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Office
660 S Euclid Ave
Saint Louis, MO 63110Phone+1 314-362-3500Fax+1 314-362-8015
Education & Training
- University of ChicagoFellowship, Endocrinology, Diabetes, and Metabolism, 1978 - 1980
- Michael Reese Hospital and Medical CenterResidency, Internal Medicine, 1977 - 1978
- Loyola University Medical CenterResidency, Internal Medicine, 1976 - 1976
- University of the WitwatersrandClass of 1973
Certifications & Licensure
- IL State Medical License 1977 - 2023
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Elected Member Institute of Medicine, 2006
- Fellow (FACP) American College of Physicians, 2003
Clinical Trials
- A Clinical Trial of Ginseng in Diabetes Start of enrollment: 2003 Sep 01
- Regulation of Hepatic Insulin Extraction Start of enrollment: 2000 Oct 01
- Islet Function and Clinical Analyses of Transplant Recipients Start of enrollment: 2000 Oct 01
Publications & Presentations
PubMed
- 282 citationsIncreased islet apoptosis in Pdx1+/- miceJames D. Johnson, Noreen Ahmed, Dan S. Luciani, Zhiqiang Han, Hung Tran
The Journal of Clinical Investigation. 2003-04-15 - 429 citationsRole of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.Anthony Pick, Joshua Clark, Christian Kubstrup, Matteo G. Levisetti, W. Pugh
Diabetes. 1998-03-01 - 101 citationsEffects of Aging on Insulin SecretionBarry Gumbiner, Kenneth S. Polonsky, William F Beltz, Penny Wallace, Ginger Brechtel
Diabetes. 1989-12-01
Press Mentions
- UChicago Medicine Breaks Ground on $121M Multispecialty Care Facility in Crown Point, IndianaAugust 5th, 2022
- Looking Back at the Advances During Dean Kenneth S. Polonsky's 12-Year TenureJuly 22nd, 2022
- Violent Crime ‘The Top Health Concern’ for Surveyed South Siders, UChicago Study FindsJuly 15th, 2022
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Grant Support
- Regulation Of Hepatic Insulin ExtractionNational Institute Of Diabetes And Digestive And Kidney Diseases1992–2011
- CTSA Infrastructure For Pediatric ResearchNational Center For Research Resources2008–2010
- CTSA Infrastructure For Clinical TrialsNational Center For Research Resources2008–2010
- CTSA Infrastructure For AIDS ResearchNational Center For Research Resources2008–2010
- Washington University Institute Of Clinical And Translational SciencesNational Center For Research Resources2007–2010
- Regulation Of Hepatic Insulin ExtractionNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2010
- A Proof-Of-Concept Clinical Trial Of Xenin-25 In The Treatment Of Type 2 DiabetesNational Institute Of Diabetes And Digestive And Kidney Diseases2009
- Washington University Institute Of Clinical And Translational Sciences (KL2)National Center For Research Resources2008–2009
- Washington University Institute Of Clinical And Translational Sciences (UL1)National Center For Research Resources2007–2009
- Washington University Institute Of Clinical And Translational Sciences (TL1)National Center For Research Resources2007–2009
- Washington University Institute Of Clinical And Translational SciencesNational Center For Research Resources2007
- Washington University Institute CTSA For Pediatric ResearchNational Center For Research Resources2007
- Washington University Institute CTSA For Clinical TrialsNational Center For Research Resources2007
- Washington University Institute CTSA For AIDS ResearchNational Center For Research Resources2007
- Regulation Of Hepatic Insulin ExtractionNational Center For Research Resources2004–2007
- Islet Transplantation In Type 1 Diabetic Patients Using The Edmonton ProtocolNational Center For Research Resources2004–2007
- Islet Function &Clinical Analyses Of Transplant RecipientsNational Center For Research Resources2004–2007
- A Clinical Trial Of Ginseng For Glucose ToleranceNational Center For Research Resources2005–2006
- Interdisciplinary Research Careers In Women'S HealthEunice Kennedy Shriver National Institute Of Child Health &Human Development2000–2006
- Regulation Of Hepatic Insulin ExtractionNational Center For Research Resources2004–2005
- A Clinical Trial Of Ginseng For Glucose IntoleranceNational Center For Complementary &Alternative Medicine2004–2005
- Regulation Of Hepatic Insulin ExtractionNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2005
- Proinsulin &Conversion Products To Insulinlike Immunoreactivity In IGT And NIDDMNational Center For Research Resources2000–2002
- Plasma Leptin Levels Indicate Energy BalanceNational Center For Research Resources2000–2002
- Is The Pancreatic Beta Cell Target Of Insulin Action In VivoNational Center For Research Resources2000–2002
- Altered Insulin Secretion In PTS W Genetic Forms Of NidNational Center For Research Resources2000–2002
- Troglitazone In Early Type 2 Diabetes MellitusNational Center For Research Resources1999–2002
- Pathobiology Of Beta Cell Dysfunction And Apoptosis In Diabetes MellitusNational Institute Of Diabetes And Digestive And Kidney Diseases1997–2002
- Insulin Secretion In Pancreas Transplant RecipientsNational Center For Research Resources1997–2002
- Effect Of Elevated FFA On Insulin SecretionNational Center For Research Resources1997–2002
