JoshuaNGoldsteinMDPhD

PubMed

• Optimal Magnitude of Blood Pressure Reduction and Hematoma Growth and Functional Outcomes in Intracerebral Hemorrhage.
  Qi Li, Xinni Lv, Andrea Morotti, Adnan I Qureshi, Dar Dowlatshahi
  Neurology. 2025-03-11
• Implementation and assessment of a one-month sabbatical program for faculty in an academic emergency department.
  Kian D Samadian, Joshua N Goldstein, Ali S Raja, Joshua J Baugh
  Academic Emergency Medicine. 2025-02-21
• Emergency Priorities in the Treatment of Cerebral Hemorrhage: Code-Intracerebral Hemorrhage.
  Madeleine M Puissant, Stephan A Mayer, Joshua N Goldstein
  Neurologic Clinics. 2025-02-01

Journal Articles

• A Pooled Analysis of Diffusion-Weighted Imaging Lesions in Patients with Acute Intracerebral Hemorrhage  
  Santosh B Murthy, Babak B Navi, Pitchaiah Mandava, Guido J Falcone, Kevin N Sheth, Jonathan Rosand, Adnan I Qureshi, Joshua N Goldstein, Magdy Selim, Daniel F Hanley, ..., JAMA Neurology
• Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Ass...  
  Hemphill JC 3rd, Greenberg SM, Anderson CS, Becker K, Bendok BR, Cushman M, Fung GL, Goldstein JN, Macdonald RL, Mitchell PH, Scott PA, Selim MH, Woo D., Stroke, 1/28/2015
• Rare Coding Variation and Risk of Intracerebral Hemorrhage  
  Radmanesh, F., Falcone, G.J., Anderson, C.D., Devan, W.J., Battey, T.W., Ayres, A.M., Raffeld, M.R., Schwab, K., Goldstein, J.N., Viswanathan, A., Greenberg, S.M., Lan..., Stroke, 1/25/2015
• Four-factor prothrombin complex concentrate is superior to plasma for rapid vitamin K antagonist reversal in patients requiring urgent surgical interventions: a random...  
  Goldstein, J.N., Refaai, M.A., Milling, T.J., Lewis, B., Goldberg-Alberts, R., Hug, B.A., Sarode, R., Lancet, 1/23/2015
• Thromboembolic Events after Vitamin K Antagonist Reversal with Four-Factor Prothrombin Complex Concentrate: Exploratory Analyses of Two Randomized, Plasma-controlled S...  
  Milling, T.J., Refaai, M.A., Goldstein, J.N., Schneider, A., Omert, L., Harman, A., Lee, M.L., Sarode, R, Annals of Emergency Medicine, 1/17/2015
• Lung-Protective Ventilation With Low Tidal Volumes and the Occurrence of Pulmonary Complications in Patients Without Acute Respiratory Distress Syndrome: A Systematic ...  
  Serpa Neto A, Simonis FD, Barbas CS, Biehl M, Determann RM, Elmer J, Friedman G, Gajic O, Goldstein JN, Linko R, Pinheiro de Oliveira R, Sundar S, Talmor D, Wolthuis E..., Crit Care Med, 1/15/2015
• Rate of Contrast Extravasation on CTA Predicts Hematoma Expansion and Mortality in Primary Intracerebral Hemorrhage  
  Brouwers, H.B., Battey, T.W., Husial, H.H., Ciura, V.A., Falcone, G.J., Ayres, A.M., Vashkevich, A., Schwab, K., Viswanathan, A., Anderson, C.D., Greenberg, S.M., Pome..., Stroke, 1/4/2015
• Increased risk of volume overload with plasma compared with four-factor prothrombin complex concentrate for emergency vitamin K antagonist reversal  
  Refaai, M.A., Goldstein, J.N., Lee, M.L., Durn, B.S., Milling, T.J., Sarode, R, Transfusion, 1/1/2015
• Reversal strategies for vitamin K antagonists in acute intracerebral hemorrhage  
