KimENicholsMD

PubMed

• 221 citations
  Mg2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D
  Benjamin Chaigne-Delalande, Feng-Yen Li, Geraldine M. O’Connor, Marshall J. Lukacs, Ping Jiang
  Science. 2013-07-12
• 870 citations
  SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation preve...
  Jens M. Chemnitz, Richard V. Parry, Kim E. Nichols, Carl H. June, James L. Riley
  Journal of Immunology. 2004-07-15
• 383 citations
  Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1.
  Kim E. Nichols, John D. Crispino, Mortimer Poncz, James G. White, Stuart H. Orkin
  Nature Genetics. 2000-03-01

Journal Articles

• Clinical Genome Sequencing Uncovers Potentially Targetable Truncations and Fusions of MAP3K8 in Spitzoid and Other Melanomas  
  Alberto Pappo, Armita Bahrami, Elizabeth M Azzato, Kim E Nichols, David W Ellison, Nature
• Polygenic Determinants for Subsequent Breast Cancer Risk in Survivors of Childhood Cancer: The St Jude Lifetime Cohort Study (SJLIFE)  
  Kim E Nichols, Melissa M Hudson, Chimene A Kesserwan, Matthew J Ehrhardt, James R Downing, Clinical Cancer Research
• The Influence of Adolescence on Parents’ Perspectives of Testing and Discussing Inherited Cancer Predisposition  
  Melissa A Alderfer, Carol A Ford, Corinna L Schultz, Kim E Nichols, Kristin Zelley, Robert B Lindell, Journal of Genetic Counseling
• Reply to: Germline mutations in predisposition genes in children with cancer  
  Zhang J, Nichols KE, Downing J, New Engl J Med, 1/1/2016
• Stepwise phosphorylation of p65 promotes NF-?B activation and NK cell responses during target cell recognition  
  Kwon HJ, Choi GE, Ryu S, Kwon SJ, Kim SC, Booth C, Nichols KE, Kim HS, Nat Commun, 1/1/2016
• Germline ETV6 mutations confer susceptibility to acute lymphoblastic leukemia and thrombocytopenia  
  Topka S, Vijai J, Walsh MF, Jacobs L, Maria A Villano D, Gaddam P, Wu G, McGee RB, Quinn E, Inaba H, Hartford C, Pui CH, Pappo AS, Edmonson M, Zhang M, Stepensky P, St..., PLOS Genetics, 1/1/2015
• Germline Mutations in Predisposition Genes in Pediatric Cancer  
  Zhang J, Walsh MF, Wu G, Edmonson MN, Gruber TA, Easton J, Hedges D, Ma X, Zhou X, Yergeau DA, Wilkinson MR, Vadodaria B, Chen X, McGee RB, Hines-Dowell S, Nuccio R, Q..., New Engl J Med, 1/1/2015
• Germline Genetic Variation in ETV6 and Risk of Childhood Acute Lymphoblastic Leukemia: a Systematic Genetic Study  
  Moriyama T, Metzger ML, Wu G, Nishii R, Qian M, Devidas M, Yang W, Cheng C, Quinn E, Raimondi S, Gastier-Foster JM, Raetz E, Larsen E, Martin PL, Bowman WP, Winick N, ..., Lancet Oncol, 1/1/2015
• Parent decision-making around genetic testing of children for germline TP53 mutations  
  Alderfer MA, Zelley K, Lindell RB, Novokmet A, Mai PL, Garber JE, Nathan D, Scollon S, Chun NM, Patenaude AF, Ford JM, Plon SE, Schiffman JD, Diller LR, Savage SA, Mal..., Cancer, 1/1/2015
• Hemophagocytic lymphohistiocytosis caused by dominant negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion  
  Spessott WA, Sanmillan ML, McCormick ME, Patel N, Villanueva J, Zhang K, Nichols KE, Giraudo CG, Blood, 1/1/2015
• Bilateral pheochromocytomas, hemihyperplasia, and subtle somatic mosaicism: the importance of detecting low-level uniparental disomy  
