Juan Sanchez-Ramos MD

PubMed

• 1 citations
  Measurement of ΔTHC and metabolites in the brain and peripheral tissues after intranasal instillation of a nanoformulation.
  Gunjan Upadhyay, Oksana Fihurka, Connor Habecker, Pranav Patel, Juan Sanchez-Ramos
  Journal of Cannabis Research. 2023-02-07
• 2 citations
  Key Features in the Design and Function of Nanocarriers for Intranasal Administration of Gene Therapy in Huntington Disease.
  Oksana Fihurka, Stephen Aradi, Vasyl Sava, Juan Sanchez-Ramos
  Journal of Nanotechnology and Nanomaterials. 2023-01-01
• 7 citations
  Dual-function hybrid nanoparticles with gene silencing and anti-inflammatory effects.
  Oksana Fihurka, Vasyl Sava, Juan Sanchez-Ramos
  Nanomedicine. 2022-04-01

Journal Articles

• Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials  
  Biglan, K and Huntington Study Group (with J. Sanchez-Ramos), JAMA Neurology, 1/1/2016
• Cannabinoids for the Treatment of Movement Disorders  
  Catlow B, Sanchez-Ramos J, Current Treatment Options in Neurology, 1/1/2015
• Evaluation of an alpha synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson's disease  
  Kenneth E. Ugen, Xiaoyang Lin, Ge Bai, Zhanhua Liang, Jianfeng Caid, Kunyun Li, Shijie Song, Chuanhai Cao & Juan Sanchez-Ramos, Human Vaccines & Immunotherapeutics, 1/1/2015
• Neurologic Complications of Psychomotor Stimulant Abuse  
  Sanchez-Ramos J, International Review of Neurobiology, 1/1/2015
• Examining Huntington's disease patient and informant concordance on frontally mediated behaviors  
  Hergert DC, Sanchez-Ramos J, Cimino CR, Journal of Clinical and Experimental Neuropsychology, 1/1/2015
• Promotion of Brain Self-Repair Mechanisms by Stereotaxic Microneedle Lesions  
  Song, S, Kong, X, Acosta, SA, Sava, V, Borlongan, CV, Sanchez-Ramos, J, Cell Transplantation, 1/1/2015
• The Parkinson's active living (PAL) program: A behavioral intervention targeting apathy in Parkinson's disease  
  Butterfield LC, Cimino CR, Salazar RD, Lee CS, Haley WE, Sanchez-Ramos J, Okun MS, Bowers D, Movement Disorders, 1/1/2015
• The Entourage Effect of the Phyto-cannabinoids  
  Sanchez-Ramos J, Annals of Neurology, 1/1/2015
• Nanoparticles for Direct Nose-to-Brain Delivery of Gene Therapy  
  Sanchez-Ramos J, Song S, Sava V, Neurotherapeutics, 1/1/2015
• The entourage effect of the phytocannabinoids  
  Sanchez-Ramos J, Ann Neurol, 1/1/2015
• In vivo administration of G-CSF restores long term depression (LTD) in hippocampal slices prepared from transgenic APP/PS1 mice  
  Song S, Wang X, Sava V, Weeber E, Sanchez-Ramos J, J Neurosci Res, 1/1/2014
• Combination Therapy of Human Umbilical Cord Blood Cells and Granulocyte Colony Stimulating Factor Reduces Histopathological and Motor Impairments in an Experimental Mo...  
