LaurenDanielStegmanMDPhD, DABR

PubMed

• 49 citations
  Induction of Cytotoxic Oxidative Stress by d-Alanine in Brain Tumor Cells Expressing Rhodotorula gracilis d-Amino Acid Oxidase: A Cancer Gene Therapy Strategy
  Lauren D. Stegman, Hong Zheng, Eric R. Neal, Oded Ben-Yoseph, Loredano Pollegioni
  Human Gene Therapy. 1998-01-20
• 159 citations
  Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting--the MSKCC experience
  Bradford S. Hoppe, Lauren D. Stegman, Michael J. Zelefsky, Kenneth E. Rosenzweig, Suzanne L. Wolden
  International Journal of Radiation Oncology, Biology, Physics. 2007-03-01
• 348 citations
  Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging.
  Alnawaz Rehemtulla, Lauren D. Stegman, Shaun Cardozo, Sheila Gupta, Daniel E. Hall
  Neoplasia. 2000-01-01

Journal Articles

• P MRS evaluation of ganciclovir toxicity in C6 gliomas stably expressing the herpes simplex thymidine kinase gene.  
  Stegman LD, Ben-Yoseph O, Freyer JP, and Ross BD, NMR in Biomedicine
• Phylogenetic footprinting of hypersensitive site 3 of the ?-globin locus control region.  
  Shelton DA, Stegman L, Hardison R, Miller W, Bock JH, Slightom JL, Goodman M, and Gumucio DL, Blood
• Induction of cytotoxic oxidative stress by D-alanine in brain tumor cells expressing Rhodotorula gracilis D -amino acid oxidase: a cancer gene therapy strategy.  
  Stegman LD, Zheng H, Neal ER, Ben-Yoseph O, Pollegioni L, Pilone MS, and Ross BD, Human Gene Therapy
• Contributions of cell kill and post-treatment tumor growth rates to the repopulation of intracerebral 9L tumors after chemotherapy: an MRI study.  
  Ross BD, Zhao YJ, Neal ER, Stegman LD, Ercolani M, Ben-Yoseph O, and Chenevert TL, Proceedings of the National Academy of Sciences of the USA
• Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with in vivo magnetic resonance spectroscopy.  
  Stegman LD, Rehemtulla A, Beattie B, Kievit E, Lawrence TS, Blasberg RG, Tjuvajev JG, and Ross BD, Proceedings of the National Academy of Sciences of the USA
• Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging.  
  Rehemtulla A, Stegman LD, Cardozo SJ, Gupta S, Hall DE, Contag CH, and Ross BD, Neoplasia
• Yeast cytosine deaminase improves radiosensitization and bystander effect by 5-fluorocytosine of human colorectal cancer xenografts.  
  Kievit E, Nyati MK, Ng E, Stegman LD, Parsels J, Ross BD, Rehemtulla A, and Lawrence TS, Cancer Research
• Diffusion MRI detects early events in the response of a glioma model to the yeast cytosine deaminase gene therapy strategy.  
  Stegman LD, Rehemtulla A, Hamstra DA, Rice DJ, Jonas SJ, Stout KL, Chenevert TL, and Ross BD, Gene Therapy
• Experimental gliosarcoma induces chemokine receptor expression in rat brain.  
  Galasso JM, Stegman LD, Blaivas M, Harrison JK, Ross BD, and Silverstein FS, Experimental Neurology
• Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.  
  Chenevert TL, Stegman LD, Taylor JM, Robertson PL, Greenberg HS, Rehemtulla A, and Ross BD, ournal of the National Cancer Institute
• Molecular imaging of gene expression and efficacy following adenoviral-mediated brain tumor gene therapy.  
  Rehemtulla A, Hall DE, Stegman LD, Prasad U, Chen G, Bhojani MS, Chenevert TL, Ross BD, Molecular Imaging
• Evaluation of (E)-2’-deoxy-2’-(fluoromethylene)cytidine on the 9L rat brain tumor model using MRI.  
  Ross BD, Chenevert TL, Garwood M, Kim B, Stegman LD, Ben-Yoseph O, Zwolshen J, Rehemtulla A, and Sunkara PS, MR Biomed
• Post-operative radiotherapy in the treatment of nasal cavity and paranasal sinus cancer.  
  Hoppe BS, Stegman LD, Zelefsky MJ, Rosenzweig K, Wolden S, Narayana A, Patel SG, Shah J, Kraus DH, and Lee N, International Journal of Radiation Oncology ? Biology ? Physics
• Long-term clinical outcomes of whole breast irradiation delivered in the prone position.  
  Stegman LD, Beal KP, Hunt MA, Fornier MN, and McCormick B, International Journal of Radiation Oncology ? Biology ? Physics
• Unresectable Carcinoma of the Paranasal Sinuses: Outcomes and Toxicities.  
  Hoppe BS, Nelson CJ, Gomez DR, Stegman LD, Wu AJ, Wolden SL, Pfister DG, Zelefsky MJ, Shah JP, Kraus DH, Lee NY, International Journal of Radiation Oncology ? Biology ? Physics
• Noninvasive quantitation of chemotherapeutic cell kill in experimental intracranial brain tumors using MRI.  
  San Diego, CA, 88th Annual Meeting of the American Association for Cancer Research
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Abstracts/Posters

