KelvinDMacDonaldMD

Pediatric Pulmonology • Portland, OR

Cystic Fibrosis Pulmonology, Pediatric Asthma Pulmonology, Pediatric Bronchoscopy

Associate Professor, Associate CF Center Director.

Join to view full profile

Dr. MacDonald is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
Connect with colleagues in the same hospital or clinic.
Read the latest clinical news, personalized to your specialty.

See Dr. MacDonald's full profile

Already have an account?

Office
700 SW Campus Dr
Fl 7
Portland, OR 97239
Phone+1 503-346-0644

Summary

Dr. Kelvin MacDonald is a pediatric pulmonologist based in Portland, OR, with subspecialties in cystic fibrosis pulmonology, pediatric asthma pulmonology, and pediatric bronchoscopy. He completed his fellowship in pediatric pulmonology at Johns Hopkins University and a residency in pediatrics at Children's Hospital Medical Center of Akron. Dr. MacDonald is an Associate Professor at OHSU Doernbecher Children's Hospital and has experience in asthma, cystic fibrosis, and premature lung disease. He has co-authored several research publications and has been involved in clinical trials focused on pulmonary treatments. He has received multiple awards, including the Resident Award in Pulmonology from Akron Children’s Hospital and others that recognize his academic achievements.

Education & Training

Johns Hopkins UniversityFellowship, Pediatric Pulmonology, 2004 - 2008
Johns Hopkins UniversityCertificate, Epidemiology and Biostatistics, 2005
Children's Hospital Medical Center of Akron/NEOMEDResidency, Pediatrics, 2001 - 2004
American University of Integrative Sciences, Sint Maarten School of Medicine Class of 2001
Thomas Edison State UniversityB.S., 1994 - 1996
El Camino CollegeA.A., 1982

Certifications & Licensure

OR State Medical License 2013 - 2025
MD State Medical License 2004 - 2013
OH State Medical License 2001 - 2004
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Pulmonology

Awards, Honors, & Recognition

Resident Award: Intensive Care Unit and Pulmonology Akron Children’s Hospital, 2004
Clinical Achievement Award for Academic Honors University of Saint Eustatius, 2001
50 Most Distinguished Alumnus Award El Camino College 50th Anniversary, 1997

Clinical Trials

Testing the Effect of Adding Chronic Oral Azithromycin to Inhaled Tobramycin in People With Cystic Fibrosis (CF) Start of enrollment: 2016 Oct 21
Completed
Phase 4
Streamlined Treatment of Pulmonary Exacerbations in Pediatrics Pilot Study Start of enrollment: 2020 Nov 10
COMPLETED
NA

Publications & Presentations

PubMed

Pulmonary function tests in the neonatal intensive care unit and beyond: a clinical review.
Mitzi A Go, Kelvin D MacDonald, Manuel Durand, Cindy T McEvoy
Journal of Perinatology. 2025-02-28
Neonatal pulmonary function tests in infants born to COVID-19 positive mothers.
Katy Ruch, Kelvin D MacDonald, Kseniya Parkhotyuk, Diane Schilling, Mathew Olson
Journal of Perinatology. 2025-02-21
2 citations
Extended Continuous Positive Airway Pressure in Preterm Infants Increases Lung Growth at 6 Months: A Randomized Controlled Trial.
Cindy T McEvoy, Kelvin D MacDonald, Mitzi A Go, Kristin Milner, Julia Harris
American Journal of Respiratory and Critical Care Medicine. 2025-02-20

Journal Articles

Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway
Liang L, Macdonald K, Schwiebert EM, Zeitlin PL, Guggino WB, Am J Physiol Cell Physiol, 1/1/2009
Lubiprostone Activates non-CFTR dependent Respiratory Epithelial Chloride Secretion in Cystic Fibrosis Mice
Macdonald KD, McKenzie KR, Zeitlin PL, Am J Physiol Lung Cell Mol Physiol, 1/1/2008
Cystic Fibrosis Transmembrane Regulator [CFTR] Protein mutations “Class” Opportunity for Novel Drug Innovation
Macdonald KD, McKenzie KR, Zeitlin PL, Paediatr Drugs, 1/1/2007
Electrolyte Determination on Arterial Blood Gas Samples: More Tools for the RCP
MacDonald KD. Cockerham C, RT Journal, 1/1/1999
Applied Pulmonary Mechanics
MacDonald KD, Wirtschafter DD, Neo Inten Care, 1/1/1992
Just in Time: Infant Synchronous Ventilation
MacDonald KD, Wagner W, RT Journal, 1/1/1992
Pulmonary Mechanics Measurements Improve Neonatal Ventilation
MacDonald KD, RC Advance, 1/1/1992
Considerations when Using the Novametrix C/D Adaptor During HFOV Letter to the Editor
MacDonald KD, Wagner W, Resp Care, 1/1/1991
Pediatric PFT carts, is there a “Gold standard”? Letter to the Editor
MacDonald KD, Wang PB, Resp Care, 1/1/1989
Join now to see all