  Parry-Jones, A.R., Di Napoli, M., Goldstein, J.N., Schreuder, F., Tetri, S., Tatlisumak, T., Yan, B., van Nieuwenhuizen, K., Dequatre-Ponchelle, N., Lee-Archer, M., Ho..., Annals of Neurology, 1/1/2015
•  
  Falcone, G.J., Radmanesh, F., Brouwers, H.B., Battey, T.W.K., Devan, W.J., Valant, V., Chitsike, L.P., Ayres, A., Schwab, K., Goldstein, J.N., Viswanathan, A., Greenbe..., Neurology, 1/23/2014
• Very Early Administration of Progesterone for Acute Traumatic Brain Injury  
  Wright, DW et al., N Engl J. Med, 1/10/2014
• Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage  
  Woo, D., Falcone, G.J., Devan WJ, Brown WM, Biffi A, Howard TD, Anderson CD, Brouwers HB, Valant V, Battey TW, Radmanesh F, Raffeld MR, Baedorf-Kassis S, Deka R, Woo J..., Am J Hum Genet, 1/3/2014
• CT Angiography Spot Sign in Intracerebral Hemorrhage Predicts Active Bleeding During Surgery  
  Brouwers HB, Raffeld MR, van Nieuwenhuizen K., Falcone, G.J., Ayres, A.M., McNamara, K.A., Schwab, K., Romero, J.M., Velthuis, B.K., Viswanathan, A., Greenberg, S.M., ..., Neurology, 1/2/2014
• Association between tidal volume size, duration of ventilation, and sedation needs in patients without acute respiratory distress syndrome: an individual patient data ...  
  Serpa Neto A, Simonis FD, Barbas CS, Biehl M, Determann RM, Elmer J, Friedman G, Gajic O, Goldstein JN, Horn J, Juffermans NP, Linko R, de Oliveira RP, Sundar S, Talmo..., Intensive Care Med, 1/1/2014
• Risk Factors for CT Angiography Spot Sign in Deep and Lobar Intracerebral Hemorrhage are Shared  
  Radmanesh F, Falcone GJ, Anderson CD, Battey TWK, Ayres AM, Vashkevich A, McNamara KA, Schwab K, Romero JM, Viswanathan A, Greenberg SM, Goldstein JN, Rosand J, Brouwe..., Stroke, 1/1/2014
• Spot sign on 90 second delayed computed tomograph angiography improves sensitivity for hematoma expansion and mortality: prospective study  
  Ciura, V.A., Brouwers, H.B., Pizzolato, R., Ortiz, C.J., Rosand, J., Goldstein, J.N., Greenberg, S.M., Pomerantz, S.R., Gonzalez, R.G., Romero, J.M., Stroke, 1/1/2014
• Anatomic Pattern of Intracerebral Hemorrhage Expansion: Relation to Spot Sign and Hematoma Center  
  Boulouis, G. Dumas, A., Betensky, R.A., Brouwers, H.B., Fotiadis, P., Vashkevich, A., Ayres, A., Schwab, K., Viswanathan, A., Goldstein, J.N., Rosand, J., Gurol, M.E.,..., Stroke, 1/1/2014
• Dizziness  
  Chase M, Goldstein JN, Selim MH, Pallin DJ, Camacho MA, O'Connor JL, Ngo L, Edlow JA, Mayo Clin Proc, 1/1/2014
• Improving Door to Needle Times: A Single Center Validation of the Target Stroke Hypothesis  
  Ruff, I.M., Syed, A., Rost, N., Goldstein, J.N., Lev, M., Copen, W., Mcintyre, J., Schwamm, L, Stroke, 1/1/2014
• Antihypertensive Treatment of Acute Cerebral Hemorrhage Study Investigators Increased Brain Volume Among Good Grade Patients with Intracerebral Hemorrhage Results from...  
  Qureshi AI, Majidi S, Gilani WI, Palesch YY, Martin R, Novitzke J, Cruz-Flores S, Ehtisham A, Goldstein JN, Kirmani JF, Hussein HM, Suri MF, Tariq N, Neurocrit Care, 1/1/2014
• Efficacy and safety of a four-factor prothrombin complex concentrate (4F-PCC) in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma...  
