Joseph B Shrager MD

Thoracic Surgery•Palo Alto, CA

Adult General Thoracic Surgery

Professor, Cardiothoracic Surgery, Stanford University Medical Center

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300 Pasteur DrPalo Alto, CA 94304
Phone+1 650-723-4000

Summary

Dr. Joseph Shrager is a thoracic surgeon in Stanford, CA and is affiliated with Stanford Healthcare and the VA Palo Alto Health Care System. He received his medical degree from Harvard Medical School and has been in practice 29 years. He specializes in adult general thoracic surgery and and has extensive experience in surgical and multimodality treatment of lung cancer, thymoma, myasthenia gravis , emphysema, sympathectomy, esophageal cancer. He has more than 200 publications.

Education & Training

Mass General Brigham/Massachusetts General HospitalFellowship, Thoracic Surgery - Independent, 1995 - 1997
University of Pennsylvania Health SystemResidency, Surgery, 1988 - 1995
Harvard Medical SchoolClass of 1988
Amherst CollegeB.A., Summa Cum Laude, 1980 - 1984

Certifications & Licensure

CA State Medical License 2008 - 2025
PA State Medical License 1990 - 2008
American Board of Surgery Surgery
American Board of Thoracic Surgery Thoracic and Cardiac Surgery

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2007-2014
America's Top Doctors for Cancer Castle Connolly, 2006-2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013
“Top Doctors” US News and World Report, 2011
Elected Member American Surgical Association, 2009
“Guide to America’s Top Surgeons” Consumers’ Research Council of America, 2008
Philadelphia Magazine Castle Connolly, 2005-2008
Elected Member (must be elected by age 45) Society of Clinical Surgery, 2007
“America’s Top Doctors” Castle Connolly Medical, Ltd., based on peer evaluations, 2007
“America’s Top Doctors for Cancer” Castle Connolly Medical, Ltd., based on peer evaluations, 2006
Listed, “Guide to America’s Top Physicians” 2005
Elected Member American Association for Thoracic Surgery, 2002
“Top Docs” listings Philadelphia Magazine, 2002, 2005-2007
Listed in Consumers’ Guide to Top Doctors Center for the Study of Services, 2001
2nd Edward D. Churchill Research Scholarship American Association for Thoracic Surgery, 1999
William I Inouye Award for Excellence in Teaching Department of Surgery, University of Pennsylvania Sch. of Med., 1991
National Research Service Award National Institutes of Health, 1990
Havighurst Graduation Prize (top history thesis) Amherst College, 1984
Manstein Graduation Prize (top premed athlete) Amherst College, 1984
Simpson Fellowship (for study at Harvard Medical School) 1984
Jr. Phi Beta Kappa Amherst College, 1983
Top 1% of thoracic surgeons US News and World Report
Fellow (FACS) American College of Surgeons
Cabot Graduation Prize Harvard Medical School
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Clinical Trials

4D-CT-based Ventilation Imaging for Adaptive Functional Guidance in Radiotherapy Start of enrollment: 2009 Dec 01
Terminated
Early Phase 1
Safety and Effectiveness of a New Pleural Catheter for Symptomatic, Recurrent, MPEs Versus Approved Pleural Catheter Start of enrollment: 2016 May 01
Completed
Not Applicable
Lung Volume Reduction for Severe Emphysema by Stereotactic Ablative Radiation Therapy Start of enrollment: 2013 Feb 11
COMPLETED
NA

Publications & Presentations

PubMed

Initial patient characteristics of Thoracic Surgical Oncology Group 102: A multicenter prospective registry of active surveillance in patients with multiple ground-gla...
James Huang, Kay See Tan, Nasser Altorki, Mara Antonoff, Shanda Blackmon
The Journal of Thoracic and Cardiovascular Surgery. 2025-04-01
Three-Dimensional Printed Model of the Mediastinum for Cardiothoracic Surgery Resident Education.
Catherine T Byrd, Winston L Trope, H Henry Guo, Kyle Gifford, Prasha Bhandari
Annals of Thoracic Surgery Short Reports. 2025-03-01
Utility of PET for Nodal Staging in Subsolid Clinical Stage IA (T1 N0) Lung Adenocarcinoma.
Devanish N Kamtam, Joseph B Shrager, Irmina A Elliott, Henry H Guo, Brandon A Guenthart
Annals of Thoracic Surgery Short Reports. 2025-03-01

