KirkHShelleyMDPhD

Anesthesiology • New Haven, CT

Professor of Anesthesiology Yale University

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Office
20 York St
New Haven, CT 06510
Phone+1 203-688-4242

Fax+1 203-688-5013

Summary

Dr Kirk Shelley is boarded in Anesthesia and Internal Medicine. He is a Professor in the Department of Anesthesia at Yale University where he heads their Ambulatory Surgical Division. He obtained MD and PhD degrees (biochemistry) from Penn State University. Dr. Shelley's current research focuses on the development of tools for the noninvasive measurement of physiologic parameters.

As an ambulatory anesthesiologist, I am committed to the development of the best possible noninvasive monitoring technology. My focus has been on the photoplethysmographic waveform (PPG). My primary goal has been to understand the physiology that creates the PPG with an emphasis on its venous and respiratory components. My secondary goal is the utilization of this understanding to develop new methods of patient monitoring. I believe that the state-of-the-art digital signal processing methods combined with new understandings of cardiovascular physiology will allow for significant breakthroughs in this field.

Education & Training

New York Presbyterian Hospital (Columbia Campus)Residency, Anesthesiology, 1989 - 1992
Zucker School of Medicine at Hofstra/Northwell at Lenox Hill HospitalResidency, Internal Medicine, 1981 - 1984
Hershey Medical Center, Pennsylvania State UniversityPh.D., Biochemistry, 1976 - 1981
Pennsylvania State University College of MedicineClass of 1981
St. John's UniversityB.S., Chemistry, Magna Cum Laude, 1972 - 1976

Certifications & Licensure

PA State Medical License Current
CT State Medical License 1997 - 2021
American Board of Anesthesiology Anesthesiology

Awards, Honors, & Recognition

The Harvey W. Wiley Lifetime Achievement IAMPOV, 2012
The Harvey W. Wiley Lifetime Achievement Award 2012
Honorable Mention Award for Best Technology Abstract Society for Technology in Anesthesia, 2011
Co-winner of Best Technology Abstract Society for Technology in Anesthesia, 2001
1st Prize for Best Technology Abstract Society for Technology in Anesthesia, 1997
1st Prize for Best Exhibit American Society of Anesthesiologists, 1994
"Most Valuable Player" Award Penn. State University, 1993
1st Prize for Best Scientific Exhibit Anesthesia Patient Safety Foundation, 1993
Meritorious Service Medal USAF, 1989
UpJohn Award for Creative Scholarship Penn State, 1981
Basic Science Research Award Penn State, 1980
Top MD Consumers Checkbook
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Publications & Presentations

PubMed

Assessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis.
Suthawan Anakmeteeprugsa, Antonio Gonzalez-Fiol, Rostislav Vychodil, Kirk Shelley, Aymen Alian
Journal of Clinical Monitoring and Computing. 2024-04-01
2 citations
Signal quality assessment of peripheral venous pressure.
Neng-Tai Chiu, Beau Chuang, Suthawan Anakmeteeprugsa, Kirk H Shelley, Aymen Awad Alian
Journal of Clinical Monitoring and Computing. 2024-02-01
11 citations
Improving pulse oximetry accuracy in dark-skinned patients: technical aspects and current regulations.
Ana M Cabanas, Pilar Martín-Escudero, Kirk H Shelley
British Journal of Anaesthesia. 2023-10-01