  Sarode, R., Milling, T.J., Refaai, M.A., Mangione, A., Schneider, A., Durn, B.L., Goldstein, J.N., Circulation, 1/10/2013
• A Pathway-Based Gene Set Analysis of Oxidative Phosphorylation in Ischemic and Hemorrhagic Stroke  
  Anderson, C.D., Biffi, A., Nalls, M.A., Devan, W.J., Schwab, K., Ayres, A., Valant, V., Ross, O.A., Rost, N.S., Saxena, R., Viswanathan, A., Worrall, B.B., Brott, T.G...., Stroke, 1/1/2013
• Prospective Validation of the CT Angiography Spot Sign Score for Intracerebral Hemorrhage  
  Romero, J.M., Kelly, H.R., Brouwers, H.B., Delgado Almandoz, J., Goldstein, J., Heit, J., Gonzalez, R.G., Stroke, 1/1/2013
• Acute respiratory distress syndrome after spontaneous intracerebral hemorrhage  
  Elmer J, Hou P, Wilcox SR, Chang Y, Schreiber H, Okechukwu I, Pontes-Neto O, Bajwa E, Hess DR, Avery L, Duran-Mendicuti MA, Camargo CA, Greenberg SM, Rosand J, Pallin ..., Crit Care Med, 1/1/2013
• Spot sign score predicts rapid bleeding in spontaneous intracerebral hemorrhage  
  Romero, J. M., Heit, J., Delgado Almandoz, J., Goldstein, J.N., Lu, J., Halpern, E., Greenberg, S.M., Rosand, J., Gonzalez, R. G., Emergency Radiology, 1/19/2012
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Books/Book Chapters

• Rosen’s Emergency Medicine 
  Chapter: Stroke 
  Crocco, T, Goldstein, J. N.Editors: John A. Marx et al.Saunders Elsevier, Philadelphia, PAEdition 8th,2013
• Vascular Emergencies: Expert Management for the Emergency Physician 
  Chapter: Intracranial Hemorrhage 
  Nentwich, L.M., and Goldstein, J. N.Editors: Rob Rogers et al.Cambridge University Press, Cambridge, UK2013
• Emergency Medicine 
  Chapter: Bleeding Disorders 
  Levine, M., Goldstein, J. N.Editors: James G. Adams.Saunders Elsevier, Philadelphia, PAEdition 2nd,2012
• Neurology Emergencies 
  Chapter: Intracerebral Hemorrhage 
  Goldstein, J. N. and Rosand, JEditors: M. Selim and J. A. Edlow.Oxford University Press, New York, NY2011
• Essential Emergency Imaging 
  Chapter: Intracerebral Hemorrhage 
  Goldstein, J. N.Editors: Shah, K, Lewiss, R and Turan, S.Lippincott, Williams & Wilkins, Philadelphia, PA2011
• Essential Emergency Imaging 
  Chapter: Subarachnoid Hemorrhage 
  Thomas, L. E., Goldstein, J. N.Editors: Shah, K, Lewiss, R and Turan, S.Lippincott, Williams & Wilkins, Philadelphia, PA2011
• Emergency Medicine Practice 
  Chapter: Evidence-Based Approach To Diagnosis And Management Of Aneurysmal Subarachnoid Hemorrhage In The Emergency Department 
  Thomas, L. E., Edlow, J. A., Goldstein, J.N.Editors: A. Jagoda.2009
• Warfarin reversal in anticoagulant-associated intracerebral hemorrhage 
  Goldstein, J. N., Rosand, J., Schwamm, L.H.2008
• Coumarin Anticoagulant Research Progress 
  Chapter: Emergency Warfarin Reversal 
  Levine, M.L., Goldstein, J. N.Editors: Joseph P. Edardes.Nova Publishers, New York, NY2008
• Emergency Medicine 
  Chapter: Headache 
  Goldstein, J. N., Edlow, J.A.Editors: James G. Adams.Saunders Elsevier, Philadelphia, PA2008
• Emergency Medicine Research Advances 
  Chapter: Oral Anticoagulant Reversal in the Emergency Department 
  Levine, M. L., Goldstein, J. N.Editors: Diane M. Jenkins.Nova Publishers, New York, NY2008
• Continuum: Lifelong learning in neurology 
  Chapter: Emergency Management of Intracerebral Hemorrhage 
  Page 13 - 29Goldstein, J. N., Greenberg, S. M., Rosand, JLippincott Williams, Hagerstown, MD2006
• Signs and Symptoms in Emergency Medicine 
  Chapter: Headache 
  Goldstein, J. N., Edlow, J.A.Mosby Elsevier, Philadelphia, PA2006
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Lectures

• Stroke Prevention in NVAF: Optimizing the use of Oral Anticoagulants in the Emergency Department 
  Boston, MA - 1/1/2015
• Spot Sign in ICH: How Might it Guide Therapy? 
