JuliaCTchouMDPhD

PubMed

• 18 citations
  Breast reconstruction in bilateral prophylactic mastectomy patients: factors that influence decision making.
  Jonas A. Nelson, Julia Tchou, Susan M. Domchek, Seema S. Sonnad, Joseph M. Serletti
  Journal of Plastic, Reconstructive & Aesthetic Surgery. 2012-11-01
• 544 citations
  8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.
  Julia Tchou, H. Kasai, Shinya Shibutani, Myung-Hee Chung, J. Laval
  Proceedings of the National Academy of Sciences of the United States of America. 1991-06-01
• 182 citations
  Outcomes After Oncoplastic Breast-Conserving Surgery in Breast Cancer Patients: A Systematic Literature Review
  Lucy M. De La Cruz, Stephanie A. Blankenship, Abhishek Chatterjee, Rula Geha, Nadia F. Nocera
  Annals of Surgical Oncology. 2016-06-29

Journal Articles

• Breast Density Changes with Weight Gain/Loss After Bariatric Surgery  
  Kristoffel R Dumon, Julia C Tchou, Journal of The American College of Surgeons
• Should Pseudoangiomatous Stromal Hyperplasia Found on Core Biopsy Be Excised?  
  Julia Tchou, MD, Journal of The American College of Surgeons
• Enhanced Recovery After Surgery Protocol Reduces Perioperative Narcotic Requirement in Patients Undergoing Mastectomy with Implant-Based Reconstruction  
  Julia Tchou, MD, Journal of The American College of Surgeons
• Gestational Gigantomastia Complicated by PTHrP-Mediated Hypercalcemia  
  Julia Tchou, MD, The Journal of Clinical Endocrinology and Metabolism
• Is Age Trumping Genetic Profiling in Clinical Practice? Relationship of Chemotherapy Recommendation and Oncotype DX Recurrence Score in Patients Aged < 50 Years Versus...  
  Julia Tchou, MD, Annals of Surgical Oncology
• Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer  
  Austin D Williams, Amy S Clark, Paul J Zhang, Julia Tchou, Bruce L Levine, Jennifer M Matro, Laurence J Cooper, Alycia So, Lynn M Schuchter, Carl H June, Angela M DeMi..., Clinical Cancer Research
• Mammographic Breast Density Decreases After Bariatric Surgery  
  Mitchell Schnall, Noel Williams, Alycia So, Julia Tchou, Kristoffel Dumon, Breast Cancer Research and Treatment
• Impact of preoperative magnetic resonance imaging (MrI), lumpectomy cavity shaving, and surgeon practice on re-excision rate in pure ductal carcinoma in situ  
  So A, De La Cruz L, Williams AD, Bahng J, Liao G, McDonald E, Fisher CS, Czerniecki BJ, Sataloff D, Tchou J, J Surg Oncol, 1/11/2017
• Safey and efficacy of intratumoral injections of chimeric antigen receptor (CAR) T cells in metastatic breast cancer  
  Tchou J, Zhao Y, Levine BL, Zhang PJ, Davis MM, Melenhorst JJ, Kulikovskaya I, Brennan AL, Liu X, Lacey SF, Posey A, Williams AD, So A, Conejo-Garcia JR, Plesa G, Youn..., Cancer Immunology Research, 1/6/2017
• Immunotherapy for breast cancer - current and future stragies  
  Williams AD, Payne KK, Posey AD, Hill C, Conejo-Garcia J, June CH, Tchou J, Current Surgery Reports, 1/1/2017
• Reliable prediction of postmastectomy lymphedema: The Risk Assessment Tool Evaluating Lymphedema  
  Basta MN, Wu LC, Kanchwala SK, Serletti JM, Tchou JC, Kovach SJ, Fosnot J, Fischer JP, Am J Surg, 1/1/2017
• Evaluating the Risk of Upstaging HER2-Positive DCIS to Invasive Breast Cancer  
