Karen Hope Seal MD MPH
Professor of Medicine and Psychiatry, UCSF School of Medicine
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4150 Clement StSFVAHCS Box 116-ASan Francisco, CA 94121
Phone+1 415-221-4810
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Summary
- Dr. Karen Seal is a Professor of Medicine and Psychiatry at the University of California, San Francisco (UCSF). Based at the San Francisco VA Health Care System (SFVAHCS), she serves as Chief of the Integrative Health Service. In this capacity, she oversees interdisciplinary clinics including a post-9/11 Integrated Care Clinic for Iraq and Afghanistan veterans, the Integrated Pain Team Clinic, and the Integrative Health and Wellness Clinic as well as a Whole Health coaching program, yoga, Tai Chi, Battlefield Acupuncture and mind-body skills groups tailored to the needs of high-risk, high-needs veterans. As a health services researcher, she conducts randomized controlled trials and observational studies targeting mind-body problems common in veterans such as chronic pain, opioid dependence and posttraumatic stress disorder. Finally, Dr. Seal is dedicated to mentoring junior faculty to further establish evidence for complementary and integrative health for veterans and other underserved populations.
Education & Training
University of California (San Francisco)Residency, Internal Medicine, 1994 - 1997
Stanford University School of MedicineClass of 1994
Certifications & Licensure
CA State Medical License 1996 - 2026
Clinical Trials
- Motivational Interviewing to Engage Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans in Mental Health Treatment Start of enrollment: 2007 Sep 01
- GAME Veterans With PTSD Using Computer-Based Cognitive Training Start of enrollment: 2010 Apr 01
- Enhancing Cognitive Function and Reintegration in Iraq and Afghanistan Veterans With PTSD Using Computer-Based Cognitive Training Start of enrollment: 2012 Jun 01
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Publications & Presentations
PubMed
- 1 citationsBuprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids: A Randomized Clinical Trial.William C Becker, Karen H Seal, David B Nelson, Beth M DeRonne, Allyson M Kats
JAMA Internal Medicine. 2025-02-17 - 2 citationsCare Models to Improve Pain and Reduce Opioids Among Patients Prescribed Long-Term Opioid Therapy: The VOICE Randomized Clinical Trial.Erin E Krebs, William C Becker, David B Nelson, Beth M DeRonne, Agnes C Jensen
JAMA Internal Medicine. 2025-02-01 - Moral injury and mental health in healthcare workers are linked to organizational culture and modifiable workplace conditions: Results of a national, mixed-methods stu...Natalie Purcell, Daniel Bertenthal, Hajra Usman, Brandon J Griffin, Shira Maguen
PLOS Mental Health. 2024-12-23
Press Mentions
Editorial: Veterans Court a Good Start, but an Idea Worth Pursuing FurtherNovember 8th, 2017
Integrative Health Care and U.S. Military Personnel, Veterans, and Their FamiliesMarch 14th, 2017
Association of Mental Health Disorders with Prescription Opioids and High-Risk Opioid Use in US Veterans of Iraq and AfghanistanMarch 7th, 2012- Join now to see all
Grant Support
- Pain management teams using Whole Health to optimize function and safety in veterans: The TEAMWORK trialVA CONNECTICUT HEALTHCARE SYSTEM2024–2029
- Pain management teams using Whole Health to optimize function and safety in veterans: The TEAMWORK trialVA CONNECTICUT HEALTHCARE SYSTEM2024–2029
- Pain management teams using Whole Health to optimize function and safety in veterans: The TEAMWORK trialVA CONNECTICUT HEALTHCARE SYSTEM2024–2029
- Leveraging VA National Data, Expert Consensus, and Veteran Input to Develop and Refine a Pragmatic Trial Protocol Comparing Integrated Interventions to Address Co-Occurring Pain and PTSD in VeteransVETERANS AFFAIRS MED CTR SAN FRANCISCO2025–2026
- Leveraging VA National Data, Expert Consensus, and Veteran Input to Develop and Refine a Pragmatic Trial Protocol Comparing Integrated Interventions to Address Co-Occurring Pain and PTSD in VeteransVETERANS AFFAIRS MED CTR SAN FRANCISCO2025–2026
- Leveraging VA National Data, Expert Consensus, and Veteran Input to Develop and Refine a Pragmatic Trial Protocol Comparing Integrated Interventions to Address Co-Occurring Pain and PTSD in VeteransVETERANS AFFAIRS MED CTR SAN FRANCISCO2025–2026
- Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Function and Quality of Life in VeteransNORTHERN CALIFORNIA INSTITUTE/RES/EDU2024–2025
- Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Function and Quality of Life in VeteransNORTHERN CALIFORNIA INSTITUTE/RES/EDU2020–2025
- Neuropsychological Screening Of OEF/OIF Veterans In VA Primary CareVeterans Affairs2011
- Randomized Hepatitis B Vaccine Delivery Trial For IdusNational Institute On Drug Abuse2000
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