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450 Brookline AveBoston, MA 02215
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Summary
- Kathleen Burns, M.D., Ph.D., joined Dana-Farber in 2020 as Chair of the Department of Pathology. She received her M.D. and Ph.D. degrees from Baylor College of Medicine, and was recruited to Johns Hopkins University School of Medicine for clinical pathology residency and hematopathology fellowship. Thereafter, she joined the faculty at Johns Hopkins, progressed through their academic ranks to Professor, and served as the pathology department's Deputy Director (Vice Chair) for Research and Director of the institution's Physician Scientist Training Program (PSTP). Dr. Burns's research focuses on high copy number genomic repeats and transposable elements, their contributions to human disease, and ways to leverage our understanding of their biology to treat cancers.
Her honors include the Richard Starr Ross Physician Scientist Award from Johns Hopkins University, a Career Award for Medical Scientists from the Burroughs Wellcome Fund, and membership in the American Society for Clinical Investigation. She has been invited as the Inaugural Thomas Wheeler Lecturer of Pathology, Baylor College of Medicine; the Daria Haust Lecturer of Pathology and Molecular Medicine, Queen’s University; and as the Scriver Family Visiting Professor in Genetic Medicine, McGill University.
Education & Training
- Johns Hopkins UniversityFellowship, Hematopathology, 2007 - 2008
- Johns Hopkins UniversityResidency, Pathology-Anatomic and Clinical, 2004 - 2007
- Baylor College of MedicineClass of 2004
Certifications & Licensure
- MA State Medical License 2020 - 2026
- MD State Medical License 2008 - 2020
- PA State Medical License 2007 - 2008
- American Board of Pathology Pathology - Clinical
- American Board of Pathology Hematopathology
Publications & Presentations
PubMed
- LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker.Pamela R de Santiago, Sho Sato, Stephanie J Zhang, Meaghan C Dougher, Kyle M Devins
NPJ Precision Oncology. 2025-03-06 - Comparative Genomics Reveals LINE-1 Recombination with Diverse RNAs.Cheuk-Ting Law, Kathleen H Burns
Biorxiv. 2025-02-03 - Recurrent oncogenic ZC3H18 mutations stabilize endogenous retroviral RNA.Tanzina Tanu, Anna M Cox, Jennifer Karlow, Priyanka Sharma, Xueyang He
Biorxiv. 2025-01-14
Press Mentions
- A Potential Danger of CRISPR Gene Editing and Why Base Editing May Be SaferJuly 14th, 2022
- 'Jumping Genes' Unusually Active in Many Gastrointestinal Cancers, Studies FindAugust 17th, 2015
- 'Jumping Genes' Unusually Active in Many Gastrointestinal Cancers, Studies FindAugust 17th, 2015
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Grant Support
- Immunological consequences of LINE-1 expression in cancerGEORGE WASHINGTON UNIVERSITY2024–2029
- Consequences of retrotransposition on genome integrityDANA-FARBER CANCER INST2023–2028
- Consequences of retrotransposition on genome integrityDANA-FARBER CANCER INST2023–2028
- Consequences of retrotransposition on genome integrityDANA-FARBER CANCER INST2023–2028
- Single Molecule Detection of L1 Insertions and IntermediatesDANA-FARBER CANCER INST2023–2025
- Characterizing the LINE-1 Retrotransposition-Replication ConflictDANA-FARBER CANCER INST2020–2025
- Characterizing the LINE-1 Retrotransposition-Replication ConflictDANA-FARBER CANCER INST2020–2025
- Characterizing the LINE-1 Retrotransposition-Replication ConflictDANA-FARBER CANCER INST2020–2025
- Investigating The Role Of Retrotransposons In Hematopoietic Neoplasias.National Cancer Institute2008–2011
External Links
- Johns Hopkins Physicianshttp://www.hopkinsmedicine.org/kathleen-burns
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