Karl D Kieburtz MD

Professor in the Departments of Neurology and Community and Preventative Medicine and is the Director of the Clinical Trials Coordination Center (CTCC) at the University of Rochester; Chair of the Parkinson’s Study Group (PSG) Executive Committee and Executive Committee member and Coordination Center Director for the Huntington Study Group (HSG)

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919 Westfall RdBldg C Suite 220Rochester, NY 14618
Phone+1 585-341-7500
Fax+1 585-341-7510

Education & Training

University of Rochester Medical CenterResidency, Neurology, 1986 - 1989
Highland Hospital of RochesterInternship, Transitional Year, 1985 - 1986
University of Rochester School of Medicine and DentistryClass of 1985

Certifications & Licensure

NY State Medical License 1985 - 2018
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2012-2014
585 Magazine Castle Connolly, 2012
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012
Whos Who in Medicine and Healthcare Marquis Whos Who
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Clinical Trials

National Institute of Neurological Disorders and Stroke (NINDS) Parkinson's Disease Neuroprotection Trial Start of enrollment: 2003 May 01
Completed
Phase 2
NINDS Parkinson's Disease Neuroprotection Trial of CoQ10 and GPI 1485 Start of enrollment: 2004 Jan 01
Completed
Phase 2
Safety and Tolerability Study of Phenylbutyrate in Huntington's Disease (PHEND-HD) Start of enrollment: 2005 Aug 01
Completed
Phase 2
Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease Start of enrollment: 2006 Oct 01
Completed
Phase 1, Phase 2
NET-PD LS-1 Creatine in Parkinson's Disease Start of enrollment: 2007 Mar 01
Terminated
Phase 3
A Study of the Novel Drug Dimebon in Patients With Huntington's Disease Start of enrollment: 2007 Jul 01
Completed
Phase 2
Coenzyme Q10 in Huntington's Disease (HD) Start of enrollment: 2008 Mar 01
Terminated
Phase 3
Bioavailability of Ubiquinol in Huntington Disease Start of enrollment: 2009 Sep 01
Completed
Phase 1
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression Start of enrollment: 2010 Jun 01
Completed
Phase 2
Pioglitazone in Early Parkinson's Disease Start of enrollment: 2011 Mar 01
Completed
Phase 2
Open-label Extension Study of Pridopidine (ACR16) in the Symptomatic Treatment of Huntington Disease Start of enrollment: 2011 Mar 24
Completed
Phase 2
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Publications & Presentations

PubMed

Predicting Cerebrospinal Fluid Alpha-Synuclein Seed Amplification Assay Status from Demographics and Clinical Data.
Charles S Venuto, Konnor Herbst, Lana M Chahine, Karl Kieburtz
Medrxiv. 2025-03-07
In Memoriam C. Warren Olanow (1941-2024).
Victor S C Fung, Kailash Bhatia, David J Burn, Christopher G Goetz, Mark Hallett
Movement Disorders. 2025-02-13
In Memoriam C. Warren Olanow (1941-2024).
Victor S C Fung, Kailash P Bhatia, David J Burn, Christopher G Goetz, Mark Hallett
Movement Disorders Clinical Practice. 2025-02-13

Press Mentions

Halting the Rise of Parkinson’sApril 24th, 2023
Common Dry Cleaning Chemical Linked to Parkinson’s DiseaseMarch 14th, 2023
CVN424 Shows Promise as Levodopa Add-on Therapy, Phase 2 Data ShowApril 6th, 2022
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Grant Support

Data Coordination And Biostatistics Center For The Nordic NetworkNational Eye Institute2009–2012
U.S. India Collaborative Partnership In Parkinson Disease (CPPD)National Institute Of Neurological Disorders And Stroke2011
Neuroprotection Studies In PD: A Coordinating CenterNational Institute Of Neurological Disorders And Stroke2001–2011
Midcareer Investigator Award--Patient Oriented ResearchNational Institute Of Neurological Disorders And Stroke1999–2003
Tolerability And Safety Study Of Lexipafant In HIV DementiaNational Center For Research Resources1998–2001
Selegiline Transdermal Sys In HIV Cognitive ImpairmentNational Center For Research Resources1998–2001
Amitriptyline And Mexilitine For Painful Neuropathy In HIV InfectionNational Institute Of Neurological Disorders And Stroke1997–2001
Treatment Of Persistent Weakness In Hypokalemic Paralysis With MinoxidilNational Center For Research Resources1997–2001
Neuropsychiatric Manifestations Of HIV Infection--Natural HistoryNational Center For Research Resources1996–2001
Coenzyme Q10 And Remacemide--Evaluation In HDNational Institute Of Neurological Disorders And Stroke1997–2000
Investigation Of CP-101,606 In Multisystem AtrophyNational Center For Research Resources1997
Protocol 161-101--Investigation Of CP-101,606 In Parkinson'S DiseaseNational Center For Research Resources1996–1997
Parallel Group, Placebo Controlled Efficacy Of OPC-14117 In HIV DementiaNational Center For Research Resources1996–1997
Parallel Group Study Of Thioctic Acid And Deprenyl In HIV DementiaNational Center For Research Resources1996–1997
Short Term Assessment Of Remacemide Tolerability In Huntingtons DiseaseNational Center For Research Resources1996
Amitriptyline And Mexilitine For Painful Neuropathy In HIV InfectionNational Institute Of Neurological Disorders And Stroke1994–1996
OPEN Trial Of DDI In Patients With AIDS Dementia ComplexNational Center For Research Resources1992