KatherineAHighMD
Pediatric Hematology & Oncology • Philadelphia, PAProfessor, Pediatrics, Perelman School of Medicine
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Office
3401 Civic Center Blvd
Children's Hospital Of Philadelphia - Hem/Onc
Philadelphia, PA 19104Phone+1 215-590-3535Fax+1 215-590-3992
Education & Training
Yale-New Haven Medical CenterFellowship, Hematology and Medical Oncology, 1981 - 1984
University of North Carolina HospitalsResidency, Internal Medicine, 1978 - 1981
University of North Carolina at Chapel Hill School of MedicineClass of 1978
Certifications & Licensure
PA State Medical License 1992 - 2024
NC State Medical License 1981 - 1998- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Hematology
Awards, Honors, & Recognition
- Elected Member Institute of Medicine, 2007
- Elected Member The American Society for Clinical Investigation, 1991
- Whos Who in Medicine and Healthcare Marquis Whos Who
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Publications & Presentations
PubMed
- 607 citationsImmune responses to AAV vectors: overcoming barriers to successful gene therapyFederico Mingozzi, Katherine A. High
Blood. 2013-07-04 - 100 citationsEffective gene therapy for haemophilic mice with pathogenic factor IX antibodiesDavid M. Markusic, Brad E. Hoffman, George Q. Perrin, Sushrusha Nayak, Xiaomei Wang
EMBO Molecular Medicine. 2013-11-01 - 132 citationsEngineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cellsAshley T. Martino, Etiena Basner-Tschakarjan, David M. Markusic, Jonathan D. Finn, Christian Hinderer
Blood. 2013-03-21
Abstracts/Posters
- Efficacy and Safety in 15 Hemophilia B Patients Treated with the AAV Gene Therapy Vector Fidanacogene Elaparvovec and Followed for at Least 1 YearKatherine A. High, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Lectures
- Hemostasis and Thrombosis Poster Walk for Trainees61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
- Activity of a FIX-Padua Transgene Product in Commonly Used FIX:C One-Stage and Chromogenic Assay Systems Following PF-06838435 (SPK-9001) Gene Delivery2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Biologic Therapeutics Seminar Series - Systems Approaches to Antibody-based Immunotherapy of CancerWashington University School of Medicine, Saint Louis, Missouri - 5/16/2012
Press Mentions
ACR Advocates for CPT Code ChangesSeptember 26th, 2024
AdvaMed Receives ANSI AccreditationSeptember 6th, 2024- AHN Completes Imaging Expansion at Allegheny Valley HospitalSeptember 5th, 2024
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Grant Support
- Gene Therapy For Hemophilia Using Muscle-Expressed FviiaNational Heart, Lung, And Blood Institute2011
- Administrative Core For Gene Therapy Of HemophiliaNational Heart, Lung, And Blood Institute2011
- Immune Responses To Capsid In Aav-Mediated Gene TransferNational Heart, Lung, And Blood Institute2010–2011
- Pediatric Hematology Research Training ProgramNational Heart, Lung, And Blood Institute2004–2011
- Gene Therapy For HemophiliaNational Heart, Lung, And Blood Institute2004–2011
- Clinical Trials Training SymposiumNational Heart, Lung, And Blood Institute2010
- Pathway To Accelerate Clinical Development In Gene Transfer: CGMP Vector CoreNational Center For Research Resources2010
- Safety &Efficacy Of Intravas. Del. Of Aav-F.Ix To Skeletal MuscleNational Heart, Lung, And Blood Institute2005–2009
- Immune Responses To AAV In Gene Transfer For HemophiliaNational Heart, Lung, And Blood Institute2005–2009
- Biological Roles Of Factors X And XANational Heart, Lung, And Blood Institute2004–2007
- Administrative CoreNational Heart, Lung, And Blood Institute2005
- Core A- Administrative CoreNational Heart, Lung, And Blood Institute2004
- AAV Mediated Muscle Directed Gene Therapy For Hemophilia BNational Heart, Lung, And Blood Institute2004
- Gene Therapy For HemophiliaNational Heart, Lung, And Blood Institute2000–2003
- Pediatric Hematology Research Training ProgramNational Heart, Lung, And Blood Institute1997–2003
- Gene Based Approach To Treating Hemophilic InhibitorsNational Heart, Lung, And Blood Institute2000–2002
- Core--TrainingNational Heart, Lung, And Blood Institute2000–2002
- AAV Mediated Muscle Directed Gene Therapy For Hemophilia BNational Heart, Lung, And Blood Institute2000–2002
- Inhibitor Formation In Gene Therapy For HemophiliaNational Heart, Lung, And Blood Institute1998–2001
- Gene Therapy Of Hemophilia B Using Hematopoietic Stem CellsNational Heart, Lung, And Blood Institute1996–2000
- Molecular Interactions Of Blood Coagulation Factor XANational Heart, Lung, And Blood Institute1996–1999
- Novel Stratagies For Gene Therapy Of Hemophilia BNational Heart, Lung, And Blood Institute1994–1998
- Regulation &Biosynthesis Of Vitamin K-Dependent FactorsNational Heart, Lung, And Blood Institute1992–1995
- Regulation &Biosynthesis Of Vitamin K-Dependent FactorsNational Heart, Lung, And Blood Institute1992
- Factor Ix--Molecular Defects &Regulation Of ExpressionNational Heart, Lung, And Blood Institute1988–1991
- Factor IX: Molecular Defects And Regulation Of ExpressiNational Heart, Lung, And Blood Institute1987
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