KathleenMaryHertzerMDPhD, FACS

PubMed

• 37 citations
  Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer.
  Kathleen M. Hertzer, Mu Xu, Aune Moro, David W. Dawson, Lin Du
  Pancreas. 2016-03-01
• 8 citations
  E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice
  Alexander P. Stark, Hui-Hua Chang, Xiaoman Jung, Aune Moro, Kathleen M. Hertzer
  Surgery. 2015-12-01
• 24 citations
  Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1.
  Hui-Hua Chang, Steven H. Young, James Sinnett-Smith, Caroline Ei Ne Chou, Aune Moro
  American Journal of Physiology. Cell Physiology. 2015-11-15

Journal Articles

• Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer  
  Hertzer, KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G, Pancreas, 1/1/2016
• E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice  
  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OK, Eibl G, Surgery, 1/1/2015
• Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+ mediated mechanism in the human pancreatic carcinoma cell line PANC-1  
  Chang GG, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G, Am J Physiol Cell Physiol, 1/1/2015
• High Fat, High Calorie Diet Promotes Early Pancreatic Neoplasia in the Conditional KrasG12D Mouse Model  
  Dawson D, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol S, Lugea A, Gukovskaya AS, Li G, Hines, OJ, Rozengurt E, Eibl G, Cancer Prev Res, 1/1/2013
• MR-143 decreases COX-2 mRNA stability and expression in pancreatic cancer cells  
  Pham H, Rodriguez CE, Donald GW, Hertzer KM, Jung XS, Chang HH, Moro A, Reber HA, Hines OJ, Eibl G, Biochem Biophys Res Commun, 1/1/2013
• Baicalein - an intriguing therapeutic phytochemical in pancreatic cancer  
  Donald, G, Hertzer, K, and G. Eibl, Current Drug Targets, 1/1/2012
• The interplay of the N- and C-terminal domains of MCAK control microtubule depolymerization activity and spindle assembly  
  Ems-McClung SC, Hertzer KM, Zhang X, Miller MW, Walczak CE, Mol Biol Cell, 1/1/2007
• Full Length Dimeric MCAK is a More Efficient Microtubule Depolymerase than Minimal Domain Monomeric MCAK  
  Hertzer KM, Ems-McClung SC, Kline-Smith SL, Lipkin TG, Gilbert SP, and CE Walczak, Mol Biol Cell, 1/1/2006
• Kin I kinesins: insights into the mechanism of depolymerization  
  Hertzer KM, Ems-McClung SC, and CE Walczak, Crit Rev Biochem Mol Biol, 1/1/2003
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Books/Book Chapters

• Operative Techniques in Surgery 
  Chapter: Laparoscopic Pancreatic Debridement 
  Hertzer KM, OJ HinesEditors: Mulholland et. Al.Lippincott Williams & Wilkins, Philadelphia, PA2014

Abstracts/Posters

• A High Fat, High Calorie Diet Creates a Pro-Inflammatory Environment in the Pancreas and Peri-Pancreatic Fat during pancreatic cancer development in the KrasG12D Mouse...
  Hertzer KM, Academic Surgical Congress, 1/1/2014
• Diet-induced obesity leads to differential inflammation of adipose tissue depot and cytokine profile modifications in the KrasG12D mouse model.
  Hertzer, KM, A Moro, OJ Hines and G. Eibl, American Association for Cancer Research Special Conference on Pancreatic Cancer, 1/1/2014
• Diet-induced obesity leads to differential inflammation of adipose tissue depot and cytokine profile modifications in the KrasG12D mouse model.
  Hertzer, KM, A Moro, OJ Hines and G. Eibl, American Pancreatic Association Annual Meeting, 1/1/2014
• A High Fat, High Calorie Diet leads to inflammation of the pancreas and adipose tissue in the KrasG12D mouse model.
  Hertzer, KM, A. Moro, DW Dawson, OJ Hines, G. Eibl, American Pancreatic Association Annual Meeting, 1/1/2013
• Acceleration of Pancreatic Cancer Development in the Conditional KrasG12D Mouse Model by a High Fat, High Calorie Diet.
  Hertzer KM, Longmire Surgical Society Scientific Talks, 1/1/2013
• The Effect of a high Fat, High Calorie Diet on Peri-Pancreatic Inflammation on Pancreatic Cancer Development.
  Hertzer KM, American College of Surgeons Annual Meeting, 1/1/2013
• Structural Features of the Microtubule Important for MCAK Activity.
  Hertzer, KM and CE Walczak, Biophysical Society Annual Meeting, 1/1/2008
• Structural Features of the Microtubule Important for MCAK Activity.
  Hertzer, KM and CE Walczak, American Society for Cell Biology Annual Meeting, 1/1/2007
• Structural Features of the Microtubule Important for MCAK Activity.
  Hertzer, KM and CE Walczak, 14th American Cancer Society Great Lakes Cancer Symposium, 1/1/2006
• MCAK Domains Essential for Microtubule Depolymerization Activity During Spindle Assembly.
  Ems-McClung SC, Hertzer KM, Miller MW, and CE Walczak, 13th American Cancer Society Great Lakes Cancer Symposium and American Society for Cell Biology Annual Meeting, 1/1/2005
• The Role of Dimerization in the Catalytic Mechanism of xMCAK.
  Hertzer KM, Ems-McClung SC, and CE Walczak, American Society for Cell Biology Annual Meeting, 1/1/2003
• Exploring the Role of Dimerization in the Catalytic Mechanism of XKCM1.
  Hertzer KM, Ems-McClung SC, and CE Walczak, American Society for Cell Biology Annual Meeting, 1/1/2002
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Lectures

• Obesity, Inflammation and Pancreatic Cancer Development. 
  1/1/2013
• Structural Features of the Microtubule Important for MCAK Activity. 
  1/1/2006