Karen Hsiao Ashe MD
Professor, Department of Neurology at the University of Minnesota Founding Director, N. Bud Grossman Center for Memory Research and Care Edmund Wallace and Anne Marie Tulloch Chairs in Neurology and Neuroscience
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420 Delaware St SeMmc 295Minneapolis, MN 55455
Phone+1 612-626-0652
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Education & Training
Harvard Medical SchoolClass of 1982
Certifications & Licensure
MN State Medical License 1992 - 2022
American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- Elected Member Institute of Medicine, 2009
Publications & Presentations
PubMed
- Reengineering of Circularly Permuted Caspase-2 to Enhance Enzyme Stability and Enable Crystallographic Studies.Jessica L Fuller, Ke Shi, Steffen Pockes, Barry C Finzel, Karen H Ashe
ACS Chemical Biology. 2025-03-21 - Retraction Note: A specific amyloid-β protein assembly in the brain impairs memory.Sylvain Lesné, Ming Teng Koh, Linda Kotilinek, Rakez Kayed, Charles G Glabe
Nature. 2024-07-01 - Aβ∗56 is a stable oligomer that impairs memory function in mice.Peng Liu, Ian P Lapcinski, Chris J W Hlynialuk, Elizabeth L Steuer, Thomas J Loude Jr
Iscience. 2024-03-15
Press Mentions
University of Minnesota Researcher Tries to Back up Alzheimer’s Findings Amid Image ScandalJuly 31st, 2022- Was Alzheimer's Research Set Back by Doctored Information in a 'Groundbreaking' Study?July 25th, 2022
- Critical Elements of Leading Alzheimer’s Study Possibly FraudulentJuly 23rd, 2022
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Grant Support
- Prodrugs of potent and selective protease inhibitors as tauopathy therapeuticsMYRIEL, INC.2023–2025
- Mechanisms Of Memory Loss Caused By The Beta-Amyloid MoleculeNational Institute Of Neurological Disorders And Stroke2009–2011
- In Search Of The Molecular Basis Of Memory Loss In TauopathyNational Institute Of Neurological Disorders And Stroke2008–2011
- Specific Amyloid-Beta Oligomer AptamersNational Institute On Aging2009–2010
- The Biology Of Alzheimer'S Disease In Transgenic MiceNational Institute On Aging2004–2008
- The Beta-Amyloid Molecule In Learning And MemoryNational Institute Of Neurological Disorders And Stroke2004–2008
- Modulating Cognitive Function In TG2576 Mice Modeling ADNational Institute Of Mental Health2002–2006
- Biology Of Alzheimers Disease In Transgenic MiceNational Institute On Aging2000–2004
- Dissecting Pathogenic Domains Of APP In Transgenic MiceNational Institute Of Neurological Disorders And Stroke1999–2003
- Genetic Manipulation Of Age Dependent Traits In Transgenic Mice Expressing APPNational Institute On Aging1999–2002
- The Biology Of Alzheimers Disease In Transgenic MiceNational Institute On Aging1999
- Toward A Model Of Alzheimers DiseaseNational Institute Of Neurological Disorders And Stroke1994–1998
- Molecular Pathophysiology Of PRP And APP MutantsNational Institute On Aging1995–1997
- Prion Protein Mutations In Inherited Prion DiseasesNational Institute Of Neurological Disorders And Stroke1992–1994
- Prion Protein Mutations In Inherited Prion DiseasesNational Institute Of Neurological Disorders And Stroke1990–1992
- Genetics Of The Human Prion Protein GeneNational Institute Of General Medical Sciences1986–1988
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