KimberlyStegmaierMD

PubMed

• 169 citations
  Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry.
  Adam D. Durbin, Mark W. Zimmerman, Neekesh V. Dharia, Brian J. Abraham, Amanda Balboni Iniguez
  Nature Genetics. 2018-08-20
• 1137 citations
  Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.
  Robin M. Meyers, Jordan Bryan, James M. McFarland, Barbara A. Weir, Ann E. Sizemore
  Nature Genetics. 2017-10-30
• 29 citations
  RAD21 is a driver of chromosome 8 gain in Ewing sarcoma to mitigate replication stress.
  Xiaofeng A. Su, Duanduan Ma, James V. Parsons, John M. Replogle, James F. Amatruda
  Genes & Development. 2021-03-25

Journal Articles

• Creatine Kinase Pathway Inhibition Alters GSK3 and WNT Signaling in EVI1-Positive AML  
  Kimberly Stegmaier, MD, Nature
• Selective Gene Dependencies in MYCN-Amplified Neuroblastoma Include the Core Transcriptional Regulatory Circuitry  
  William C Hahn, Todd R Golub, A Thomas Look, Adam D Durbin, Neekesh V Dharia, Kimberly Stegmaier, Nature
• Genome-Scale CRISPR-Cas9 Screen Identifies Druggable Dependencies in TP53 Wild-Type Ewing Sarcoma  
  Loren D. Walensky, Kimberly Stegmaier, The Journal of Experimental Medicine
• Targeted Therapy for Fusion-Driven High-Risk Acute Leukemia  
  Kimberly Stegmaier, Yana Pikman, Blood
• Author Correction: EWS–FLI1 Increases Transcription to Cause R-loops and Block BRCA1 Repair in Ewing Sarcoma  
  Kimberly Stegmaier, Stephen L Lessnick, Jeffrey A Toretsky, Nature
• Integrated Genetic and Pharmacologic Interrogation of Rare Cancers  
  Andrew L Hong, Katherine A Janeway, Brian D Crompton, Kimberly Stegmaier, Levi A Garraway, Alanna J Church, Stuart L Schreiber, William C Hahn, Nature
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Abstracts/Posters

• Targeting the Activating Mutations of NOTCH1 in T-Cell Lymphoblastic Leukemia with a New SERCA Inhibitor CAD204520
  Kimberly Stegmaier, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Targeting Salt-Inducible Kinase 3 As a Therapeutic Approach for Acute Myeloid Leukemia
  Kimberly Stegmaier, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Core Transcriptional Regulatory Circuitries in AML
  Kimberly Stegmaier, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Lectures

• Drugging the Undruggable 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-Risk Leukemias: A Report from the LEAP ConsortiumClinically Relevant Abstract 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018