JuanManuelOrtega legaspiMD, PhD

PubMed

• Safety and Efficacy of GLP-1 Agonists in a Cohort of Patients with Fontan Circulation.
  Andrew M Freddo, Humera Ahmed, Jonathan B Edelson, Juan M Ortega-Legaspi, Sumeet Vaikunth
  Pediatric Cardiology. 2024-11-12
• Hemodynamic Support With the Impella 5.5 Acute Mechanical Circulatory Support Device.
  James W Schurr, Adrian Pearson, Matthew S Delfiner, Alyson Brown, Mary Frances Quinn
  ASAIO Journal. 2024-10-15
• 1 citations
  Mortality and morbidity after combined heart and liver transplantation in the failing Fontan: An updated dual center retrospective study.
  Sumeet S Vaikunth, Juan M Ortega-Legaspi, Desiree R Conrad, Sharon Chen, Tami Daugherty
  Clinical Transplantation. 2024-04-01

Journal Articles

• Acute myocarditis following high-dose interleukin-2 treatment  
  Tan MChC, Ortega-Legaspi JM, Cheng SF, Patton KK, J Cardiol Cases, 1/1/2017
• Prevalence of resistant hypertension and eligibility for catheter-based renal denervation in hypertensive outpatients  
  Hayek SS, Abdou MH, Demoss BD, Ortega-Legaspi JM, Veledar E, Deka A, Krishnan SK, Wilmot KA, Patel AD, Kumar VR, Devireddy CM, Am J Hypertens, 1/1/2013
• Alginate microencapsulation of human mesenchymal stem cells as a strategy to enhance paracrine-mediated vascular recovery after hind limb ischemia  
  Landázuri N, Levit RD, Joseph G, Ortega-Legaspi JM, Flores CA, Weiss D, Sambanis A, Weber CJ, Safley SA, Taylor WR, J Tissue Eng Regen Med, 1/21/2012
• Insular Cortex Lesion Diminishes Neuropathic and Inflammatory Pain-Like Behaviours  
  Coffeen U, Ortega-Legaspi JM, López-Muñoz FJ, Simón-Arceo K, Jaimes O, Pellicer F, Eur J Pain, 1/1/2011
• Expression of the dopaminergic D1 and D2 receptors in the anterior cingulate cortex in a model of neuropathic pain  
  Ortega-Legaspi JM, de Gortari P, Garduño-Gutiérrez R, Amaya MI, León-Olea M, Coffeen U, Pellicer F, Mol Pain, 1/1/2011
• Expression of muscarinic M1 and M2 receptors in the anterior cingulate cortex associated with neuropathic pain  
  Ortega-Legaspi JM, León-Olea M, de Gortari P, Amaya MI, Coffeen U, Simón-Arceo K, Pellicer F, Eur J Pain, 1/1/2010
• Inflammatory nociception diminishes dopamine release and increases dopamine D2 receptor mRNA in the rat's insular cortex  
  Coffeen U, Ortega-Legaspi JM, de Gortari P, Simón-Arceo K, Jaimes O, Amaya MI, Pellicer F, Mol Pain, 1/1/2010
• Dopamine receptors in the anterior insular cortex modulate long-term nociception in the rat  
  Coffeen U, López-Avila A, Ortega-Legaspi JM, del Angel R, López-Muñoz FJ, Pellicer F, Eur J Pain, 1/1/2008
• Taurine in the anterior cingulate cortex diminishes neuropathic nociception: a possible interaction with the glycineA receptor  
  Pellicer F, López-Avila A., Coffeen U., Ortega-Legaspi JM., del Ángel R, Eur J Pain, 1/1/2007
• The nightmare of a painful phantom  
  Ortega-Legaspi JM, Salud Mental, 1/1/2007
• Dopamine and NMDA systems modulate long-term nociception in the rat anterior cingulate cortex  
  López-Avila A., Coffeen U., Ortega-Legaspi JM., del Ángel R., Pellicer F, Pain, 1/1/2004
• Scopolamine into the anterior cingulate cortex diminishes nociception in a neuropathic pain model in the rat: an interruption of ‘nociception-related memory acquisition’?  
  Ortega-Legaspi JM., López-Avila A., Coffeen U., del Ángel R., Pellicer F, Eur J Pain, 1/1/2003
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Books/Book Chapters

