KristinBHighlandMD

PubMed

• Idiopathic inflammatory myopathies related lung disease in adults.
  Sameep Sehgal, Aditi Patel, Soumya Chatterjee, Anthony P Fernandez, Carol Farver
  The Lancet. Respiratory Medicine. 2024-11-29
• Trained Mesenchymal Stromal Cell-Based Therapy HXB-319 for Treating Diffuse Alveolar Hemorrhage in a Pristane-induced Murine Model.
  Hulya Bukulmez, Adrienne T Dennis, Jane Reese-Koc, Scott F Sieg, Brian Clagett
  Stem Cells. 2024-11-19
• Efficacy and determinants of response to inhaled treprostinil in pulmonary hypertension - interstitial lung disease.
  Bathmapriya Balakrishnan, Jehad Azar, Samar Farha, Alice M Goyanes, James E Lane
  Respiratory Medicine. 2024-10-18

Journal Articles

• PVDOMICS: A multi-center study to improve understanding of pulmonary vascular disease through phenomics  
  Hemnes AR, Beck GJ, Newman JH, Abidov A, Aldred MA, Barnard J, Rosenzweig EB, Borlaug BA, Chung WK, Comhair SAA, Erzurum SC, Frantz RP, Gray MP, Grunig G, Hassoun PM, ..., Circ Res, 1/1/2017
• Pulmonary arterial hypertension treatment with carvedilol for heart failure: a randomized controlled trial  
  Farha S, Syagin D, Park MM, Cheong HI, Asoingh K, Comhair SAA, Stephens OR, Roach EC, Sharp J, Highland KB, DiFilippo FP, Neumann DR, Tang WHW, Erzurum SC, JCI Insight, 1/1/2017
• Pulmonary artery dimensions as a prognosticator of transplant-free survival in scleroderma interstitial lung disease  
  Gleason JB, Patel KB, Hernandez F, Hadeh A, Highland KB, Rahagi F, Mehta JP, Lung, 1/1/2017
• Metabolic and functional evaluation of the heart and lungs in pulmonary hypertension by gated 2-[18F]-Fluoro-2-deoxy-D-glucose positron emission tomography  
  Saygin D, Highland KB, Farha S, Park M, Sharp J, Roach EC, Tank WHW, Thomas JD, Erzurum SC, Neumann DR, DiFilippo FP, Pulmonary Circulation, 1/1/2017
• Inguilinus limosus in pulmonary disease: case report and review of the literature  
  McHugh KE, Rhoads DD, Wilson DA, Highland KB, Richter SS, Procop GW, Diagn Microbiol Infect Dis, 1/1/2016
• 40-year-old woman with progressive shortness of breath, cough and recurrent pneumonia  
  Shabbir Amna, Das, A, Sehgal S, Lau C, Highland KB, Ann Am Thorac Soc, 1/1/2016
• Reversible platypnea-orthodeoxia syndrome from ventilation-perfusion mismatch in interstitial lung disease: a novel etiology  
  Gadre A, Highland KB, Mehta A, Ann Am Thorac Soc, 1/1/2016
• A 26-year-old woman with systemic lupus erythematosus presenting with orthopnea and restrictive lung impairment  
  Panchabhai TS, Bandyopadhyay D, Highland KB, Chaisson NF, Aboussouan LS, Chest, 1/1/2016
• Lymphocytic interstitial pneumonia  
  Panchabhai TS, Farver C, Highland KB, Clin Chest Med, 1/1/2016
• Mycopheonolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease: Scleroderma lung study II (SLS-II), a double-blind, parallel grou...  
  Tashkin DP, Roth MD, Clements PJ, Furst DE, Khanna D, Kleerup EC, Goldin J, Arriola E, Volkmann ER, Kafaja S, Silver R, Steen V, Strange C, Wise R, Wigley F, Mayes M, ..., Lancet Respiratory Medicine, 1/1/2016
• Cutaneous hypersensitivity and eosinophilia associated with treprostinil  
  Das A, Shabbir A, Sehgal S, Highland KB, Pulmonary Pharmacology & Therapeutics, 1/1/2015
• Outcome measures for clinical trials in interstitial lung diseases  
  Lammi MR, Baughman RP, Birring SS, Russell AM, Ryu JH, Scholand M, Distler O, LeSage D, Sarver C, Antoniou K, Highland KB, Lasky JA, Wells AU, Saketoo LA, Cur Respir Med Rev, 1/1/2015
• Expert consensus for performing right heart catheterization for suspected pulmonary arterial hypertension in systemic sclerosis: a Delphi consensus study with cluster ...  