  Kalish JM, Conlin LK, Mostoufi-Moab S, Wilkens AB, Mulchandani S, Zelley K, Kowalski M, Bhatti TR, Russo P, Mattei P, Mackenzie WG, LiVolsi V, Nichols KE, Biegel JA, S..., Am J Med Genet, 1/1/2013
• Treatment of Epstein-Barr virus-induced haemophagocytic lymphohistiocytosis with rituximab-containing chemo-immunotherapeutic regimens  
  Chellapandian D, Das R, Zelley K, Wiener SJ, Zhao H, Teachey DT, Nichols KE; EBV-HLH Rituximab Study Group, Br J Haematol, 1/1/2013
• Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy  
  Teachey DT, Rheingold SR, Maude SL, Zugmaier G, Barrett DM, Seif AE, Nichols KE, Suppa EK, Kalos M, Berg RA, Fitzgerald JC, Aplenc R, Gore L, Grupp SA, Blood, 1/1/2013
• Clinical features of three girls with mosaic genome-wide paternal uniparental isodisomy  
  Kalish JM, Conlin LK, Bhatti TR, Dubbs HA, Harris MC, Izumi K, Mostoufi-Moab S, Mulchandani S, Saitta S, States LJ, Swarr DT, Wilkens AB, Zackai EH, Zelley K, Bartolom..., Am J Hum Genet, 1/1/2013
• Expansion of somatically reverted memory CD8+ T cells in X-linked lymphoproliferative disease caused by selective pressure from Epstein Barr virus  
  Palendira U, Low C, Bell AI, Ma CS, Abbott RJ, Phan TG, Riminton DS, Choo S, Smart JM, Lougaris V, Giliani S, Buckley RH, Grimbacher B, Alvaro F, Klion AD, Nichols KE,..., J Exp Med, 1/1/2012
• X-linked lymphoproliferative disease (XLP)  
  Bassiri H, Nichols KE, Atlas Genet Cytogenet Oncol Haematol, 1/1/2012
• SAP-mediated inhibition of diacylglycerol kinase alpha regulates TCR-induced diacylglycerol signalling  
  Baldanzi G, Pighini A, Bettio V, Rainero E, Traini S, Chianale F, Porporato P, Filigheddu N, Mesturini R, Song S, Schweighoffer T, Patrussi L, Baldari CT, Zhong XP, va..., J Immunol, 1/1/2011
• X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: A Multicentre Study on the manifestations, management and outcome of the disease  
  Booth C, Gilmour KC, Veys P, Gennery AR, Slatter MA, Chapel H, Heath PT, Steward CG, Smith O, O'Meara A, Kerrigan H, Mahlaoui N, Cavazzana-Calvo M, Fischer A, Moshous ..., Blood, 1/1/2011
• Impaired SLAM-SLAM homotypic interaction between invariant NKT cells and dendritic cells affects differentiation of IL-4/IL-10 secreting NKT2 cells in nonobese diabeti...  
  Baev DV, Caielli S, Ronchi F, Coccia M, Facciotti F, Nichols KE, Falcone M, J Immunol, 1/1/2008
• In FHL4, NK cells pack less of a punch  
  Nichols K, Blood, 1/1/2007
• Selective generation of functionally somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease  
  Ma CS, Pittalugia S, Avery DT, Hare NJ, Maric I, Klion AD, Nichols KE, Tangye SG, J Clin Invest, 1/1/2006
• Signaling via the T cell receptor  
  Singer AL, Jordan MS, Judd BA, Myung PS, Newbrough SA, Nichols KE, Olenchock BA, Peterson EJ, Wu JN, Zhong XP, Koretzky GA, Sci STKE, 1/1/2003
• X-linked lymphoproliferative disease  
  Nichols KE, Gross TG, Immunol Allergy Clin North Am, 1/1/2002
• The expression of WT1 in the differentiation of rhabdomyosarcoma from other pediatric small round blue cell tumors  
  Carpentieri DF, Nichols KE, Chou PM, Matthews M, Pawel B, Huff D, Mod Pathol, 1/1/2002
• CDw150 is a signaling molecule that modulates CD95-mediated apoptosis  
  Sidorenko, SP, Yurchenko ON, Shlapatskaya LN, Mikhalap SV, Berdova AG, Yun TJ, Nichols KE, Clark EA, Exp Oncol, 1/1/2000
• Join now to see all

Books/Book Chapters

• Brain Tumors in Children. 