• Dopamine: Functions, Regulation and Health Effects 
  Chapter: Dopamine and Pain Modulation in the Insular Cortex 
  Coffeen U, Ortega-Legaspi JM, Pellicer FEditors: Kudo E, Fujii Y.Nova Science Publishers, Inc., New York, NY2012
• Pharmacology of Pain 
  Chapter: Dopamine Pathways and Receptors in Nociception and Pain 
  Pellicer F., Ortega-Legaspi JM., López-Avila A., Coffeen U., Jaimes OEditors: Beaulieu P., Lussier D., Porreca F., Dickenson AH.IASP Press, Seattle WA2010
• Proceedings of the 3rd International Congress on Neuropathic Pain – NeuPSIG 
  Chapter: Changes of Dopaminergic D1 and D2 Receptor mRNA levels in the Anterior Cingulate Cortex are Associated with Neuropathic Nociception 
  Ortega-Legaspi JM., de Gortari P., Amaya MI., Pellicer FEditors: Wells CD.Medimond S.r.l - Monduzzi Editore2010
• Guía Exarmed (para el Examen de Aspirantes a Residencias Médicas) 
  Chapter: Enfermedad vascular cerebral. (Cerebral Vascular Disease) 
  Ortega-Legaspi JM., López-Avila AEditors: González Quesada CJ., Romano Munive AF.Intersistemas, México2008
• Guía Exarmed (para el Examen de Aspirantes a Residencias Médicas) 
  Chapter: Epilepsia. (Epilepsy) 
  Ortega-Legaspi JM., López-Avila AEditors: González Quesada CJ., Romano Munive AF.Intersistemas, México2008
• Guía Exarmed (para el Examen de Aspirantes a Residencias Médicas) 
  Chapter: Enfermedades de los nervios craneales. (Cranial Nerves Diseases) 
  Ortega-Legaspi JM., López-Avila AEditors: González Quesada CJ., Romano Munive AF.Intersistemas, México2008
• Frontiers in Pain Research 
  Chapter: The Affective and Cognitive Dimension of Nociception in an Animal Model: The Role of the Anterior Cingulate Cortex 
  Pellicer F., Torres-López E., Sotres-Bayón F., López-Avila A, Coffeen U., Ortega-Legaspi J.M., del Ángel REditors: Lucas A.Nova Science Publishers, Inc., New York, NY2006
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Abstracts/Posters