Books/Book Chapters

Respiratory Care Clinics of North America
Chapter: Volume and Pressure Controlled Ventilation in PICU
Page 607 - 618MacDonald KD, Johnson SEditors: Sayler J.WB Saunders1996
Neonatal Pulmonary Mechanics: A Casebook
Cventnic W, MacDonald, KDBicore Professional Publications1994
Year Book of Neonatal and Perinatal Medicine
Chapter: Computerized Pulse Oximetry and Pulmonary Mechanics in Intubated Low birth Weight Infants with Acute and Chronic Lung Disease (CLD)
Page 246 - 248Durand M, McEvoy C, MacDonald KEditors: Klaus MH, Fanaroff AA.Mosby, Baltimore, MD1993

Abstracts/Posters

Cigarette Smoke Extract Induces A Rapid, Voltage-Dependent Block of CFTR
MacDonald KD, Moran AR, Norimatsu Y, Dawson DC, Am. J. Respir. Crit. Care Med., 1/1/2013
So You Think You Can Dance: Pilot Testing Of Exergaming With Youth In The Inpatient Setting
Wilson AC, Cusick J, Klein, B, MacDonald, KD, Pediatric Pulm, 1/1/2016
Maternal Obesity Before Pregnancy Is Associated With Increased Steroid Prescriptions In Early Childhood
MacDonald KD, Vesco K, Nguyen T, Funk K , Donovan J, Webster J, Stevens V, McEvoy CR, Am. J. Respir. Crit. Care Med., 1/1/2015
High-Fat Diet Before And During Pregnancy Increases Airway Hyperreactivity In Offspring
MacDonald KD, Moran AR, Plateau A, McEvoy CR, Am. J. Respir. Crit. Care Med., 1/1/2015
Vancomycin and Tobramycin Concomitant Therapy Does Not Lead to Reduction in GFR Compared To Monotherapy in CF Patients
Muirhead C, Lim JY, Lapidus JA, MacDonald KD, Pediatr. Pulmonol., 1/1/2014
Aerosol Delivery Of Methacholine During Oral Intubated Measurement Of Murine Lung Mechanics
MacDonald KD, McEvoy C, Minor NC, Scott GD, Am. J. Respir. Crit. Care Med., 1/1/2012
Nasal Potential Difference (NPD) Is A Useful Diagnostic Modality For Individuals With Some Features Of Classic CF And Non-diagnostic Sweat Electrolytes or CFTR Mutatio...
Callahan KA, Sturner RA, Walker DM, Curtin-Brosnan J, MacDonald KD, Zeitlin PL, Pediatr. Pulmonol., 1/1/2012
Acute inhibition of CFTR by aqueous components of cigarette smoke and rescue by PG-01, a CFTR potentiator
MacDonald KD, Moran AR, Dawson DC, National Institute of Child Health and Human Development (NICHD) Child Health Research Centers Annual Meeting, Santa Monica, CA, 1/1/2012
Increased Pregravid Body Mass Index Is Associated With Subsequent Bronchodilator Prescriptions In Early Childhood
MacDonald KD, Vesco K, Nguyen T, Funk K, Stevens V, McEvoy C, Am. J. Respir. Crit. Care Med., 1/1/2012
Excessive Gestational Weight Gain in Women with a Normal Pregravid Body Mass Index is Associated with Increased Bronchodilator Prescriptions in Early Childhood
McEvoy C, MacDonald KD, Vesco K, Nguyen T, Funk K, Donovan J, V Stevens V, PAS Annual Meeting, 1/1/2012
Lubiprostone activates CFTR via EP4, not ClC-2
MacDonald KD, Norimatsu Y, Moran AR, Dawson D, National Institute of Child Health and Human Development (NICHD) Child Health Research Centers Annual Meeting, Raleigh – Durham, NC, 1/1/2011
Pulmonary exacerbation scoring during telephone triage: a single center experience
MacDonald KD, McCullar BG, Kraynack NC, Pediatric Pulm, 1/1/2011
Butyrate derivatives increase short circuit current in F508del CFTR expressing Fisher Rat thyroid cells
