JosephIShapiroMD

PubMed

• 33 citations
  Phenotypic Alteration of Hepatocytes in Non-Alcoholic Fatty Liver Disease.
  Hari Vishal Lakhani, Dana Sharma, Michael W. Dodrill, Athar Nawab, Nitin Sharma
  International Journal of Medical Sciences. 2018-10-20
• 73 citations
  Renal insufficiency as a predictor of adverse events and mortality after renal artery stent placement.
  David J. Kennedy, William R. Colyer, Pamela S. Brewster, Mary Ankenbrandt, Mark W. Burket
  American Journal of Kidney Diseases. 2003-11-01
• 24 citations
  A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy
  Xiaoliang Wang, Muhammad A. Chaudhry, Ying Nie, Zijian Xie, Joseph I. Shapiro
  Journal of Visualized Experiments. 2017-11-07

Journal Articles

• Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure.  
  Haller, ST. EV Kolmakova, DJ Kennedy, AN Isachkina, A Shidyak, GV Budny, EV Folova, G Piecha, D Malhotra, OV Fedorova, JI Shapiro, and AY Bagrov, Am. J. Hypertens. 10:2012-17
• Magnetic resonance in the diagnosis and investigation of renal disease.  
  Chan, L., and J.I. Shapiro, Renal Failure 11:79-89
• Magnetic resonance spectroscopy study of renal transplant.  
  Chan L. and J.I. Shapiro, Renal Physiol. Biochem. 12:141-143
• Tubular hypermetabolism as a factor in the progression of chronic renal failure.  
  Schrier, R.W., D.C.H. Harris, J.I. Shapiro, L. Chan, and C. Carmelo, Am. J. Kid. Dis. 12:243-249
• Atrial natriuretic factor: physiologic and clinical aspects.  
  Schrier, R.W., R. Cosby, B. Yee, J. Durr, M. Nakamoto, L. Chan, and J.I. Shapiro, Asian-Pac. Cong. Neph. 3:137-143
• Groin heart transplantation in a model for NMR study.  
  Chan, L., C.E. Haug, and J.I. Shapiro, Ann. N. Y. Acad. Sci. 508:402-420
• NMR in the investigation and differential diagnosis of acute renal failure.  
  Chan, L., and J.I. Shapiro, Ann. N. Y. Acad. Sci. 508:420-421
• Ouabain-stimulated trafficking regulation of the Na/K-ATPase and NHE3 in renal proximal tubule cells.  
  Yan, Y, S Haller, A Shapiro, N Malhotra, J Tian, Z Xie, D Malhotra, JI Shapiro, and J Liu, Mol. Cell. Biochem. 367:175-93
• Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis.  
  Liu, C, Y Bai, Y Wang, Y Sottejeau, L Liu, X Li, JB LIngrel, D Malhotra, CJ Cooper, JI Shapiro, ZJ Xie, J Tian, J. Biol. Chem. 287:16390-8
• Down-regulation of the transcription factor snail in the placentas of patients with preeclampsia and in a rat model of preeclampsia.  
  Fedorva, L, C Gatto-Weis, S Smaili, N Khurshid, JI Shapiro, D Malhotra and T Horrigan, Reprod. Biol. Endocrinol. 10:15
• Measurement of intracellular sodium with NMR methods.  
  Hutchison, R.B. and J.I. Shapiro, Con. Mag. Reson. 3:215-236
• Competition between sodium pump and insulin induced endocytosis in renal epithelium: implication for blood pressure regulation.  
  Gupta, S, D Malhotra, J Liu, Z Xie, SM Najjar and JI Shapiro., Hypertension. 59:665-72
• Predictors of success on the United States medical licensing examinations (USMLE).  
  Gohara, S, JI Shapiro, AN Jacob, SA Khuder, RA Gandy, PJ Metting, J Gold and J Kleshinski, TLAR 16:11-20
• Prieurianin causes weight loss in diet induced obese mice and inhibits adipogenesis in cultured preadipocytes.  
  Kablan, A, RA Aunders, M Szkudalerk-Mikho, AJ Chin, RM Bosio, K Fujii, J Shapiro, KV Chin., J. Diabetes Metab. 1:1-12
• Prediction of mortality in ESRD patients using a feed forward neural netork developed from data submitted to the United States renal data system.  
  Jacob, A, S Khuder, N Malhotra, T Sodeman, JP Gold, D Malhotra and JI Shapiro, Nephron. 116:c148-158
• Cardiotonic steroid hormone marinobufagenin induces renal fibrosis: Implications of epithelial to mesenchymal transition.  
  Fedorova, L, V Raju, N El-Okdi, A Shidyak, S Vetteth, D Kennedy, S Vetteth, D Giovannucci, AY Bagrov, O Fedorova, JI Shapiro and D Malhotra, Am.J.Physiol. 296:F922- 34
• Hypokalemia potentiates ouabain’s effect on calcium cycling and cardiac growth.  
  Kennedy, D.J., M. Xie, S. Vetteth, D. Malhotra and J.I. Shapiro, Cell.Mol.Biol. 52(8):87-91
• Evidence supporting independent mechanisms for aldosterone and spironolactone induced inotropy in the rat heart.  
  Barbato, J.C., S. Rashid, P.J. Mulrow, J.I. Shapiro and R. Franco-Saenz, Hypertension. 44:751-757
• Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells.  
  Liu, J., S.M. Periyasamy, W. Gunning, O.V. Fedorova, A.Y. Bagrov, D. Malhotra, Z Xie, and J.I. Shapiro, Kidney Int. 62:2118- 2125
• Molecular insights into uremic cardiomyopathy: cardiotonic steroids and Na/K-ATPase signaling.  
  Kennedy, D.J., D. Malhotra and J.I. Shapiro, Cell.Mol.Biol. 52(8):3-14
• Molecular mechanisms of experimental salt- sensitive hypertension.  
  Joe, B. and JI Shapiro, JAHA
• Reactive oxygen species modulation of Na/K-ATPase regulates fibrosis and renal proximal tubular sodium handling.  
  Liu, J, DJ Kennedy, Y Yan, and JI Shapiro, Int. J Nephrol. 2012:381320
• Signaling through the Na/K- ATPase: Implications for Cardiac Fibrosis.  
  Shapiro, J.I. and J. Tian, Am.J.Physiol.-Heart and Circ. Physiol. 300:H29-30
• Endogenous cardiotonic steroids and hypertension.  
  Fedorova, O., JI Shapiro and AY Bagrov, Biochim. Biophys. Acta. 1802:1230-6
• Endogenous cardiotonic steroids: Physiology, pharmacology and novel therapeutic targets.  
  Fedorova, O., JI Shapiro and AY Bagrov, Pharm. Rev.61: 9-38
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Books/Book Chapters

