Karen G Louie MD

PubMed

• 4 citations
  Evaluation of In vitro drug screening leads using experimental models of human ovarian cancer
  Karen G. Louie, Thomas C. Hamilton, Robert H. Shoemaker, Robert C. Young, Robert F. Ozols
  Investigational New Drugs. 1992-07-01
• 424 citations
  Characterization of a cis-Diamminedichloroplatinum(II)-resistant Human Ovarian Cancer Cell Line and Its Use in Evaluation of Platinum Analogues
  Brent C. Behrens, Thomas C. Hamilton, Hidetaka Masuda, Karen R. Grotzinger, Jacqueline Whang-Peng
  Cancer Research. 1987-01-15
• 171 citations
  Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione.
  Robert F. Ozols, Karen G. Louie, Jacqueline Plowman, Brent C. Behrens, Robert L. Fine
  Biochemical Pharmacology. 1987-01-01

Journal Articles

• Immunocytochemical detection of tumor cells in bone marrow andp eripheral blood stem cell collections from patients with ovarian cancer  
  Ross, A.A., Miller, G.S., Moss, T.J., Kahn, D.G., Warren, N.E., Sweet, D.L., Louie, K.G., Schneiderman, E., Pecora, A.L., Meagher, R.C., Hertzig, R.H., Collins, R.H. a..., Bone Marrow Transplantation, 1/1/1995
• Evaluation of in vitro drug screening leads using experimental models of Human Ovarian Cancer  
  Louie, K.G., Hamilton, T.C., Shoemaker, R., Young, R.C., and Ozols, R.F., Invest. New Drugs, 1/1/1992
• Characterization of a cisplatin-resistant human ovarian cancer cell line and its use in evaluation of cisplatin analogues  
  Characterization of a cisplatin-resistant human ovarian cancer cell line and its use in evaluation of cisplatin analogues., Cancer Res, 1/1/1987
• Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor bearing nude mice by buthionine sulfoximine depletion of glutathione  
  Ozols, R.F., Louie, K.G., Plowman, J., Behrens, B.C., Fine, R.L., Dykes, D., and Hamilton, T.C., Biochem. Pharmacol., 1/1/1987
• Adriamycin accumulation and metabolism in adriamycin-sensitive and -resistant human ovarian cancer cell lines  
  Louie, K.G., Hamilton, T.C., Winker, M.A., Behrens, B.C., Klecker, R.W. Jr., Tsuruo, T., McKoy, W.M., Grotzinger, K.R., Young, R.C., and Ozols, R.F., Biochem. Pharmacol., 1/1/1986
• Serial Determinations of glutathione levels and glutathione related enzyme activities in human tumor cells in vitro  
  Batist, G., Behrens, B.C., Makuch, R., Hamilton, T.C., Katkl, A.G., Louie, K.G., Myers, C.E. and Ozols, R.F., Biochem. Pharmacol., 1/1/1986
• Long-term results of a cisplatin-containing combination chemotherapy regimen for the treatment of advanced ovarian cancer  
  Louie, K.G., Ozols, R.F., Myers, C.E., Ostchega, Y., Jenkins, J., Howser, D., and Young, R.C., J. Clin. Oncol., 1/1/1986
• Collateral susceptibility of adriamycin-, melphalan-, and cisplatin-resistant human ovarian tumor cells to bleomycin  
  Tsuruo, T., Hamilton, T.C., Louie, K.G., Behrens, B.C., Young, R.C., and Ozols, R.F., Jpn. J. Cancer Res. (Gann), 1/1/1986
• Activity of tricyclic nucleoside 5'-phosphate in in vitro and in vivo models of human ovarian cancer  
  Behrens, B.C., Hamilton, T.C., Louie, K.G., Grotzinger, K.R., McKoy, W.M., Tsuruo, T., and Ozols, R.F., Invest. New Drugs, 1/1/1986
• Preclinical evaluation of aclacinomycin A for the intraperitoneal treatment of human ovarian carcinoma  
  Louie, K.G., Hamilton, T.C., Behrens, B.C., Grotzinger, K.R., McKoy, W.M., Myers, C.E., Young, R.C., and Ozols, R.F., Cancer Chemother. Pharmacol., 1/1/1986
• Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine  
  Louie, K.G., Behrens, B.C., Kinsella, T.J., Hamilton, T.C., Grotzinger, K.R., McKoy, W.M., Winker, M.A., and Ozols, R.F., Cancer Res, 1/1/1985
• Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediate...  
  Hamilton, T.C., Winker, M.A., Louie, K.G., Batist, G., Behrens, B.C., Tsuruo, T., Grotzinger, K.R., McKoy, W.M., Young, R.C., and Ozols, R.F., Biochem. Pharmacol., 1/1/1985
• Induction of progesterone receptor with 17 -estradiol in human ovarian cancer  
  Hamilton, T.C., Behrens, B.C., Louie, K.G., and Ozols, R.F., J. Clin. Endocrinol. Metab., 1/1/1984
• Characterization of a xenograft model of human ovarian carcinoma which produces ascites an intraabdominal carcinomatosis  
  Hamilton, T.C., Young, R.C., Louie, K.G., Behrens, B.C., McKoy, W.M., Grotzinger, K.R., and Ozols, R.F., Cancer Res, 1/1/1984
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Books/Book Chapters