MacDonald KD, Moran AR, Mason AK, Zeitlin PL, Pediatric Pulm, 1/1/2011
Patient factors associated with failure of oral antibiotic therapy in cystic fibrosis pulmonary exacerbation
MacDonald, KD, Briggs EC, Nguyen T, Wall MA, Pediatric Pulm, 1/1/2010
A Novel Oral Short Chain Fatty Acid Restores Chloride Transport In F508del Cystic Fibrosis Mice
MacDonald KD, Henderson M, Kamal M, Nguyen T, Perrine SP, Zeitlin PL, Am. J. Respir. Crit. Care Med., 1/1/2010
Cobiprostone induces CFTR dependent and independent currents in Calu-3 airway epithelial cells
MacDonald KD, Moran AR, Dawson D, National Institute of Child Health and Human Development (NICHD) Child Health Research Centers Annual Meeting, Philadelphia, PA, 1/1/2010
ClC-2 Expression Impacts Perinatal Survival in Cystic Fibrosis Knockout Mice.
Zeitlin PL, MacDonald KD, Vij N, Am. J. Respir. Crit. Care Med., 1/1/2008
MacDonald KD, Shin G, Flotte TR, Zeitlin PL, Fischer AC, Mol Ther, 1/1/2008
Zeitlin, P.L. Activation of nasal epithelial ClC-2 channels rescues chloride transport in cystic fibrosis mice
MacDonald KD, McKenzie KR, Vij N, Henderson MJ, Zeitlin PL, Pediatric Pulm, 1/1/2007
3H-Adenosine 5’-Monophosphate (3H-AMP) Lung Uptake as a Marker of Normal Pulmonary Function in a Mouse Model of LPS Induced Lung Inflammation
Cho S, MacDonald KD, Zeitlin PL, Wahl R, J Nucl Med, 1/1/2007
Lung Mechanics in Heterozygous CF Mice after Repeated LPS Dosing
MacDonald KD, McKenzie KR, Mitzner W, Zeitlin PL, Proceedings of the American Thoracic Society International Meeting, 1/1/2007
Enhanced ClC-2 Mediated Chloride Transport in K18rtTAhClC-2 Mouse Nasal Epithelia
MacDonald KD, Vij N, Zeitlin PL, North American Cystic Fibrosis Conference, 1/1/2006
Repeated Measure of Murine Lung Mechanics by End Inflation Occlusion
Macdonald KD, Mitzner W, Zeitlin PL, Proc of ATS, 1/1/2006
Functional Expression of hClC2 in a Transgenic Murine Model
Macdonald KD, Vij N, Zeitlin PL, Proc of ATS, 1/1/2006
Use of a Hot Wire Anemometer in the Differential Diagnosis of Neonatal Endotracheal Tube Obstruction
MacDonald KD, Wirtschafter DD, Franceschini R, McEvoy C, Resp Care, 1/1/1988
Join now to see all

Lectures

Maternal Obesity and Childhood Lung Health
Portland, OR - 1/1/2017
Maternal Obesity and Airway Hyperreactivity in the Offspring
Seattle, WA - 1/1/2015
Maternal Origins of Pediatric Asthma
Portland, OR - 1/1/2015
CFTR Modulators
1/1/2014
Cystic Fibrosis New and Updated Therapeutics
Portland, OR - 1/1/2011
Cystic Fibrosis Therapeutics Update
Portland, OR - 1/1/2011
Alternate chloride channels in Cystic Fibrosis
Seattle, WA - 1/1/2010
Otolaryngologic Manifestations of Cystic Fibrosis
1/1/2009
Primary snoring and growth failure in a patient with Cystic Fibrosis
1/1/2008
Home Respiratory Care
1/1/2008
Thirteen Month Old Premature Infant with Chronic Lung Disease and Snoring
1/1/2006
Synchronous Infant Ventilation and Pressure Support Ventilation in Children
Fukuoka, Japan - 1/1/1992
Join now to see all

Other

Contributor to Basic Science of Cystic Fibrosis and Living with CF: Medications
MacDonald KD, Johns Hopkins CF Information website
www.hopkinscf.org
1/1/2006