LarryMillerMD

Summary

• I am a third tier trained therapeutic endoscopist and I am also trained, and board certified in nutrition. In addition, I am a trained bench lab and clinical research scientist, having completed a three-year research fellowship at the Digestive Disease Section of the NIDDK. I currently hold the position as Chief of Gastroenterology at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and Vice Chair for Research at Northwell Health. I have spent much of my research career as head of endoscopic research at both Thomas Jefferson University and at Temple University in Philadelphia. I am currently involved in the bioelectronics initiative at the Feinstein Research Center, and I have been involved in three SPARC grants. One to record the electrical activity of the stomach a second to access peripheral branches of the vagus nerve for purposes of stimulating those branches. A third to map the vagus nerve (REVA). Part of my research interests is the design and invention of devices. I have invented and patented several different devices. In the early 1990’s, I invented a method using simultaneous high-resolution ultrasound and manometry to study the anatomy and physiology of gastrointestinal sphincters. As part of my previous NIH sponsored research work, I studied the mechanics, physiology, and pathophysiology of the high-pressure zone of the distal esophagus. My first RO1 grant dealt specifically with normal sphincter anatomy and physiology of the distal esophageal anti-reflux barrier. My second NIH RO1 grant clinically investigated the pathophysiology of GERD and we discovered several new pathophysiologic mechanisms in GERD. My completed NIH SPARC grant used new endoscopic techniques to implant electrodes on the peripheral branches of the vagus nerve. I became interested in the selective stimulation of efferent and afferent nerve fascicles within the cervical vagus nerve.