  Chapter: Predisposition to central nervous system cancers. 
  Broniscer A, Nichols KEEditors: Gajjar A, Reaman GH, Racadio JM, Smith F.Springer Press2016
• Nathan and Oski’s Hematology and Oncology of Childhood 
  Chapter: Genetic predisposition to cancer. 
  Zelley K, Lindell RB, Schiffman JD, Nichols KEEditors: Orkin SH, Nathan DG, Ginsburg D, Look AT, Lux SE.Elsevier Saunders PressEdition 8th,2014
• Immunologic Disorders in Infants and Children, 
  Chapter: The X-linked lymphoproliferative syndromes. 
  Nichols KE, Marsh RMEditors: Stiehm R, Ochs HD, Winkelstein JA.Elsevier Saunders PressEdition 6th,2013
• Cancer Immunology: Translational Medicine from Bench to Bedside. 
  Chapter: Primary immunodeficiencies and cancers. 
  Hedayat M, Al-Herz W, Aghamohammadi A, Nichols KE, Rezaei NEditors: Rezaei N.Springer Press2013
• Retinoblastoma 
  Chapter: The genetics of retinoblastoma: molecular and clinical aspects. 
  Ganguly A, Nichols KEEditors: Ramasubramanian A, Shields CL.Jaypee Brothers Medical Publishers, New Delhi, IndiaEdition 1st,2011
• Childhood Leukemias, 
  Chapter: Inherited predisposition to childhood leukemia. 
  Seif A, Biegel J, Lange BJ, Nichols KEEditors: Pui CH.Cambridge University Press, Cambridge, EnglandEdition 3rd,2010
• Requisites in Pediatrics: Hematology and Oncology. 
  Chapter: Retinoblastoma. 
  Nichols KE, Leahey A, Meadows ATEditors: Brodeur G, Manno C.Elsevier Health Sciences-Mosby Publisher, Philadelphia, PA2007
• Requisites in Pediatrics: Hematology and Oncology. 
  Chapter: The Childhood Histiocytoses: Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis. 
  Goldsmith K, Hogarty M, Nichols KEEditors: Brodeur G, Manno C.Elsevier Health Sciences-Mosby Publisher, Philadelphia, PA2007
• Modern Aspects of Immunobiology. 
  Chapter: Summary of the 13th Nikolas Symposium. The Macrophage and Dendritic Cell Newsletter. 
  Page 3 - 6Nichols KE, Perry VH, Arceci R, Pritchard J, Jaffe R, Egeler RM, Leenen PJM2004
• Leukocyte Typing VII. 
  Chapter: CDw150 modulates CD95-mediated apoptosis. 
  Page 60 - 63Shlapatskaya LM, Berdova GG. Mikhalap SV, Yun TJ, Nichols KE, Clark EA, Sidorenko SPOxford University Press2002
• Leukocyte Typing VII. 
  Chapter: CDw150 association with SHIP versus SHP-2 in B cells. 
  Page 109 - 111Mikhalap SV, Shlapatska LM, Berdova GG, Yun TJ, Nichols KE, Clark EA, Sidorenko SPOxford University Press2002
• Encyclopedia of Molecular Medicine. 
  Chapter: Function of the T-cell co-stimulatory molecule, SLAM. 
  Page 2916 - 2919Tangye SG, Nichols, KEJohn Wiley & Sons, Inc., New York, NY2001
• Encyclopedia of Molecular Medicine. 
  Chapter: The X-linked lymphoproliferative disease gene, SH2D1A. 
  Page 2986 - 2989Nichols KE, Tangye SJohn Wiley & Sons, Inc., New York, NY2001
• Principles of Molecular Medicine. 
  Chapter: Molecular genetics of renal neoplasms: Wilms’ tumor and renal cell carcinoma. 