  Acosta, Sandra A., Tajiri, Naoki, Shinozuka, Kazutaka, Ishikawa, Hiroto, Sanberg, Paul R., Sanchez-Ramos, Juan, Song, Shijie, Kaneko, Yuji and Borlongan, Cesar V, PLOS 1, 1/1/2014
• A cognitive assessment battery for clinical trials in Huntington's disease  
  Stout et al (and CAB Investigators including J. Sanchez-Ramos) HD-CAB, Movement Disorders, 1/1/2014
• Direct delivery of gene-silencing molecules into brain by the olfactory route  
  Sanchez-Ramos, J.; Song, S.; Sava, V, Movement Disorders, 1/1/2014
• Hippocampal Neurogenesis and the Brain Repair Response Brief Stereotaxic Insertion of a Micro-needle  
  Shijie Song, Shuojing Song, Chuanhai Cao, Xiaoyang Lin, Kunyu LI, Vasyl Sava and J. Sanchez-Ramos, Stem Cells International, 1/1/2013
• Neuroprotective effects of bone marrow stromal cells in cocultures of fetal dopaminergic neurons  
  Shijie Song, Amanda Rowe, Kunyu Li, Vasyl Sava and J. Sanchez-Ramos, Journal of Neurodegeneration and Regeneration, 1/1/2013
• Effect of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning  
  Briony Catlow, Shijie Song, Daniel Paredes, Cheryl Kirstein and J. Sanchez-Ramos, Exp. Brain Research, 1/1/2013
• Direct Actions of Granulocyte-Colony Stimulating Factor on Human Neuronal and Monocytic Cell Lines  
  Pennington A, Sava V, Song S, Patel N, Sanchez-Ramos J, J Alzheimers Dis Parkinsonism, 1/1/2013
• Safety of tetrabenazine in a longitudinal cohort study of individuals with Huntington disease  
  Nichols P, Darwin K, Brocht A, Dorsey ER, Beck C, Biglan K, and Shoulson I, on behalf of the Huntington Study Group COHORT Investigators, Neurotherapeutics, 1/1/2013
• Treatment of chorea in Huntington disease  
  Darwin K, Nichols P, Brocht A, Dorsey ER, Beck C, Biglan K, and Shoulson I, on behalf of the Huntington Study Group COHORT Investigators, Neurotherapeutics, 1/1/2013
• Natural History of Huntington's Disease  
  Dorsey ER, Beck CA, Darwin K, Nichols P, Brocht AF, Biglan KM, Shoulson I; Huntington Study Group COHORT Investigator, JAMA Neurol, 1/1/2013
• Characterisation of a large group of individuals with Huntington's disease and their relatives enrolled in the COHORT study—a longitudinal analysis of data  
  Goh A, Loi S, Antonopoulos S, Chiu E, and the HSG COHORT investigators and coordinators, Neurotherapeutics, 1/1/2013
• Recruitment and retention challenges in 2CARE, a long-term therapeutic clinical trial of coenzyme Q10 in Huntington's disease  
  Cudkowicz M, McDermott M, Kieburtz K, McGarry A, de Blieck E, and the 2CARE Investigators and Coordinators of the Huntington Study Group, Neurotherapeutics, 1/1/2013
• A Randomized, Double-Blind, Placebo-Controlled Trial of Pridopidine in Huntington's Disease  
  Huntington Study Group HART Investigators (with J. Sanchez-Ramos), Movement Disorders, 1/1/2013
• Relationship of Mediterranean diet and caloric intake to phenoconversion in Huntington disease  
  Marder K, Gu Y, Eberly S, Tanner CM, Scarmeas N, Oakes D, Shoulson I; Huntington Study Group PHAROS Investigators, JAMA Neurol, 1/1/2013
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Books/Book Chapters

• The Pot Book 
  Chapter: Cannabinoids for the treatment of Movement Disorders 
  O'Neill C and Sanchez-Ramos JEditors: Julie Holland, MD.2013
• Movement Disorders: Unforgettable Cases and Lessons from the Bedside 
  Chapter: Discrepancy in CAG Repeat Lengths in a Case of Clinically Manifest Huntington's Disease. 
  Sanchez-Ramos, JEditors: H. H. Fernandez and M Merello.Demos Medical, NY2012
• Handbook of Clinical Neurology (Series 3) Movement Disorders Volume 
  Chapter: Hyperkinetic Movement Disorders Associated with HIV and other Viral Infections 
  Page 323 - 334Carroll, E and Sanchez-Ramos JEditors: Weiner and Tolosa.2011
• Drug-Induced Movement Disorders 
  Chapter: Stimulant-Induced Movement Disorders 
  Sanchez-Ramos JEditors: K. Sethi.Marcel Dekker, Inc., New York, Basel2004
• (Methods in Molecular Biology) Protocols for Neural Stem Cell Methods 
  Chapter: Preparation of Neural Progenitors from Bone Marrow and Umbilical Cord Blood. 