• Assessment of cancer treatment using magnetic resonance imaging and spectroscopy: Application to gene therapy and chemotherapy.
  Ross BD, Stegman LD, Chenevert TL, and Rehemtulla A, 4th International Symposium of Predictive Oncology and Therapy - Impact of Biotechnology on Cancer, Nice, France
• SBRT is non-­‐inferior to standard chemoradiation for locally advanced, non-­metastatic pancreas cancer: A meta-­analysis of published data.
  Jessica Varley, Thomas B. Daniels, MD, John J. Kresl, MD, PhD, FACRO, Chad L. Lee, PhD, and Lauren D. Stegman, MD, PhD, Radiosurgery Society International Meeting, San Diego, CA
• Trends in the publication of radiotherapy research and randomized controlled trials involving radiotherapy: A bibliometric analysis.
  Stegman LD, Alektiar KA, 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Philadelphia, PA
• Long-term clinical outcomes of prone breast radiotherapy.
  Stegman LD, Hunt MA, and McCormick B., 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Denver, CO.
• Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescent imaging.
  Rehemtulla A, Stegman LD, Cardozo SJ, Gupta S, Hall DE, Contag CH, and Ross BD, 92nd Annual Meeting of the American Association for Cancer Research, New Orleans, LA.
• Diffusion magnetic resonance imaging: A surrogate marker for therapeutic efficacy in brain tumors.
  Chenevert TL, Stegman LD, Taylor JMG, Greenberg HS, Robertson PL, Rehemtulla A, and Ross BD, 92nd Annual Meeting of the American Association for Cancer Research, New Orleans, LA
• Adenoviral yeast cytosine deaminase gene therapy of the intracerebral 9L tumor.
  Ross BD, Stegman LD, Rehemtulla A and Chenevert TL, 5th Annual Meeting of the Society of Neuro-Oncology, Chicago, IL
• Early prediction of therapeutic efficacy in experimental and human brain tumors using diffusion MRI.
  Ross BD, Stegman LD, Rehemtulla A and Chenevert TL, 5th Annual Meeting of the Society of Neuro-Oncology, Chicago, IL
• Diffusion MRI evaluation of treatment response to yeast cytosine deaminase gene therapy in an orthotopic rat glioma model.
  Stegman LD, Rehemtulla A, Chenevert TL and Ross BD, 1st Annual Meeting of the American Association of Cancer Research, San Francisco, CA.
• Noninvasive quantitation of cytosine deaminase gene expression in vivo using 19 F-magnetic resonance spectroscopy.
  Stegman LD, Rehemtulla A, Beattie B, Kievit E, Lawrence TL, Blasberg RG, Tjuvajev JG and Ross BD, 90th Annual Meeting of the American Association of Cancer Research, Philadelphia, PA
• The use of magnetic resonance imaging and spectroscopy for evaluating gene transfer, expression and therapeutic efficacy in experimental tumor models.
  oss BD, Stegman LD, Chenevert TL, Rehemtulla A, and Weissleder R, nternational Symposium on Gene Imaging and Radio-Gene Therapy, A Satellite Meeting of the 6th Inter, Kallithea, Halkidiki, Greece
• Phosphorus MRS assessment of ganciclovir toxicity in subcutaneous gliomas stably expressing the herpes simplex thymidine kinase gene.
  Stegman LD, Ben-Yoseph O, Breakefield XO, Freyer JP, and Ross BD, 4th Annual Meeting of the International Society for Magnetic Resonance in Medicine, New York, NY
• Transplanted 9L gliosarcomas induce expression of the monocyte chemoattractant protein-1 (MCP-1) receptor, CCR2, in rat brain.