  Mustafa RE, DeStefano LM, Bahng J, Yoon-Flannery K, Fisher CS, Zhang PJ, Tchou J, Czerniecki BJ, De La Cruz LM, Ann Surg Oncol, 1/1/2017
• Breast cancer subtype distribution is different in normal weight, overweight, and obese women  
  Gershuni V, Li YR, Williams AD, So A, Steel L, Carrigan E, Tchou J, Breast Cancer Res Treat, 1/1/2017
• Mammographic breast density decreases after bariatric surgery  
  Williams AD, So A, Synnestvedt M, Tewksbury CM, Kontos D, Hsiehm M-K, Pantalone L, Conant EF, Schnall M, Dumon K, Williams N, Tchou J, Breast Cancer Res Treat, 1/1/2017
• Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells  
  Svoronos N, Perales-Puchalt A, Allegrezza MJ, Rutkowski MR, Payne KK, Tesone AJ, Nguyen JM, Curiel TJ, Cadungog MG, Singhal S, Eruslanov EB, Zhang P, Tchou J, Zhang R,..., Cancer Discov, 1/1/2017
• Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target  
  Perales-Puchalt A, Svoronos N, Rutkowski MR, Allegrezza MJ, Tesone AJ, Payne KK, Wickramasinghe J, Nguyen JM, O’Brien SW, Gumireddy K, Huang Q, Cadungog MG, Connolly D..., Clin Cancer Res, 1/1/2017
• Oncologic Safety of Prophylactic Nipple-Sparing Mastectomy in a Population With BRCA Mutations: A Multi-institutional Study  
  Jakub JW, Peled AW, Gray RJ, Greenup RA, Kiluk J V, Sacchini V, McLaughlin SA, Tchou JC, Vierkant RA, Degnim AC, Willey S, JAMA Surg, 1/1/2017
• IL15 Agonists Overcome the Immunosuppressive Effects of MEK Inhibitors  
  Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Tesone AJ, Perales-Puchalt A, Nguyen JM, Sarmin F, Sheen MR, Jeng EK, Tchou J, Wong HC, Fiering SN, Conejo-Garcia JR, Cancer Res, 1/1/2016
• Clinical Diagnosis and Management of Breast Cancer  
  McDonald ES, Clark AS, Tchou J, Zhang P, Freedman GM, J Nucl Med, 1/1/2016
• Optical redox imaging indices discriminate human breast cancer from normal tissues  
  Xu HN, Tchou J, Feng M, Zhao H, Li LZ, J Biomed Opt, 1/1/2016
• Obesity and breast cancer: a complex relationship  
  Gershuni VM, Ahima RS, Tchou J, Current Surgery Reports, 1/1/2016
• Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis  
  Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Perales-Puchalt A, Nguyen JM, Payne KK, Singhal S, Eruslanov EB, Tchou J, Conejo-Garcia JR, Cancer Res, 1/1/2016
• Early Postoperative Outcomes in Breast Conservation Surgery Versus Simple Mastectomy with Implant Reconstruction: A NSQIP Analysis of 11,645 Patients  
  Pyfer B, Chatterjee A, Chen L, Nigriny J, Czerniecki B, Tchou J, Fisher C, Ann Surg Oncol, 1/1/2016
• Outcomes After Oncoplastic Breast-Conserving Surgery in Breast Cancer Patients: A Systematic Literature Review  
  De La Cruz L, Blankenship SA, Chatterjee A, Geha R, Nocera N, Czerniecki BJ, Tchou J, Fisher CS, Ann Surg Oncol, 1/1/2016
• Monitoring serum HER2 levels in breast cancer patients  
  Tchou J, Lam L, Li YR, Edwards C, Ky B, Zhang H, Springerplus, 1/1/2015
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Books/Book Chapters

• Proceedings of International Workshop on Breast Imaging (IWDM), Lecture Notes in Computer Science (LNCS). 
  Chapter: Mammographic parenchymal texture analysis for estrogen-receptor subtype specific breast cancer risk estimation. 
