM, Chappell MC, Horta C, Atkins K, Firmes L, Gurley SB, Brosnihan KB, Hypertension, 1/1/2011
• Dietary fish oil modestly attenuates the effect of age on diastolic function but has not effect on memory or brain inflammation in aged rats  
  Sergeant S, McQuail JA, Riddle DR, Chilton FH, Ortmeier SB, Jessup JA, Groban L, Nicolle MM, J Gerontol A Biol Sci Med Sci, 1/1/2011
• Continuing Medical Education Program in Echocardiography  
  Pohoey Fan, Leanne Groban, David M. Sanders, Timothy T. Houle, Benjamin L. Antonio, Edi C. Ntuen, David A. Zvara, Neal D. Kon, Edward H. Kincaid, Echocardiography, 1/1/2010
• Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by GPER activation in female mRen2Lewis rats  
  Jessup J, Lindsey SH, Wang H, Chappell MC, Groban L, PLoS One, 1/1/2010
• Diastolic function A barometer for cardiovascular risk?  
  Groban L, Kitzman DW, Anesthesiology, 1/1/2010
• Doppler E/e estimations of left ventricular filling pressure predict length of stay after cardiac surgery  
  Groban L, Sanders D, Houle T, Antonio B, Ntuen E, Zvara D, Kon N, Kincaid E, Echocardiography, 1/1/2010
• Join now to see all

Books/Book Chapters

• Sex Differences in Physiology 
  Chapter: Sex and gender differences in cardiovascular disease 
  Page 61 - 87Groban L, Lindsey S, Wang H, Alencar AKEditors: Neigh G, Mitzelfelt M.Academic Press (Elsevier), London2016
• Kaplan’s Cardiac Anesthesia: The Echo Era 
  Chapter: Cardiovascular Pharmacology 
  Royster RL, Groban L, Grosshans D, Jones-Haywood M, Slaughter TFEditors: Kaplan JA, Reich DL, Lake CL, Konstadt SN.Elsevier Saunders, PhiladelphiaEdition 6th,2011
• Protocolos en Cuidados Criticos 
  Chapter: Pulmonary artery cannulation 
  Whelan DM, Groban LEditors: Villar SR.Editorial Marban Libros, Madrid2011
• Protocolos en Cuidados Criticos 
  Chapter: Central venous cannulation 
  Whelan D, Groban LEditors: Villar SR.Editorial Marban Libros, Madrid2011
• Protocolos en Cuidados Criticos 
  Chapter: Arterial cannulation 
  Whelan DM, Groban LEditors: Villar SR.Editorial Marban Libros, Madrid2011
• Heart Failure Clinics, Diastolic Dysfunction and Heart Failure 
  Chapter: Exercise Intolerance 
  Page 99 - 116Kitzman DW, Groban LEditors: Vannan M, Pitt B.W.B. Saunders, Philadelphia2008
• Essentials of Cardiac Anesthesia 
  Chapter: Cardiovascular Pharmacology 
  Page 118 - 163Royster RL, Butterworth J, Groban L, Slaughter TF, Zvara DAEditors: Kaplan JA, Reich DL, Lake CL, Konstadt SN.Elsevier Saunders, Philadelphia2008
• Chronic Heart Failure 
  Chapter: Management of chronic heart failure 
  Butterworth J, Groban LEditors: Butterworth J.Wolters Kluwer/Lippincott Williams and Wilkins, Philadelphia2007
• Geriatric Anesthesiology 
  Chapter: Vascular procedures 
  Page 398 - 415Groban L, Dolinski SYEditors: Silverstein JH, Rooke GA, Reves JG, McLeskey CH.Springer, New YorkEdition 2nd,2007
• TEE Pocket Manual with PDA Access 
  Groban L, Butterworth JSaunders (Elsevier), Philadelphia2007
• Chronic Heart Failure 
  Chapter: Systolic vs. Diastolic Heart Failure 
  Groban LEditors: Butterworth J.Wolters Kluwer/Lippincott Williams and Wilkins, Philadelphia2007
• Conquer the PTEeXAM 
  Burch TM, Groban L, Zvara DASaunders (Elsevier), Philadelphia2007
• Complications in Regional Anesthesia and Pain Management 
  Chapter: Local anesthetic systemic toxicity 
  Groban L, Butterworth JEditors: Neal JM, Rathmell JP.Elsevier, Philadelphia2006
• Kaplan’s Cardiac Anesthesia 
  Chapter: Cardiovascular Physiology 
  Page 213 - 280Royster RL, Butterworth J, Groban L, Slaughter TF, Zvara DAEditors: Kaplan JA, Reich DL, Lake CL, Konstadt SN.Elsevier Saunders, PhiladelphiaEdition 5th,2006
• Fundamental Principles and Practice of Anaesthesia 
  Chapter: Pulmonary artery catheter introduction and interpretation 
  Page 1013 - 1017Groban L, Butterworth JEditors: Hutton P, Cooper GM, James III FM, Butterworth J.Martin Dunitz Ltd., London2002
• Fundamental Principles and Practice of Anaesthesia 
  Chapter: Establishing central venous access 
  Page 1009 - 1012Groban L, Butterworth JEditors: Hutton P, Cooper GM, James III FM, Butterworth J.Martin Dunitz Ltd., London2002
• Fundamental Principles and Practice of Anaesthesia 
  Chapter: Performing an arterial cannulation 
  Page 1003 - 1007Groban L, Butterworth JEditors: Hutton P, Cooper GM, James III FM, Butterworth J.Martin Dunitz Ltd., London2002
• Critical Care Medicine: Perioperative Management 
  Chapter: Procedures in the ICU 
  Dolinski S, Groban L, Butterworth JEditors: Murray, Coursin, Pearl, Prough.Lippincott Williams and Wilkins, Philadelphia2000
• Join now to see all