  Page 685 - 691Nichols KE, Haber DAHumana Press1998
• Join now to see all

Abstracts/Posters

• The Combination of Dexamethasone and Ruxolitinib Synergistically Attenuates Disease Manifestations in a Preclinical Model of Hemophagocytic Lymphohistiocytosis
  Kim E. Nichols, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Predictive Genomic Sequencing: The Impact of a Structured Informed Consent Model on Parental Understanding.
  Johnson LM, Valdez J, Nichols KE, Mandrell B, Baker J, Pediatric Academic Societies Meeting, 1/1/2017
• Dampened inflammation with ruxolitinib treatment leads to CD8+ T cell exhaustion and induction of T regulatory cells in a murine model of HLH.
  Albeituni S, Verbist K, Tedrick P, Tillman H, Nichols KE, American Association of Immunologist Annual Meeting, 1/1/2017
• Pediatric Malignant Neoplasms Involving Horseshoe Kidneys: An Institutional Experience Including The First Case of Clear Cell Sarcoma of Kidney and The First Reported ...
  Santiago T, Clay MR, Azzato EM, Newman S, Fernandez-Pineda I, Nichols KE, Zhang J, Downing JR, Davidoff AM, Brennan RC, Ellison DW, United States and Canadian Academy of Pathology, 1/1/2017
• Analysis of Germline Variants of Uncertain Significance from Paired Tumor-Germline Samples in a Pediatric Genomic Sequencing Research Study.
  Kesserwan C, Hedges D, Newman S, Hamilton K, McGee R, Quinn E, Nuccio R, Valdez J, Foy S, Nakitandwe J, Harrison L, Ouma A, Hines-Dowell S, Shurtleff S, Azzato E, Elli..., Curating the Clinical Genome Meeting, 1/1/2017
• Considerations for Genetic Counseling of Adult Survivors of Childhood Cancer.
  Lewis CP, Nichols KE, 15th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer, 1/1/2017
• Enhancing the Anti-Leukemia Functions of Invariant Natural Killer T Cells Using a Tumor Antigen-Specific Model.
  Gohl T, Guan P, Mack RM, Evans E, Zauderer M, Das R, Nichols KE, 16th annual CHI Peptalk, Bispecific antibody Therapeutics, 1/1/2017
• Germline mutations in cancer predisposition genes and risk for subsequent neoplasms among long-term survivors of childhood cancer in the St. Jude Lifetime Cohort.
  Wang Z, Wilson CL, Easton J, Hedges D, Liu Q, Wu G, Rusch M, Edmonson M, Levy S, Lanctot J, Caron E, Shelton K, Currie K, Lear M, Mulder H, Yergeau D, Rosencrance C, V..., American Association for Cancer Research Annual Meeting, 1/1/2017
• Unknown consanguinity reveals homozygous CLCN7 mutations previously reported with autosomal dominant osteopetrosis type II: a case report.
  Nuccio R, Hines-Dowell S, Boals M, McGee R, Quinn E, Reiss U, Nichols KE, 35th Annual Educ. Conf; Nat. Soc. of Genetic Counselors, Seattle, WA, 1/1/2016
• Parent-child communication and testing for cancer predisposition.
  Mandrell B, Valdez J, Gattuso J, Ogg S, Nichols KE, Association of Pediatric Hematology Oncology Nurses Annual Meeting, Providence, RI, 1/1/2016
• Hemophagocytic Lymphohistiocytosis (HLH) in Langerhans cell histiocytosis (LCH): A multicenter retrospective descriptional study.
  Chellapandian D, Zhang R, Jeng M, van den Bos C, Santa-María López V, Lehmberg K, Sieni E, Wang Y, Nakano T, Williams J, Fustino N, Astigarraga I, Dunkel I, An Q, Chen..., American Society of Hematology Annual Meeting, San Diego, CA, 1/1/2016
• Germline Genetic Variation in IKZF1 and Predisposition to Childhood Acute Lymphoblastic Leukemia.
  Churchman ML, Qian M, Zhang R, te Kronnie G, Yang W, Hui Z, Lana T, Tedrick P, Baskin R, Devidas M, Raetz E, Larsen E, Martin PL, Bowman WP, Winick N, Mardis E, Fulton..., American Society of Hematology Annual Meeting, San Diego, CA, 1/1/2016
• Comprehensive Functional Characterization of Germline ETV6 Variants Associated with Inherited Predisposition to Acute Lymphoblastic Leukemia in Children.