Journal Articles

Commentary on Tinker Ready: Automation and Anesthesia
Shelley KH, Health Leaders, 1/1/2015
Management of Comorbidities in Ambulatory Anesthesia: A Review
Dabu-Bondoc, S. and Shelley, K, Ambulatory Anesthesia, 1/1/2015
Off-Label Use of Clinical Monitors: What Happens When New Physiologic Understanding Meets State-of-the-Art Technology" (Editorial)
Shelley, K. and M. Cannesson, Anesth & Analg, 1/1/2014
Photoplethysmography
Alian A, and Shelley K, Practice & Research: Clinical Anaesthesiology, 1/1/2014
Impact of Lower Body Negative Pressure Induced Hypovolemia on Peripheral Venous Pressure Waveform Parameters in Healthy Volunteers
Alian A, Galante N, Stachenfeld N, Silverman D and Shelley K, Physiological Measurement, 1/1/2014
Analysis of plethysmographic waveform changes induced by beach chair positioning under general anesthesia
Zhu R, Atteya G, Shelley KH, Silverman DG, Alian AA, Journal of Clinical Monitoring and Computing, 1/1/2014
New Utility for an Old Tool: Can a Simple Gait Speed Test Predict Ambulatory Surgical Discharge Outcomes?
Charles Odonkor, Robert Schonberger, Feng Dai, Kirk Shelley, David Silverman, and Paul Barash, American Journal of Physical Medicine & Rehabilitation, 1/1/2013
The role of the photoplethysmographic waveform in the care of high risk surgical patients
Kirk H. Shelley M.D, Ph.D., Aymen A. Alian M.D., Adam J. Shelley M.S., Anesthesiology, 1/1/2013
Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and PACU Length of Stay
Susan Dabu-Bondoc, Nalini Vadivelu, Chantelle Shimono, Annette English, Boonsri Kosarussavadi, Feng Dai, Kirk Shelley, and Jessica Feinleib, Anesthesia & Analgesia, 1/1/2013
Respiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform
Aymen A Alian and Kirk H. Shelley, Sensors, 1/1/2012
Detection of 900 ml Blood Withdrawal by Amplitude Modulation Analysis of the Photoplethysmographic Waveform
Christopher G. Scully, Nandakumar Selvaraj, Frederick W. Romberg, Richa Wardhan, John Ryan, John P. Florian, David G. Silverman, Kirk H. Shelley, and Ki H. Chon, Anesthesia & Analgesia, 1/1/2012
Commentary on John Dillion: Seeing the (Green) Light In the OR
Shelley KH, Anesthesiology News, 1/1/2012
Modulation of finger photoplethysmographic traces during forced respiration: Venous blood in motion?
Phillips, J. P., A. Belhaj, K. Shafqat, R. M. Langford, K. H. Shelley and P. A. Kyriacou, Conf Proc IEEE Eng Med Biol Soc, 1/1/2012
Autonomic control mechanism of maximal lower body negative pressure application
Selvaraj, N., K. H. Shelley, D. G. Silverman, N. Stachenfeld and K. H. Chon, Conf Proc IEEE Eng Med Biol Soc, 1/1/2012
Conflict of Interest and the Academic Innovator (Editorial)
James Szocik and Kirk Shelley, Association of University Anesthesiologists Newsletter, 1/1/2011
A novel approach using time-frequency analysis of pulse-oximeter data to detect progressive hypovolemia in spontaneously breathing healthy subjects
Nandakumar Selvaraj, Kirk H. Shelley, David G. Silverman, Nina Stachenfeld, Nicholas Galante, John P. Florian, Yitzhak Mendelson, and Ki H. Chon, IEEE Transactions on Biomedical Engineering, 1/1/2011
Impact of Central Hypovolemia on Photoplethysmographic Waveform Parameters in Healthy Volunteers Part 1: Time Domain Analysis
Aymen A. Alian, Nicholas J. Galante, Nina S. Stachenfeld, David G. Silverman, and Kirk H. Shelley, Journal of Clinical Monitoring and Computing, 1/1/2011
Is Automation of Anesthesia Inevitable? (Editorial)
Shelley KH, Association of University Anesthesiologists Newsletter, 1/1/2011
Noninvasive Hemodynamic Monitoring
Shelley KH, ASA Newsletter, 1/1/2011
Commentary on Marcus A: Gaming Unit Could Help Prevent Post-procedure Falls
Shelley KH, Anesthesiology News, 1/1/2011
Commentary on Marcus A: Difficult Airway? It’s as Plain as the Nose…
Shelley KH, Anesthesiology News, 1/1/2010
Measuring Venous Oxygen Saturation Using the Photoplethysmographic Waveform
Zachary D Walton, Panayiotis Kyriacou, David G Silverman, & Kirk H Shelley, Journal of Clinical Monitoring and Computing, 1/1/2010
Virtual Environments in Healthcare: Immersion, Disruption, and Flow
Taekman, Jefferey and Shelley, Kirk, International Anesthesiology Clinics, 1/1/2010
Tissue Doppler of Early Mitral Filling Correlates with Simulated Volume Loss in Healthy Subjects
Moore, Chris; Tham, Edward; Samuels, Kathleen; Dziura, James; McNamara, Robert; Stachenfeld, Nina; Shelley, Kirk; & Silverman, David, Academic Emergency Medicine, 1/1/2010
Estimation of respiratory rate from ECG, photoplethysmogram and piezoelectric pulse transducer signals: a comparative study of time-frequency methods
Shishir Dash, Kirk H. Shelley, David G. Silverman, and Ki H. Chon, IEEE Transactions on Biomedical Engineering, 1/1/2010
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Books/Book Chapters