Journal Articles

Predictive Radiogenomics Modeling of EGFR Mutation Status in Lung Cancer
Daniel L Rubin, Gerald J Berry, Joseph B Shrager, Ann N Leung, H Henry Guo, Sandy Napel, Chuong D Hoang, Nature
MicroRNA-1 induces growth arrest and apoptosis in malignant mesothelioma
Xu Y, Zheng M, Merritt RE, Shrager JB, Wakelee H, Kratzke RA, Hoang CD, Chest, 7/14/2013
Diaphragm Muscle Atrophy in Mouse Following Long-Term Mechanical Ventilation
Tang HB , Lee M, Khuong AA, Wright E, Shrager JB, Muscle and Nerve., 1/1/2013
An observational study of circulating tumor cells and 18F-FDG PET uptake in patients with treatment-naive non-small cell lung cancer
Nair VS, Keu KV, Luttgen MS, Kolatkar A, Vasanawala M, Kuschner W, Bethel K, Iagaru AH, Hoh C, Shrager JB, Loo BW Jr, Bazhenova L, Nieva J, Gambhir SS, Kuhn P, PLOS One, 1/1/2013
Liquid chromatography/mass spectrometry methods for measuring dipeptide abundance in non-small-cell lung cancer
Wu M, Xu Y, Fitch WL, Zheng M, Merritt RE, Shrager JB, Zhang W, Dill DL, Peltz G, Hoang CD, Rapid Communications in Mass Spectroscopy, 1/1/2013
Lymph node evaluation achieved by open lobectomy compared with thoracoscopic lobectomy for N0 lung cancer
Merritt RE, Hoang CD, Shrager JB, Annals of Thoracic Surgery, 1/1/2013
A dominant adenocarcinoma with multifocal ground glass lesions does not behave as advanced disease
Gu B, Burt BM, Merritt RE, Stephanie S, Nair V, Hoang CD, Shrager JB, Annals of Thoracic Surgery, 1/1/2013
Sweet-Cordero EAA Rare Population of CD24+ITGB4+Notchhi Cells Drives Tumor Propagation in NSCLC and Requires Notch3 for Self-Renewal
Zheng Y, de la Cruz C, Sayles LC, Alleyne-Chin C, Vaka D, Knaak TD, Bigos M, Xu Y, Hoang CD, Shrager JB , Fehling HJ, French D, Forrest W, Jiang Z, Carano RAD, Barck ..., Cancer Cell, 1/1/2013
Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for CLCF1 and IL6 in non-small cell lung cancer in vivo
Vicent S, Sayles LC, Vaka D, Khatri P, Gevaert O, Chen R, Zheng Y, Gillespie AK, Clarke N, Xu Y, Shrager J, Hoang CD, Plevritis S, Butte A, Sweet-Cordero EA, Cancer Research, 1/1/2012
Prognostic PET 18F-FDG uptake imaging features are associated with major oncogenomic alterations in patients with resected non-small cell lung cancer
Nair VS, Gevaert O, Davidzon G, Napel S, Graves EE, Hoang CD, Shrager JB, Quon A, Rubin DL, Plevritis SK, Cancer Research, 1/1/2012
Oxidative stress-responsive microRNA-320a regulates glycolysis in diverse biological systems
Tang HB, Lee M, Sharpe O, Salamone L, Noonan E, Hoang CD, Levine S, Robinson WH, Shrager JB, FASEB Journal., 1/1/2012
Invited Commentary: A Comparative Study of Lung Sealants in a Porcine ex vivo Model
Shrager JB, Annals of Thoracic Surgery, 1/1/2012
Improved survival after pulmonary metastasectomy for soft tissue sarcoma
Predina JD, Puc MM, Bergey MR, Sonnad SS, Kucharczuk JC, Staddon A, Kaiser LR, Shrager JB, Journal of Thoracic Oncology, 1/1/2011
Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel fos, foxo1, stat3 – bim axis
Tang HB, Lee M, Budak MT, Pietras N, Hittinger S, Vu M, Khuong A, Hoang CD, Hussain SN, Levine S, Shrager JB, FASEB Journal, 1/1/2011
Benign Emptying of the Postpneumonectomy Space
Merritt RM, Reznik SI, DaSilva MC, Sugarbaker DJ, Whyte RI, Donahue DM, Hoang CD, Smythe WR, Shrager JB, Annals of Thoracic Surgery, 1/1/2011
Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer
Margaret M. Kozak, BS,* James D.Murphy, MD, MS,* Meike L. Schipper, MD,†Jessica S. Donington, MD,‡ Lisa Zhou, PhD,§ Richard I. Whyte, MD, MBA,§ Joseph B. Shrager, MD,..., Journal of Thoracic Oncology, 1/1/2011
Consensus definitions to promote an evidence-based approach to management of the pleural space A collaborative proposal by ESTS, AATS, STS, and GTSC
Brunelli A, Beretta E, Cassivi SD, Cerfolio RJ, Detterbeck F, Kiefer T, Miserocchi B, Shrager J, Singhal S, Van Raemdonck D, Verla G, European Journal of Cardiothoracic Surgery, 1/1/2011
Morbidity and mortality after esophagectomy following neoadjuvant chemoradiation
Merritt RE, Whyte RI, D’Arcy NT, Hoang CD, Shrager, JB, Annals of Thoracic Surgery, 1/1/2011
Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer
Merritt R, Shrager JB., Current Respiratory Medicine Reviews, 1/1/2011
Update on surgery for non-small cell lung cancer
Hoang CD, Shrager JB, Current Respiratory Medicine Reviews, 1/1/2011
Commentary on “Endobronchial Valves for Emphysema”
Shrager JB, New England Journal of Medicine., 1/1/2011
Society of Thoracic Surgeons Clinical Practice Guideline: The Prophylaxis and Management of Atrial Fibrillation following General Thoracic Surgery; Executive Summary
Fernando H, Jaklitsch M, Tisdale J, Walsh GL, Mitchell J, Shrager JB, Annals of Thoracic Surgery, 1/1/2011
Invited Commentary: Outcome of an Original Video-Assisted Thoracoscopic Extended Thymectomy for Thymoma
Shrager JB, Annals of Thoracic Surgery, 1/1/2011
Early outcomes following bilateral thoracoscopy vs median sternotomy for lung volume reduction
Puc M, Sonnad S, Shrager JB, Innovations, 1/1/2010
Should asymptomatic enlarged thymus glands be resected?
Singla S, Litzky LA, Kaiser LR, Shrager JB, Journal of Thoracic and Cardiovascular Surgery, 1/1/2010
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Press Mentions

Brompton Grand Rounds: Minimally Invasive Surgery-Thymic TumorsJuly 25th, 2022
Surgical Management of Non-Small-Cell Lung Cancer with Brain OligometastasesMay 17th, 2022
Congress Must Lower the Medicare Age to Save the Lives of Older AmericansJuly 29th, 2021
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