Kuan-Hsiang GaryHuangMDPhD MSc

Allergy & Immunology • Philadelphia, PA

Asthma & Allergic Conditions, Pediatric Asthma & Allergic Conditions, Clinical & Laboratory Immunology

Director, Clinical Research Gastroenterology, Janssen R&D US

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Office
5501 Old York Rd Bldg 300
Philadelphia, PA 19141
Phone+1 215-456-6950

Fax+1 215-456-1766

Summary

Gary KH Huang, MD PhD MSc, is a director and study responsible physician at the Immunology Clinical Development of Janssen Research & Development (Pharmaceutical Companies of Johnson & Johnson).

A Rhodes Scholar, Gary completed his MSc and DPhil at University of Oxford in immunology research following his MBBCh medical training at University of the Witwatersrand. His research has been published in numerous leading journals including Nature Communications and Proceedings of the National Academy of Sciences.

Dr. Huang's research was supported by numerous awards including American College of Allergy, Asthma and Immunology, Wellcome Trust and James Martin 21st Century School. Clinically, Gary specializes in immunology, allergy and internal medicine following his training at University of Pennsylvania and Einstein Philadelphia. He is interested in precision medicine to immunological conditions including autoimmunity, inflammatory bowel diseases, immunity-oncology, allergy, dermatitis, respiratory medicine, drug safety, clinical trial, research and development. Prior to joining Janssen, Gary worked at the R&D of Bristol-Myers Squibb, where he worked on both early and late clinical development.

Education & Training

University of Pennsylvania Health SystemFellowship, Allergy and Immunology, 2015 - 2017
Children's Hospital of PhiladelphiaFellowship, Allergy and Immunology, 2015 - 2017
Albert Einstein Healthcare NetworkChief Residency, Internal Medicine, 2014 - 2015
Albert Einstein Healthcare NetworkResidency, Internal Medicine, 2012 - 2014
Albert Einstein Healthcare NetworkInternship, Internal Medicine, 2011 - 2012
University of OxfordDPhil, Clinical Medicine, Rhodes Scholar, 2006 - 2010
University of Oxford, Green Templeton CollegePh.D., Clinical Medicine, 2006 - 2010
University of OxfordMSc, Integrated Immunology, Rhodes Scholar, 2005 - 2006
University of Oxford, Green Templeton CollegeMSc, Integrated Immunology, 2005 - 2006
University of the WitwatersrandClass of 2003

Certifications & Licensure

PA State Medical License 2014 - 2024
American Board of Allergy and Immunology Allergy & Immunology

Awards, Honors, & Recognition

ACAAI Young Investigator Award American College of Allergy, Asthma and Immunology (ACAAI), 2017
Rhodes Scholarship Rhodes Trust, 2004
Benjamin A Gouley, MD Award (Outstanding Chief Medical Resident) 2015
Outstanding Graduating Resident Award 2014
Frank Hammond Sivitz Memorial Award 2014
AAAAI Chrysalis Project Award 2013
Young Investigator Award Conferences on Retrovirus and Opportunistic Infections (CROI), 2009
British HIV Association (BHIVA) Scientist Scholarship 2009
Best Speaker The 2nd Oxbridge Taiwan Scientific Symposium, 2009
Rhodes Scholarship 2004
Intern of the Year 2004
Denis Goldstein Memorial Medal (Family Medicine) 2003
Jack Distiller Prize (Community Medicine) 2003
Commonwealth Foundation and Edward Boyle Memorial Trust Medical Elective Award 2002
Pharmacia and Upjohn Achievement Award (Best Pre-Clinical Student) 2001
Clive Rosendorff Prize (Clinical Pathophysiology) 2001
City of Johannesburg Community Health Student Prize 2001
HS Ebrahim Memorial Award (Physiology and Biochemistry) 2000
Sanlam Price (Physics and Chemistry) 1999
University Council Merit Scholarship 1999-2001
University Entrance Scholarship 1998
Chung Wah Merit Award (South African Chinese Community Award) 1998
Lo Ming-Yuan Scholarships (South African Chinese Community Award) 1998-1999
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Publications & Presentations

PubMed

1 citations
Qualitative and Psychometric Evaluation of 29-Item Patient-Reported Outcomes Measurement Information System® to Assess General Health-Related Quality of Life in Patien...
Bruce E Sands, Julian Panés, Brian G Feagan, Hongyan Zhang, Marion L Vetter
Value in Health. 2024-09-01
17 citations
Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study.
Laurent Peyrin-Biroulet, Jessica R Allegretti, David T Rubin, Brian Bressler, Matthew Germinaro
Gastroenterology. 2023-12-01
1 citations
Qualitative and psychometric evaluation of the PROMIS®-Fatigue SF-7a scale to assess fatigue in patients with moderately to severely active inflammatory bowel disease.
Brian G Feagan, William J Sandborn, Bruce E Sands, Yan Liu, Marion Vetter
Journal of Patient-Reported Outcomes. 2023-11-14