• Major Histocompatibility Complex-I Deficient Embryonic Stem Cell Derived Cardiomyocytes as Potential off-the-Shelf Therapy for Cardiac Regeneration
  Ortega-Legaspi JM, Chyu J, Zhang Y, El-Nachef D, Oyama K, Gornalusse GG, Russell DW, MacLellan WR, International Society for Stem Cell Research, Boston, MA, 1/1/2017
• Echocardiographic Findings in Continuous-Flow Left Ventricular Assist Device Pump Thrombosis
  Ortega-Legaspi JM, Airhart S, Nguyen H, Masri SC, Mokadam NA, Mahr C, Kirkpatrick JN, Heart Failure Society of America 20th Annual Scientific Meeting, Orlando, FL, 1/1/2016
• Major Histocompatibility Complex-I Deficient Embryonic Stem Cell-Derived Cardiomyocytes as Potential Off The-Shelf Therapy For Cardiac Regeneration
  Ortega-Legaspi JM, Chyiu J, de la Mata A, MacLellan WR, World Congress of Cardiology and Cardiovascular Health. World Heart Federation, Mexico City, 1/1/2016
• Tracking the Footprint Effect of Nerve Damage on the Brain’s Pain Matrix: Bold Study in Rat
  Pellicer F, Ortega-Legaspi JM, Martín R, Solís-Nájera S, Magis-Weinberg L, Graff-Guerrero A, de la Fuente-Sandoval C, Rodriguez A, Fifth International Congress on Neuropathic Pain, Nice, France, 1/1/2015
• Prevalence and Characteristics of Patients Eligible for Catheter-Based Renal Arterial Denervation in an Academic Cardiology Clinic
  Hayek SS, Abdou MH, Demoss BD, Ortega-Legaspi JM, Veledar E, Deka A, Krishnan SK, Wilmot KA, Patel AD, Kumar V, Pudi M, Devireddy CM, ACC Scientific session, San Francisco, CA, 1/1/2013
• Challenges in Defining Resistant Hypertension: Prevalence among Hypertensive Outpatients Varies With Inclusion of Diuretic Use and Medication Dosing
  Hayek SS, Deka A, Krishnan SK, Ortega-Legaspi JM, DeMoss BD, Wilmot KA, Abdou MH, Patel AD, Kumar VR, Veledar E, Devireddy CM, AHA-HBPR scientific session, 1/1/2012
• Alginate microencapsulation of human mesenchymal stem cells as a strategy to enhance paracrine-mediated vascular recovery after hind limb ischemia
  Landázuri N, Levit RD, Joseph G, Ortega-Legaspi JM, Flores CA, Weiss D, Sambanis A, Weber CJ, Safley SA, Taylor WR, 9th Annual Resident Research Day, J Willis Hurst Internal Medicine Residency Program, Emory University School of Medicine, Atlanta, GA, 1/1/2012
• Expression of the dopaminergic D1 and D2 receptors in the anterior cingulate cortex in a model of neuropathic pain
  Ortega-Legaspi JM, de Gortari P, Garduño-Gutiérrez R, Amaya MI, León-Olea M, Coffeen U, Pellicer F, 9th Annual Resident Research Day, J Willis Hurst Internal Medicine Residency Program, Emory University School of Medicine, Atlanta, GA, 1/1/2012
• Role of the cholinergic muscarinic system in the anterior cingulate cortex in the modulation of neuropathic and inflammatory pain
  Ortega-Legaspi JM, León-Olea M, de Gortari P, Amaya MI, Coffeen U, Simón-Arceo K, Pellicer F, 8th Annual Resident Research Day, J Willis Hurst Internal Medicine Residency Program, Emory University School of Medicine, Atlanta, GA, 1/1/2011
• Stridor in the Adult Patient
  Torgersen J, Ortega-Legaspi J, Ilksoy N, Martin G, Southern Hospital Medicine Conference, New Orleans, LA, 1/1/2011
• Inflammatory Nociception Increases Dopamine D2 Receptors in the Rat´s Insular Cortex
  Coffeen U, de Gortari P, Amaya MI, Ortega-Legaspi JM, Simón-Arceo K, Pellicer F, 13th World Congress on Pain, Montreal, Canada, 1/1/2010
• Changes of Dopaminergic D1 and D2 Receptors mRNA in the Anterior Cingulate Cortex Associated with Neuropathic Nociception
  Pellicer F, Ortega-Legaspi JM, de Gortari P, Amaya MI, Coffeen U, Simón-Arceo K, Third International Congress on Neuropathic Pain, Athens, Greece, 1/1/2010
• Dolor Neuropático (Neuropathic Pain)
  Ortega-Legaspi JM, Fibromialgia: Cuando el dolor se convierte en enfermedad, Instituto Nacional de Psiquiatría Ramón de la Fuente, México D.F., 1/1/2009
• Expresión de mRNA para los receptores dopaminérgicos D1 y D2 en la corteza anterior del cíngulo en un modelo de dolor neuropático (Expression of mRNA for dopaminergic ...
  Ortega-Legaspi JM, de Gortari P, Amaya MI, Pellicer F, XIV Encuentro Nacional de Investigadores, Comisión Coordinadora de Institutos Nacionales de Salud y Hospitales de Alta Especialidad. Secretarí, 1/1/2009