Abstracts/Posters

• Do sex differences in preoperative mobility, nutrition, and frailty status predict length of stay among older noncardiac surgical patients?
  Kim S, Edwards A, Roach CL, Rustowicz L, Marsh AP, Rejeski WJ, Kritchevsky S, Groban L, J Am Geriatr Soc, 1/1/2013
• Correlation of the Brain Medullary Metabolites N-acetyl Aspartic Acid and N-acetyl Aspartyl Glutamate With the Age Related Decline in Sensitivity for Baroreflex Contro...
  Diz D, Garcia-Espinosa MA, Shaltout HA, Olson J, Bourland JD, Groban L, Hypertension, 1/1/2011
• Early estrogen replacement prevents lusitropic impairment following ovariectomy in middle-aged cynomolgus monkeys
  Groban L, Jessup J, Register T, J Am Coll Cardiol, 1/1/2010
• Dietary Fish Oil Supplementation late in life attenuates diastolic dysfunction in Aged Brown Norway X Fisher 344 Rats
  Chagas C, Ortmeier S, Lin M, Wang D, Sergeant S, Chilton FH, Nicolle MM, Gerdes AM, Groban L, J Nutr Health Aging, 1/1/2010
• Surgery residents desire more training in geriatrics
  Petersen RP, Heflin MT, Groban L, Lagoo-Deenadayalan SA, J Am Geriatr Soc, 1/1/2009
• GPR30 receptor activation improves cardiac function in intact female mRen2.Lewis rats
  Jessup J, Lindsey S, Chappell M, Groban L, J Card Fail, 1/1/2009
• GH repletion increases intracardiac Ang-1- 7/ACE2 and restores diastolic function in aged male BNF344 rats
  Groban L, Lin MR, Jessup JA, Chappell MC, Brunso-Bechtold JK, J Card Fail, 1/1/2009
• Effects of human amniotic fluid derived stem cells on cardiac function after myocardial infarction
  Delo DM, Wang Z, Shaffer R, Guan X, Neshat S, Smith T, Callahan M, Groban L, Atala A, Soker S, Tissue Eng Part A, 1/15/2008
• Combination Renin Angiotensin System Improves Ventricular Lusitropy Without Affecting Cardiac Fibrosis or Cardiac RAS in the Hypertensive mRen2.Lewis Rat
  Jessup JA, Westwood BM, Chappell MC, Groban L, Circulation Research, 1/1/2008
• Effects of Aging and Renin-Angiotensin System (RAS) Blockade on the Intra-renal RAS in Older Fischer 344 X Brown Norway Rats
  Kasper SO, Gilliam-Davis S, Groban L, Carter CS, Sonntag WE, Chappell MC, Diz DI, FASEB J, 1/1/2008
• Diastolic dysfunction predicts adverse outcome after cardiac surgery
  Sanders D, Houle T, Kon N, Zvara D, Groban L, Anesthesiology, 1/1/2008
• Inhibition of Angiotensin-Coverting Enzyme 2 Aggravates Cardiac Hypertrophy in Ren-2 Hypertensive Rats
  Trask AJ, Groban L, Varagic J, Ferrario CM, Hypertension, 1/1/2008
• Transgenic Rats with Low Brain Renin-angiotensin System Activity Due to Glial Deficiency are Protected Against Heart Failure Late in Life