Monitoring Technologies in Acute Care Environments
Chapter: Photoplethysmography: Analysis of the Pulse Oximeter Waveform
Aymen Alian and Kirk ShelleyEditors: Jesse Ehrenfeld and Maxime Cannesson.Springer2014
Physiological Monitoring in the Critical Care Setting (Monitorage des Paramètres Physiologiques en Situation critique)
Chapter: Pulse oximeter waveform: Photoplethysmography
Aymen Alian and Kirk ShelleyEditors: Cannesson M & Lehot JJ.Arnette, Paris2012
The 5-Minute Anesthesia Consult
Chapter: Uremia
Rongjie Jiang and Kirk ShelleyEditors: Nina Singh-Radcliff.Lippincott Williams & Wilkins, Philadelphia, PA2012
Clinical Monitoring
Chapter: Pulse Oximeter Waveform: Photoelectric Plethysmography
Shelley, Kirk and Shelley, StaceyEditors: Carol Lake, Roberta Hines and Casey Blitt.W.B. Saunders Company, Philadelphia, PA2001
Clinical Monitoring
Chapter: Monitoring in Unusual Environments
Shelley, Kirk, Shelley, Stacey and Bell, CharlotteEditors: Carol Lake, Roberta Hines and Casey Blitt.W.B. Saunders Company, Philadelphia, PA2001
Blood: Hemostasis, Transfusion, and Alternatives in the Perioperative Period
Chapter: Perioperative Blood Loss
Shelley, Kirk and Hensley, FrederickEditors: Carol L. Lake, M.D. and Roger A. Moore, M.D..Raven Press, New York, NY1995
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Abstracts/Posters