  Page 79 - 88Song S, and Sanchez-Ramos JEditors: T. Zigova, P. Sanberg, and J. Sanchez-Ramos.Humana Press, Totowa, NJ2002
• Neural Stem Cells (Methods in Molecular Biology) 
  Chapter: The Search for Neural Progenitors in Bone Marrow and Umbilical Cord Blood 
  Song S, Sanberg P and Sanchez-Ramos JEditors: T. Zigova and P. Sanberg.Humana, Totowa, NJ2002
• Neurotoxic Factors in Parkinson's Disease and Related Disorders 
  Chapter: Relationship of Organochlorine Pesticides to Parkinsonism 
  Page 237 - 246Song S, Cardozo-Pelaez F, and Sanchez-Ramos, JEditors: Collins and Storch.Kluwer Academic/Plenum2001
• Parkinsons' Disease, Advances in Neurology 
  Chapter: Traditional Therapies of Parkinson's disease. 
  Page 565 - 571Manyam B and Sanchez-Ramos JEditors: G. Stern.1999
• Parkinson's Disease 
  Chapter: Motor Complications of Levodopa therapy. 
  Sanchez-Ramos, J.Editors: M. Merello, AJ. Lees.Talleres Graficos de "La Ley" S.A.E., Buenos Aires, Argentina1999
• The Neurology of Drugs of Abuse Cocaine, Ibogaine and Substituted Amphetamines (Annals NY Acad Sci) 
  Chapter: Medication development of ibogaine as a pharmacotherapy for drug dependence. 
  Page 275 - 292Mash DC, Kovera CA, Buck BE, Norenberg MD, Phapshak P, Hearn WL, Sanchez-Ramos J.Editors: Syed Ali.Annals NY Acad Sci1998
• Beyond Decade of the Brain, Vol 2 Dopamine Agonists in Early Parkinson's Disease 
  Chapter: High dose pergolide therapy in the treatment of severe dyskinesias in Parkinson's disease. 
  Page 217 - 221Sanchez-Ramos, J.Editors: C. Warren Olanow, J. A. Obeso.Wells Medical Limited, Kent, UK1997
• "Posterior Circulation Vascular Disease" 
  Chapter: "Medical Illustrations" 
  Sanchez-Ramos J, L. CaplanBlackwell Science, Boston1996
• Constructive Potentials of Psychedelics: Cross-cultural Perspectives. Yearbook of Cross-Cultural Medicine and Psychotherapy Volume 4 
  Chapter: Pharmacotherapy of drug dependence with ibogaine. 
  Sanchez-Ramos, J. and Mash DEditors: M. Winkelman, W Andritzky.1996
• Stereotypies: Brain-Behavior Relationships 
  Chapter: Stereotyped Behavior in Movement Disorders 
  Shulman LM, Sanchez-Ramos J, Weiner WJEditors: Sprague RL and Newell KM.1996
• Neurology in Clinical Practice 
  Chapter: Neurological Complications of Drugs of Abuse 
  Page 1402 - 1414Sanchez-Ramos, J.Editors: Bradley WG, Daroff RB, Fenichel GM, Marsden CD.Butterworth-Heinemann1996
• Pharmacology of Cerebral Ischemia 
  Chapter: Excitotoxic and ischemic damage: role of nitric oxide. 
  Page 363 - 373Globus MYT, Prado R, Sanchez-Ramos J, Dietrich WD, Ginsberg MD, Busto REditors: J Krieglstein, H Oberpichler-Schwenk.Wissenschaftliche Verlagsgesellschaft, Stuttgart1994
• Neurologic Clinics, Neurologic Complications of Drug and Alcohol Abuse 
  Chapter: Psychostimulants. 
  Page 535 - 553Sanchez-Ramos, J.Editors: J. Brust.WB Saunders, NY1993
• Parkinsonian Syndromes 
  Page 155 - 171Editors: M. Stern, WC Koller.Raven Press, NY1992
•  
  Editors: WJ Weiner and A. Lang.Futura Press, Mt Kisco, NY1992
• Handbook of Tourette's Syndrome and Related Tic and Behavioral Disorders 
  Editors: R. Kurlan.Marcel Dekker, Inc.1992
• XIth International Symposium on Posture and Gait 
  Chapter: Gait abnormality in essential tremor. 
