Lawrence Anthony Dunn MD (He/Him)

Journal Articles

• Impact of clozapine on negative symptoms and on the de?cit syndrome in refractory schizophrenia.  
  Rosenheck, R., Dunn, L., Pezke, M., Cramer, J, Weichun, X, Thomas, J., Charney, D., Henderson, W., Allen, E., Chang, S., Choe, Y., Crayton, J. Douyon, R., Erdos, J...., American Journal of Psychiatry, Vol. 156:1
• Clinical and psychopharmacologic Factors in?uencing family burden in refractory schizophrenia.  
  Rosenheck R., Cramer J., Jurgis, G., Perlick, D.,, Linda K., Xu W., Thomas J., Allan, E., Erdos, J., Frisman, Henderson W., Tekell J. Peters J. Fontana A., Allen, E.,..., Journal of Clinical Psychiatry Vol. 61:9
• Quality of life in schizophrenia: a comparison of instruments.  
  Cramer J. Rosenheck R. Xu W. Thomas J. Henderson W., Jurgis, G., Perlick, D., Linda K., Allan, E., Erdos, J., Frisman, Tekell J. Peters J. Fontana A., Allen, E., Chan..., Schizophrenia Bulletin 26:3
• Detecting improvement in quality of life and symptomatology in schizophrenia.  
  Cramer J., Rosenheck R., Xu W, Henderson W., Thomas, J., Jurgis, G., Perlick, D., Linda K., Allan, E., Erdos, J., Frisman, Tekell J. Peters J. Fontana A., Allen, E., ..., Schizophrenia Bulletin 27:2
• A Comparison of Risperidone and Haloperidol for the Prevention of Relapse in Patients with Schizophrenia.  
  Csernansky, J, Mahmoud, R., Brenner, R., Adan, F., Brown, D., Austin, J., Chou, C., Cohn, M., DePriest B., Cole, L. Dunn, L., Goodman, W., Byerly, M., Green, A., Kleg..., New England Journal of Medicine Vol 346:1
• Effectiveness and Cost of Olanzapine and Haloperidol in the Treatment of Schizophrenia.  
  Rosenheck, R., Perlick, P., Bingham, S., Liu-Mares, W., Collins, J., Warren, S., Leslie, D., Allan, E., Campbell, E., Caroff, S., Corwin, J., Davis, L., Douyon, R., ..., Journal of the American Medical Association Vol 290:20
• Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.  
  CE, Keefe RS, Buchanan RW, Hamer RM, Kilts JD, Bradford DW, Strauss JL, Naylor JC, Payne VM, Lieberman JA, Savitz AJ, Leimone LA, Dunn L, Porcu P, Morrow AL, Shampine LJ, Neuropsychopharmacology Vol 34:8
• Medication continuation and compliance: a comparison of patients treated with clozapine and haloperidol.  
  Rosenheck R. Chang S. Choe Y. Cramer J. Xu W. Thomas J. Henderson W., Jurgis, G., Perlick, D., Linda K., Xu W., Thomas J., Allan, E., Erdos, J., Frisman, Tekell J. Pe..., Journal of Clinical Psychiatry. 61:5
• Cost-effectiveness of clozapine in patients with high and low levels of hospital use.  
  Rosenheck R., Cramer J., Allan, E., Erdos, J., Frisman, Linda K., Xu W., Thomas J., Henderson W., Tekell J. Peters J. Fontana A., Allen, E., Chang, S., Choe, Y., Cray..., Archives of General Psychiatry. Vol. 56:6
• Catecholamine Secretion from Digitonin-Treated Adrenal Medullary Chromaffin Cells.  
  Dunn, Lawrence A., and Ronald W. Holz, Journal of Biological Chemistry Vol. 258, No. 8
• Predictors of differential response to clozapine and haloperidol.  
  Rosenheck, R., Lawson, W., Crayton, J., Cramer, J., Weichun, X., Thomas, J., Stolar, M., Charney, D., Grabowski, J., Douyon, R.,Henderson, W., Evans, D., Herz, L., Du..., Biological Psychiatry Vol. 44
• Multiple outcome assessment in a study of the cost-effectiveness of clozapine in the treatment of refractory schizophrenia.  
  Rosenheck, R., Cramer, J, Weichun, X., Grabowski, J., Douyon, R., Thomas, J., Henderson, W., Charney, D., Allen, E., Chang, S., Choe, Y., Crayton, J. Dunn, L., Erdos,..., HSR: Health Services Research Vol. 33:5, Part 1
• Does participation in psychosocial treatment augment the bene?t of clozapine?  
  Rosenheck R. Tekell J. Peters J. Cramer J. Fontana A. Xu W. Thomas J. Henderson W. , Allen, E., Chang, S., Choe, Y., Crayton, J. Douyon, R., Dunn, L., Erdos, J., Evan..., Archives of General Psychiatry.Vol. 55:7
• Clozapine treatment for refractory schizophrenia: A longitudinal study of effectiveness and cost.  
  Rosenheck, R., Charney, D., Cramer, J, Xu, W., Thomas, J., Henderson, W., Allen, E., Chang, S., Choe, Y., Crayton, J. Douyon, R., Dunn, L., Erdos, J., Evans, D., Grab..., New England Journal of Medicine, Vol. 337
• Severe hyperglycemia associated with high doses of clozapine.  
  Kamran, A., Doraiswamy P.M., Jane, J.L., Hammett, E.B., Dunn, L, The American Journal of Psychiatry
• Response to the letter to the editors:The latent inhibition model of schizophrenic attention disorder and antipsychotic drug action: comment on Dunn,Atwater and Kilts.  
  Dunn, Lawrence A, Psychopharmacology Vol. 116
• Effects of Antipsychotic Drugs on Latent Inhibition: Sensitivity and Speci?city of an Animal Behavioral Model of Clinical Drug Action.  
  Dunn, Lawrence A., Gail E. Atwater, and Clinton D. Kilts, Psychopharmacology Vol. 112
• Haloperidol Enhancement of Latent Inhibition: Relation to Therapeutic Action?  
  Christison, George W., Gail E. Atwater, Lawrence A. Dunn, and Clinton D. Kilts, Biological Psychiatry,Vol.23
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Books/Book Chapters