  Scottsdale, AZ - 1/1/2015
• Acute Intracerebral Hemorrhage: Current and Future State 
  Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI - 1/1/2015
• Emergency Diagnosis and Management of Acute Stroke 
  Boston, MA, 2007, 2008, 2010, 2011, 2013, 2014, 2015 - 1/1/2015
• Emergency Management of Acute Intracerebral Hemorrhage 
  Waltham, MA - 1/1/2015
• Reversing Coumadin – FFP or PCC? 
  Boston, MA - 1/1/2015
• Acute Ischemic Stroke 
  Boston, MA, 2013, 2015 - 1/1/2015
• Intracerebral Hemorrhage: Acute Blood Pressure Management 
  Utrecht, Netherlands - 1/1/2014
• Bleeding Complications of Targeted Oral Anticoagulants: What is the Risk? 
  San Francisco, CA - 1/1/2014
• Current Status of Telemedicine in Stroke Care 
  Chicago, IL - 1/1/2014
• Thrombolytics in Stroke: Practical Aspects for the Emergency Physician 
  Rush University Medical Center, Chicago, IL - 1/1/2014
• Wake-up Stroke 
  Dallas, TX - 1/1/2014
• Prothrombin Complex Concentrates for Intracerebral Hemorrhage 
  University of Washington Medical Center, Seattle, WA - 1/1/2014
• Revascularization in Stroke 
  Beverly Hospital, Beverly, MA - 1/1/2014
• Care for the Patient, Not the System 
  Uppsala, Sweden - 1/1/2014
• Emergency Reversal of Warfarin Prior to Surgery 
  Frankfurt, Germany - 1/1/2014
• Revascularization in Acute Stroke: Update 
  Boston, MA - 1/1/2013
• Stroke, Intracerebral hemorrhage 
  Boston, MA - 1/1/2013
• Massive Bleeding: Prothrombin Complex Concentrates vs. FFP 
  1/1/2013
• Challenges and Opportunities in the Treatment of Acute Ischemic Stroke: Key Points for the Emergency Physician 
  Good Samaritan Medical Center, West Palm Beach, FL - 1/1/2013
• Acute Stroke: Time to Thrombolysis 
  Little Rock, AK, 2012, 2013 - 1/1/2013
• A Decade of Stroke Thrombolysis: Consensus on Comparative Effectiveness, Shared Decision Making, and Timeliness of Care 
  1/1/2013
• Neurological Emergencies - The First Hours & It's Just You! 
  Harvard Medical School, Waltham, Massachusetts - 10/19/2012
• Simulation: Airway and Intubation 
  Boston, MA - 1/1/2012
• Challenges of tPA Administration 
  1/1/2012
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Other

• iCritical Care Podcast 
  Goldstein, J.N, Society of Critical Care Medicine
  www.sccm.org/icriticalcare
  1/1/2015
• Exception from Informed Consent: Ethics and Logistics 
  Goldstein, J.N., Fu, R., Academic Emergency Medicine
  1/1/2015
• Case Unknowns. Appendix, Newman-Toker DE, Edlow JA. TiTrATE: A Novel, Evidence-Based Approach to Diagnosing Acute Dizziness and Vertigo 
  Omron, R., Kattah, J., Kothari, S., Carmona, S., Goldstein, J.N., Neurol Clin
  https://connect.johnshopkins.edu/vertigooverview/
  1/1/2015
• Scientific American Emergency Medicine 
  Brown, D.F., Brown, C.A., Fix, M.L., Goldstein, J.N., Noble, V.E., Raja, A, Decker Ip
  https://www.deckerip.com/products/scientific-american-emergency-medicine/
  1/1/2015
• New Oral Anticoagulants 
  Goldstein, J.N, European Hematology Association Learning Center
  http://learningcenter.ehaweb.org/eha/2012/interview/91393/joshua.goldstein.new.oral.anticoagulants.html
  1/6/2014
• Emergency Reversal of Anticoagulation: Novel Agents 
  Levine, M. and Goldstein, J.N., Current Neurology and Neuroscience Reports
  1/1/2014
• An Evidence-Based Approach To Diagnosis And Management Of Subarachnoid Hemorrhage In The Emergency Department 
  Aisiku, I., Edlow, J.A., Goldstein, J.N., Thomas, L.E., Emergency Medicine Practice
  1/1/2014
• Bleeding Complications of Targeted Oral Anticoagulants: What is the Risk? 
