JosephIShapiroMD

PubMed

• An ode to valproic acid: A letter to the editor.
  Anna P Shapiro-Krew, Adele Viguera, Joseph Shapiro
  Pharmacological Research. 2024-01-01
• 1 citations
  Adipocyte Na, K-ATPase Signaling Attenuates Experimental Uremic Cardiomyopathy.
  Komal Sodhi, Xiaoliang Wang, Muhammad A Chaudhary, Hari Vishal Lakhani, Mishghan Zehra
  Cellular and Molecular Biology. 2023-05-31
• 3 citations
  Hypertonic Saline Infusion for Hyponatremia: Limitations of the Adrogué-Madias and Other Formulas.
  Brent Wagner, Deepak Malhotra, Darren Schmidt, Dominic S Raj, Zeid J Khitan
  Kidney360. 2023-04-01

Journal Articles

• Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure.  
  Haller, ST. EV Kolmakova, DJ Kennedy, AN Isachkina, A Shidyak, GV Budny, EV Folova, G Piecha, D Malhotra, OV Fedorova, JI Shapiro, and AY Bagrov, Am. J. Hypertens. 10:2012-17
• Magnetic resonance in the diagnosis and investigation of renal disease.  
  Chan, L., and J.I. Shapiro, Renal Failure 11:79-89
• Magnetic resonance spectroscopy study of renal transplant.  
  Chan L. and J.I. Shapiro, Renal Physiol. Biochem. 12:141-143
• Tubular hypermetabolism as a factor in the progression of chronic renal failure.  
  Schrier, R.W., D.C.H. Harris, J.I. Shapiro, L. Chan, and C. Carmelo, Am. J. Kid. Dis. 12:243-249
• Atrial natriuretic factor: physiologic and clinical aspects.  
  Schrier, R.W., R. Cosby, B. Yee, J. Durr, M. Nakamoto, L. Chan, and J.I. Shapiro, Asian-Pac. Cong. Neph. 3:137-143
• Groin heart transplantation in a model for NMR study.  
  Chan, L., C.E. Haug, and J.I. Shapiro, Ann. N. Y. Acad. Sci. 508:402-420
• NMR in the investigation and differential diagnosis of acute renal failure.  
  Chan, L., and J.I. Shapiro, Ann. N. Y. Acad. Sci. 508:420-421
• Ouabain-stimulated trafficking regulation of the Na/K-ATPase and NHE3 in renal proximal tubule cells.  
  Yan, Y, S Haller, A Shapiro, N Malhotra, J Tian, Z Xie, D Malhotra, JI Shapiro, and J Liu, Mol. Cell. Biochem. 367:175-93
• Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis.  
  Liu, C, Y Bai, Y Wang, Y Sottejeau, L Liu, X Li, JB LIngrel, D Malhotra, CJ Cooper, JI Shapiro, ZJ Xie, J Tian, J. Biol. Chem. 287:16390-8
• Down-regulation of the transcription factor snail in the placentas of patients with preeclampsia and in a rat model of preeclampsia.  
  Fedorva, L, C Gatto-Weis, S Smaili, N Khurshid, JI Shapiro, D Malhotra and T Horrigan, Reprod. Biol. Endocrinol. 10:15
• Measurement of intracellular sodium with NMR methods.  
  Hutchison, R.B. and J.I. Shapiro, Con. Mag. Reson. 3:215-236
• Competition between sodium pump and insulin induced endocytosis in renal epithelium: implication for blood pressure regulation.  
  Gupta, S, D Malhotra, J Liu, Z Xie, SM Najjar and JI Shapiro., Hypertension. 59:665-72
• Predictors of success on the United States medical licensing examinations (USMLE).  
  Gohara, S, JI Shapiro, AN Jacob, SA Khuder, RA Gandy, PJ Metting, J Gold and J Kleshinski, TLAR 16:11-20
• Prieurianin causes weight loss in diet induced obese mice and inhibits adipogenesis in cultured preadipocytes.  
  Kablan, A, RA Aunders, M Szkudalerk-Mikho, AJ Chin, RM Bosio, K Fujii, J Shapiro, KV Chin., J. Diabetes Metab. 1:1-12
• Prediction of mortality in ESRD patients using a feed forward neural netork developed from data submitted to the United States renal data system.  
  Jacob, A, S Khuder, N Malhotra, T Sodeman, JP Gold, D Malhotra and JI Shapiro, Nephron. 116:c148-158
• Cardiotonic steroid hormone marinobufagenin induces renal fibrosis: Implications of epithelial to mesenchymal transition.  
  Fedorova, L, V Raju, N El-Okdi, A Shidyak, S Vetteth, D Kennedy, S Vetteth, D Giovannucci, AY Bagrov, O Fedorova, JI Shapiro and D Malhotra, Am.J.Physiol. 296:F922- 34
• Hypokalemia potentiates ouabain’s effect on calcium cycling and cardiac growth.  
  Kennedy, D.J., M. Xie, S. Vetteth, D. Malhotra and J.I. Shapiro, Cell.Mol.Biol. 52(8):87-91
• Evidence supporting independent mechanisms for aldosterone and spironolactone induced inotropy in the rat heart.  
  Barbato, J.C., S. Rashid, P.J. Mulrow, J.I. Shapiro and R. Franco-Saenz, Hypertension. 44:751-757
• Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells.  
  Liu, J., S.M. Periyasamy, W. Gunning, O.V. Fedorova, A.Y. Bagrov, D. Malhotra, Z Xie, and J.I. Shapiro, Kidney Int. 62:2118- 2125
• Molecular insights into uremic cardiomyopathy: cardiotonic steroids and Na/K-ATPase signaling.  
  Kennedy, D.J., D. Malhotra and J.I. Shapiro, Cell.Mol.Biol. 52(8):3-14
• Molecular mechanisms of experimental salt- sensitive hypertension.  
  Joe, B. and JI Shapiro, JAHA
• Reactive oxygen species modulation of Na/K-ATPase regulates fibrosis and renal proximal tubular sodium handling.  
  Liu, J, DJ Kennedy, Y Yan, and JI Shapiro, Int. J Nephrol. 2012:381320
• Signaling through the Na/K- ATPase: Implications for Cardiac Fibrosis.  
  Shapiro, J.I. and J. Tian, Am.J.Physiol.-Heart and Circ. Physiol. 300:H29-30
• Endogenous cardiotonic steroids and hypertension.  
  Fedorova, O., JI Shapiro and AY Bagrov, Biochim. Biophys. Acta. 1802:1230-6
• Endogenous cardiotonic steroids: Physiology, pharmacology and novel therapeutic targets.  
  Fedorova, O., JI Shapiro and AY Bagrov, Pharm. Rev.61: 9-38
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Books/Book Chapters