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  Chapter: Animal Behavioral Models for Drug Development in Psychopharmacology 
  Page 259 - 280Dunn, Lawrence A., Clinton D. Kilts, and CharlesEditors: W.H. Moos, and J.S. Clark.VCH and Ellis Horwood Publishers Inc, Chichester

Abstracts/Posters

• Calmodulin Regulation of a Presynaptic Cytosol Protein Kinase System.
  Dunn, Lawrence A., James P. O'Callaghan, and Walter Lovenberg, Clinical Research, 29, No. 4
• Reaction Time and Pupil Response Measures Show Reduced Latent Inhibition in Chronic Schizophrenia.
  Dunn, Lawrence A. and Richard J. Scibilia, Society for Neuroscience Abstracts, Vol. 22, Part 1
• Intra-accumbens Clozapine and Haloperidol Enhance Latent Inhibition in Rats.
  Dunn, Lawrence A. and Richard J. Scibilia, Society for Neuroscience Abstracts, Vol. 21, Part 1
• Clozapine and Olanzapine Enhance Latent Inhibition at Low but not High Doses in Rats.
  Dunn, Lawrence A. and Richard J. Scibilia, Society for Neuroscience Abstracts, Vol. 20, Part 1
• Clozapine Modulation of Latent Inhibition in Rats.
  Dunn, Lawrence A. and Richard J. Scibilia, Society for Neuroscience Abstracts, Vol. 19, Part 1
• A Reaction Time Based Continuous Performance Task for Measurement of Latent Inhibition in Human Subjects.
  Dunn, Lawrence A, Society for Neuroscience Abstracts,Vol.18, Part 2
• Comparison of the Effects on Latent Inhibition of Dopamine Agonists and Atypical Antipsychotics in Rats.
  Dunn, Lawrence A., Richard J. Scibilia, Jean A. Franks, and, Clinton D. Kilts, Society for Neuroscience Abstracts, Vol. 17, Part 1
• Selective Breeding for Distinct Stimulus Filtering / Selective Attention Phenotypes.
  Kilts, Clinton D., Richard J. Scibilia, and Lawrence A. Dunn, Society for Neuroscience Abstracts, Vol. 16, Part 1
• The Effect of Clozapine on Stimulus Filtering / Selective Attention in Rats.
  Dunn, Lawrence A., Richard J. Scibilia, Gregory Schutrum, and, Clinton D. Kilts, Society for Neuroscience Abstracts, Vol. 16, Part 2
• Latent Inhibition as an Animal Model of Antipsychotic Drug Action.
  Dunn, Lawrence A., Gail E. Atwater, George W. Christison, and Clinton D. Kilts, Society for Neuroscience Abstracts, Vol. 15, Part 1
• Selective Enhancement of Latent Inhibition by Antipsychotic Drugs in the Rat: A Possible Model for Clinical Action.
  Dunn, Lawrence A., Gail E. Atwater, George W. Christison, and Clinton D. Kilts, Society for Neuroscience Abstracts, Vol. 14, Part 2
• Calmodulin Mediated Phosphorylation of Synaptosomal Cytosolic Proteins.
  O'Callaghan, James P., Lawrence A. Dunn, and Walter Lovenberg, Annals of the New York Academy of Sciences, Vol. 356. (1980)
• Congenital Cardiac Abnormalities Produced in Chicken Embryos Through Mechanical Interference With Cardiogenesis.
  Dunn, Lawrence A, Abstracts 26th International Science and Engineering Fair, Washington DC
• Tardive Dyskinesia.
  Dunn, Lawrence A, Southern Medical Association, Birmingham, AL
• Clozapine Treatment of Schizophrenia.
  Dunn, Lawrence A, Southern Medical Association, Birmingham, AL
• Etiology and Pathophysiology of Schizophrenia.
  Dunn, Lawrence A, Southern Medical Association, Birmingham, AL
• Treatment of Schizophrenia.
  Dunn, Lawrence A, Southern Medical Association, Birmingham, AL
• Differential Diagnosis of Schizophrenia.
  Dunn, Lawrence A, Southern Medical Association, Birmingham, AL
• Schizophrenia: Clinical Features.
  Dunn, Lawrence A, Southern Medical Association, Birmingham,AL
• Cell Fusion as a Research Tool.
  Dunn, Lawrence A., and Ronald W. Holz, University of Michigan Medical School
• Calcium -Regulated Phosphorylation in Synaptosomal Cytosol: Dependence on Calmodulin.
  O'Callaghan, James P., Lawrence A. Dunn, and Walter Lovenberg, Proceedings of the National Academy of Science USA,Vol.77,No.10
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