Effect of Pneumoperitoneum During Laparoscopic Surgery on Plethysmographic and Peripheral Venous Pressure Waveforms
Mueez Qureshi, B.S., Zingg Tobias M.D., Kirk Shelley M.D. Ph.D., and Aymen Alian M.D., Society for Technology in Anesthesia (STA) Annual Meeting, Tucson, AZ, 1/1/2015
Pulse Oximetry-Derived Left Ventricular Function Data Sets
Terence Rafferty, MD, MBA, Kirk Shelley, MD, PhD, Aymen Alian, MD, Society for Technology in Anesthesia (STA) Annual Meeting, Tucson, AZ, 1/1/2015
Normalizing PPG Signals to the AC Component – Applications for Monitoring Volume Loss
David G. Silverman, M.D.,I-Hsun Liang, M.D., Aymen Alian, M.D., Kirk Shelley, M.D., Ph.D., and Nina Stachenfeld, Ph.D., Society for Technology in Anesthesia (STA) Annual Meeting, Tucson, AZ, 1/1/2015
Temporal, Amplitude and Complexity Comparison of the Photoplethysmographic Waveforms from Commercial Pulse Oximeters
Matthew Mikhail, Kirk Shelley and Aymen Alian, IAMPOV, Tokyo, Japan, 1/1/2015
Monitoring Arterial And Venous Volume Response To Release of Lower Body Negative Pressure (LBNP) Using Photoplethysmograph (PPG)
Vicki Bing, B.S., I-Hsun Liang, M.D., Siqin Nie, M.D., Aymen Alian, M.D., Kirk Shelley, M.D., Ph.D., Nina Stachenfeld, Ph.D., David G. Silverman, M.D., Society for Technology in Anesthesia (STA) Annual Meeting, Orlando, FL, 1/1/2014
Optimizing Measurement of The AC Component (Height) of the Photoplethysmographic (PPG) Signal
Siqin Nie, MD, I-Hsun Liang, MD, Feng Dai, Ph.D, Nick Florio, BS, Vicki Bing, BS, Kirk H. Shelley, MD/Ph.D, Aymen Alian, MD, David G. Silverman, MD, Society for Technology in Anesthesia (STA) Annual Meeting, Orlando, FL, 1/1/2014
Autocentering The PPG Waveform: Is It Worth The Price?
Siqin Nie, M.D., Nina Stachenfeld, Ph.D., Aymen Alian, M.D., Kirk Shelley, M.D., Ph.D., David G. Silverman, M.D., Society for Technology in Anesthesia (STA) Annual Meeting, Orlando, FL, 1/1/2014
Integrated Monitoring of Arterial And Venous Components of Plethysmographic Signals
I-Hsun Liang, M.D., Siqin Nie, M.D. , Samrawit Goshu, M.D., Saeeda Qadri, M.D. , Nina Stachenfeld, Ph.D. , Aymen Alian, M.D., Kirk Shelley, M.D., Ph.D., Society for Technology in Anesthesia (STA) Annual Meeting, Orlando, FL, 1/1/2014
Impact of Incentive Spirometry (IS) Breathing on Infra Red Finger Photoplethysmographic (IR-PPG) Waveform Provided by the Sentec Digital Monitor
Aymen Alian MD, Adam J Shelley MS, Lee Hingula MD, Lila Baaklini MD,David G Silverman, MD, Kirk H Shelley MD, PhD., Society for Technology in Anesthesia (STA) Annual Meeting, Orlando, FL, 1/1/2014
Impact of Different Breathing Patterns on Peripheral Venous Pressure (PVP)
I-Hsun Liang, MD, Siqin Nie MD, Lee Hingula MD, Adam J Shelley MS, David G Silverman, MD, Kirk H Shelley MD, PhD, Aymen A Alian MD, Society for Technology in Anesthesia (STA) Annual Meeting, Orlando, FL, 1/1/2014
Impact of Different Breathing Patterns on Finger Photoplethysmographic (PPG) Parameters
Lee Hingula, MD, Siqin Nie, MD, Lila Baaklini MD, Adam J Shelley MS, Kirk H Shelley, MD, PhD, Aymen A Alian, MD, Society for Technology in Anesthesia (STA) Annual Meeting, Orlando, FL, 1/1/2014
Impact of Hydrostatic Pressure on Peripheral Venous Pressure Measurements
Terence Rafferty, MD, Reim Alian, Kirk Shelley, MD, PhD and Aymen Alian, MD, Society for Technology in Anesthesia (STA) Annual Meeting, Orlando, FL, 1/1/2014
Analysis of the modulation of the IR finger photoplethysmographic waveform by incentive spirometry
Aymen A Alian, Adam J Shelley, Lee Hingula, David G Silverman, Kirk H Shelley, American Society of Anesthesiologists (ASA), New Orleans, LA, 1/1/2014
Analysis of Muller, Valsalva and Incentive spirometry breathing patterns on peripheral venous pressure
Aymen A Alian, Lee Hingula, Adam J Shelley, Kirk H Shelley, David G Silverman, American Society of Anesthesiologists (ASA), New Orleans, LA, 1/1/2014
Analysis of Muller, Valsalva and Incentive spirometry breathing patterns on finger photoplethysmographic (PPG) waveform
Lee Hingula, Adam J Shelley, Kirk H Shelley, David G Silverman, Aymen A Alian, American Society of Anesthesiologists (ASA), New Orleans, LA, 1/1/2014
The Cost of Autocentering the PPG Waveform: Is It Worth The Price?
Siqin Nie, M.D., I-Hsun Liang, M.D., Nina Stachenfeld, Ph.D., Aymen A. Alian, M.B.,B.Ch., M.D., Kirk H. Shelley, M.D., Ph.D., David G. Silverman, M.D, American Society of Anesthesiologists (ASA), New Orleans, LA, 1/1/2014
Measuring the AC Component (Height) of the Photoplethysmographic Signal
Siqin Nie, M.D., I-Hsun Liang, M.D., Feng Dai, Ph.D., Nick Florio, B.S., Vicki Z. Bing, B.S., Kirk H. Shelley, M.D., Ph.D., Aymen A. Alian, M.B.,B.Ch., M.D., David G. ..., American Society of Anesthesiologists (ASA), New Orleans, LA, 1/1/2014
Photoplethysmographic Delineation of Arterial and Venous Volume Responses to Release of Lower Body Negative Pressure (LBNP)
Vicki Zhu Jun Bing, B.S., I-Hsun Liang, M.D., Siqin Nie, M.D., Aymen A. Alian, M.B.,B.Ch., M.D., Kirk H. Shelley, M.D., Ph.D., Nina Stachenfeld, Ph.D., David G. Silver..., American Society of Anesthesiologists (ASA), New Orleans, LA, 1/1/2014
Distinguishing Arterial And Venous Components of Plethysmographic Signals
I-Hsun Liang, M.D., Siqin Nie, M.D., Samrawit A. Goshu, M.D., Saeeda Qadri, M.D., Nina Stachenfeld, Ph.D., Aymen A. Alian, M.B.,B.Ch., M.D., Kirk H. Shelley, M.D., Ph...., American Society of Anesthesiologists (ASA), New Orleans, LA, 1/1/2014
Tracking intravascular volume changes in children during spinal fusion surgery utilizing frequency analysis of plethysmographic waveforms
Aymen Alian MD, Gourg Atteya MD, Thomas Golembeski MD, Tal Levy MD, Jill Arthur MD, Kirk Shelley MD, PhD, STA Annual meeting, Phoenix, AZ, 1/1/2013
Walk This Way: Utility of a Mobility-Performance Test in a Prediction Model of Ambulatory Surgical Outcomes
Charles A. Odonkor, BSc, MA; Robert B. Schonberger, MD; Feng Dai, PhD; Kirk H. Shelley, MD, PhD; David G. Silverman, MD; Paul G. Barash, MD, AAP Annual Meeting, New Orleans, LA, 1/1/2013
Frequency analysis of plethysmographic and arterial waveforms during spinal fusion surgery; a novel method of assessment of intravascular blood volume
Gourg Atteya, Nishanthi Kandiah, Thomas Golembeski, Kirk Shelley, Aymen A. Alian, SPA annual meeting, Red Rock Resort, Las Vegas, NV, 1/1/2013
Assessment of intravascular volume status in spontaneously breathing patients utilizing photoplethysmographic (PPG) induced respiratory variability
Aymen A. Alian, Nyasha George, Gourg Atteya, Kirk H. Shelley, 5th All Africa Anesthesia Conference, Egypt, 1/1/2013
Plethysmographic and arterial waveform analysis during spinal fusion surgery using frequency analysis as a method of detecting changes in intravascular volume status
Gourg Atteya, Nishanthi Kandiah, Kirk Shelley, Aymen A. Alian, 5th All Africa Anesthesia Conference, Egypt, 1/1/2013
Plethysmographic and arterial waveform analysis during spinal fusion surgery using frequency analysis as a method of detecting changes in pre-load (venous) volume status
Gourg Atteya, Nishanthi Kandiah, Thomas Golembeski, Brian Smith, Kirk Shelley, Aymen A. Alian, 6th Triennial Congress of the International Federation of Paediatric Orthopaedic Societies, Toronto, Ontario, Canada, 1/1/2013
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Lectures