• Critical Care Secrets. 
  Chapter: Acute renal failure 
  Ravindaran, A., and J.I. ShapiroEditors: P. Parsons.Mosby, Boston
• Cardiomyopathies. 
  Chapter: Cardiotonic steroids and cardiac fibrosis 
  Vetteth, S. S. Gohara, and J.I.ShapiroEditors: J. Veselka.Tech, Rojeka, Croatia
• Current Hypertension Reviews. 
  Chapter: Cardiotonic steroids, hypertension and cardiovascular disease 
  Gohara, S, D Malhotra, S Vetteth, and JI Shapiro
• Advances in Renal Physiology. 
  Chapter: Cardiotonic steroids, hypertension and cardiovascular disease 
  Gohara, S, D Malhotra, S Vetteth, and JI Shapiro
• Endocytosis, Structural Components, Functions and Pathways. 
  Chapter: The Na/K-ATPase and signaling 
  Liu, J and J.I. ShapiroNova Science Publishers, Inc
• Renal and Electrolyte Disorders. 
  Chapter: Pathogenesis and management of metabolic acidosis and alkalosis 
  Ratnam, S and J.I. ShapiroEditors: R. W. Schrier.Little Brown, BostonEdition 6,
• Critical Care Secrets. 
  Chapter: Acute renal failure 
  Kaw, .D. and J.I. ShapiroEditors: P. Parsons.Mosby, BostonEdition 4,
• Role of the Na/K-ATPase in Health and Disease. 
  Chapter: Role of cardiotonic steroids in uremic cardiomyopathy 
  Page 2036 - 2044Mohmand, B., D. Malhotra and J.I. ShapiroEditors: Bagrov, A.Y. and J.I. Shapiro.Frontiers in Bioscience
• Role of the Na/K-ATPase in Health and Disease. 
  Chapter: Introduction 
  Page 2020 - 2025Bagrov, A.Y. and J.I. ShapiroEditors: Bagrov, A.Y. and J.I. Shapiro.Frontiers in BioscienceEdition 10,
• Nephrology in 30 days. 
  Chapter: Respiratory and mixed acid-base disorders 
  Yoon, Y. and J.I. ShapiroEditors: R.F. Reilly and M.A. Perazella.Edition 1,
• Nephrology in 30 days. 
  Chapter: Simple acid-base disorders: Metabolic alkalosis 
  Kaw, D. and J.I. ShapiroEditors: R.F. Reilly and M.A. Perazella.
• Renal and Electrolyte Disorders Vth Edition. 
  Chapter: Pathogenesis and management of metabolic acidosis and alkalosis 
  Shapiro, J.I. and W.D. KaehnyEditors: R. W. Schrier.Little Brown, Boston
• Serono Symposium on Drugs and the Kidney. 
  Chapter: Pharmacological therapy of acute renal failure 
  Page 121 - 159Shapiro, J.I., D.C.H. Harris, and R.W. SchrierEditors: G. Remmuzzi.Raven Press, New York
• Principles and Practice of Hemodialysis. 
  Chapter: Dialysis considerations in the patient with acute renal failure 
  Venkatasen, J., J.I. Shapiro, and R.W. HamiltonEditors: W. Henrich.Mosby, Boston
• Renal and Electrolyte Disorders. 
  Chapter: Pathogenesis and management of metabolic acidosis and alkalosis 
  Shapiro, J.I. and W.D. KaehnyEditors: R. W. Schrier.Little Brown, BostonEdition 3,
• Campbell's Textbook of Urology. 
  Chapter: Etiology, pathogenesis and management of renal failure 
  Edelstein, C., Shapiro, J.I. and R.W. SchrierEditors: Philadelphia.W.B. Saunders Company
• Critical Care Secrets. 
  Chapter: Renal and electrolyte disturbances 
  Shapiro, J.IEditors: P. Parsons.Mosby Books, Philadelphia
• Renal and Electrolyte Disorders. 
  Chapter: Pathogenesis and management of metabolic acidosis and alkalosis 
  Shapiro, J.I. and W.D. KaehnyEditors: R. W. Schrier.Little Brown, BostonEdition 3,
• Campbell's Textbook of Urology. 
  Chapter: Etiology, pathogenesis and management of renal failure 
  Shapiro, J.I. and R.W. SchrierEditors: P.C. Walsh, A. B. Retik, T.A. Stamey and E. D. Vaughan.W.B. Saunders Company, Philadelphia
• Clinical Internal Medicine. 
  Chapter: Renal and electrolyte disorders 
  Page 125 - 178Shapiro, J.I., and R.W. SchrierEditors: R.W. Schrier.Little Brown, Boston
• In Proceedings of the 6th Asian Pacific Colloquium in Nephrology. 
  Chapter: Drug induced acute renal failure 
  Schrier, R.W., and J.I. ShapiroEditors: New York.Raven Press
• Proceedings of the 6th Asian Pacific Colloquium in Nephrology. 
  Chapter: Cellular events in ischemic acute renal failure 
  Page 22 - 38Schrier, R.W., and J.I. ShapiroRaven Press, New York
• 30th Congress of the Japanese Society of Dialysis Therapeutics. 
  Chapter: Clinical aspects of acute renal failure 
  Page 45 - 60Shapiro, J.I., and R.W. SchrierRaven Press, New York
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Lectures