• Critical Care Secrets. 
  Chapter: Acute renal failure 
  Ravindaran, A., and J.I. ShapiroEditors: P. Parsons.Mosby, Boston
• Cardiomyopathies. 
  Chapter: Cardiotonic steroids and cardiac fibrosis 
  Vetteth, S. S. Gohara, and J.I.ShapiroEditors: J. Veselka.Tech, Rojeka, Croatia
• Current Hypertension Reviews. 
  Chapter: Cardiotonic steroids, hypertension and cardiovascular disease 
  Gohara, S, D Malhotra, S Vetteth, and JI Shapiro
• Advances in Renal Physiology. 
  Chapter: Cardiotonic steroids, hypertension and cardiovascular disease 
  Gohara, S, D Malhotra, S Vetteth, and JI Shapiro
• Endocytosis, Structural Components, Functions and Pathways. 
  Chapter: The Na/K-ATPase and signaling 
  Liu, J and J.I. ShapiroNova Science Publishers, Inc
• Renal and Electrolyte Disorders. 
  Chapter: Pathogenesis and management of metabolic acidosis and alkalosis 
  Ratnam, S and J.I. ShapiroEditors: R. W. Schrier.Little Brown, BostonEdition 6,
• Critical Care Secrets. 
  Chapter: Acute renal failure 
  Kaw, .D. and J.I. ShapiroEditors: P. Parsons.Mosby, BostonEdition 4,
• Role of the Na/K-ATPase in Health and Disease. 
  Chapter: Role of cardiotonic steroids in uremic cardiomyopathy 
  Page 2036 - 2044Mohmand, B., D. Malhotra and J.I. ShapiroEditors: Bagrov, A.Y. and J.I. Shapiro.Frontiers in Bioscience
• Role of the Na/K-ATPase in Health and Disease. 
  Chapter: Introduction 
  Page 2020 - 2025Bagrov, A.Y. and J.I. ShapiroEditors: Bagrov, A.Y. and J.I. Shapiro.Frontiers in BioscienceEdition 10,
• Nephrology in 30 days. 
  Chapter: Respiratory and mixed acid-base disorders 
  Yoon, Y. and J.I. ShapiroEditors: R.F. Reilly and M.A. Perazella.Edition 1,
• Nephrology in 30 days. 
  Chapter: Simple acid-base disorders: Metabolic alkalosis 
  Kaw, D. and J.I. ShapiroEditors: R.F. Reilly and M.A. Perazella.
• Renal and Electrolyte Disorders Vth Edition. 
  Chapter: Pathogenesis and management of metabolic acidosis and alkalosis 
  Shapiro, J.I. and W.D. KaehnyEditors: R. W. Schrier.Little Brown, Boston
• Serono Symposium on Drugs and the Kidney. 
  Chapter: Pharmacological therapy of acute renal failure 
  Page 121 - 159Shapiro, J.I., D.C.H. Harris, and R.W. SchrierEditors: G. Remmuzzi.Raven Press, New York
• Principles and Practice of Hemodialysis. 
  Chapter: Dialysis considerations in the patient with acute renal failure 
  Venkatasen, J., J.I. Shapiro, and R.W. HamiltonEditors: W. Henrich.Mosby, Boston
• Renal and Electrolyte Disorders. 
  Chapter: Pathogenesis and management of metabolic acidosis and alkalosis 
  Shapiro, J.I. and W.D. KaehnyEditors: R. W. Schrier.Little Brown, BostonEdition 3,
• Campbell's Textbook of Urology. 
  Chapter: Etiology, pathogenesis and management of renal failure 
  Edelstein, C., Shapiro, J.I. and R.W. SchrierEditors: Philadelphia.W.B. Saunders Company
• Critical Care Secrets. 
  Chapter: Renal and electrolyte disturbances 
  Shapiro, J.IEditors: P. Parsons.Mosby Books, Philadelphia
• Renal and Electrolyte Disorders. 
  Chapter: Pathogenesis and management of metabolic acidosis and alkalosis 
  Shapiro, J.I. and W.D. KaehnyEditors: R. W. Schrier.Little Brown, BostonEdition 3,
• Campbell's Textbook of Urology. 
  Chapter: Etiology, pathogenesis and management of renal failure 
  Shapiro, J.I. and R.W. SchrierEditors: P.C. Walsh, A. B. Retik, T.A. Stamey and E. D. Vaughan.W.B. Saunders Company, Philadelphia
• Clinical Internal Medicine. 
  Chapter: Renal and electrolyte disorders 
  Page 125 - 178Shapiro, J.I., and R.W. SchrierEditors: R.W. Schrier.Little Brown, Boston
• In Proceedings of the 6th Asian Pacific Colloquium in Nephrology. 
  Chapter: Drug induced acute renal failure 
  Schrier, R.W., and J.I. ShapiroEditors: New York.Raven Press
• Proceedings of the 6th Asian Pacific Colloquium in Nephrology. 
  Chapter: Cellular events in ischemic acute renal failure 
  Page 22 - 38Schrier, R.W., and J.I. ShapiroRaven Press, New York
• 30th Congress of the Japanese Society of Dialysis Therapeutics. 
  Chapter: Clinical aspects of acute renal failure 
  Page 45 - 60Shapiro, J.I., and R.W. SchrierRaven Press, New York
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Lectures