  Avouac J, Huscher D, Furst DE, Opitz CF, Distler O, Allanore Y, for the EPOSS group, Ann Rheum Dis, 1/1/2014
• Ratonale for anticoagulant therapy of pulmonary fibrosis  
  Bogatkevich GS, Nietert PJ, Silver RM, Highland KB, Am J Respir Crit Care Med, 1/1/2014
• Recent advances in scleroderma-associated pulmonary hypertension  
  Highland KB, Cur Opin Rheumatol, 1/1/2014
• Pulmonary involvement in Sjögren’s syndrome  
  Kreider M, Highland K, Semin Respir Crit Care Med, 1/1/2014
• Concomitant sarcoidosis and a connective tissue disease: Review of the clinical findings and postulations concerning their association  
  Judson MA, Shapiro L, Freitas S, Polychronopoulos VS, Highland KB, Respiratory Medicine, 1/1/2013
• Executive summary Monitoring of Non-steroidal immunosuppressive drugs in lung disease and lung transplant patients: ACCP Evidence-Based Clinical Practice Guidelines  
  Baughman R, Meyer K, Nathanson I, Angel L, Bhorade S, Chan K, Culver D, Harrod C, Hayney M, Highland K, Limper A, Patrick H, Strange C, Whelan T, CHEST, 1/1/2012
• Monitoring of Non-steroidal immunosuppressive drugs in lung disease and lung transplant patients: ACCP Evidence-based clinical practice guidelines  
  Baughman R, Meyer K, Nathanson I, Bhorade S, Chan K, Culver D, Harrod C, Hayney M, Highland K, Limper A, Patrick H, Strange C, Whelan T, CHEST, 1/1/2012
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  Bogatkevich GS, Highland KB, Akter T, Silver RM, Pulmonary Medicine, 1/1/2012
• Dihydrosphingosine 1-Phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels  
  Bu S, Asano Y, Bunor A, Highland K, Hant F, Trojanowska M, Arthritis and Rheumatism, 1/1/2010
• Pulmonary involvement in Sjogren syndrome  
  Kokosi M, Riemer EC, Highland KB, Clinics in Chest Medicine, 1/1/2010
• Inhaled iloprost for sarcoidosis associated pulmonary hypertension  
  Baughman RP, Judson MA, Highland K, Kwon S, Craft N, Engel PJ, Sarcoidosis vasculitis and diffuse lung diseases, 1/1/2009
• Clinical Profile of Anti-PL-12 Autoantibody: Cohort Study and Review of the Literature  
  Kalluri M, Sahn SA, Oddis CV, Gharib SL, Christopher-Stine L, Danoff SK, Casciola-Rosen L, Hong G, Dellaripa PF, Highland KB, Chest, 1/1/2009
• Limitations to the Six-Minute Walk Test in Interstitial Lung Disease and Pulmonary Hypertension in Scleroderma  
  Garin MC, Highland KB, Silver RM, Strange C, J Rheum, 1/1/2009
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Books/Book Chapters

• Pulmonary Hypertension and Interstitial Lung Disease 
  Chapter: Interstitial lung disease-associated pulmonary hypertension in the connective tissue disorders 
  Page 165 - 180Bandyopadhyay D, Panchabhai TS, Highland KBEditors: Baughman RP, Carbone RG, Nathan SD.Springer InternationalEdition 2nd,2017
• Pulmonary Manifestations of Rheumatic Disease 
  Chapter: Pulmonary manifestations of sarcoidosis 
  Page 95 - 121Highland KB, Culver DAEditors: Dellaripa P, Fischer A, Flaherty K.2014
• Pulmonary Manifestations of Rheumatic Disease 
  Chapter: Pulmonary manifestations in mixed connective tissue disease 
  Page 73 - 82Highland KB, Siver RMEditors: Dellaripa P, Fischer A, Flaherty K.2014
• Translational Vascular Medicine 
  Chapter: Understanding the pathobiology of pulmonary vascular disease: 5th International Workshop on Cardiovascular biology and medicine 
  Highland KBEditors: D. Abraham et al.Springer-Verlag London Limited2012
• Clinical Respiratory Medicine 
  Chapter: Holmes A. Pulmonary Hypertension 
  Page 710 - 721Highland KBEditors: Spiro SG, Silvestri GA, Agusti A.Elsevier Saunders, Philadelphia, PAEdition 4th,2012
• Clinics in Chest Medicine 
  Editors: Highland KB.2010
• Advances in Pulmonary Hypertension 
  Editors: Highland KB.2008
• Oxford American Handbook of Pulmonary Medicine 