• Spironolactone in Ischemic Renal Disease. 
  Brown University
• Endocytosis of the Na/K-ATPase in response to cardiotonic steroids. 
  Medical College of Ohio
• Hypertension; Current concepts. 
  Copper Mountain CME Update for Family Medicine
• Role of renal failure in cardiovascular disease. 
  Copper Mountain CME Update for Family Medicine
• Role Of Digitalis Like Substances In The Pathogenesis Of Uremic Cardiomyopathy. 
  Korotkov Symposium on Hypertension, St. Petersburgh, Russia
• Role of Cardiotonic Steroids in the Pathogenesis of Cardiac Fibrosis. 
  Fourth World Congress of Cellular and Molecular Biology. Poitiers, France
• Renal and Heart Disease: An Emerging Connection. 
  Medical University of Ohio
• Challenges in patient enrollment. 
  Nashville, Tennessee, 2006, Melbourne, Australia, 2007, Auckland, New Zealand, 2007
• Recurrent renal disease as a cause of graft loss. 
  Breckenridge Transplant Conference, Breckenridge, Colorado
• Digitalis – New Insights and Applications. 
  University of Toledo Health Science Campus
• Treatment of ischemic vascular disease. 
  Toledo Vascular Symposium
• Renal vascular disease; the case for the CORAL study. 
  Medical University of South Carolina, 2008, University of Cincinnati, 2008
• Ischemic Nephropathy. 
  Mercy Gilbert Medical Center
• Ischemic Nephropathy: The CORAL Trial. 
  Akron General Hospital
• Mechanism of action of spironolactone in the treatment of cardiac fibrosis. 
  University of Toledo
• Development and Use of Pegylated Albumin for Capillary Leak. 
  Baxter Healthcare Inc
• Uremic Cardiomyopathy. 
  Multiple Location, 2005, 2006, 2007, 2008, 2009, 2010
• Cardiotonic Steroids and Ischemic Renal Disease. 
  CORAL2 Planning Committee, Toledo, OH
• Role of Cardiotonic Steroids in Natriuresis, Hypertension and Renal Fibrosis: Update on 3rd Factor. 
  University of Colorado, 2009, University of Toledo, 2010
• Management Decisions in Renal Transplantation. 
  Breckenridge Transplant Conference
• Cardiotonic steroids, hypertension and progressive renal injury. 
  6th International Congress of Pathophysiology, Montreal, Canada
• Aging and the Kidney: Implications for Cardiovascular Disease. 
  International Conference on Aging, Pisa, Italy
• Update on the CORAL study. 
  National Institutes of Health, Bethesda, MD
• Cardiotonic steroids, natriuresis and hypertension. An update on 3rd factor. 
  Cleveland Clinic Foundation, Cleveland, OH, 2010, Wayne State University, 2010
• Cardiotonic steroids, renal fibrosis and hypertension. 
  International Society of Nephrology Meeting, Vancouver, Canada
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Other

• Hypertension and Diabetic Nephropathy. 
  Shapiro, J.I, World Hypertension League Website
  http://www.mco.edu/org/whl/prof.html#art
• Metabolic Acidosis: B.M.J. 
  Kaw, .D. and J.I. Shapiro, Point of Care