Journal Articles

The Impact of Reported Beta-Lactam Allergy in Hospitalized Patients with Hematologic Malignancies Requiring Antibiotics
Huang, Clinical Infectious Diseases, 1/16/2018
Discordant impact of HLA on viral replicative capacity and disease progression in pediatric and adult HIV infection
Adland E., P. Paioni, C. Thobakgale, L. Laker, L. Mori, M. Muenchhoff, A. Csala, M. Clapson, J. Flynn, V. Novelli, J. Hurst, V. Naidoo, R. Shapiro, K.H.G. Huang, J. Fr..., PLoS Pathogen, 1/15/2015
Dipstick Proteinuria is an Independent Predictor of High on Treatment Platelet Reactivity in Patients on Clopidogrel, but not Aspirin, Admitted for Acute Cardiovascula...
Davila C.D., F. Vargas, K.H.G. Huang, T. Monaco, A. Dimou, J. Rangaswami, V.M. Figueredo, Platelets, 1/1/2015
Impact of HLA-driven HIV adaptation and of anti-retroviral therapy on HIV virulence
Payne R.P., J. Wright, P.C. Matthews, M. Brockman, Z. Brumme, M. Sinclair, K.H.G. Huang, J. Frater, J.M. Carlson, D. Hackerman, T. Miura, R. Shapiro, B.D. Walker, T. N..., PNAS, 1/16/2014
Statin Use and Its Effects on Skeletal Related Events in Patients with Multiple Myeloma
Madueno, F.M.V., A. Benyounes, G. King, K.H.G. Huang, and G. Varadi, Blood, 1/1/2014
Proteinuria is independently associated with high on treatment platelet reactivity in patients on clopidogrel but not aspirin for the treatment of major adverse cardio...
Davila, C.D., F. Vargas, K.H.G. Huang, T. Monaco, A. Dimou, J. Ragaswami, V Figueredo, Journal of the American College of Cardiology, 1/1/2014
Role of endobronchial ultrasound in the diagnosis and management of bronchogenic cysts: two case descriptions and literature review
Franco-Elizondo, R., S. Patnaik, K.H.G. Huang, J. Mora, Southwest Journal of Pulmonary and Critical Care, 1/1/2014
The impact of obesity on the outcome of status asthmaticus patients admitted to the intensive care unit
Huang, K.H.G., J. Lai, H. Nguyen, J. Rhee, K. Teerapuncharoen, S. Pomerantz, L. Braitman, K.R. Young, G. Eiger, American Journal of Respiratory and Critical Care Medicine, 1/1/2013
Pulmonary lymphangitic carcinomatosis as the primary manifestation of pancreatic adenocarcinoma
Teerapuncharoen K., J. Sta Cruz, K.H.G. Huang, J. Wykretowics, G. Murali, CHEST Journal, 1/1/2013
Hemoconcentration during decongestion therapy in acute decompensated heart failure is associated with decreased mortality in African Americans at a community hospital
Davila, C.D., K.H.G. Huang, S. Katz, G. Pressman, V. Figueredo, Journal of Cardiac Failure, 1/1/2013
The effects of renal function on platelet reactivity in patients treated with clopidogrel and admitted for major cardiovascular events in a community setting
Davila, C.D., F. Vargas, T. Monaco, K.H.G. Huang, D.L. Morris, V.M. Figueredo, C. Witzke, Arteriosclerosis, Thrombosis, and Vascular Biology, 1/1/2013
HIV control through a single nucleotide on the HLA-B locus
Kloverpris, H.N., M. Harndahl, A.J. Leslie, J.M. Carlson, N. Ismail, M. van der Stok, K.H.G. Huang, F. Chen, L. Riddell, D. Steyn, D. Goedhals, C. van Vuuren, J. Frate..., Journal of Virology, 1/1/2012
Steroid induced diabetes and acute exacerbation of chronic obstructive pulmonary disease (aeCOPD)
Lai, J., H. Nguyen, K.H.G. Huang, L. Braitman, G. Eiger, American Journal of Respiratory and Critical Care Medicine, 1/1/2012
Co-operative additive effects between HLA alleles in control of HIV-1
Matthews, P.C., J. Listgarten, J.M. Carlson, R. Payne, K.H.G. Huang, J. Frater, D. Goedhals, D. Steyn, C. van Vuuren, P. Paioni, P. Jooste, A. Ogwu, R. Shapiro, Z. Mnc..., PLoS One, 1/1/2012
Advanced HIV infection is associated with increased viral fitness with both reverting and compensatory mutations
Huang, K.H.G.*, D. Goedhals*, J.M. Carlson, M.A. Brockman, S. Mishra, Z.L. Brumme, S. Hickling, C.S.W. Tang, T. Miura, C. Seebregts, D. Heckerman, T. Ndung'u, B. Walke..., PLoS One, 1/22/2011
HLA-A*74-mediated control of HIV viraemia is independent of its linkage disequilibrium with HLA-B*5703
Matthews, P.C., E. Adland, J. Listgarten, A. Leslie, N. Mkhwanazi, J. Carlson, M. Harndahl, A. Stryhn, R. Payne, A. Ogwu et al, The Journal of Immunology, 1/15/2011
B cell depletion reveals a role for antibodies in the control of chronic HIV-1 infection
Huang, K.H.G.*, D. Bonsall*, A. Katzourakis, E. Thomson, S.J. Fidler, J. Main, D. Muir, J.N. Weber, A.J. Frater, R.E. Phillips, M.O. McClure, G.S. Cooke, and P. Klener..., Nature Communications, 1/19/2010
Prevalence of HIV type-1 drug-associated mutations in pre-therapy patients in the Free State, South Africa
Huang, K.H.G., D. Goedhals, H. Fryer, C. van Vuuren, A. Katzourakis, T. De Oliveira, H. Brown, S. Cassol, C. Seebregts, A. McLean, P. Klenerman, R. Phillips, A.J. Frat..., Antiviral Therapy, 1/1/2009
Full-length characterization of hepatitis C virus subtype 3a reveals novel hypervariable regions under positive selection during acute infection
Humphreys, I., V. Fleming, P. Fabris, J. Parker, B. Schulenberg, A. Brown, C. Demetriou, S. Gaudieri, K. Pfafferott, M. Lucas, J. Collier, K.H.G. Huang, O. Pybus, P. K..., Journal of Virology, 1/1/2009
Increase in pre-therapy HIV drug resistance in South Africa is concentrated amongst patients with low CD4 cell counts
Huang, K.H.G., D. Goedhals, C. van Vuuren, A. Katzourakis, T. De Oliveira, P. Klenerman, R. Phillips, and A.J. Frater, HIV Medicine, 1/1/2008
Longitudinal Red Cell Distribution Width Variation in African Americans with Acute Decompensated Heart Failure is Associated with Increased Readmissions
Davila, C.D., M. Shah, K.H.G. Huang, V. Figueredo, Journal of Cardiac Failure
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Books/Book Chapters