  Page 596 - 603Karemore G, Keller B, Oh H, Tchou J, Nielsen M, Conant E, Kontos DEditors: Maidment ADA, Bakic PR, Gavenonis S.Springer-Verlag, Berlin Heidelberg2012
• Diseases of the Breast. 
  Chapter: Local-Regional Recurrence after Breast-Conservation Treatment or Mastectomy. 
  Page 840 - 855Solin L, Harris E, Weinstein S, DeMichele A, and Tchou JEditors: Harris J, Morrow M, Lippman M, Osborne C.Lippincott Williams & Wilkins, a Wolters Kluwer business, Philadelphia, PAEdition 4th,2010
• The Surgical Review. 
  Chapter: The breast. 
  Page 502 - 517Kruper L, Tchou JEditors: Atluri P, Karakousis GC, Porrett PM, Kaiser LR.Lippincott Williams & Wilkins, Philadelphia, PAEdition 2nd,2006
• Managing Breast Cancer Risk. 
  Chapter: Overview of clinical risk assessment. 
  Page 3 - 25Tchou J, Morrow MEditors: Morrow M, Jordan VC.BC Decker, Hamilton, Ontario, Canada2003
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Abstracts/Posters

• Tn-MUC1 – a novel chimeric antigen receptor T cell (CAR T) therapy target for breast cancer.
  Williams AD, Posey AD, June CH, Tchou J, Society of Surgical Oncology 71th Annual Cancer Symposium, Chicago, IL, 1/21/2018
• A retrospective case-control comparison of breast cancer incidence in obese women undergoing bariatric surgery.
  Williams AD, Hill C, Goldbach M, Malinovitch A, Tchou J, Society of Surgical Oncology 71th Annual Cancer Symposium, Chicago, IL, 1/21/2018
• Changing Practice Patterns of Adjuvant Radiation Among Elderly women with early stage breast cancer in the United States from 2004-2014.
  Reyes, SA, Williams AD, Arlow RL, De La Cruz LM, Anderson D, Ugras S, Brooks AD, Sataloff D, Freedman GM, Tchou J, Society of Surgical Oncology 71th Annual Cancer Symposium, Chicago, IL, 1/21/2018
• National trends in radiation treatment for DCIS.
  Arlow RL, Williams AD, Reyes S, Yoon-Flannery K, Mustafa R, De La Cruz LM, Anderson DN, Ugras S, Brooks AD, Sataloff D, Freedman GM, Tchou J, Society of Surgical Oncology 71th Annual Cancer Symposium, Chicago, IL, 1/21/2018
• Characterization of novel immune checkpoint receptors within the breast cancer tumor microenvironment.
  Williams AD, Payne KK, So A, Conejo-Garcia J, Tchou J, American College of Surgeons Clinical Congress, San Diego, CA, 1/22/2017
• Mammographic Breast Density Decreases After Bariatric Surgery.
  Williams A, So A, Synnestvedt M, Tewksbury CM, Kontos D, Conant E, Schnall M, Dumon K, Williams, Tchou J, Society of Surgical Oncology 70th Annual Cancer Symposium, Seattle, WA, 1/15/2017
• Magnetic resonance imaging features as predictors of non-pathologic complete response to neoadjuvant chemotherapy in patients with triple-negative breast cancer– a cas...
  So A, Williams A, Liao G, McDonald E, Ugras S, Zhang PJ, Tchou J, Society of Surgical Oncology 70th Annual Cancer Symposium, Seattle, WA, 1/15/2017
• Reducing the re-excision rate in DCIS: How does the use (or not) of cavity shave margins and preoperative MRI with partial mastectomy patients impact outcomes.
  So A, De La Cruz L, McMillan M, Williams A, Fisher CS, Tchou J, Society of Surgical Oncology 70th Annual Cancer Symposium, Seattle, WA, 1/15/2017
• Does exogenous insulin contribute to the development of more aggressive subtypes of breast cancer?
