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Office
310 Lafayette Ave Se
Ste 400
Grand Rapids, MI 49503Phone+1 616-752-6525Fax+1 616-752-6556
Education & Training
- University of MichiganFellowship, Gastroenterology, 1989 - 1992
- University of MichiganInternship, Internal Medicine, 1986 - 1987
- Washington University in St. Louis School of MedicineClass of 1986
Certifications & Licensure
- MI State Medical License 1991 - 2025
- American Board of Internal Medicine Internal Medicine
Publications & Presentations
PubMed
- 271 citationsMechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents : Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation b...Phyllissa Schmiedlin-Ren, David J. Edwards, Michael E. Fitzsimmons, Kan He, Kenneth S. Lown
Drug Metabolism and Disposition. 1997-11-01 - 265 citationsExpression of Enzymatically Active CYP3A4 by Caco-2 Cells Grown on Extracellular Matrix-Coated Permeable Supports in the Presence of 1α,25-Dihydroxyvitamin D3Phyllissa Schmiedlin-Ren, Kenneth E. Thummel, Jeannine M. Fisher, Mary F. Paine, Kenneth S. Lown
Molecular Pharmacology. 1997-05-01 - 452 citationsGrapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.Kenneth S. Lown, David G. Bailey, Robert J. Fontana, Srinivas K. Janardan, Constance H. Adair
The Journal of Clinical Investigation. 1997-05-15
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