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Office
12901 Bruce B Downs Blvd
Mdc 55
Tampa, FL 33612Phone+1 813-974-6022
Summary
- Dr. Juan (Zeno) Sanchez-Ramos, PhD, MD is Professor Emeritus in the Dept of Neurology, University of South Florida. He held the Helen Ellis Endowed Chair from 1996 until retirement in 2024. He is a physician-scientist who received a Ph.D. in Pharmacology and Physiology from the University of Chicago and a medical degree (M.D.) from the University of Illinois. He trained in Neurology at the University of Chicago and as a Fellow in Movement Disorders at the University of Miami. His neuroscience research has included studies of drug dependence, toxicant-induced neurodegeneration, stem cell biology, botanical medications and novel approaches for delivery of gene therapy. He was a member of a team of neurologists, psychologists and geneticists that studied a large Venezulean family with Huntington’s Disease (HD). Based on that extensive field work, the research team discovered the HD gene in 1992. He has served as the Director of the Huntington’s Disease Center of Excellence at USF since 2006 and Director of the Parkinson’s Disease Research Foundation (Sarasota) for 10 years. He has served as Art Editor of Chicago Review, and has illustrated medical publications. He received an Award for his animation entitled “Dancing DNA” sponsored by the University of Chicago Materials Research Center in their annual Sights and Sounds of Science Project (2004). He has received numerous awards including an NIH Clinical Investigator Development Award to start his research lab, the Helen E. Ellis Endowed Chair for Parkinson's Disease Research, USF McNair Scholars Faculty Research Mentor Award, and the University of South Florida Outstanding Faculty Research Achievement Award. He has been awarded 8 US patents including a novel method to treat drug dependence, a method for development of neural cells from bone marrow-derived stem cells, and a novel nanoparticle system to allow nose-to-brain delivery of gene therapy. Publications: Over 300 scientific articles
Education & Training
- University of Miami/Jackson Health SystemFellowship, Neuromuscular Medicine (Neurology), 1985 - 1987
- University of ChicagoResidency, Neurology, 1982 - 1985
- Michael Reese Hospital and Medical CenterInternship, Internal Medicine, 1981 - 1982
- University of Illinois College of MedicineClass of 1981
- University of ChicagoPhD, Behavioral Pharmacology, 1976
- University of ChicagoBS, Biological Sciences, 1967
Certifications & Licensure
- FL State Medical License 1985 - 2027
- IL State Medical License 1982 - 1987
- American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- Clinical Investigator Development Award NIH
- CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2013
- Award for Animation entitled "Dancing DNA" Annual Sights and Sounds of Science Project, 2004
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Clinical Trials
- Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E) Start of enrollment: 2009 Sep 01
- Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort Start of enrollment: 2012 Jul 01
Publications & Presentations
PubMed
- 1 citationsMeasurement of ΔTHC and metabolites in the brain and peripheral tissues after intranasal instillation of a nanoformulation.Gunjan Upadhyay, Oksana Fihurka, Connor Habecker, Pranav Patel, Juan Sanchez-Ramos
Journal of Cannabis Research. 2023-02-07 - 2 citationsKey Features in the Design and Function of Nanocarriers for Intranasal Administration of Gene Therapy in Huntington Disease.Oksana Fihurka, Stephen Aradi, Vasyl Sava, Juan Sanchez-Ramos
Journal of Nanotechnology and Nanomaterials. 2023-01-01 - 7 citationsDual-function hybrid nanoparticles with gene silencing and anti-inflammatory effects.Oksana Fihurka, Vasyl Sava, Juan Sanchez-Ramos
Nanomedicine. 2022-04-01
Journal Articles
- Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical TrialsBiglan, K and Huntington Study Group (with J. Sanchez-Ramos), JAMA Neurology, 1/1/2016
- Cannabinoids for the Treatment of Movement DisordersCatlow B, Sanchez-Ramos J, Current Treatment Options in Neurology, 1/1/2015
- Evaluation of an alpha synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson's diseaseKenneth E. Ugen, Xiaoyang Lin, Ge Bai, Zhanhua Liang, Jianfeng Caid, Kunyun Li, Shijie Song, Chuanhai Cao & Juan Sanchez-Ramos, Human Vaccines & Immunotherapeutics, 1/1/2015
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Books/Book Chapters
Abstracts/Posters
- Relationship Between Affective and Cognitive Functioning in At-risk and Presymptomatic Huntington Disease Patients.Cimino, CR; Hergert, D; Johnson, P; Sanchez-Ramos, J, Neurotherapeutics, 1/1/2016
- Effects of Bone Marrow Transplantation in a Mouse Model of HD.Song S, Sava V and Sanchez-Ramos J, International Symposium on HD, Venice, Italy, 1/1/2013
- Nanoparticles for Delivery of DNA and siRNAinto Brain by Nasal InsufflationSava V, Aradi S, Song S, Sanchez-Ramos J, International Symposium on HD, Venice, Italy, 1/1/2013
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Lectures
- "Nose-to-Brain Delivery of Gene Therapy"Cambridge, MA - 1/1/2014
- "Art and Science: a Neurologist's Perspective"Tampa Museum of Science and Industry - 1/24/2012
- "Neon Neurons"St. Petersburg, FL - 1/1/2012
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Other
- Estado Actual de la Hipotesis de Los Oxiradicales en la Enfermedad de Parkinson.Sanchez-Ramos J, Anitoxidantes y Calidad de Vida
Buenos Aires, Argentina - 1/1/1996 - Radicales libres y enfermedades neurodegenerativas.Sanchez-Ramos J, Anitoxidantes y Calidad de Vida
Buenos Aires, Argentina - 1/1/1995 - Parkinson's Disease Update.Neurology Update, Continuing Medical Education, Corp.
Princeton - 1/1/1989
Press Mentions
- University of South Florida Participates in Phase III Clinical Trial Targeting Huntington’s DiseaseSeptember 5th, 2019
- Neurogenesis Our Foundation of Present ,Past and Future Human IntelligenceApril 21st, 2017
Professional Memberships
- Member
Other Languages
- Spanish, French
External Links
- Faculty listinghttp://health.usf.edu/medicine/neurology/profiles/9497/Juan-Sanchez-Ramos.aspx
- Zeno Art and Designhttp://zenografia.com
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