  Gershuni V, Li YR, Steel L, Carrigan E, Ro V, Tchou J, American Society of Breast Surgeons 17th Annual Meeting, Dallas, TX, 1/13/2016
• Preventative health maintenance and screening adherence amongst breast cancer survivors.
  Bozzuto L, Li YR, Steel L, Carrigan E, Ro V, Tchou J, American Society of Breast Surgeons 17th Annual Meeting, Dallas, TX, 1/13/2016
• Relationship between BMI and breast cancer subtype.
  Gershuni V, Li YR, Steel L, Carrigan E, Ro V, Tchou J, Society of Surgical Oncology’s 69th Annual Cancer Symposium, Boston, MA, 1/3/2016
• Do minority women wait longer for their definitive breast cancer surgery.
  Steel L, Li YR, Carrigan E, Nguyen J, Ro V, Tchou J, Academic Surgical Congress, Jacksonville, FL, 1/2/2016
• Impact of aspirin use on invasive breast cancer clinical outcomes.
  Li YR, Steel L, Carrigan E, Tchou J, San Antonio Breast Cancer Conference, 1/10/2015
• Redox biomarkers for breast cancer diagnosis and prognosis: two pilot studies of clinical specimens.
  Xu, HN, Tchou J, Feng M, Zhao HQ, Sun N, Zhang S, Moon L, Li LZ, ISOTT conference, Wuhan, People's Republic of China, 1/1/2015
• Differentiating cancerous from normal breast tissue by redox imaging.
  Xe HN, Tchou J, Feng M, Li LZ, Biophotonics imaging conference, San Francisco, CA, 1/1/2015
• Mesothelin expression is associated with poor outcomes in breast cancer.
  Li, YR, Xian RR, Ziober A, Conejo-Garcia J, Perales-Puchalt, June CH, Tchou J, ASCO Annual Meeting, Chicago, IL, 1/31/2014
• A Novel Technique for Near Infrared (NIR) Intraoperative Imaging of Breast Cancer and Sentinel Lymph Nodes (SLNs).
  Okusanya OT, Judy B, Venegas O, Quatromoni J, Singhal S, Tchou J, American College of Surgeons’ 99th clinical Congress, Washington, DC, 1/7/2013
• African American women with breast cancer show higher expression of the targetable cell surface protein Mesothelin.
  Xian R, Tchou J, Ziober A, Vonderheide R, June C, Zhang PJ, 102nd United States and Canadian Academy of Pathology Annual Meeting, Baltimore, MD, 1/2/2013
• Evaluation of margin index for prediction of residual disease after breast-conserving surgery: Can it be a useful tool for the breast surgeon?
  Edwards C, Freedman G, Czernieck B, Tchou J, Fisher CS, American Society of Breast Surgeons Annual Meeting, Chicago, IL, 1/1/2013
• Monitoring soluble Her2 extracellular domain in the serum of breast cancer patients using a refined ELISA Assay.
  Edwards C, Ky B, Tchou J, Zhang H, Society of Surgical Oncology Annual Meeting, Washington, DC, 1/1/2013
• Association between metformin use and improved survival in breast cancer patients: a population-based study.
  Li Y and Tchou J, San Antonio Breast Cancer Conference, San Antonio, TX, 1/1/2013
• Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.
  Tchou J, Kossenkov AV, Chang L, Satija C, Herlyn M, Showe LC, Pure E, American Society of Breast Surgeons Annual Meeting, Phoenix, AZ, 1/2/2012
• Computer-aided Parenchymal Texture Analysis in Digital Mammograms: The Potential for Estrogen-Receptor Specific Breast Cancer Risk Estimation.
  Karemore G, Hue N, Keller B, Tchou J, Conant E, Kontos D, RSNA 97th Scientific Assembly and Annual Meeting, McCormick Place, Chicago, IL, 1/27/2011
• Significance of FAP, SMA and CD31 expression in the stroma of breast.