  Chapter: Immunosuppressive Therapy 
  Page 697 - 705Highland KBEditors: Kevin Brown, Teofilo L. Lee-Chiong.Oxford UP, Oxford, United Kingdom2008
• Diffuse Lung Disease: a practical approach 
  Chapter: Giant cell interstitial pneumonitis caused by cobalt exposure 
  Page 277 - 278Highland KBEditors: Baughman and du Bois.Oxford University Press, New York, NY2004
• Diffuse Lung Disease: a practical approach 
  Chapter: Respiratory involvement in inflammatory bowel disease 
  Page 278 - 280Highland KBEditors: Baughman and du Bois.Oxford University Press, New York, NY2004
• Diffuse Lung Disease: a practical approach 
  Chapter: Chronic beryllium disease 
  Page 280 - 282Highland KBEditors: Baughman and du Bois.Oxford University Press, New York, NY2004
• MKSAP (Medical Knowledge Self-Assessment Program) 13: Pulmonary Medicine and Critical Care 
  Chapter: Cough 
  Page 1 - 3Highland KBEditors: Epstein and Hansen-Flaschen.Philadelphia, PA2004
• MKSAP (Medical Knowledge Self-Assessment Program) 13: Pulmonary Medicine and Critical Care 
  Chapter: Dyspnea 
  Page 3 - 4Highland KBEditors: Epstein and Hansen-Flaschen.Philadelphia, PA2004
• MKSAP (Medical Knowledge Self-Assessment Program) 13: Pulmonary Medicine and Critical Care 
  Chapter: Pulmonary rehabilitation 
  Highland KBEditors: Epstein and Hansen-Flaschen.Philadelphia, PA2004
• Scleroderma – From Pathogenesis to Comprehensive Management 
  Chapter: Progressive interstitial lung disease nonresponsive to cyclophosphamide 
  Page 707 - 712Silver KC, Highland KB, and Silver RMEditors: Varga J, Denton CP, Wigley FM, Allanore Y, Kuwana M.Springer, New York, NYEdition 2nd,
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Abstracts/Posters

• Baseline and demographic data of the first 150 patients from SPHERE (Uptravi® [SelexiPag] tHe usErs dRug rEgistry)
  Chin KM, Highland KB, Kim NH, Chakinala MM, Hemnes AR, Farber HW, Zhao C, Keating M, Colvin J, Hartline B, McLaughlin V, World Symposium on Pulmonary Hypertension, Nice, France, 1/27/2018
• Characteristics of patients with CTD-associated PAH treated with selexipag in the real-world setting: interim data from the SPHERE registry
  Highland KB, Farber HW, Kim NG, Chin KM, Hemnes AR, Chakinala MM, Zhao C, Keating M, Hartline B, McLaughlin V, International Society for Heart & Lung Transplantation, Nice, France, 1/1/2018
• Mepolizumab for refractory asthma in eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
  Saygin D, Arunachalam A, Boyle M, McCarroll S, Micklewright S, Erzurum SC, Highland K, Khatri SB, ATS, Washington, DC, 1/23/2017
• Double aortic arch causing dyspnea in a middle aged woman
  Venkata Subramani, Mrinalini, Highland KB, ATS, Washington, DC, 1/23/2017
• Accuracy of Accelerometry (Fitbit® ChargeHRTM) Measured Distance and Heart Rate in Patients with Pulmonary Arterial Hypertension
  Chowdhury A, Sehgal S, Rabih F, Highland KB, ATS, Washington, DC, 1/22/2017
• Agreeability between patient and physician assessment of WHO functional class and visual analog scale in pulmonary arterial hypertension
  Rabih Fadi, Sehgal S, Chowdhury A, Gadre A, Highland K, ATS, Washington, DC, 1/22/2017
• Fitbit vs six minute walk in PAH
  Sehgal S, Chowdhury A, Rabih F, Gadre A, Highland KB, ATS, Washington, DC, 1/22/2017
• Accuracy of accelerometer (Fitbit® Charge HRTM) measured disgtance and heart rate in patients with pulmonary arterial hypertension
  Chowdhury A, Sehgal S, Rabih F, Gadre A, Highland KB, ATS, Washington, DC, 1/22/2017
• Uptravi® (SelexiPag): tHe usErs dRug rEgistry (SPHERE): A US-based prospective drug registry of selexipag in clinical practice
  Chakinala MM, Hemnes AR, Highland K, Kim NH, Farber HW, Chin K, Keating M, Zhao C, Hartline B, McLaughlin V, ATS, Washington, DC, 1/21/2017
• Pulonary arterial hypertension treatment with carvedilol for heart failure