HIV testing
Chapter: HIV Drug Resistance in Sub-Saharan Africa - Implications for Testing and Treatment
Page 109 - 132Huang, K.H.G., H. Fryer, D. Goedhals, C. van Vuuran, A.J. FraterEditors: R. S. Diaz.InTech, Rijeka, Croatia2012

Abstracts/Posters

A curious case of Evans Syndrome
Huang KHG et al, American College of Physician (ACP), Internal Medicine, Washington, DC, 1/1/2016
Clinical features and outcomes of subclinical pyelonephritis in the renal transplant recipients
Huang KHG et al, Association of Program Directors in Internal Medicine (APDIM) Spring Meeting, Philadelphia, PA, 1/1/2014
Innovative educational intervention to improve internal medicine signouts
Huang KHG, American College of Physicians (ACP), Internal Medicine Meeting 2014, Nashville, TN, 1/1/2014

Lectures

Three Cases of Facial Swelling Initially Mistaken for Bradykinin-Mediated Angioedema
San Antonio, TX - 1/1/2015
QRS duration predicts left ventricular systolic function following ST elevation myocardial infarction
Albert Einstein Medical Center, Philadelphia, PA, 2013, 2014 - 1/1/2014
Advanced HIV infection is associated with increased viral fitness with both reverting and compensatory mutations.
Whistler, BC, Canada - 1/1/2011
The impact of host and therapy mediated selection on HIV-1 evolution
Taiwan Yang-Ming University, Institute of Clinical Medicine, Taipei, Taiwan - 1/1/2010
Bloemfontein Cohort, SA: Investigating molecular epidemiology and CTL selection in advanced AIDS
Boston, MA - 1/1/2009
A critical role for B cells in control of HIV revealed by Rituximab therapy
Montreal, Canada - 1/1/2009
The potency of haematopoietic stem cells and their therapeutic use
Cape Town, South Africa - 1/1/2005
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Other

The Impact of Host and Therapy Mediated Selection on HIV-1 Evolution
Huang KHG, PhD thesis
University of Oxford, Oxford, United Kingdom - 1/1/2010
Human Immune System in Humanised Rag2-/- gamma c-/- Mouse Model: A Histological Analysis Study of the Major Lymphoid Organs
Huang KHG, MSc Dissertation
University of Oxford, Oxford, United Kingdom - 1/1/2006