Pediatric fluid management using the pulse oximeter waveform (PPG)
Storrs, CT - 1/10/2015
Pulse Oximeter Waveform (PPG): Beyond oxygen saturation and heart rate determination…
City University, London, England - 1/7/2014
Advances in Photoplethysmographic Analysis
Las Vegas, NV - 1/1/2014
Pulse Oximeter Waveform Analysis
Union Hospital, Tongi Medical College, Huazhong University in Beijing China - 1/1/2013
Non-invasive Hemodynamic Monitoring: Clinical Use of Photoplethysmography
Xiang-Ya School of Medicine in Changsha, China - 1/1/2013
Future clinical use of photoplethysmography
Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea - 1/1/2013
Venous/Arterial Compliance Ratio Calculation
Phoenix, AZ - 1/1/2013
hotoplethysmography to Detect Vascular Compliance
Yale, New Haven, CT - 1/1/2012
Transforming a Bedside Observation to a Clinical Monitor: What is the Path Forward?
Boston, MA - 1/1/2012
Unrealized Opportunities in Photoplethysmography
Vancouver, Canada - 1/1/2011
The Future of Noninvasive Cardiac Monitoring
Vancouver, Canada - 1/1/2011
Anesthesia and the Elderly
Yale University - 1/1/2010
Photoplethysmography: beyond the calculation of SpO2 and pulse rate
Multiple locations, 2007, 2009 - 1/1/2009
What’s new in Pulse Oximetry?
London, England - 1/1/2007
Atlas of Pulse Oximeter Waveforms
Chicago, IL - 1/1/2006
Ambulatory Operating Room Leadership & Management. Lessons learned…
Boston University, Boston, MA - 1/1/2006
Analysis of the photoplethysmographic waveform: Designing the 3rd generation of pulse oximeters
Hanover, NH - 1/1/2006
Case studies in Pulse Oximetry
Henry Ford Hospital, Detroit, MI - 1/1/2005
Research Application of Laser Doppler & Plethysmographic Monitoring of Blood Flow
Yale University - 1/1/2004
The Use of PDAs in the OR
1/1/2003
Internet communication technology
1/22/1999
Information management technology
1/21/1998
Plethysmograph Technology
Hershey Medical Center - 1/25/1995
New Tools of the Trade
Hershey Medical Center - 1/25/1994
Computer Aided Instruction
Washington, DC - 1/12/1994
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Other