  Tchou J, Satija C, Zhang P, Bi YT, Chen HY, Majumdar R, Chang L, Davuluri R, Showe L, Mies C, Herlyn M, and Pure E, CTRC-AACR San Antonio Breast Cancer Symposium, San Antonio, TX, 1/7/2011
• Bilateral prophylactic mastectomy and breast reconstruction: What influences the decision?
  Nelson JA, Domchek SM, Tchou J, Serletti JM, Wu LC, 54th Annual Meeting of the Ohio Valley Society of Plastic Surgeons conjoined with the Ivy Society of Plastic Surgery, White Sulfur Springs, WV, 1/2/2011
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Lectures

• CAR T cells as novel therapy for breast cancer 
  Hangzhou, Xiejiang, China - 1/29/2017
• Final analysis of a randomized phase 1b trial to asses sequencing of the E39 and E39’ vaccines to optimize long-term antitumor immunity in folate binding protein (FBP)... 
  San Diego, CA - 1/26/2017
• Immunotherapy as novel treatment strategy for breast cancer 
  National Constitution Center, Philadelphia, PA - 1/22/2017
• CAR T cells directed against c-Met induces tumor necrosis and inflammatory responses in metastatic breast cancer 
  Seattle, WA - 1/17/2017
• Updates in Breast Cancer Research 
  Philadelphia, PA - 1/16/2017
• Surgery – how your team works together to decide the best approach for you 
  Hilton Philadelphia City Avenue, Philadelphia, PA - 1/13/2017
• Current State of Metastatic Breast Cancer Research 
  Philadelphia, PA - 1/17/2016
• Breast cancer – the case for immunotherapy 
  Wistar Institute, Philadelphia - 1/10/2016
• Breakthroughs in Breast Cancer Research, What stakeholders need to know 
  Wistar Institute, Philadelphia - 1/9/2016
• Managing the diagnostic work-up and referral process 
  Hilton Hotel, Philadelphia, PA - 1/22/2015
• Targeted therapy for triple negative breast cancer 
  University of Colorado, Denver - 1/20/2015
• New Surgical Advances: Glowing Tumors and lymph node transfer 
  Philadelphia, PA - 1/9/2015
• Impact of aspirin use on invasive breast cancer clinical outcomes 
  San Antonio, TX - 1/9/2015
• Mulitdisciplinary update on breast cancer – screening and treatment approaches 
  Valley Forge Abramson Cancer Center, PA - 1/5/2014
• Targeting breast cancer using CAR T cells 
  Perelman School of Medicine at University of Pennsylvania - 1/2/2013
• Mesothelin, a novel immunotherapy target for triple negative breast cancer 
  Seven Springs, PA - 1/24/2012
• Management of breast symptoms - Surgeon's perspective 
  Drexel University, Philadelphia, PA - 1/28/2011
• Surgical Management of Breast Cancer 
  Roxborough Memorial Hospital, Philadelphia, PA - 1/19/2011
• Pilot Clinical Trial of autologous Met Redirected T cells administered intratumorallly and intravenously in patients with operable triple negative breast cancer. 
  Bethesda, MD - 1/13/2011
• Surgical Approaches in Breast Cancer Treatment. 
  Delaware State University, Dover, DE - 1/29/2010
• Breast Cancer Symposium 
  Dover, DE - 1/21/2010
• Surgical Forum in Tumor Biology, 
  Washingon, DC - 1/5/2010
• A Breast Surgeon Perspective on DCIS. 
  Arlington, VA - 1/1/2010
• Surgical Approaches to Breast Cancer (Including Sentinel Node) 
  San Juan, Puerto Rico - 1/30/2009
• Surgical Reconstruction Options. 
  San Juan, Puerto Rico - 1/30/2009
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Other

• Breast Cancer Diagnostic Algorithms for Primary Care Providers. 
  Tchou JC, Counter Details, Pennsylvania Medical Society
  1/1/2010
• Dissertation: Repair of DNA containing the oxidatively-damaged base, 8-oxoguanine, by Escherichia coli Fpg protein. 
  Tchou JC
  State University of New York at Stony Brook School of Medicine, Stony Brook, NY - 1/1/1993