  Galasso JM, Ross BD, Stegman LD, Harrison JK, and Silverstein FS, 8th Annual Meeting of the Society for Neuroscience, Los Angeles, CA.
• Assessment of transgene expression and metabolic response to a novel oxidative stress-inducing cancer gene therapy paradigm using 13C and 31P magnetic resonance spec...
  Stegman LD, Freyer JR, Neal ER, and Ross BD, ixth Annual Meeting of the International Society for Magnetic Resonance, Sydney, Australia
• Cancer gene therapy with R. gracilis D-amino acid oxidase produces cytotoxic oxidative stress.
  Stegman LD, Zheng H, Neal ER, Ben-Yoseph O, Pollegioni L, Pilone MS and Ross BD, nternational Institute of Anticancer Research “Gene Therapy in Cancer”, Athens, Greece.
• Magnetic resonance imaging of orthotopic brain tumor models: An alternative approach for assessing therapeutic efficacy.
  Ross BD, Neal ER, Zhao YJ, Stegman LD and Chenevert TL, International Institute of Anticancer Research “Gene Therapy in Cancer”, Athens, Greece.
• Noninvasive quantitation of chemotherapeutic cell kill and water diffusion changes in 9L brain tumors using MRI.
  Ross BD, Zhao YJ, Neal ER, Ercolani M, Stegman LD, Fritsma L, and Chenevert TL, 2nd Annual Meeting of the Society for Neuro-Oncology, Charlottesville, VA
• Radical gene therapy using D-amino acid oxidase.
  Stegman LD, Zheng H, Neal ER, Pollegioni L, Pilone MS and Ross BD, 2nd Annual Meeting of the Society for Neuro-Oncology, Charlottesville, VA
• Gene therapy of gliomas using D-amino acid oxidase.
  Stegman LD, Zheng H, Neal ER, Pollegioni L, Pilone MS and Ross BD, 12th International Conference on Brain Tumor Research and Therapy, Oxford, United Kingdom
• Quantitation of cell kill in intracranial 9L tumors by MRI.
  Ross BD, Zhao YJ, Neal ER, Ercolani M, Stegman LD, and Chenevert TL, 12th International Conference on Brain Tumor Research and Therapy, Oxford, United Kingdom
• A SKL-deleted mutant of R. gracilis D- amino acid oxidase.
  Ross BD, Zhao YJ, Ercolani M, Ben-Yoseph O, Stegman LD, and Chenevert TL, 2nd European Symposium of the Protein Society, Vancouver, British Columbia, Canada
• A novel suicide gene therapy strategy with the H2O2-generating enzyme D-amino acid oxidase.
  Stegman LD, Zheng H, Neal ER, Pollegioni L, Pilone MS, Ben-Yoseph O, and Ross BD, 88th Annual Meeting of the American Association for Cancer Research, San Diego, CA
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Lectures

• Stereotactic Radiosurgery and Stereotactic Body Radiotherapy 
  Cancer Registrars Association of Arizona Annual Meeting
• Radiation Therapy for Esophageal Cancer. 
  Wellness Community Esophageal Cancer Symposium
• Radiation Therapy for the Internist. 
  Banner Good Samaritan Medical Center Internal Medicine Grand Rounds
• An Introduction to Stereotactic Radiosurgery 
  Banner Desert Medical Center Radiosurgery Symposium
• Radiation Therapy for Prostate Cancer. 
  Banner Gateway Medical Center Grand Rounds
• SBRT is non-­‐inferior to standard chemoradiation for locally advanced, non-­metastatic pancreas cancer: A meta-­analysis of published data. 
  Invited Oral Presentation, The Radiosurgery Society International Meeting, San Diego, CA
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