  Levine, M., Goldstein, J.N., Hematology: American Society of Hematology Education Program
  1/1/2014
• Opening the Window of Time in Stroke Therapy: New Evidence for the Emergency Department 
  Jagoda, A.S., Goldstein, J.N., Gorelick, P., Guluma, K.Z., MedScape Emergency Medicine
  http://www.medscape.org/viewarticle/832109
  1/1/2014
• Stroke and TIA 
  Goldstein, J. N., Comprehensive Review of Emergency Medicine, Oakstone Publishing/CMEinfo
  www.cmeinfo.com
  1/15/2011
• Brain Abscess 
  Thomas, L.E., Goldstein, J. N., eMedicine from WebMD
  http://emedicine.medscape.com/article/781021-overview
  1/13/2010
• Extended analysis of the spot sign score's performance 
  Delgado Almandoz, J.E., Yoo, A. J., Stone, M.J., Schaefer, P.W., Goldstein, J.N., Rosand, J., Oleinik, A., Lev, M.H., Gonzalez, R.G., Romero, J.M., Nature Reviews Neurology
  http://www.nature.com/nrneurol/journal/v6/n6/full/nrneurol.2009.152-c1.html
  1/1/2010
• Transient Ischemic Attack 
  Goldstein, J. N., eMedicine from WebMD
  http://www.emedicine.com/emerg/topic604.htm
  1/23/2008
• The sooner there is a treatment, the better 
  Goldstein, J. N., Emedicine Intracerebral Hemorrhage Resource Center Newsletter
  1/1/2007
• Hemorrhage expansion is associated with clinical deterioration 
  Naradzay, J., Goldstein, J. N., Emedicine Intracerebral Hemorrhage Resource Center Newsletter
  http://www.emedicine.com/email/ich/issue1-4.htm
  1/1/2007
• Successful Strategies for Intracerebral Hemorrhage in a Patient Receiving Oral Anticoagulant Therapy 
  Goldstein, J. N., MedSite CME
  http://www.medsitecme.com/(zwcjjl45tznsoja2vdbqaumg)/IDetail/Default_Campaign/Default_Program//326//sponsor.aspx)
  1/1/2007
• Neurological Emergencies: Case Studies in Critical Diagnoses 
  Edlow, J. A. and Traub, S. J. (editors), Goldstein, J. N. (Course reviewer), Harvard Medical School CME Online
  1/1/2007
• Intracerebral hemorrhage 
  Cucchiara, B. L. (Author), Goldstein, J. N. (Editor), Emedicine CME
  http://www.ichcme.com/courses/
  1/1/2006
• MRI and CT for the Detection of Acute Intracerebral Hemorrhage 
  Goldstein, J. N., The HMS LLSA Review CME Online course
  1/1/2006
• In Concert: The LLSA Literature Review. Gamma Hydroxybutyric Acid (GHB) Intoxication 
  Goldstein, J. N., Bohan, J. S., Critical Decisions in Emergency Medicine
  1/1/2004
• In Concert: The LLSA Literature Review. Treatment of Acute Ischemic Stroke 
  Goldstein, J. N., Bohan, J. S., Critical Decisions in Emergency Medicine
  1/1/2004
• In ConCert: The LLSA Literature Review. Update on Emerging Infections: News from the Centers for Disease Control and Prevention. In: Critical Decisions in Emergency Me... 
  Goldstein, J.N., Bohan, J. S., American College of Emergency Physicians
  1/1/2003
• In ConCert: The LLSA Literature Review. Cocaine-Associated Chest Pain: How Common is Myocardial Infarction? In: Critical Decisions in Emergency Medicine 
  Goldstein, J. N., Bontempo, L. J., American College of Emergency Physicians
  1/1/2003
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