- Beta Cell Function In Subjects With Impaired Glucose ToleranceNational Center For Research Resources1996–2002
- Pilot And Feasibility StudiesNational Institute Of Diabetes And Digestive And Kidney Diseases1993–2002
- Core--Radioimmunoassay And Clinical Studies LaboratoryNational Institute Of Diabetes And Digestive And Kidney Diseases1993–2002
- Regulation Of Hepatic Insulin ExtractionNational Institute Of Diabetes And Digestive And Kidney Diseases1997–2000
- Core--Radioimmunoassay LaboratoryNational Institute Of Diabetes And Digestive And Kidney Diseases1996–2000
- Beta Cell Function After Insulin InhibitionNational Center For Research Resources1997–1999
- Molecular Mechanisms/Beta Cell Dysfunction In DiabetesNational Institute Of Diabetes And Digestive And Kidney Diseases1994–1999
- Diabetes Research And Training CenterNational Institute Of Diabetes And Digestive And Kidney Diseases1992–1999
- Diabetes Prevention ProgramNational Institute Of Diabetes And Digestive And Kidney Diseases1996–1998
- Integrated Clinical And Basic Endocrinology ResearchNational Institute Of Diabetes And Digestive And Kidney Diseases1988–1998
- Dose Response Study Of TroglitazoneNational Center For Research Resources1997
- Exercise Training In Men And Women With Noninsulin Dependent Diabetes MellitusNational Center For Research Resources1995–1997
- Study Of Troglitazone In Patients With NIDDMNational Center For Research Resources1996
- Proinsulin &Insulin In IGT And NIDDMNational Center For Research Resources1996
- Patterns &Natural History Of Insulin Secretion In Kidney/Pancreas TransplantsNational Center For Research Resources1996
- Molecular Physiology Of Insulin Secretion And Its Pathophysiology In DiabetesNational Institute Of Diabetes And Digestive And Kidney Diseases1992–1996
- Insulin Secretion And Clearance--Normals And Patients With Insulin ResistanceNational Center For Research Resources1995
- NIDDM Primary Prevention Trial (Dpt-2)National Institute Of Diabetes And Digestive And Kidney Diseases1994–1995
- Insulin Secretion And ClearanceNational Center For Research Resources1993–1995
- Alterations Of Insulin Secretion In Genetic Forms Of NIDDMNational Center For Research Resources1993–1995
- Postprandial Lipoprotein Metabolism--Obesity, Diabetes, And Low HDL SubjectsNational Center For Research Resources1991–1995
- Diabetes Research And TrainingNational Institute Of Diabetes And Digestive And Kidney Diseases1994
- Intergrated Clinical And Basic Endocrinology ResearchNational Institute Of Diabetes And Digestive And Kidney Diseases1993–1994
- Diabetes Research And Training CentersNational Institute Of Diabetes And Digestive And Kidney Diseases1993
- Molecular Mechanisms Of Beta Cell Dyfunction In DiabetesNational Institute Of Diabetes And Digestive And Kidney Diseases1992–1993
- Insulin Secretion And Clearance In Normals And Patients With Insulin ResistanceNational Center For Research Resources1992–1993
- The Regulation Of Hepatic Insulin ExtractionNational Institute Of Diabetes And Digestive And Kidney Diseases1986–1993
- Threshold Of Adverse Effects Of Hypoglycemia On Cerebral FunctionNational Center For Research Resources1990–1991
- Insulin Secretion &Clearance In Normals &Pts. With Insulin ResistanceNational Center For Research Resources1990–1991
- Insulin Secretion In Nl And Obese Subjects And Patients W/Type II DiabetesNational Center For Research Resources1990
- The Effect Of Insulin Induced Hypoglycemia On Cortical FunctionNational Center For Research Resources1989
- Insulin Secretion In Nl And Obese Subjects And PTS. W/Type II DiabetesNational Center For Research Resources1989
- Tech. For Calculating Secretion &Post-Hepatic Delivery Of InsulinNational Center For Research Resources1988
- Insulin Secretion In Nl &Obese Subjects &Pts. W/Type II DiabetesNational Center For Research Resources1988
- Hyperinsulinemia And Hypoglycemia On Brain Glucose MetabolismNational Center For Research Resources1987–1988
- The Kinetics Of C-Peptide In Relation To InsulinNational Institute Of Diabetes And Digestive And Kidney Diseases1986–1988
- ?ANational Center For Research Resources1987
- Core--Radioimmunoassay And Clinical StudiesNational Institute Of Diabetes And Digestive And Kidney Diseases1986–1987
- Non-Invasive Methods For Calculating Secretion And Delivery Rates Of InsulinNational Center For Research Resources1985–1986
- Immunoreactivity Of Plasma SomatostatinNational Center For Research Resources1985–1986
- Hypoglycemia In Brittle, Insulin-Requiring DiabetesNational Center For Research Resources1985–1986
- Effects Of Changes In Blood Sugar On Cerebral FunctionsNational Center For Research Resources1985–1986
- Effect Of Insulin Induced Hypoglycemia On Cortical FunctionNational Center For Research Resources1985–1986
- The Regulation Of Hepatic Insulin ExtractionNat Inst Of Arthritis, Diabetes, Digestive &Kidney Diseases1985
- The Kinetics Of C-Peptide In Relation To InsulinNat Inst Of Arthritis, Diabetes, Digestive &Kidney Diseases1985
Professional Memberships
- Fellow
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