• Cholinergic M2, but not M1, receptor immunoreactivity expression diminishes in the anterior cingulate cortex in a neuropathic model of nociception
  Ortega-Legaspi JM, León-Olea M, Melo A, Lamothe-Molina P, Simón-Arceo K, López-Avila A, Coffeen U, Jaimes O, Pellicer F, Pain in Europe VI, 6th Congress of the European Federation of IASP Chapters (EFIC), Lisbon, Portugal, 1/1/2009
• Complete Cholinergic Muscarinic Blockage in Hippocampal Regions CA1 and CA3 Diminishes Neuropathic Nociception
  Pellicer F, Bermudez P, de Rienzo B, López-Avila A, Melo A, Lamothe-Molina P, Simón-Arceo K, Coffeen U, Jaimes O, Ortega-Legaspi JM, Pain in Europe VI, 6th Congress of the European Federation of IASP Chapters (EFIC), Lisbon, Portugal, 1/1/2009
• Inflammatory nociception diminishes dopamine release in the insular cortex of the rat
  Coffeen U, Jaimes O, Simón-Arceo K, Ortega-Legaspi JM, López-Avila A, Pellicer F, Pain in Europe VI, 6th Congress of the European Federation of IASP Chapters (EFIC), Lisbon, Portugal, 1/1/2009
• Electrical stimulation of the insular cortex diminishes nociceptive behaviour and increases theta frequency band in rats
  Simón-Arceo K, Coffeen U, Palma M, Ortega-Legaspi JM, López-Avila A, Pellicer F, Pain in Europe VI, 6th Congress of the European Federation of IASP Chapters (EFIC), Lisbon, Portugal, 1/1/2009
• A Chronic Animal Model for the Study of Migraine
  López-Avila A, Melo A, Simón-Arceo K, Coffeen U, Lamothe-Molina P, Ortega-Legaspi JM, Pellicer F, Castillo-Tovar A, Jaimes O, Pain in Europe VI, 6th Congress of the European Federation of IASP Chapters (EFIC), Lisbon, Portugal, 1/1/2009
• Opposite parietal and midbrain BOLD patterns during inflammatory pain in the rat: A high-field fMRI study
  Graff-Guerrero A, Ortega-Legaspi JM, de la Fuente-Sandoval C, Pellicer F, López D, Moreno A, Martín R, Solis S, Hidalgo S, Rodriguez AO, International Society for Magnetic Resonance in Medicine Congress, Honolulu, HI, 1/1/2009
• La administración sistémica de un agonista parcial D2 (aripiprazol), disminuye la nocicepción en un modelo de dolor neuropático en la rata
  Pellicer F., López-Avila A., Coffeen U., Ortega-Legaspi JM., Jaimes O, XIII Encuentro Nacional de Investigadores, Comisión Coordinadora de Institutos Nacionales de Salud y Hospitales de Alta Especialidad. Secretarí, 1/1/2008
• Mecanismos de memoria y dolor (Mechanisms of Memory and Pain)
  Ortega-Legaspi JM, El dolor: Estudio y abordaje, Instituto Nacional de Psiquiatría Ramón de la Fuente, México D.F., 1/1/2008
• The Role of Cholinergic M1, M2, M3 and M4 Receptors in the Anterior Cingulate Cortex Regarding Nociceptive Related Memory in the Rat
  Ortega-Legaspi JM, López-Avila A, Coffeen U, Castillo-Tovar A, Lamothe-Molina P, Jaimes O, Pellicer F, 12th World Congress on Pain, Glasgow, Scotland, United Kingdom, 1/1/2008
• López-Avila A, Lamothe-Molina P, Ortega-Legaspi JM, Coffeen U, Jaimes O, Castillo-Tovar A, Pellicer F, 12th World Congress on Pain, Glasgow, Scotland, United Kingdom, 1/1/2008
• Single and Daily Doses of Aripiprazole, a Dopamine D2 Partial Agonist, Diminish Nociception in a Neuropathic Pain Model in the Rat
  Pellicer F, Ortega-Legaspi JM, López-Avila A, Coffeen U, Lamothe-Molina P, Castillo-Tovar A, Jaimes O, 12th World Congress on Pain, Glasgow, Scotland, United Kingdom, 1/1/2008
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Lectures

• Cells Therapy and Cardiovascular Disease 
  University of Washington - 1/1/2017
• Inicio y seguimiento del tratamiento inmunosupresor del paciente pos-trasplante (Initiation and following of immunosuppressive therapy in post transplant patients) 
  Jalisco, México - 1/1/2017
• Apoyo Mecánico Circulatorio en Pacientes con Insuficiencia Cardíaca Terminal (Mechanical Circulatory Support in Patients with End Stage Heart Failure) 
  Jalisco, México - 1/1/2017
• Stem Cells in the Heart: Past, Present and Future Directions 
  University of Washington - 1/1/2016
• The teaching of medicine: being doctors 
  Emory University - 1/1/2013
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