• Biochemical Modulators in Experimental and Clinical Studies 
  Chapter: Glutathione depletion with buthionine sulfoximine: Potential clinical applications. 
  Page 277 - 294Ozols, R.F., Hamilton, T.C., Louie, K.G., Behrens, B.C., and Young, R.C.Editors: F. Valeriote.Martinus Nijhoff1986

Abstracts/Posters

• Different rates of detection of breast cancer cells in peripheral blood stem cell (PBSC) collections in single versus multiple specimens.
  Ross, A.A., Cooper, B.W., Lazaris, H.M., Moss, T.J., Sweet, D.S., Winter, C.W., Louie, K.L., Madej, P.J., Schneiderman, E.C., Kohn, D.G., and Warner, N.E., Proceed. Amer. Soc. Clin. Oncol., 1/1/1994
• Autologous bone marrow transplantation for advanced breast cancer.
  Louie, K.G., Lonser, R.E., Madej, P.M., Winter, C.W., Schneiderman, E.S., and Sweet, D.L., Breast Cancer Research & Treatment, 1/1/1991
• Peripheral stem cell harvest rescue (PSTHR) for patients (PTS.) treated with high-dose chemotherapy and total body irradiation (TBI).
  Sweet, D., Lonser, R., Louie, K.G., and Madej, P., Proceed. Amer. Soc. Clin. Oncol., 1/1/1988
• Autologous bone marrow transplantation (ABMT) for refractory malignant disease: a community hospital experience.
  Sweet, D., Lonser, R., Madej, P., and Louie, K.G., Proceed. Amer. Soc. Clin. Oncol., 1/1/1988
• Buthionine sulfoximine reversal of x-ray cross resistance in drug-resistant human ovarian cancer cells.
  Louie, K.G., Behrens, B.C., Kinsella, T.J., Hamilton, T.C., Grotzinger, K.R., McKoy, W.M., Winker, M.A., Young, R.C., and Ozols, R.F., Proceed. Amer. Assoc. Cancer Res., 1/1/1985
• Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity by buthionine sulfoximine depletion of glutathione in drug resistant human ovarian cancer cell lines.
  Hamilton, T.C., Winker, M.A., Louie, K.G., Batist, G., Fine, R.L., Behrens, B.C., Tsuruo, T., Grotzinger, K.R., McKoy, W.M., Young, R.C., and Ozols, R.F., Proceed. Amer. Assoc. Cancer Res., 1/1/1985
• Cytotoxicity of 3 cisplatin analogues in a drug sensitive and a new cisplatin resistant human ovarian cancer cell line.
  Behrens, B.C., Grotzinger, K.R., Hamilton, T.C., Whang-Peng, J., Batist, G., Louie, K.G., Knutsen, T., Tsuruo, T., McKoy, W.M., Young, R.C., and Ozols, R.F., Proceed. Amer. Assoc. Cancer Res., 1/1/1985
• Resistance and cross resistance of human ovarian cancer cell lines to adriamycin, melphalan, and irradiation.
  Behrens, B.C., Louie, K.G., Hamilton, T.C., Curt, G., Kinsella, T., Young, R.C., and Ozols, R.F., Proceed. Amer. Assoc. Cancer Res., 1/1/1984
• A unique intraperitoneal model of human ovarian cancer.
  Hamilton, T.C., Young, R.C., Rogan, A.M., McKoy, W.M., Grotzinger, K.R., Behrens, B.C., Louie, K.G., and Ozols, R.F., Proceed. Amer. Assoc. Cancer Res., 1/1/1984
• Phase II study of intraperitoneal aclacinomycin with pharmacokinetics in patients with refractory ovarian cancer.
  Louie, K.G., Young, R.C., Myers, C.E., Ostchega, Y., and Ozols, R.F., N.C.I.M.B., 1/1/1984
• S. bovis endocarditis on a prosthetic heart valve, with a colonic neoplasm.
  Warren, J., Louie, K.G., Greenspahn, B.R., and Karunaratne, B., N. Engl. J. Med., 1/1/1981
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