  Farha S, Saygin D, Park M, Roach C, Comjair SA, Highland K, Hammel J, Newmann D, DiFilippo F, Tang WHW, Erzurum S, ATS, Washington, DC, 1/21/2017
• Comparing pulmonary arterial hypertension-related hospitalizations between hypothetical commercial and Medicare patients using a decision tree model
  Highland KB, Cole M, Bilar P, Tsang Y, Drake W, ISPOR (International Society for Pharmacoeconomics and Outcomes Research) 22nd Annual International Meeting, Boston, MA, 1/20/2017
• Decreasing Length of Stay and Pulmonary Arterial Hypertension Related Hospitalizations with Macitentan Using a Decision Tree Model in a Medicare Population
  Highland KB, Bilir A, Cole MR, Pruitt J,  Drake W, ATS, Washington, DC, 1/20/2017
• Reducing Pulmonary Arterial Hypertension-Related Hospitalizations and Length of Stay with Macitentan Using a Decision Tree Model
  Highland KB, Cole MR, Tseng, Y, Bilar A, Drake W, PH Forum, Vienna, Austria, 1/9/2017
• Uptravi® (SelexiPag): tHe usErs dRug rEgistry (SPHERE) - A US-Based, Prospective Drug Registry of Selexipag in Clinical Practice
  Chakinala MM, Hemnes A, Highland KB Kim NH, Farber H, Chin K, Keating M, Zhao C, Hartline B, and McLaughlin V, PHPN, North Bethesda, MD, 1/5/2017
• Outcomes in lung transplant recipients from donors with bacterial meningitis
  Grewal HS, Tsuang W, Lane C, Turowski T, Highland K, Olufemi A, Mehta AC, Koval C, McCurry K, Budev M, ISHLT (International Society for Heart & Lung Transplantation), San Francisco, CA, 1/5/2017
• Safety and suitability of dabigatran etexilate to inhibit thrombin in scleroderma-associated interstitial lung disease: a preliminary report
  Silver RM, Atanhelishvili I, Kajdasz K, Wilson DA, Nietert PJ, Huggins TJ, Highland K, Bogatkevich G, 15th International Scleroderma Workshop, Pittsburgh, PA, 1/5/2017
• N-termial pro-brain natriuretic peptide is disproportionately elevated in scleroderma associated pulmonary arterial hypertension compared to idiopathic pulmonary arter...
  Hannan A, Dweik R, Highland KB, Heresi G, Tonelli A, Messner W, Chatterjee S, ACR, San Diego, CA, 1/1/2017
• Shrinking lung syndrome in systemic lupus erythematosus patients: a diagnosis we should suspect more often
  Lau C, Lopez-Velazquez, Highland KB, ACR, San Diego, CA, 1/1/2017
• Comparison of scleroderma associated isolated pulmonary arterial hypertension and pulmonary hypertension with concomitant interstitial lung disease
  Hannan A, Dweik R, Highland KB, Heresi G, Tonelli A, Messner W, Chatterjee S, ACR, San Diego, CA, 1/1/2017
• Mortality is increased in scleroderma associated pulmonary arterial hypertension patients with younger age, lower systolic blood pressure, and lower cardiac index, but...
  Hannan A, Dweik R, Highland KB, Heresi G, Tonelli A, Messner W, Chatterjee S, ACR, San Diego, CA, 1/1/2017
• Analysis of prognostic determinants of scleroderma-associated pulmonary arterial hypertension and idiopathic pulmonary arterial hypertension
  Hannan A, Dweik R, Highland KB, Heresi G, Tonelli A, Messner W, Chatterjee S, ACR, San Diego, CA, 1/1/2017
• In Depth Analysis of Six Minute Walk Test Parameters in Scleroderma Patients With and Without Pulmonary Hypertension
  Gadre A, Ghattas C, Minai M, Highland KB, American Thoracic Society, San Francisco, CA, 1/1/2016
• Minimizing burden of disease-related hospitalization among pulmonary arterial patients
  Li H, Highland KB, Cole M, Bilir P, Tsang Y, Graper-Naidich A, Kowal S, Drake W, Academy of Managed Care Pharmacy AMCP Nexus, National Harbor, MD, 1/1/2016
• Development of nintedanib as a treatment for systemic sclerosis-associated interstitial lung disease
  Distler J, Cottin V, Distler O, Coeck C, Schmidt S, Highland KB, Wollin L, ACR/ARHP, San Francisco, CA, 1/1/2016
• Young male with a large mediastinal mass – what next?