  Groban L, Ferrario CM, Ganten D, Diz DI, 11th Annual Scientific Meeting Heart Failure Society of America, Washington, DC, 1/16/2007
• Improvements in Diastolic Function by Exercise Training and Growth Hormone (GH) Replacement in the Aged Rodent are Regulated by Different Mechanisms
  Groban L, Jobe H, Lin M, Bennett C, Sonntag B, American Geriatrics Society 2007 Annual Scientific Meeting, Seattle, Washington, 1/2/2007
• Decreased expression of cardiac ACE2 is associated with salt-induced cardiac remodeling and dysfunction
  Varagic J, Brosnihan KB, Groban L, Gallagher PE, Ferrario CM, Hypertension, 1/1/2007
• Increased intra-renal IGF-1 is associated with renal injury in older estrogen-depleted mRen2.Lewis rats
  Yamaleyeva L, Gallagher P, Groban L, Chappell MC, FASEB J, 1/1/2007
• Amniotic fluid derived stem cells for cardiac therapeutics
  Delo D, Neshat S, Christ G, Groban L, Olson J, Zhu JM, Atala A, Shoker S, FASEB J, 1/1/2007
• Transgenic Rats with low brain renin-angiotensin system activity due to glial deficiency are protected against heart failure late in life
  Groban L, Ferrario CM, Ganten D, Diz DI, J Card Fail, 1/1/2007
• Your worst nightmare: An urgent pericardial window in a morbidly obese patient with severe pulmonary hypertension and a large pericardial effusion
  Groban L, 58th Annual Meeting of the American Society of Anesthesiologists, Inc., 1/1/2007
• Local anesthetic-induced cardiac toxicity: a survey of contemporary practice strategies among academic anesthesiology departments
  Corcoran W, Beck J, Gerancher J, Butterworth J, Groban L, International Anesthesia Research Society, 80th Clinical and Scientific Congress, San Francisco, California, 1/24/2006
• Impact of age and growth hormone on anesthetic-induced alterations in cardiac performance
  Beck C, Bennett C, Sonntag W, Groban L, Anesth Analg, 1/1/2006
• Local anesthetic-induced cardiac toxicity: a survey of contemporary practice strategies among academic anesthesiology departments
  Corcoran W, Beck C, Gerancher J, Butterworth J, Groban L, Anesth Analg, 1/1/2006
• Long-term growth hormone replacement or angiotensin receptor blockade prevents both cognitive impairment and cardiac diastolic dysfunction in aged rats
  Nicolle MM, Bennett CDL, Lin MR, Sonntag WE, Groban L, Neuroscience, 1/1/2006
• Ovariectomy is protective against salt-induced renal injury in the older mRen2.Lewis strain
  Yamaleyeva LM, Westwood BM, Groban L,Chappell MC, Hypertension, 1/1/2006
• Cardiac surgical intensive care unit readmissions: Does preoperative diastolic dysfunction have a role?
  Antonio B, Houle T, Kincaid T, Groban L, Crit Care Med, 1/1/2006
• Join now to see all