  Page 147 - 151Singer C, Sanchez-Ramos J, Weiner WJEditors: M. Woollacott and F. Horak.University of Oregon Books1992
• Progress in Parkinson Research 
  Chapter: Platelet membrane fluidity in Parkinson's disease. 
  Page 39 - 47Editors: Hefti F, and Weiner WJ.Futura Pub Co, NY1992
• Parkinson's Disease: From Basic Research To Treatment 
  Chapter: Transferrin receptor regulation in Parkinson's disease and MPTP-treated mice. 
  Mash DC, Sanchez-Ramos J., Weiner WJEditors: H. Narabayashi, T. Nagatsu, N. Yanagisawa, Y. Mizuno.Raven Press, NY1992
• Urgent and Emergent Neurology 
  Chapter: Neurological Emergencies Related to Drugs of Dependence 
  Page 487 - 508Editors: W. J. Weiner.Lippincott, Philadelphia1991
• Neuroprotective Therapy in Early Parkinson's Disease 
  Chapter: Effect of selegiline (L-deprenyl) on the progression of disability in early Parkinson's disease: a preliminary report. 
  Page 25 - 32Shoulson I and the Parkinson Study Group (with J. Sanchez-Ramos)Editors: UK Rinne, E. Heinonen.Orion Corp, Farmos, Turku, Finland1991
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Abstracts/Posters

• Relationship Between Affective and Cognitive Functioning in At-risk and Presymptomatic Huntington Disease Patients.
  Cimino, CR; Hergert, D; Johnson, P; Sanchez-Ramos, J, Neurotherapeutics, 1/1/2016
• Effects of Bone Marrow Transplantation in a Mouse Model of HD.
  Song S, Sava V and Sanchez-Ramos J, International Symposium on HD, Venice, Italy, 1/1/2013
• Nanoparticles for Delivery of DNA and siRNAinto Brain  by Nasal Insufflation
  Sava V, Aradi S, Song S, Sanchez-Ramos J, International Symposium on HD, Venice, Italy, 1/1/2013
• Development of Chitosan Nanoparticles for Intranasal Delivery of RNA Interference to the Brain
  Stephen Aradi,   Vasyl Sava, Juan Sanchez-Ramos, USF Research Day, 1/1/2013
• Apathy, depression, and cognitive functioning in Parkinson's disease.
  Butterfield, L., Oelke, L. Cimino, C., Hauser, R.  & Sanchez-Ramos, J., Journal of International Neuropsychological Society, 36th Annual Meeting of the International Neuropsychological Society, Atlanta, GA, 2009, 1/29/2009
• Effects of G-CSF in the MPTP Mouse Model of PD.
  Sanchez-Ramos J, Mori T, Sava V, Song S, International Symposium on Movement Disorders, 1/1/2009
• Filgrastim (G-CSF) increases Hippocampal Neurogenesis.
  Sanchez-Ramos J, et al, Society for Neuroscience, 1/18/2008
• G-CSF reduces hippocampal amyloid load and improves performance in a Tg AD Mouse Model.
  Sanchez-Ramos J, Song S, Cao C, Lin X, Mori T, Arendash G, International Conference on Alzheimer's Disease (ICAD), Chicago, IL, 1/1/2008
• Effects of diethyl maleate preconditioning on the expression of DNA repair genes in midbrain elicited by Ochratoxin-A.
  Sava V, Harbison R, Sanchez-Ramos J, Society of Toxicology Symposium, Seattle, WA, 1/1/2008
• Characterization of frontal lobe behavioral syndromes in Huntington's Disease (HD).
  Oelke, L., Butterfield, L., Cimino, C., Sanchez-Ramos, J., McCall, M., Pugliese, L., Ling, L, Stell, B. & Annis, J., Neurotherapeutics: The Journal of the American Society for Experimental NeuroTherapeutics, Second Annual Huntington's Disease Clinical Research Symposium, St. Petersburg, 1/1/2008
• Effects of environmental enrichment on neurogenesis in transgenic PS1/APP mice.