• Spironolactone in Ischemic Renal Disease. 
  Brown University
• Endocytosis of the Na/K-ATPase in response to cardiotonic steroids. 
  Medical College of Ohio
• Hypertension; Current concepts. 
  Copper Mountain CME Update for Family Medicine
• Role of renal failure in cardiovascular disease. 
  Copper Mountain CME Update for Family Medicine
• Role Of Digitalis Like Substances In The Pathogenesis Of Uremic Cardiomyopathy. 
  Korotkov Symposium on Hypertension, St. Petersburgh, Russia
• Role of Cardiotonic Steroids in the Pathogenesis of Cardiac Fibrosis. 
  Fourth World Congress of Cellular and Molecular Biology. Poitiers, France
• Renal and Heart Disease: An Emerging Connection. 
  Medical University of Ohio
• Challenges in patient enrollment. 
  Nashville, Tennessee, 2006, Melbourne, Australia, 2007, Auckland, New Zealand, 2007
• Recurrent renal disease as a cause of graft loss. 
  Breckenridge Transplant Conference, Breckenridge, Colorado
• Digitalis – New Insights and Applications. 
  University of Toledo Health Science Campus
• Treatment of ischemic vascular disease. 
  Toledo Vascular Symposium
• Renal vascular disease; the case for the CORAL study. 
  Medical University of South Carolina, 2008, University of Cincinnati, 2008
• Ischemic Nephropathy. 
  Mercy Gilbert Medical Center
• Ischemic Nephropathy: The CORAL Trial. 
  Akron General Hospital
• Mechanism of action of spironolactone in the treatment of cardiac fibrosis. 
  University of Toledo
• Development and Use of Pegylated Albumin for Capillary Leak. 
  Baxter Healthcare Inc
• Uremic Cardiomyopathy. 
  Multiple Location, 2005, 2006, 2007, 2008, 2009, 2010
• Cardiotonic Steroids and Ischemic Renal Disease. 
  CORAL2 Planning Committee, Toledo, OH
• Role of Cardiotonic Steroids in Natriuresis, Hypertension and Renal Fibrosis: Update on 3rd Factor. 
  University of Colorado, 2009, University of Toledo, 2010
• Management Decisions in Renal Transplantation. 
  Breckenridge Transplant Conference
• Cardiotonic steroids, hypertension and progressive renal injury. 
  6th International Congress of Pathophysiology, Montreal, Canada
• Aging and the Kidney: Implications for Cardiovascular Disease. 
  International Conference on Aging, Pisa, Italy
• Update on the CORAL study. 
  National Institutes of Health, Bethesda, MD
• Cardiotonic steroids, natriuresis and hypertension. An update on 3rd factor. 
  Cleveland Clinic Foundation, Cleveland, OH, 2010, Wayne State University, 2010
• Cardiotonic steroids, renal fibrosis and hypertension. 
  International Society of Nephrology Meeting, Vancouver, Canada
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Other

• Hypertension and Diabetic Nephropathy. 
  Shapiro, J.I, World Hypertension League Website
  http://www.mco.edu/org/whl/prof.html#art
• Metabolic Acidosis: B.M.J. 
  Kaw, .D. and J.I. Shapiro, Point of Care