  Nishii R, Baskin R, Moriyama T, Hoshitsukid K, Metzger ML, Wu G, Devidas M, Yang W, Tedrick P, Quinn E, Gastier-Foster JM, Raetz E, Larsen E, Martin PL, Bowman WP, Win..., American Society of Hematology Annual Meeting, San Diego, CA, 1/1/2016
• A combination of ATG and Etoposide for the treatment of HLH: Results of the HIT-HLH trial.
  Jordan MB, Henry M, Allen CE, McClain K, Greenberg J, Ladisch S, Hermiston ML, Jeng M, Degar BA, Kanter J, Naqvi A, Joyce M, Nichols KE, Teachey DT, Marsh RA, Grimley ..., 32nd Annual Meeting of the Histiocyte Society, Dublin, Ireland, 1/1/2016
• Hemophagocytic Lymphohistiocytosis (HLH) in Langerhans cell histiocytosis (LCH): A multicenter retrospective descriptional study.
  Chellapandian D, Zhang R, Jeng M, van den Bos C, Santa Maria A, Lehmberg K, Sieni E, Wang Y, Nakano TA, Williams J, Fustino NJ, Astigarraga I, Dunkel IJ, An QA, Cheng ..., 32nd Annual Meeting of the Histiocyte Society, Dublin, Ireland, 1/1/2016
• Clinician knowledge and utilization of genome sequencing results.
  Mandrell B, Johnson L, Valdez J, Hines-Dowell S, Nichols KE, International Society of Nurses in Genetics Annual Meeting, Dublin, Ireland, 1/1/2016
• Genomes for Kids (G4K): A feasibility study using Whole exome (WES), Whole genome (WGS) and RNA sequencing on tumor and germline samples.
  Hines-Dowell S, Ouma A, Harrison L, Johnson L, Kubal M, Mandrell B, Kesserwan C, Zhang J, Downing JR, Nichols KE, International Society of Nurses in Genetics Annual Meeting, Dublin, Ireland, 1/1/2016
• Expanding the Phenotype of DICER1 Syndrome: Two Years of DICER1 Testing in a Pediatric Cancer Genetics Clinic.
  McGee R, QuinnE, Nuccio R, Hines-Dowell S, Kesserwan C, Nichols KE, 35th Annual Educ. Conf; Nat. Soc. of Genetic Counselors, Seattle, WA, 1/1/2016
• Assessing clinician confidence and preferences when incorporating genomics in the pediatric oncology clinic: Insights from an institutional survey.
  Quinn E, Johnson L-M, Valdez JM, McGee RB, Nuccio R, Hines-Dowell S, Kesserwan C, Mandrell BN, Nichols KE, 35th Annual Educ. Conf; Nat. Soc. of Genetic Counselors, Seattle, WA, 1/1/2016
• Mosaic Monosomy 7: A New Syndrome with Increased Risk of Hematologic Disease.
  Akgumus GT, Fan J, Wertheim GB, Mulchandani S, Nichols KE, Wilmoth DM, Gleason AG, Zackai EH, Biegel JA, Spinner NB, Li M, Conlin LK, Deardorff MA, Luo M, America College of Medical Genetics Annual Meeting, Tampa, FL, 1/1/2016
• Preemptive Clinical Pharmacogenetic Testing in Children: Patient and Parent Preferences.
  Ring S, Haidar CE, Kornegay N, Hoffman JM, Broeckel U, Evans WE, Nichols KE, Relling MV, Crews KR, American Society of Human Genetics, Vancouver, Canada, 1/1/2016
• Clinical utilization of whole-genome, whole exome and transcriptome sequencing integrative analysis for pediatric oncology molecular diagnostics.
  Azzato EM, Shurtleff SA, Nakitandwe J, Rusch M, Hedges D, Newman S, Zhang Z, Edmonson M, Thrasher A, Becksfort JB, Kesserwan C, Raimondi S, Nichols KE, Ellison DW, Z..., Association for Molecular Pathology, 1/1/2016
• Change in expert consensus based on availability of additional laboratory data over the course of MAS.
