KennethBerMarguliesMD

PubMed

• Correction: Clinical studies in Myxomatous Mitral Valve Disease dogs: most prescribed ACEI inhibits ACE2 enzyme activity and ARB increases AngII pool in plasma.
  Smruti K Nair, Elliot V Hersh, Kenneth B Margulies, Henry Daniell
  Hypertension Research. 2025-02-14
• Unipolar Voltage Mapping to Predict Recovery of Left Ventricular Ejection Fraction in Patients With Recent-Onset Nonischemic Cardiomyopathy.
  Corentin Chaumont, Eliot G Peyster, Konstantinos C Siontis, Daniele Muser, Suraj Kapa
  Circulation. 2025-02-11
• Phosphorylation of CRYAB induces a condensatopathy to worsen post-myocardial infarction left ventricular remodeling.
  Moydul Islam, David R Rawnsley, Xiucui Ma, Walter Navid, Chen Zhao
  The Journal of Clinical Investigation. 2025-02-11

Journal Articles

• Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients with Heart Failure with Preserved Ejection Fraction  
  Gregory D Lewis, David J Whellan, Martin M LeWinter, Margaret M Redfield, Andrew L Smith, Eugene Braunwald, Michael M Givertz, Adrian F Hernandez, Sanjiv J Shah, Horng..., JAMA
• Suppression of Detyrosinated Microtubules Improves Cardiomyocyte Function in Human Heart Failure  
  Kenneth Margulies, MD, Nature

Abstracts/Posters

• A Novel Needleless Liquid Jet Injection System for Heart Failure Gene Therapy: Feasibility Study Demonstrates Enhanced Myocardial Distribution and Safety Profile in th...
  Fargnoli AS, Mu A, Katz MG, Williams RD, Dvorak J, Walling T, Margulies KB, Bridges CR, J Cardiac Fail, 1/1/2013
• A Novel Anti-Inflammatory Formulation Approach To Enhance Myocardial Gene Transfer: An In-Vitro Assessment of Aspirin Loaded Poly-Lactic Glycolic Acid Nanoparticles
  Fargnoli AS, Mu A, Katz MG, Williams, Sumaroka, MV, Levy R,Weiner, DB, Diamond SL, Margulies KB, Yang S, Bridges, CR, Mol Therapy, 1/1/2013
• Patients with Obesity and Type-2 Diabetes Present Cardiac IAPP Accumulation: A Source of Cardiomyocyte Ca2+ Dysregulation
  Despa S, Margulies KB, Bers D, Despa F, Circulation, 1/1/2011
• Active Myocardial TGF-beta Level is Significantly Increased in End-Stage Human Heart Failure
  Khan S, Jennifer J, Margulies, K, Tsuda T, Circulation, 1/1/2011
• Intrinsically Disordered Islet Amyloid Polypeptide Is a Pathogenic Link Between Type-2 diabetes and Heart Disease
  Despa S, Koch B, Margulies KB, Bers D, Despa F, Biophys J, 1/1/2011
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Lectures

• Takutsobo's Cardiomyopathy: Diagnosis and Recovery 
  2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
• Generation of 3D Myocardial Tissue from Stem Cells 
  11/17/2013
• Reverse Myocardial Remodeling Following LVAD: Where to We Stand? 
  1/13/2013
• Genomics and Transcriptional Profiling in Heart Failure 
  1/12/2013
• Changing Gene Expression w LVAD Support 
  9/1/2012
• Human Heart Tissue as a Platform for Translational Research 
  9/22/2011
• Cell Therapy and Cardiac Regeneration for Heart Failure: Where are we Now? 
  6/8/2011
• The Disconnect Between Cellular And Clinical Recovery: What Are We Missing? 
  4/15/2011
• MicroRNA During VAD Support 
  12/2/2010
• VADs as a Platform to Examine Myocardial Biology and Novel Therapeutics 
  2/16/2010
• Diastolic Heart Failure 
  12/12/2009
• VADs as a Platform to Understand Heart Failure Biology and Adjuvant Therapies 
  9/14/2009
• Transcriptional Profiling as a Mechanistic Discovery Platform 
  4/22/2009
• Sex-Based Differences in Contractile Reserve 
  11/9/2008
• Reverse Remodeling of the Heart: Phenomenology and Emerging Mechanistic Insights 
  1/7/2008
• Gene Expression Signatures in Human Heart Failure: Clinically Useful of Noise Discovery 
  11/4/2007
• State of the Art Lecture: Reverse Remodeling: Drugs, Genes, Proteins, Cells and the Heart. Does it Happen and is it Important? 
  10/19/2007
• Shear Stress Regulation of Endothelial Function in Heart Failure 
  4/16/2007
• Endogenous Cardiac Repair Potential in Human Hearts 
  3/17/2007
• Molecular Mechanisms of the Transition from Myocardial Hypertrophy to Failure 
  3/15/2007
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