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Karl Insogna, MD, Endocrinology, New Haven, CT

KarlLInsognaMDmember ACP

Endocrinology • New Haven, CT

Diabetes, Lipid Metabolism, Osteoporosis & Bone Metabolism Medicine

Ensign Professor of Medicine, Yale School of Medicine

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  • Office

    789 Howard Ave
    Bldg
    New Haven, CT 06519
    Phone+1 203-737-1932
    Fax+1 203-737-2812

Summary

  • Dr. Karl Insogna is a tenured Professor at Yale and an internationally recognized expert in the field of metabolic bone disease. He has published widely on the topic in the field's leading scientific journals, is quoted often in the lay press, and has frequently appeared on radio and television. He is a Fellow of the American Association for the Advancement of Science, and was a member of the National Institutes of Health Consensus Conference, which established new recommendations for the optimal level of calcium intake for all Americans - now adopted nationwide. He is a leading researcher in the causes of bone loss in such diseases as osteoporosis and primary hyperparathyroidism, and is currently conducting studies in, among other areas, the role of diet in the development of osteoporosis.

    • Bone Center > Endocrinology & Metabolism | Internal Medicine | Yale School of Me

    Osteoporosis, a common bone disease, is an area of particular expertise at the Yale Bone Center. Measuring your bone density is recommended to determine your ri

Education & Training

  • Yale-New Haven Medical Center
    Yale-New Haven Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1980 - 1982
  • University of Rochester
    University of RochesterResidency, Internal Medicine, 1976 - 1980
  • Uconn School Of Medicine
    Uconn School Of MedicineClass of 1976

Certifications & Licensure

  • CT State Medical License
    CT State Medical License 1980 - 2025
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

  • CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2014
  • Elected Member The American Society for Clinical Investigation, 1994

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • A Randomized, Double‐Blind, Placebo‐Controlled, Phase 3 Trial Evaluating the Efficacy of Burosumab, an Anti‐FGF23 Antibody, in Adults with X‐Linked Hypophosphatemia: W...  
    Thomas Weber, Mary D Ruppe, Anthony A Portale, Erik A Imel, Thomas O Carpenter, Karl L Insogna, Farzana Perwad, Pisit Pitukcheewanont, Journal of Bone and Mineral Research

Press Mentions

  • Listen to "Peter Tebben Selected as Director of Yale Bone Center"
    Listen to "Peter Tebben Selected as Director of Yale Bone Center"October 7th, 2024
  • Discoveries & Impact (March 2023)
    Discoveries & Impact (March 2023)March 16th, 2023
  • Yale Bone Center Celebrates 35 Years of Consistent Progress
    Yale Bone Center Celebrates 35 Years of Consistent ProgressApril 14th, 2022
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Grant Support

  • The Role of Sphingosine Kinase in Bone AnabolismNIH2016–2020
  • Administrative CoreNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2012
  • Targeting Thrombospondin 1 In Bone ResorptionNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2011–2012
  • Core Center. Yale Core Center For Musculoskeletal DisordersNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2009–2012
  • AGRP Neurons Regulate Bone Remodeling In AgingNational Institute On Aging2011
  • Calcitonin For Treating X-Linked HypophosphatemiaNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2011
  • Role Of CSF-1 In Osteoclast FunctionNational Institute Of Dental &Craniofacial Research2001–2011
  • Role Of CSF-1 In Osteoclast FunctionNational Institute Of Dental &Craniofacial Research2010
  • Coloney Stimulating Factor 1 Regulation And Role In BoneNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2010
  • Impact Of A Protein Supplement On Bone Mass In Older WomenNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2006–2010
  • Conditional Deletion Of Pthrp In Articular ChondrocytesNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2007–2008
  • The Yale Core Center For Musculoskeletal DisordersNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004–2008
  • Microcomputed Tomography Device (Scanco Microct35)National Center For Research Resources2007
  • Role Of IL-6 In Pth-Induced Bone ResorptionNational Institute On Aging2002–2006
  • Colony Stimulating Factor 1 Regulation And Role In BoneNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2006
  • Evaluation Of Disorders Of Calcium MetabolismNational Center For Research Resources2005
  • Dietary Protein'S Effect On Gastric PHNational Center For Research Resources2005
  • Soy Protein And Calcium MetabolismNational Center For Research Resources2004–2005
  • Long Term Impact Of Protein On Calcium KineticsNational Center For Research Resources2004–2005
  • Impact On Dietary Protein On Bone-TurnoverNational Center For Research Resources2004–2005
  • Core A: Administrative Core, Pi., Karl InsognaNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004
  • Study To Evaluate Disorders Of CalciumNational Center For Research Resources2004
  • Effects Of Single Amino Acid Infusion On The CirculatingNational Center For Research Resources2004
  • Dietary Protein'S Effect Of Gastric PHNational Center For Research Resources2004
  • Yale Core Center For Musculoskeletal DisordersNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1999–2003
  • Role For IL6 In PTH Induced Bone ResorptionNational Institute On Aging1998–2001
  • Role Of Estrogen In Modulating PTH Induced Cytokine ReleaseNational Center For Research Resources1998–2001
  • Interleukin 6 As A Marker For Bone Loss In Primary HyperparathyroidismNational Center For Research Resources1998–2001
  • Impact Of Dietary Protein In Bone TurnoverNational Center For Research Resources1996–2001
  • Evaluation Of Human Calcium MetabolismNational Center For Research Resources1996–2001
  • Impact Of Dietary Protein On Calcium KineticsNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2000
  • CSF 1 And Osteoclast FunctionNational Institute Of Dental &Craniofacial Research1998–2000
  • Adjunctive 24,25 (OH) 2 Vitamin D3 Therapy In Familial Hyphosphatemic RicketsNational Center For Research Resources1997
  • Osteoblast And Pth/Pthrp Bone ResorptionNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1994–1997
  • Adjunctive 24,25 (OH) 2-Vitamin D3 Therapy In Familial Hyphosphatemic RicketsNational Center For Research Resources1996
  • Malignancy-Associated Pth-Like Peptide--Effect On BoneNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1989–1991

Professional Memberships

  • American Society for Bone and Mineral Research (ASBMR)
    Member
  • International Society for Clinical Densitometry
    Member
  • American College of Physicians - ACP
    Member
  • Endocrine Society - ENDO
    Member
  • National Osteoporosis Foundation
    Board of Trustees
  • Phi Beta Kappa, Phi Kappa Phi
    Member
  • American Federation for Medical Research
    Member
  • International Bone and Mineral Society
    Member
  • Connecticut Academy of Science and Engineering
    Member

External Links

Dr. Karl Insogna, Dr. Karl Insogna, MD, Dr. K Insogna, Dr. Karl L Insogna