Lawrence Richard Kleinberg MD

Radiation Oncology•Baltimore, MD

Central Nervous System Cancer

Associate Professor of Radiation Oncology and Molecular Radiation Sciences, Associate Professor of Neurological Surgery, Associate Professor of Oncology, Johns Hopkins University School of Medicine

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401 North Broadway StreetWeinberg BLDG, Floor-L1 (Lobby Level)Baltimore, MD 21287
Phone+1 410-955-6980
Fax+1 410-502-1419

Education & Training

Memorial Sloan Kettering Cancer CenterResidency, Radiation Oncology, 1990 - 1993
Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalInternship, Internal Medicine, 1989 - 1990
Yale School of MedicineClass of 1989

Certifications & Licensure

DC State Medical License 2019 - 2027
MD State Medical License 1993 - 2026
VA State Medical License 2024 - 2026
NC State Medical License 2021 - 2022
NY State Medical License 1990 - 1994
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2008-2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
America's Top Doctors for Cancer Castle Connolly, 2007-2013
Top Doctors:Baltimore Area Castle Connolly, 2012
Top Doctors:Washington-Baltimore Castle Connolly, 2012
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Clinical Trials

Low Dose Radiation Therapy for Glioblastoma Multiforme Start of enrollment: 2012 Sep 01
Completed
Phase 2
Stereotactic Body Radiation With Nelfinavir for Oligometastases Start of enrollment: 2014 Jan 08
Completed
Phase 2
Radiotherapy for Solid Tumor Spine Metastases Start of enrollment: 2013 May 20
Completed
Phase 2
Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung Cancer Start of enrollment: 2013 Mar 11
Completed
Not Applicable
Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme Start of enrollment: 2014 Jul 08
Recruiting
Phase 2
Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma Start of enrollment: 2017 Sep 20
Active, not recruiting
Phase 2
5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme Start of enrollment: 2017 Oct 18
Completed
Early Phase 1
Pilot Study Using Amide Proton Transfer Magnetic Resonance Imaging Distinguishing Glioma Start of enrollment: 2014 Aug 01
Terminated
Not Applicable
Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma Start of enrollment: 2022 Aug 31
RECRUITING
PHASE1
Roles: Principal Investigator, Contact
Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant with RT & TMZ for the Treatment of Newly Diagnosed GBM Start of enrollment: 2020 Dec 08
ACTIVE_NOT_RECRUITING
NA
Roles: Contact
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Publications & Presentations

PubMed

Comparison of Proton Versus Photon SBRT for Treatment of Spinal Metastases Using Variable RBE Models.
Sherif G Shaaban, Michael LeCompte, Hao Chen, Daniel Lubelski, Ali Bydon
International Journal of Particle Therapy. 2025-06-01
Prevalence, treatment patterns, and survival of patients with brain metastases from small cell lung cancer: A retrospective study using the TriNetX Oncology Database.
Megan Parker, Anita Kalluri, Kelly Jiang, Joshua Materi, Tej D Azad
Neuro-Oncology Practice. 2025-04-01
Effect of long and short half-life PDE5 inhibitors on HbA1c levels: a systematic review and meta-analysis.
Joseph Kim, Rui Zhao, Lawrence Richard Kleinberg, Kitai Kim
Eclinicalmedicine. 2025-02-01

Professional Memberships

American Society of Clinical Oncology - ASCO
Member

External Links

Johns Hopkins Physicianshttp://www.hopkinsmedicine.org/lawrence-kleinberg