  Catlow, B, Sanchez-Ramos J, G. Arendash, Society for Neuroscience Program, San Diego, CA, 1/1/2007
• Dopaminergic Neurotoxicity Associated With Deficit In Repair Of Oxidative Dna Damage Caused By Ochratoxin-A.
  V. Sava, A. Velasquez, S. Song, J. Sanchez-Ramos, Society for Neurosciences, 1/1/2004
• Hematopoietic and neural antigens in blood-derived progenitors.
  Hudson, J.E., Chen, N., Song, S., Walczak, P., Sanberg, P., Sanchez-Ramos, J., Zigova, T., Keystone Symposium, Stem Cells, Keystone, CO, 1/1/2004
• Distribution Of Oxidative Dna Damage And Oxyguanosine Glycosylase Activities Across Brain Regions Of Mice Injected With A Single Dose Of Rubratoxin - B.
  V.Sava; D.Mosquera; S.Song; K.Calero; R.Harbison; F.Cardozo-Pelaez; J.Sanchez-Ramos, Society for Neurosciences Abs, 1/1/2003
• G-Csf Stimulated Peripheral Blood Mononuclear Cells As A Possible Treatment For Stroke.
  A.E. Willing, J. Mallery, J. Cassady, J. Sanchez-Ramos, P.R. Sanberg, Exp Neurol, American Society for Neural Transplantation and Repair, 1/1/2003
• Neural And Hematopoietic Antigens In Cultured Human Umbilical Cord Cells.
  N. Chen, S. Song, J.E. Hudson, A.E. Willing, S. Garbuzo-Davis, J. Sanchez-Ramos, P. Sanberg, and T. Zigova, Exp Neurol, American Society for Neural Transplantation and Repair, 1/1/2003
• Proliferative Capacity Of Human Umbilical Cord Blood.
  J. E. Hudson, S. Song, N. Chen, P. Walczak, A.E. Willing, S. Saporta, S. Garbuzova-Davis, J. Sanchez-Ramos, P. Sanberg and T. Zigova, Exp Neurol, American Society for Neural Transplantation and Repair, 1/1/2003
• Can Neurogenic Subventricular Zone In Aging Animals Influence Survival, Migration And Differentiation Of Human Umbilical Cord Blood-Derived Progenitors.
  Walczak, S. Song, N. Chen, J.E. Hudson, A.E. Willing, J. Sanchez-Ramos, P.C. Bickford, P.R. Sanberg, and T. Zigova, Exp Neurol, American Society for Neural Transplantation and Repair, 1/1/2003
• Progenitor Cells From Adult Bone Marrow Exhibit Neural Phenotypes In Culture And Migrate Within The Developing Rat Brain.
  E.Hudson; S.Song; N.Chen; P.Walczak; P.Jendelova; A.Willing; C.Phelps; J.Sanchez-Ramos; P.Sanberg; T.Zigova, Society for Neurosciences Abs, 1/1/2003
• Rat Subventricular Zone As A Model To Study Pluripotent Properties Of Human Umbilical Cord Blood Cells.
  P.Walczak; N.Chen; J.E.Hudson; A.E.Willing; S.N.Garbuzova-Davis; J. Sanchez-Ramos; P.C.Bickford; P.R.Sanberg; T.S.Zigova, Society for Neurosciences Abs, 1/1/2003
• Can human umbilical cord blood progenitors expand and sequentially differentiate toward neural lineages?
  N.Chen; S.Song; J.E.Hudson; P.Walczak; A.E.Willing; J.Sanchez-Ramos; P.R.Sanberg; T.Zigova, Society for Neurosciences Abs, 1/1/2003
• Effects Of Melanin And Manganese On Dna Damage And Repair In Pc12 - Derived Neurons.
  D.Mosquera; V.Sava; S.Song; F.Cardozo-Pelaez; J.Sanchez-Ramos, Society for Neurosciences Abs, 1/1/2003
• Proliferation Of Human Umbilical Cord Blood Cells ( Hucb ) In Mitogen - Free Conditions.
  J.E.Hudson, N.Chen, M.S.Almeida, A.E.Willing, S.Saporta, D.W.Cahill, J.Sanchez-Ramos, P.R.Sanberg, T.Zigova, Society for Neuroscience, Washington, DC, 1/1/2002
• Separation of cells expressing nestin and mushashi-1 from human bone marrow and umbilical cord blood.