  Shabbir A, Sehgal S, Highland KB, Society of General Internal Medicine Midwest Regional Meeting, Cleveland, OH, 1/1/2016
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Lectures

• Multidisciplinary consensus and diagnostic dilemma as an interstitial lung disease: A case based approach 
  San Diego, CA - 1/31/2017
• House should follow me PAH patient? Review of notable untraditional outcome measures.: Goal oriented treatment and monitoring in PAH 
  San Diego, CA - 1/29/2017
• Clinical Data in Idiopathic Pulmonary Fibrosis 
  Frankfurt, Germany - 1/28/2017
• Vasculopathy, inflammation and fibrosis in Systemic Sclerosis 
  Washington, DC - 1/23/2017
• Interstitial lung disease: advances in management 
  Washington, DC - 1/21/2017
• Scleroderma Associated Interstitial Lung Disease: Advances in Management 
  Washington, DC - 1/21/2017
• Inside the PAH Physicians Mind 
  San Diego, CA - 1/16/2017
• Diagnosis and Treatment of Comorbidities: Scleroderma 
  Nashville, TN - 1/11/2017
• Understanding ILD and IPF. Overview of ILD, IPF, and connective tissue disease 
  Nashville, TN - 1/10/2017
• An introduction to pulmonary arterial hypertension 
  Niagara Falls, NY - 1/5/2017
• Pulmonary Hypertension in Interstitial Lung Disease 
  Cleveland, OH; Westin, FL - 1/5/2017
• Precision (Personalized) Medicine in Idiopathic Pulmonary Fibrosis 
  Cleveland, OH - 1/5/2017
• Rheumatologic Clues that the Pulmonist Should Not Miss 
  New Haven, CT - 1/2/2017
• Rodnan Skin Scoring 
  Frankfurt, Germany, 2015, 2017 - 1/1/2017
• Insights into CTD-associated Pulmonary Arterial Hypertension 
  Akron, OH, 2016; Uniontown, OH, 2017 - 1/1/2017
• Sjögren’s Syndrome 
  Cincinnati, OH - 1/22/2016
• A Rheumatologist’s Perspective on Pulmonary Arterial Hyupertension 
  Duncansville, PA - 1/21/2016
• Challenges in PH Diagnosis and Classification 
  Cleveland, OH, 2016; Westin, FL, 2016; Abu Dhabi, UAE, 2016 - 1/18/2016
• Real Life Experience with Nintedanib 
  Washington, DC - 1/14/2016
• Insights into Scleroderma Associated Interstitial Lung Disease 
  New Orleans, LA - 1/1/2016
• CTD Related Emergencies in the ICU: Scleroderma Renal Crisis 
  Los Angeles, CA - 1/1/2016
• Interstitial Lung Disease in the Setting of CTD 
  Los Angeles, CA - 1/1/2016
• Multi-disciplinary consensus in interstitial lung disease: A case based approach 
  Los Angeles, CA - 1/1/2016
• Lung Disease in Systemic Sclerosis (SSc): ACR Clinical Research Conference: Lung Disease in Rheumatology 
  Washington, DC - 1/1/2016
• Nintedanib in Idiopathic Pulmonary Fibrosis, Clinical Data 
  Dallas, TX - 1/20/2015
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Other

• Inhibition of Thrombin as a Novel Strategy in the Treatment of Scleroderma-Associated Interstitial Lung Disease, Systemic Sclerosis - An Update on the Aberrant Immune ... 
  Bogatkevich GS, Highland KB, Akter T, Nietert PJ, Atanelishvili I, van Ryn J, Silver RM
  http://www.intechopen.com/books/systemic-sclerosis-an-update-on-the-aberrant-immune-system-and-clinical-features/inhibition-of-thrombin-as-a-novel-strategy-in-the-treatment-of-scleroderma-associated-interstitial-l
  1/1/2012
• Management of pulmonary hypertension in the connective tissue disease 
  Highland KB, PCCU
  http://www.chestnet.org/education/online/pccu/vol17/lessons21_22/
  1/1/2008
• Supraesophageal complications of gastroesophageal reflux disease 
  Highland KB, PCCU
  http://www.chestnet.org/education/online/pccu/vol17/lessons21_22/
  1/1/2003
• Allergic reaction to drug used to treat pulmonary hypertension 
  Das A, Shabbir A, Sehgal S, Highland KB, Atlas of Science
  http://atlasofscience.org/allergic-reaction-to-drug-used-to-treat-pulmonary-hypertension/
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