Lectures

• Introduction to Geriatric Anesthesia 
  1/1/2018
• Systolic Hypertension and Vascular Aging 
  1/1/2018
• Diastolic Function and Cardiac Aging 
  1/1/2018
• Aortic Valve Exam 
  1/1/2018
• Doppler Exam and Diastolic Function 
  1/1/2018
• Diastolic Dysfunction 
  1/1/2018
• “Local Anesthesia and Anesthetics 
  1/1/2018
• General Anesthesia and Anesthetics 
  1/1/2018
• Monitoring 
  1/1/2018
• What’s at the heart of sex-specific diastolic dysfunction? 
  Tulane School of Medicine, New Orleans, LA - 1/1/2017
• Using TEE to diagnose diastolic dysfunction and heart failure 
  San Diego, CA - 1/27/2016
• Mast cell attenuates cardiac remodeling and diastolic dysfunction in ovariectomized BNF344 female rats 
  San Diego, California - 1/24/2015
• Chronic activation of GPR30 attenuates diastolic dysfunction in oophorectomized senescent rats 
  San Diego, California - 1/24/2015
• Preoperative Assessment and Risk Stratification of the Older Surgical Patient: Are we missing something? 
  Montreal, Canada, 2014; University of Alabama School of Medicine, Birmingham, AL, 2014; Virginia Com - 1/5/2015
• Role of Estrogen in Diastolic Dysfunction 
  Morgantown, WV, 2014; University of Alabama School of Medicine, Birmingham, AL, 2014 - 1/15/2014
• Highlights of the Guidelines for Diagnosis and Management of Adult Chronic Heart Failure 
  New Orleans, LA - 1/12/2014
• Risk Stratification and Evaluation of the Older Surgical Patient: Are We Missing Something? 
  Montreal, Canada - 1/1/2014
• Is mobility disability related to length of stay in elderly patients undergoing elective noncardiac surgery? 
  Miami, Florida - 1/1/2013
• Translational Research in Cardiac Aging and Diastolic Dysfunction 
  San Antonio, Texas, 2011; Salt Lake City, Utah, 2011; Omaha, Nebraska, 2012 - 1/1/2012
• Diastolic Dysfunction: The Great Masquerader 
  Washington, DC - 1/14/2011
• Does Diastology Really Matter? Operative Implications of Diastolic Dysfunction 
  Savannah, GA - 1/1/2011
• Perioperative Implications of Diastolic Dysfunction 
  1/1/2011
• Demographics of Cardiac Surgery for the Older patient 
  1/27/2010
• Basics of Echocardiograph 
  1/27/2010
• Cardiovascular Aging – A clinician-scientist’s perspective 
  Department of Anesthesiology, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma - 1/25/2010
• Join now to see all

Other

• Perioperative Care Module in Essentials of Cardiovascular Care in Older Adults (ECCOA) 
  Groban L, Cherr G, Dolinski S, Rich M
  http://www.cardiosource.com/accis_index.asp
  1/11/2009
• Understanding anesthesia and the impact of aging on the cardiovascular system 
  Groban L, A Geriatric Anesthesiology Curriculum
  http://www.asahq.org/clinical/GeriatricAnesthesiologyCurriculum_123007.pdf
  1/1/2008
• Hemodynamic, Renal and Hormonal Responses to Incremental Atrial Natriuretic Factor (ANF) Infusion in Humans 
  Groban L, MS Thesis
  University of Wisconsin at Milwaukee, Milwaukee, Wisconsin
• Perioperative care of older patients: viewpoints from anesthesia and surgical residents 
  Laxton M, Porter J, Carter J, Groban L
  http://www.aghe.org/clientimages/40634/aghe_2013program.pdf
• Join now to see all