  Song S, Kamath S, Sanberg PR, Zigova T, Willing A, Goldman SA, and Sanchez-Ramos J, Exp. Neurology, 1/1/2002
• Optimal conditions to study the properties of human umbilical cord blood cells exposed to neuralizing agents.
  Newman M, Sanberg PR, Sanchez-Ramos J, Willing AE, Bickford PC, Manresa J, and T Zigova, Exp Neurology, 1/1/2002
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Lectures

• "Nose-to-Brain Delivery of Gene Therapy" 
  Cambridge, MA - 1/1/2014
• "Art and Science: a Neurologist's Perspective" 
  Tampa Museum of Science and Industry - 1/24/2012
• "Neon Neurons" 
  St. Petersburg, FL - 1/1/2012
• "Effects of Psilocybin and other Serotonin agonists on Hippocampal Neurogenesis" 
  New York, NY - 1/1/2011
• "Effects of G-CSF on Mouse Hippocampal Neurogenesis" 
  Barcelona, FL - 1/8/2009
• "Parkinson's Disease and Fall Risk" 
  Clearwater, FL - 1/6/2009
• "Filgastrim (G-CSF) increases hippocampal neurogenesis" 
  Washington, DC - 1/18/2008
• "G-CSF Reduces Brain Amyloid, Increases Expression of Synaptophysin and Improves Cognition in a Mouse Model of Alzheimer's Disease" 
  1/2/2008
• "Quantitative Tremor Analysis in Welders, Parkinson's Disease and Essential Tremor" 
  Portgual - 1/24/2007
• "Potential of Hematopoietic Agents for Treatment of Alzheimer's Disease" 
  1/15/2007
• "Role Of Neuro D1 In The Generation Of New Neurons In The Adult Brain" 
  1/19/2006
• "Mycotoxins: Low level exposure and subsequent parkinsonism" 
  Sydney, Australia - 1/7/2005
• "Manganese and Parkinsonism" 
  Sydney, Australia - 1/6/2005
• "Toxic Exposure: Precursors to Neurodegenerative Disease" 
  Sydney, Australia - 1/6/2005
• "The Ubiquitous Mycotoxin Ochratoxin B Causes Dopamine Depletion and Alterations in Oxidative DNA Repair in Striatum" 
  Toronto, Canada - 1/1/2004
• "Scientific Advances in Cell-Based Therapy for Brain Injury" 
  Clearwater, FL - 1/7/2003
• "Neurodegenerative Diseases: Disorders of Protein Misfolding?" 
  Acapulco, Mexico - 1/6/2003
• "Clinical Aspects of Parkinson's and Huntington's Disease" 
  Orlando, FL - 1/2/2002
• "Bone Marrow and Umbilical Cord Blood as a Source of Neural Cells" 
  Osaka, Japan - 1/2/2002
• "Advances in Huntington's Disease" 
  University of Basel, Basel Switzerland - 1/26/2001
• "Parkinson's Disease Research Update" 
  University of Basel, Basel Switzerland - 1/25/2001
• "Neural Progenitors from Human Umbilical Cord Blood" 
  London, UK - 1/21/2001
• "Neural Gene Expression in Human Umbilical Cord Blood Cells" 
  Clearwater, FL - 1/1/2001
• "Molecular and Cellular Evidence for Neural Progenitors in Human Umbilical Cord Blood Neurology" 
  Philadelphia, PA - 1/1/2001
• "Adult Bone Marrow Stromal Cells as a Source of Neural Cells" 
  Clearwater, FL - 1/28/2000
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Other

• Estado Actual de la Hipotesis de Los Oxiradicales en la Enfermedad de Parkinson. 
  Sanchez-Ramos J, Anitoxidantes y Calidad de Vida
  Buenos Aires, Argentina - 1/1/1996
• Radicales libres y enfermedades neurodegenerativas. 
  Sanchez-Ramos J, Anitoxidantes y Calidad de Vida
  Buenos Aires, Argentina - 1/1/1995
• Parkinson's Disease Update. 
  Neurology Update, Continuing Medical Education, Corp.
  Princeton - 1/1/1989