  Davì S, Minoia F, Martini A, Ruperto N, Ravelli A, Horne AC, Henter JI, Wulffraat NM, Wouters C, Wallace C, Uziel Y, Sterba G, Schneider R, Russo R, Ramanan AV, Pachlo..., 23rd European Paediatric Rheumatology Congress, 1/1/2016
• North American Consortium for Histiocytosis (NACHO) providing a mechanism to enhance clinical and translational research in Langerhans cell Histiocytosis.
  Rodriguez Galindo C, Abla O, Arceci R, Campbell P, Degar B, Filipovich A, Greenberg J, Hermiston M, Hogarty M, Jacobsen E, Jordan M, Jubran R, Ladisch S, McClain K, Me..., Hisiocyte Society Annual Meeting, Athens, Greece, 1/1/2015
• Managing uncertainty: Lessons learned from utilizing a biallelic MSH6 VUS to alter clinical care.
  Quinn E, McGee RB, Pappo AS, Broniscer A, Nichols KE, 34th Annual Education Conference of the National Society of Genetic Counselors, Pittsburgh, PA, 1/1/2015
• Join now to see all

Lectures

• Therapeutic Candidate Alpn-101, a Dual ICOS/CD28 Antagonist, Potently Suppresses Human/NSG Mouse Xenograft Graft Vs. Host Disease (GvHD) in a Dose Ranging Study and Re... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Pediatric Leukemia Predisposition Syndromes 
  60th American Society of Hematology Annual Meeting - 12/1/2018
• Inherited Hematopoietic Malignancies 
  60th American Society of Hematology Annual Meeting - 11/30/2018
• Childhood Cancer Predisposition: At the Tip of the Iceberg 
  Dana Farber Cancer Institute, Boston, MA - 1/17/2017
• Recommendations for Surveillance for Leukemia Predisposing Conditions 
  Washington, DC - 1/2/2017
• Targeting Jak-STAT Pathway in MAS and HLH 
  Mandarin Oriental, Washington, DC - 1/23/2016
• Pre-clinical studies of JAK inhibition in HLH 
  St. Jude Children’s Research Hospital, Memphis, TN - 1/21/2016
• Genes that predispose to pediatric cancer 
  Rio de Janeiro, Brazil - 1/18/2016
• Bioethical aspects of genomic studies 
  Rio de Janeiro, Brazil - 1/18/2016
• Meet the Expert: HLH and MAS 
  Dublin, Ireland - 1/17/2016
• Looking back and to the future; Janus kinase inhibition as a novel therapy for hemophagocytic lymphohistiocytosis 
  Dublin, Ireland - 1/17/2016
• Hereditary Syndromes associated with leukemia predisposition 
  Boston, MA - 1/8/2016
• Evaluation and management of cancer predisposition syndromes 
  Singapore - 1/4/2016
• Germline genetic testing in the pediatric oncology clinic: who, what and when? 
  Chicago, IL - 1/4/2016
• Introduction to cancer susceptibility syndromes that predispose to leukemia 
  San Diego, CA - 1/3/2016
• HLH genetics: what every family needs to know 
  Cincinnati, OH - 1/1/2016
• Update on the biology and treatment of X-linked lymphoproliferative syndrome, type 1/SAP deficiency 
  Cincinnati, OH - 1/1/2016
• New insights into the diagnosis and management of EBV-HLH 
  Athens, Greece - 1/29/2015
• Inhibition of diacylglycerol kinase alpha restores sensitivity to TCR-induced cell death and lessens immunopathology in a murine model of X-linked lymphoproliferative ... 
  Athens, Greece - 1/28/2015
• Clinical applications of Cancer Genomic Testing 
  San Diego, CA - 1/27/2015
• Translational studies in anti-tumor immunity and hyper-inflammation 
  St. Jude Children’s Research Hospital, Memphis, TN - 1/26/2015
• HLH Genetics: what does it mean for my family? 