Panel Looks Forward to Role of Automation in Anesthesia
Anesthesiology News
1/1/2012
Q&A With STA President Kirk Shelley, MD, PhD
Anesthesiology News
1/1/2011
Non-invasive clinical monitoring
Ask The Experts (OpenAnesthesia.org : IARS:PodCast)
http://openanesthesia.org/index.php?title=Audio/Video#June_2011:__Non-invasive_clinical_monitoring
1/1/2011
Diving deep into a data wave to make surgery safer
Medicine@Yale
http://www.medicineatyale.org/v2i3_may_june2006/datawave.html
1/1/2006
Virtual Medical Conferences Would Allow “Attendees” to Stay at Home
Anesthesiology News
1/1/2006
Anesthesiologist finds a new way to manage blood loss in the operating room
Yale Medicine
http://yalemedicine.yale.edu/ym_au06/rounds.html
1/1/2006
Medical Jargon: It’s Still Mostly Greek to Your Patients
Anesthesiology News
1/1/2005
Detecting Blood Loss - A simple finger-clip device is able to monitor blood loss accurately -- without the need for more invasive or expensive procedures
MIT Technology Review
http://www.technologyreview.com/biomedicine/16019/
1/1/2005
Pulse Oximetry Monitoring at the Forehead May Be Better
Anesthesiology News
1/1/2004
Implementation of Cognitive Science in Anesthesiology Education and Training
Mentzer S, Murray WB, Schneider AJL, Marshall WK, Shelley KH, Taekman J, Vaduva S, Foster PA and Roeckel M
San Francisco, CA - 1/1/1994
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Press Mentions

Deep Neural Networks Can Predict in-Hospital MortalityMay 10th, 2017

Professional Memberships

American Society of Anesthesiologists
Member
International Anesthesia Research Society - IARS
Member
Society for Technology in Anesthesia
Past President

External Links

Google Scholarhttp://scholar.google.com/citations?user=aiPryaQAAAAJ&hl=en