  Cincinnati, OH - 1/19/2015
• Genetic testing and exome sequencing: their roles in the diagnosis of HLH 
  Cincinnati, OH - 1/19/2015
• SAP deficiency: Update on diagnosis, pathogenesis and management 
  Cincinnati, OH - 1/19/2015
• Interruption of signal transduction in the treatment of HLH 
  St. Jude Children’s Research Hospital, Memphis, TN - 1/8/2015
• Join now to see all

Other

• Li-Fraumeni Syndrome. GeneReviews at GeneTests: Medical Genetics Information Resource [database online]. 
  Schneider K, Zelley K, Nichols KE, Garber J
  http://www.genetests.org
  University of Washington, Seattle, WA - 1/1/2013
• 13th annual Nikolas Symposium - Langerhans cell histiocytosis (LCH): neoplasia or immune dysregulation? 
  Nichols K, Symposium Proceedings
  http://nikolas.info/index.html
  1/1/2003
• 12th annual Nikolas Symposium - Dendritic cell differentiation: signals, signaling and functional consequences as clues to possible therapy. 
  Nichols KE, Egeler RM, Perry VH, Arceci RJ, Symposium Proceedings
  http://nikolas.info/index.html
  1/1/2002
• 11th annual Nikolas Symposium – Cytokine networks in acute and chronic inflammation. 
  Nichols K, Symposium Proceedings
  http://nikolas.info/index.html
  1/1/2001
• AMSTERDAM 2000: A Joint Meeting of the Histiocyte Society and Nikolas Symposium. 
  Nichols K, Symposium Proceedings
  http://nikolas.info/index.html
  1/1/2000
• 10th annual Nikolas Symposium – Inflammation and the central nervous system. 
  Nichols K, Symposium Proceedings
  http://nikolas.info/index.html
  1/1/1999
• Bi-allelic mismatch repair deficiency syndrome. 
  Just M, McGee R, Quinn E, Nuccio R, Hines-Dowell S, Nichols KE
  http://www.stjude.org/stjude/v/index.jsp?vgnextoid=c90c5779a610d410VgnVCM100000290115acRCRD&cpsextcurrchannel=1
• Rhabdoid tumor predisposition syndrome. 
  Wiley S, Zelley K, Nichols KE
  http://www.chop.edu/service/oncology/our-programs/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/rhabdoid-predisposition-syndrome.html
• Noonan syndrome. 
  Brown H, Zelley K, Nichols KE
  http://www.chop.edu/service/oncology/our-programs/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/noonan-syndrome.html
• Pleuropulmonary blastoma family tumor and dysplasia syndrome (DICER1 syndrome). 
  Wiley S, Zelley K, Nichols KE
  http://www.chop.edu/service/oncology/our-programs/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/dicer1-syndrome.html
• Retinoblastoma. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/oncology/cancers-explained/retinoblastoma-diagnosing-and-treating-retinoblastoma-in-children.html
• X-linked lymphoproliferative syndrome. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/x-linked-lymphoproliferative-syndrome.html
• Wilms tumor related syndromes. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/wt1-related-wilms-tumor-wt-syndromes.html
• Von Hippel-Lindau syndrome. 
  K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/von-hippel-lindau-syndrome.html
• PTEN hamartoma tumor syndrome. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/pten-hamartoma-tumor-syndrome.html
• Peutz-jeghers syndrome. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/peutz-jeghers-syndrome-pjs.html
• Nevoid basal cell carcinoma syndrome. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/nevoid-basal-cell-carcinoma-syndrome.html
• Neurofibromatosis, Type 2. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/neurofibromatosis-type-1.html
• Neurofibromatosis, Type 1. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/neurofibromatosis-type-1.html
• Multiple endocrine neoplasia syndrome, Type 2. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/multiple-endocrine-neoplasia-type-2.html
• Multiple endocrine neoplasia, Type 1. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/multiple-endocrine-neoplasia-type-1.html
• Li Fraumeni syndrome. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/li-fraumeni-syndrome.html
• Juvenile polyposis syndrome. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/juvenile-polyposis.html
• Hereditary paraganglioma pheochromocytoma syndrome. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/hereditary-paraganglioma-pheochromocytoma-syndrome.html
• Hereditary Neuroblastoma. 
  Zelley K, Nichols KE
  http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/hereditary-neuroblastoma.html
• Join now to see all